Improved predictions of antigen presentation and TCR recognition with MixMHCpred2.2 and PRIME2.0 reveal potent SARS-CoV-2 CD8+ T-cell epitopes
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Autori:
David Gfeller, Julien Schmidt, Giancarlo Croce, Philippe Guillaume, Sara Bobisse, Raphael Genolet, Lise Queiroz, Julien Cesbron, Julien Racle, Alexandre Harari
Pubblicato in:
Cell System, 2023, ISSN 2405-4720
Editore:
Cell Press
DOI:
10.1016/j.cels.2022.12.002
Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes
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Autori:
Juan Rodriguez-Rivas, Giancarlo Croce, Maureen Muscat, Martin Weigt
Pubblicato in:
Proceedings of the National Academy of Sciences, 2022, ISSN 1091-6490
Editore:
National Academy of Sciences
DOI:
10.1073/pnas.2113118119
Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
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Autori:
Julien Racle, Philippe Guillaume, Julien Schmidt, Justine Michaux, Amédé Larabi, Kelvin Lau, Marta A.S. Perez, Giancarlo Croce, Raphaël Genolet, George Coukos, Vincent Zoete, Florence Pojer,
Michal Bassani-Sternberg, Alexandre Harari, David Gfeller
Pubblicato in:
Immunity, 2023, ISSN 1097-4180
Editore:
Cell Press
DOI:
10.1016/j.immuni.2023.03.009
Both APRIL and antibody-fragment-based CAR T cells for myeloma induce BCMA downmodulation by trogocytosis and internalization
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Autori:
Nicolas Camviel, Benita Wolf, Giancarlo Croce, David Gfeller, Vincent Zoete, Caroline Arber
Pubblicato in:
Journal for Immunotherapy of Cancer, 2022, ISSN 2051-1426
Editore:
BMJ Publishing Group
DOI:
10.1136/jitc-2022-005091