Paving the way for High-throughput Organoid ENgineering using Integrated acoustiX

Project Information

PHOENIX

Grant agreement ID: 101043985

DOI

10.3030/101043985

EC signature date 25 July 2022

Start date 1 April 2023

End date 31 March 2028

Funded under

• European Research Council (ERC)

Total cost

€ 2 832 500,00

EU contribution

€ 2 832 500,00

Coordinated by

UPPSALA UNIVERSITET
Sweden

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

Round-robin testing of commercial two-photon polymerization 3D printers

Author(s): Federico Cantoni, Daniel Maher, Eugenia Bosler, Stefan Kühne, Laurent Barbe, Dirk Oberschmidt, Christophe Marquette, Rafael Taboryski, Maria Tenje, Ada-Ioana Bunea
Published in: Additive Manufacturing, Issue 76, 2023, ISSN 2214-8604
Publisher: Elsevier BV
DOI: 10.1016/J.ADDMA.2023.103761

A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels

Author(s): Federico Cantoni, Laurent Barbe, Hannah Pohlit, Maria Tenje
Published in: Advanced Materials Technologies, Issue 9, 2024, ISSN 2365-709X
Publisher: Wiley
DOI: 10.1002/ADMT.202300718

Universal Biomaterial-on-Chip: a versatile platform for evaluating cellular responses on diverse biomaterial substrates

Author(s): Abdul Raouf Atif, Morteza Aramesh, Sarah-Sophia Carter, Maria Tenje, Gemma Mestres
Published in: Journal of Materials Science: Materials in Medicine, Issue 35, 2024, ISSN 1573-4838
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/S10856-023-06771-X

A Microfluidic Platform for In Situ Studies of Bacteria Electroporation

Author(s): Ivan L. Volkov, Zahra Khaji, Magnus Johansson, Maria Tenje
Published in: Advanced Materials Technologies, Issue 10, 2025, ISSN 2365-709X
Publisher: Wiley
DOI: 10.1002/ADMT.202401177

Size-related variability of oxygen consumption rates in individual human hepatic cells

Author(s): Ermes Botte, Yuan Cui, Chiara Magliaro, Maria Tenje, Klaus Koren, Andrea Rinaldo, Roman Stocker, Lars Behrendt, Arti Ahluwalia
Published in: Lab on a Chip, Issue 24, 2024, ISSN 1473-0197
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4LC00204K

Technology platform for facile handling of 3D hydrogel cell culture scaffolds

Author(s): Hannah Pohlit, Jan Bohlin, Neeraj Katiyar, Jöns Hilborn, Maria Tenje
Published in: Scientific Reports, Issue 13, 2023, ISSN 2045-2322
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41598-023-39081-X

SlipO₂Chip – single-cell respiration under tuneable environments

Author(s): Yuan Cui, Milena De Albuquerque Moreira, Kristen E. Whalen, Laurent Barbe, Qian Shi, Klaus Koren, Maria Tenje, Lars Behrendt
Published in: Lab on a Chip, Issue 24, 2024, ISSN 1473-0197
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4LC00420E

Capacity and limitations of microfluidic flow to increase solute transport in three-dimensional cell cultures

Author(s): Willy V. Bonneuil, Neeraj Katiyar, Maria Tenje, Shervin Bagheri
Published in: Journal of The Royal Society Interface, Issue 22, 2025, ISSN 1742-5662
Publisher: The Royal Society
DOI: 10.1098/RSIF.2024.0463

Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system

Author(s): Mara Lucchetti, Gabriel Werr, Sofia Johansson, Laurent Barbe, Léa Grandmougin, Paul Wilmes, Maria Tenje
Published in: Microsystems & Nanoengineering, Issue 10, 2024, ISSN 2055-7434
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41378-023-00640-X

Dynamics of non-Newtonian agarose gel droplet formation in two-phase microfluidic systems

Author(s): Sagar N. Agnihotri, Pradipta Kr. Das, Femke Tolboom, Gabriel Werr, Estelle Palierse, Cecilia Persson, Maria Tenje
Published in: Physics of Fluids, Issue 37, 2025, ISSN 1070-6631
Publisher: AIP Publishing
DOI: 10.1063/5.0255319

Droplet microfluidics–based detection of rare antibiotic-resistant subpopulations in <i>Escherichia coli</i> from bloodstream infections

Author(s): Sagar N. Agnihotri, Nikos Fatsis-Kavalopoulos, Jonas Windhager, Maria Tenje, Dan I. Andersson
Published in: Science Advances, Issue 11, 2025, ISSN 2375-2548
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADV4558

Effects of the choice of the continuous phase in droplet microfluidics on internal particle manipulation with acoustophoresis

Author(s): Q. Shi, T. Baasch, Z. Liu, A. Fornell, G. Werr, L. Barbe, M. Tenje
Published in: The Journal of the Acoustical Society of America, Issue 157, 2025, ISSN 1520-8524
Publisher: Acoustical Society of America (ASA)
DOI: 10.1121/10.0036771

Conference proceedings (16)

Chemical gradient enabled spheroid-on-chip platform to study gradient-dependent modulation in cellular responses

Author(s): N. Katiyar, T.G. Bratt, A. Lehtola, M. Tenje.
Published in: EUROoCS-MPS 2025, 2025
Publisher: Kungliga biblioteket

Deformation dynamics of viscous droplets in standing acoustic wave

Author(s): P. Kr. Das, C. Meinhart, M. Tenje.
Published in: Acoustofluidics 2025, 2025
Publisher: Kungliga biblioteket

Plant-on-chip – towards cell-cell communication studies

Author(s): D. Valadorou, D. Kuang, L. Bogdziewiez, S. Stael, S. Verger, M. Tenje.
Published in: ICAR 2025, 2025
Publisher: Kungliga biblioteket

High-throughput oxygen consumption measurements in self-organizing 3D models under tuneable chemical environments

Author(s): M. Tenje, Y. Cui, S. Hakhverdyan, N.S.M. Luk, W. Michno, L. Behrendt
Published in: EUROoCS-MPS 2025, 2025
Publisher: Kungliga biblioteket

3D acoustic mixing via two-photon-printed microstructures

Author(s): N.S.M. Luk, M. Tenje.
Published in: Acoustofluidics 2025, 2025
Publisher: Kungliga Biblioteket

Towards robust bubble detection in diverse microphysiological systems by machine learning

Author(s): N. Koriakina, N. Sladoje, M. Tenje, S. Johansson
Published in: EUROoCS-MPS 2025, 2025
Publisher: Kungliga biblioteket

2D chemical gradient enabled spheroid-on-chip platform to study gradient-dependent modulation in cellular responses

Author(s): Neeraj Katiyar, Tora Godow Bratt, Laurent Barbe, Maria Tenje
Published in: EUROoCS 2024, 2024
Publisher: Kungliga Biblioteket

Acoustic fluid manipulation via two-photon-printed resonant microstructures

Author(s): Nicole S.M. Luk and Maria Tenje
Published in: NanoBioTech-Montreux 2024, 2024
Publisher: Kungliga Biblioteket

Investigating the impact of extracellular vesciles on the cytocompatibitliy of low-moduluse PMMA bone cement

Author(s): L. Hong, C. Persson, M. Nilsson, M. Tenje, W. Chrzanowski, N. Ferraz.
Published in: ScSB 2025, 2025

Development of a dual-flow 2-photon 3D printed hydrogel-based vessel-on-chip model

Author(s): A. Olivefors, S. Johansson, M. Tenje.
Published in: EUROoCS-MPS 2025, 2025
Publisher: Kungliga biblioteket

Numerical study of acoustic streaming in spherical droplets suspended in unconfined media, Micro Flow and Interfacial Phenomena 2025

Author(s): P.Kr. Das, C.D. Meinhart, M. Tenje.
Published in: µFIP 2025, 2025
Publisher: Kungliga biblioteket

Spatially resolved TEER suggests non-uniform differentiation in a Human Microbial Crosstalk gut-on-chip model

Author(s): Sofia Johansson, Mara Lucchetti, Gabriel Werr, Laurent Barbe, Paul Wilmes, Maria Tenje
Published in: EUROoCS 2024, 2024
Publisher: Kungliga Biblioteket

Temperature gradients inside acoustophoresis channels

Author(s): Gabriel Werr, Pradipta Kr. Das, Zahra Khaji, Maria Tenje
Published in: Acoustofluidics 2024, 2024
Publisher: Kungliga Biblioteket

A microfluidic gradient-on-chip platform for investigating biochemical gradient-driven cellular responses in 3D constructs

Author(s): N. Katiyar, T.G. Bratt, A. Lehtola, M. Tenje.
Published in: ESB 2025, 2025
Publisher: Kungliga biblioteket

Numerical study of acoustic streaming in spherical droplets suspended in unconfined media

Author(s): Pradipta Kr. Das, Carl D. Meinhart, Maria Tenje
Published in: Acoustofluidics 2024, 2024
Publisher: Kungliga Biblioteket

Design optimization of acoustic cavity traps for effective microparticle trapping

Author(s): Pradipta Kr. Das, Gabriel Werr, Maria Tenje
Published in: Acoustofluidics 2024, 2024
Publisher: Kungliga Biblioteket

Thesis and dissertations (1)

Acoustic manipulation in two-phase systems

Author(s): Qian Shi
Published in: 2025
Publisher: Uppsala University