Project description DEENESFRITPL Revival of long-dormant viruses that infect bacteria Viruses trapped beneath permafrost for millions of years might revive as the Earth warms. The release of these ancient viruses may directly affect the population dynamics of present-day hosts. The EU-funded PermAVirThaw project aims to find out which viruses are archived in permafrost and which hosts they can infect. Viruses infecting plants and animals might pose major economic and human health threats. The project will find out how the presence and abundance of these viruses varies with permafrost age and type across the Arctic. It will also quantify the capacity of viral particles extracted from permafrost to infect present-day bacteria, and measure their impact on the role that bacteria play in carbon cycling. Show the project objective Hide the project objective Objective Around 17% of the Earth’s terrestrial surface is composed of permafrost, characterized by frozen ground for at least two consecutive years. Humanity has left Pandora's freezer door open. With the poles warming 3-times faster than the rest of the world, permafrost is being rapidly lost, potentially releasing ancient microbes locked in frozen soil. Accumulated evidences show that microbes, including viruses, locked in ancient permafrost can stay viable over millennia. However, little is known about viruses that froze alongside many of these microbial communities, and their release due to permafrost thaw may directly affect the population dynamics of present-day hosts. To understand these impacts, we need to determine which viruses are archived in permafrost and which hosts they can infect. Viruses infecting plants and animals might pose major economic and human health threats whereas viruses infecting microbes can transform ecological systems on which we rely. Therefore, the Fellowship goals are i) to determine how the virosphere varies with permafrost age and type across the Arctic; ii) to quantify the capacity of virions extracted from permafrost to infect present-day microbes; and iii) to measure the impact of permafrost extracted virions on present-day microbial community diversity and carbon cycling. The main outcomes will be large-scale knowledge on the composition of the ancient permafrost virosphere and the influence of age (including palaeoenvironment) on virus persistence and diversity, as well as their capacity to infect present-day microbes and change biogeochemical cycles. Fields of science natural sciencesbiological sciencesmicrobiologyvirologynatural sciencesbiological sciencesecologyecosystems Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2020 - Individual Fellowships Call for proposal H2020-MSCA-IF-2020 See other projects for this call Funding Scheme MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF) Coordinator THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Net EU contribution € 212 933,76 Address Trinity lane the old schools CB2 1TN Cambridge United Kingdom See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00