Project description
Impact of whole-genome duplications on adaptation
Whole-genome duplication (WGD) is possibly the most severe mutation that an organism may undergo. WGDs are often fatal, but the resulting polyploids that survive the initial shock to cellular processes may ultimately thrive. Whether conditions created by WGDs are beneficial or detrimental to adaptation is a long-standing question in evolutionary biology. The EU-funded POLYGARCH project will combine cutting-edge evolutionary modelling, novel machine-learning tools, and multi-species genomic data from short- and long-read sequencing to determine how WGDs alter the genetic and genomic architecture of local adaptation. The results will increase scientific understanding of the evolutionary success of polyploids, provide insights into factors influencing the current distribution of polyploid populations and species, and help predict how polyploids respond to environmental change.
Objective
Whole-genome duplication (WGD) is arguably the most severe mutation that an organism may undergo. As such, WGDs are often fatal, but the resulting polyploids that survive the initial shock to cellular processes may ultimately thrive. Whether conditions created by WGDs are beneficial or detrimental to adaptation is a long-standing question in evolutionary biology, with important implications for domestication and crop breeding. A key determinant of evolutionary responses is the genetic and genomic architecture of adaptive traits: i.e. the control of phenotypes by one or many loci, the interactions between alleles, positions of loci in relation to genomic features, and structural arrangements. By combining cutting-edge evolutionary modelling, novel machine-learning tools, and multi-species genomic data from short- and long-read sequencing, I propose to determine how WGDs alter the genetic and genomic architecture of local adaptation. Such knowledge will advance our understanding of the evolutionary success of polyploids, provide insights into factors influencing the current distribution of polypoid populations and species, as well as yield important information for predicting how polyploids respond to environmental change.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences evolutionary biology
- natural sciences biological sciences genetics mutation
- agricultural sciences agriculture, forestry, and fisheries agriculture agronomy plant breeding
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2020
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
NG7 2RD Nottingham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.