Project description
Environmental chemical exposure weighs heavy on the heart
Toxic chemicals are omnipresent in the environment. From pesticides to drug traces in water, soil, air and living organisms, people are continuously exposed to a huge amount and variety of potentially toxic substances. At the same time, a growing occurrence of cardiovascular diseases has been observed, leading to the hypothesis that the two phenomena are related. To address this issue, the EU-funded ALTERNATIVE project will develop a platform that enables the identification, quantification and prevention of cardiotoxic co-exposures to industrial chemicals and pharmaceuticals. The platform will consist of a three-dimensional in vitro model mimicking the human cardiac tissue, coupled with a reliable, high-throughput monitoring system based on multi-omics analyses and integrated into a machine-learning risk assessment tool.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugs
- medical and health sciencesmedical biotechnologytissue engineering
- medical and health sciencesclinical medicinecardiologycardiovascular diseases
- natural sciencescomputer and information sciencesartificial intelligencemachine learning
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
10129 Torino
Italy
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Participants (10)
1050 Elsene
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6500 Svilengrad
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75011 Paris
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
00185 Roma
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08290 Cerdanyola Del Valles (Barcelona)
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69123 Heidelberg
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20156 Milano
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55054 Massarosa
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
3584 CS Utrecht
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6020 Innsbruck
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