Strategies for health protection, pollution Control and Elimination of Next generAtion RefractIve Organic chemicals from the Soil, vadose zone and water

Informations projet

SCENARIOS

N° de convention de subvention: 101037509

DOI

10.3030/101037509

Date de signature de la CE 2 Septembre 2021

Date de début 1 Novembre 2021

Date de fin 31 Octobre 2025

Financé au titre de

• SOCIETAL CHALLENGES - Climate action, Environment, Resource Efficiency and Raw Materials

Coût total

€ 11 985 716,25

Contribution de l’UE

€ 11 985 716,25

Coordonné par

UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO
Italy

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Other (4)

SCENARIOS workshop series

This Deliverable consists of the SCENARIOS Workshop Series (O, OTHER) planned along the project (three events). This report will gather each workshop agenda, outcomes, number of attendees and impacts (Output Task 10.4). The Deliverable will be due at M18 and updated in further Reports to the EC at M30 and 44.Deliverables also at M30, M44

SCENARIOS public communication materials (Intermediate)

This deliverable is the updated version of a collection of materials (O, OTHERS) produced for SCENARIOS communication (Input and Output Task, 10.1-10.5)

SCENARIOS project website

Launch of the project Website (O, Other). Moreover, Scenarios social networks will be created. A Report with information on the website will be also delivered. Main Input and Output Task is 10.1

SCENARIOS public communication materials (Draft)

This deliverable is a collection of materials (O, OTHERS) produced for SCENARIOS communication, including a poster, a project presentation, a brochure and annual newsletters (Input and Output Task, 10.1-10.5)

Demonstrators, pilots, prototypes (1)

Installation of monitoring systems for the unsaturated zone and groundwater at selected sites

A prototype vadose zone monitoring systems (VMS) for the study of PFAS transport will be installed and validated at real demo sites. An accompanying report featuring characteristic and performance will be prepared by Partner 4 (BGU) in collaboration with partner 5 (FOR), Partner 15 (ENV) and partner 17 (GEO). Input and output Tasks are T3.1 and T3.2.

Documents, reports (4)

Coordinated Policy Briefs on PFAS regulation

A brief Report will provide a practical structure to include the relevant information regarding the state-of-the-art policies on PFAS remediation. The deliverable will systematize the current large-scale regulations and highlight the agreement among operative procedures and requirements at local level, with special attention to gaps arising from lack of data, risk thresholds, and prescriptions. These results will be organised in order to identify the main gaps that can be covered by SCENARIOS solutions with regard to data acquisition and accessibility, LCA assessment, and new remediation solutions. Output Task 9.5. Input Task 9.5, T8.1-8.8. This Deliverable has the potential to contribute to new policy within the EU.Strong contribution to policy expected.

Report on LCA & LCC Results for SCENARIOS strategies

The deliverable is a Report -due at M12 (Draft version) and M36 (Final version)- conforming Output Task 8.1, Environmental Impact and Life Cycle Assessmentand Task 8.2, Economic Evaluation and Life Cycle Costing. Input Tasks are 8.1, 8.2, with possible inputs also from T6.1-6.4 and T7.3-7.4.Strong contribution to policy expected for approaches to address PFAS fate and costs in the environment. Each report will be structured as an LCA report presenting the results as indicated by ISO 14040. The systems to be evaluated with LCA will be defined according to the DEMOs realized in WP 7. For each system, the deliverable will describe all the elements necessary for the transparency of the LCA (scope functional unit, system boundaries, assumptions, data used for the analysis, software and databases applied, impact categories and impact assessment method, normalization and weighting strategies) and the associated results. Moreover, for the assessment of the Lifecycle Costing, Cost models, pricing systems and databases applied will be described.

Coordinated Policy briefs on risk assessment

Deliverable D99 will consist of a short document R Report that summarizes all the main findings available from the current literature and preliminary results on human and environmental hazardrisk assessments in respect to the current chemical legislation Eg REACHCLP Deliverable D47 will rely on the results and inputs from Tasks 41 to 48 it will conform Task 47 as well as T95 on regulation as output TasksStrong contribution to policy expected

SOP for sample storage and handling

The validated methodsprotocols for shipping storing and handling of samples will be described in a scientific report R report based on Task 21 Output Task The different sampling requirements for each type of sample water wastewater soil etc will be considered Subtask 211 and 212 The content of this report will serve as input for sample preparationhandling for multiple tasks in WP2 WP3 WP4 WP6 and WP7

Publications

Peer reviewed articles (15)

Impact of Legacy Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoate (PFOA) on GABA Receptor-Mediated Currents in Neuron-Like Neuroblastoma Cells: Insights into Neurotoxic Mechanisms and Health Implications

Auteurs: Laura Lagostena, Davide Rotondo, Davide Gualandris, Antonio Calisi, Candida Lorusso, Valeria Magnelli, Francesco Dondero
Publié dans: Journal of Xenobiotics, Numéro 14, 2024, Page(s) 1771-1783, ISSN 2039-4713
Éditeur: MDPI
DOI: 10.3390/jox14040094

Sensitive and accurate determination of 32 PFAS in human serum using online SPE-UHPLC-HRMS

Auteurs: Masho Hilawie Belay, Elisa Robotti, Arianna Ghignone, Alessia Fabbris, Jessica Brandi, Daniela Cecconi, Maria Angela Masini, Francesco Dondero, Emilio Marengo
Publié dans: Journal of Hazardous Materials, Numéro 485, 2024, Page(s) 136780, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2024.136780

Parameter grouping and co-estimation in physiologically based kinetic models using genetic algorithms

Auteurs: Periklis Tsiros, Vasileios Minadakis, Dingsheng Li, Haralambos Sarimveis
Publié dans: Toxicological Sciences, Numéro 200, 2024, Page(s) 31-46, ISSN 1096-6080
Éditeur: Oxford University Press
DOI: 10.1093/toxsci/kfae051

Evaluation of per- and polyfluoroalkyl substances (PFAS) toxic effects on the acute inflammatory response in the medicinal leech Hirudo verbana

Auteurs: A. Calisi, N. Baranzini, G. Marcolli, C. Bon, D. Rotondo, D. Gualandris, L. Pulze, A. Grimaldi, F. Dondero
Publié dans: Chemosphere, Numéro 366, 2024, Page(s) 143519, ISSN 0045-6535
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2024.143519

Degradation of organic pollutants combining plasma discharges generated within soil with TiO2 and ZnO catalysts: Comparative analysis, optimization and mechanisms

Auteurs: M. Hatzisymeon, M.K. Daletou, G. Rassias, C.A. Aggelopoulos
Publié dans: Separation and Purification Technology, Numéro Volume 320, 1 September 2023, 124119, 2023, Page(s) Article number 124119, ISSN 1383-5866
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.seppur.2023.124119

Mechanisms of Individual and Simultaneous Adsorption of Antibiotics and Dyes onto Halloysite Nanoclay and Regeneration of Saturated Adsorbent via Cold Plasma Bubbling

Auteurs: Stefania Giannoulia; Irene-Eva Triantaphyllidou; Athanasia G. Tekerlekopoulou; Christos A. Aggelopoulos
Publié dans: Nanomaterials, Numéro 13, 2023, Page(s) 341, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/nano13020341

A Review on Removal and Destruction of Per- and Polyfluoroalkyl Substances (PFAS) by Novel Membranes

Auteurs: Suman Das, Avner Ronen
Publié dans: Membranes, Numéro Membranes 2022, 12, 662, 2022, ISSN 2077-0375
Éditeur: Molecular Diversity Preservation International
DOI: 10.3390/membranes12070662

Exploration of cephalexin adsorption mechanisms onto bauxite and palygorskite and regeneration of spent adsorbents with cold plasma bubbling

Auteurs: S. Giannoulia, A. G. Tekerlekopoulou, C. A. Aggelopoulos
Publié dans: Applied Water Science, Numéro 14, 2024, ISSN 2190-5487
Éditeur: Springer Nature
DOI: 10.1007/s13201-024-02101-w

Key-study on plasma-induced degradation of cephalosporins in water: Process optimization, assessment of degradation mechanisms and residual toxicity

Auteurs: S. Meropoulis, S. Giannoulia, S. Skandalis, G. Rassias, C.A. Aggelopoulos
Publié dans: Separation and Purification Technology, Numéro Volume 2981, October 2022, 2022, Page(s) Article number 121639, ISSN 1383-5866
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.seppur.2022.121639

A Systematic Review of Deep Learning Methodologies Used in the Drug Discovery Process with Emphasis on In Vivo Validation

Auteurs: Nikoletta-Maria Koutroumpa, Konstantinos D. Papavasileiou, Anastasios G. Papadiamantis, Georgia Melagraki, Antreas Afantitis
Publié dans: International Journal of Molecular Sciences, Numéro Int. J. Mol. Sci. 2023, 24, 6573, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24076573

A novel, green, low-cost regeneration method for surface enhanced raman scattering (SERS) solid substrates based on nanosecond pulsed cold plasma technology

Auteurs: Z.G. Lada, G.A. Voyiatzis, C.A. Aggelopoulos
Publié dans: Surfaces and Interfaces, Numéro Volume 34, November 2022, 2022, Page(s) Article number 102330, ISSN 2468-0230
Éditeur: Elsevier
DOI: 10.1016/j.surfin.2022.102330

Reactive species and mechanisms of perfluorooctanoic acid (PFOA) degradation in water by cold plasma: The role of HV waveform, reactor design, water matrix and plasma gas

Auteurs: K. Papalexopoulou, X. Huang, A. Ronen, C.A. Aggelopoulos
Publié dans: Separation and Purification Technology, Numéro 342, 2024, Page(s) 126955, ISSN 1383-5866
Éditeur: Pergamon Press Ltd.
DOI: 10.5281/zenodo.14611262

Development of a Robust Read-Across Model for the Prediction of Biological Potency of Novel Peroxisome Proliferator-Activated Receptor Delta Agonists

Auteurs: Maria Antoniou, Konstantinos D. Papavasileiou, Georgia Melagraki, Francesco Dondero, Iseult Lynch, Antreas Afantitis
Publié dans: International Journal of Molecular Sciences, Numéro 25, 2024, Page(s) 5216, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25105216

Generic Method for the Detection of Short & Long Chain Pfas Extended to the Lowest Concentration Levels of Sers Capability

Auteurs: Zoi Lada, Georgios Mathioudakis, Amaia Soto Beobide, Konstantinos Andrikopoulos, George Voyiatzis
Publié dans: Chemosphere, Numéro 363, 2024, Page(s) 142916, ISSN 1879-1298
Éditeur: Elsevier
DOI: 10.2139/ssrn.4887145

Impact of Short-Chain Perfluoropropylene Oxide Acids on Biochemical and Behavioural Parameters in Eisenia fetida (Savigny, 1826)

Auteurs: Davide Rotondo, Davide Gualandris, Candida Lorusso, Albert Braeuning, Antonio Calisi, Francesco Dondero
Publié dans: Journal of Xenobiotics, Numéro 15, 2024, Page(s) 2, ISSN 2039-4713
Éditeur: MDPI
DOI: 10.3390/jox15010002

Book chapters (2)

Recent Advances in Computational Modeling of BACE1 Inhibitors as Anti-Alzheimer Agents

Auteurs: Konstantinos D. Papavasileiou, Francesco Dondero, Georgia Melagraki, Antreas Afantitis
Publié dans: Neuromethods, Computational Modeling of Drugs Against Alzheimer’s Disease, 2023, Page(s) 73-97
Éditeur: Springer US
DOI: 10.1007/978-1-0716-3311-3_3

Bioconversion of hazardous organic wastes using invertebrates

Auteurs: Angie M. Pedraza Torres, Juan C. Sanchez-Hernandez
Publié dans: Fate of Biological Contaminants During Recycling of Organic Wastes, Numéro Chapter Fifteen, 2023, Page(s) Pages 297-357, ISBN 978-0-323-95998-8
Éditeur: Elsevier
DOI: 10.1016/b978-0-323-95998-8.00007-8