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environmentAL Toxicity chEmical mixtuRes through aN innovative platform based on aged cardiac tissue model

Project description

Environmental chemical exposure weighs heavy on the heart

Toxic chemicals are omnipresent in the environment. From pesticides to drug traces in water, soil, air and living organisms, people are continuously exposed to a huge amount and variety of potentially toxic substances. At the same time, a growing occurrence of cardiovascular diseases has been observed, leading to the hypothesis that the two phenomena are related. To address this issue, the EU-funded ALTERNATIVE project will develop a platform that enables the identification, quantification and prevention of cardiotoxic co-exposures to industrial chemicals and pharmaceuticals. The platform will consist of a three-dimensional in vitro model mimicking the human cardiac tissue, coupled with a reliable, high-throughput monitoring system based on multi-omics analyses and integrated into a machine-learning risk assessment tool.

Call for proposal

H2020-LC-GD-2020

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Sub call

H2020-LC-GD-2020-3

Coordinator

POLITECNICO DI TORINO
Net EU contribution
€ 592 300,00
Address
Corso Duca Degli Abruzzi 24
10129 Torino
Italy

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Region
Nord-Ovest Piemonte Torino
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (10)

SCIENSANO
Belgium
Net EU contribution
€ 460 051,00
Address
Juliette Wytsmanstraat 14
1050 Elsene

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Research Organisations
Non-EU contribution
€ 0,00
SI ES TI EOOD
Bulgaria
Net EU contribution
€ 198 750,00
Address
Al. Stamobliysky 18
6500 Svilengrad

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Region
Югозападна и Южна централна България Южен централен Хасково
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ELVESYS
France
Net EU contribution
€ 473 218,75
Address
172 Rue De Charonne B2 2 Eme Etage
75011 Paris

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
Net EU contribution
€ 569 500,00
Address
Piazzale Aldo Moro 7
00185 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
FUNDACIO EURECAT
Spain
Net EU contribution
€ 1 439 437,50
Address
Avenida Universitat Autonoma 23
08290 Cerdanyola Del Valles (Barcelona)

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
EURESCOM-EUROPEAN INSTITUTE FOR RESEARCH AND STRATEGIC STUDIES IN TELECOMMUNICATIONS GMBH
Germany
Net EU contribution
€ 468 250,00
Address
Wieblinger Weg 19/4
69123 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Italy
Net EU contribution
€ 386 750,00
Address
Via Mario Negri 2
20156 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Research Organisations
Non-EU contribution
€ 0,00
IVTECH SRL
Italy
Net EU contribution
€ 306 750,00
Address
Via Di Bagnaia
55054 Massarosa

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Centro (IT) Toscana Lucca
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITEIT UTRECHT
Netherlands
Net EU contribution
€ 362 500,00
Address
Heidelberglaan 8
3584 CS Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
MEDIZINISCHE UNIVERSITAT INNSBRUCK
Austria
Net EU contribution
€ 242 250,00
Address
Christoph Probst Platz 1
6020 Innsbruck

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Region
Westösterreich Tirol Innsbruck
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00