Paving the way for High-throughput Organoid ENgineering using Integrated acoustiX

Informazioni relative al progetto

PHOENIX

ID dell’accordo di sovvenzione: 101043985

DOI

10.3030/101043985

Data della firma CE 25 Luglio 2022

Data di avvio 1 Aprile 2023

Data di completamento 31 Marzo 2028

Finanziato da

• European Research Council (ERC)

Costo totale

€ 2 832 500,00

Contributo UE

€ 2 832 500,00

Coordinato da

UPPSALA UNIVERSITET
Sweden

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (12)

Round-robin testing of commercial two-photon polymerization 3D printers

Autori: Federico Cantoni, Daniel Maher, Eugenia Bosler, Stefan Kühne, Laurent Barbe, Dirk Oberschmidt, Christophe Marquette, Rafael Taboryski, Maria Tenje, Ada-Ioana Bunea
Pubblicato in: Additive Manufacturing, Numero 76, 2023, ISSN 2214-8604
Editore: Elsevier BV
DOI: 10.1016/J.ADDMA.2023.103761

A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels

Autori: Federico Cantoni, Laurent Barbe, Hannah Pohlit, Maria Tenje
Pubblicato in: Advanced Materials Technologies, Numero 9, 2024, ISSN 2365-709X
Editore: Wiley
DOI: 10.1002/ADMT.202300718

Universal Biomaterial-on-Chip: a versatile platform for evaluating cellular responses on diverse biomaterial substrates

Autori: Abdul Raouf Atif, Morteza Aramesh, Sarah-Sophia Carter, Maria Tenje, Gemma Mestres
Pubblicato in: Journal of Materials Science: Materials in Medicine, Numero 35, 2024, ISSN 1573-4838
Editore: Springer Science and Business Media LLC
DOI: 10.1007/S10856-023-06771-X

A Microfluidic Platform for In Situ Studies of Bacteria Electroporation

Autori: Ivan L. Volkov, Zahra Khaji, Magnus Johansson, Maria Tenje
Pubblicato in: Advanced Materials Technologies, Numero 10, 2025, ISSN 2365-709X
Editore: Wiley
DOI: 10.1002/ADMT.202401177

Size-related variability of oxygen consumption rates in individual human hepatic cells

Autori: Ermes Botte, Yuan Cui, Chiara Magliaro, Maria Tenje, Klaus Koren, Andrea Rinaldo, Roman Stocker, Lars Behrendt, Arti Ahluwalia
Pubblicato in: Lab on a Chip, Numero 24, 2024, ISSN 1473-0197
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4LC00204K

Technology platform for facile handling of 3D hydrogel cell culture scaffolds

Autori: Hannah Pohlit, Jan Bohlin, Neeraj Katiyar, Jöns Hilborn, Maria Tenje
Pubblicato in: Scientific Reports, Numero 13, 2023, ISSN 2045-2322
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41598-023-39081-X

SlipO₂Chip – single-cell respiration under tuneable environments

Autori: Yuan Cui, Milena De Albuquerque Moreira, Kristen E. Whalen, Laurent Barbe, Qian Shi, Klaus Koren, Maria Tenje, Lars Behrendt
Pubblicato in: Lab on a Chip, Numero 24, 2024, ISSN 1473-0197
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4LC00420E

Capacity and limitations of microfluidic flow to increase solute transport in three-dimensional cell cultures

Autori: Willy V. Bonneuil, Neeraj Katiyar, Maria Tenje, Shervin Bagheri
Pubblicato in: Journal of The Royal Society Interface, Numero 22, 2025, ISSN 1742-5662
Editore: The Royal Society
DOI: 10.1098/RSIF.2024.0463

Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system

Autori: Mara Lucchetti, Gabriel Werr, Sofia Johansson, Laurent Barbe, Léa Grandmougin, Paul Wilmes, Maria Tenje
Pubblicato in: Microsystems & Nanoengineering, Numero 10, 2024, ISSN 2055-7434
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41378-023-00640-X

Dynamics of non-Newtonian agarose gel droplet formation in two-phase microfluidic systems

Autori: Sagar N. Agnihotri, Pradipta Kr. Das, Femke Tolboom, Gabriel Werr, Estelle Palierse, Cecilia Persson, Maria Tenje
Pubblicato in: Physics of Fluids, Numero 37, 2025, ISSN 1070-6631
Editore: AIP Publishing
DOI: 10.1063/5.0255319

Droplet microfluidics–based detection of rare antibiotic-resistant subpopulations in <i>Escherichia coli</i> from bloodstream infections

Autori: Sagar N. Agnihotri, Nikos Fatsis-Kavalopoulos, Jonas Windhager, Maria Tenje, Dan I. Andersson
Pubblicato in: Science Advances, Numero 11, 2025, ISSN 2375-2548
Editore: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADV4558

Effects of the choice of the continuous phase in droplet microfluidics on internal particle manipulation with acoustophoresis

Autori: Q. Shi, T. Baasch, Z. Liu, A. Fornell, G. Werr, L. Barbe, M. Tenje
Pubblicato in: The Journal of the Acoustical Society of America, Numero 157, 2025, ISSN 1520-8524
Editore: Acoustical Society of America (ASA)
DOI: 10.1121/10.0036771

Conference proceedings (16)

Chemical gradient enabled spheroid-on-chip platform to study gradient-dependent modulation in cellular responses

Autori: N. Katiyar, T.G. Bratt, A. Lehtola, M. Tenje.
Pubblicato in: EUROoCS-MPS 2025, 2025
Editore: Kungliga biblioteket

Deformation dynamics of viscous droplets in standing acoustic wave

Autori: P. Kr. Das, C. Meinhart, M. Tenje.
Pubblicato in: Acoustofluidics 2025, 2025
Editore: Kungliga biblioteket

Plant-on-chip – towards cell-cell communication studies

Autori: D. Valadorou, D. Kuang, L. Bogdziewiez, S. Stael, S. Verger, M. Tenje.
Pubblicato in: ICAR 2025, 2025
Editore: Kungliga biblioteket

High-throughput oxygen consumption measurements in self-organizing 3D models under tuneable chemical environments

Autori: M. Tenje, Y. Cui, S. Hakhverdyan, N.S.M. Luk, W. Michno, L. Behrendt
Pubblicato in: EUROoCS-MPS 2025, 2025
Editore: Kungliga biblioteket

3D acoustic mixing via two-photon-printed microstructures

Autori: N.S.M. Luk, M. Tenje.
Pubblicato in: Acoustofluidics 2025, 2025
Editore: Kungliga Biblioteket

Towards robust bubble detection in diverse microphysiological systems by machine learning

Autori: N. Koriakina, N. Sladoje, M. Tenje, S. Johansson
Pubblicato in: EUROoCS-MPS 2025, 2025
Editore: Kungliga biblioteket

2D chemical gradient enabled spheroid-on-chip platform to study gradient-dependent modulation in cellular responses

Autori: Neeraj Katiyar, Tora Godow Bratt, Laurent Barbe, Maria Tenje
Pubblicato in: EUROoCS 2024, 2024
Editore: Kungliga Biblioteket

Acoustic fluid manipulation via two-photon-printed resonant microstructures

Autori: Nicole S.M. Luk and Maria Tenje
Pubblicato in: NanoBioTech-Montreux 2024, 2024
Editore: Kungliga Biblioteket

Investigating the impact of extracellular vesciles on the cytocompatibitliy of low-moduluse PMMA bone cement

Autori: L. Hong, C. Persson, M. Nilsson, M. Tenje, W. Chrzanowski, N. Ferraz.
Pubblicato in: ScSB 2025, 2025

Development of a dual-flow 2-photon 3D printed hydrogel-based vessel-on-chip model

Autori: A. Olivefors, S. Johansson, M. Tenje.
Pubblicato in: EUROoCS-MPS 2025, 2025
Editore: Kungliga biblioteket

Numerical study of acoustic streaming in spherical droplets suspended in unconfined media, Micro Flow and Interfacial Phenomena 2025

Autori: P.Kr. Das, C.D. Meinhart, M. Tenje.
Pubblicato in: µFIP 2025, 2025
Editore: Kungliga biblioteket

Spatially resolved TEER suggests non-uniform differentiation in a Human Microbial Crosstalk gut-on-chip model

Autori: Sofia Johansson, Mara Lucchetti, Gabriel Werr, Laurent Barbe, Paul Wilmes, Maria Tenje
Pubblicato in: EUROoCS 2024, 2024
Editore: Kungliga Biblioteket

Temperature gradients inside acoustophoresis channels

Autori: Gabriel Werr, Pradipta Kr. Das, Zahra Khaji, Maria Tenje
Pubblicato in: Acoustofluidics 2024, 2024
Editore: Kungliga Biblioteket

A microfluidic gradient-on-chip platform for investigating biochemical gradient-driven cellular responses in 3D constructs

Autori: N. Katiyar, T.G. Bratt, A. Lehtola, M. Tenje.
Pubblicato in: ESB 2025, 2025
Editore: Kungliga biblioteket

Numerical study of acoustic streaming in spherical droplets suspended in unconfined media

Autori: Pradipta Kr. Das, Carl D. Meinhart, Maria Tenje
Pubblicato in: Acoustofluidics 2024, 2024
Editore: Kungliga Biblioteket

Design optimization of acoustic cavity traps for effective microparticle trapping

Autori: Pradipta Kr. Das, Gabriel Werr, Maria Tenje
Pubblicato in: Acoustofluidics 2024, 2024
Editore: Kungliga Biblioteket

Thesis and dissertations (1)

Acoustic manipulation in two-phase systems

Autori: Qian Shi
Pubblicato in: 2025
Editore: Uppsala University