Paving the way for High-throughput Organoid ENgineering using Integrated acoustiX

Información del proyecto

PHOENIX

Identificador del acuerdo de subvención: 101043985

DOI

10.3030/101043985

Fecha de la firma de la CE 25 Julio 2022

Fecha de inicio 1 Abril 2023

Fecha de finalización 31 Marzo 2028

Financiado con arreglo a

• European Research Council (ERC)

Coste total

€ 2 832 500,00

Aportación de la UE

€ 2 832 500,00

Coordinado por

UPPSALA UNIVERSITET
Sweden

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (12)

Round-robin testing of commercial two-photon polymerization 3D printers

Autores: Federico Cantoni, Daniel Maher, Eugenia Bosler, Stefan Kühne, Laurent Barbe, Dirk Oberschmidt, Christophe Marquette, Rafael Taboryski, Maria Tenje, Ada-Ioana Bunea
Publicado en: Additive Manufacturing, Edición 76, 2023, ISSN 2214-8604
Editor: Elsevier BV
DOI: 10.1016/J.ADDMA.2023.103761

A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels

Autores: Federico Cantoni, Laurent Barbe, Hannah Pohlit, Maria Tenje
Publicado en: Advanced Materials Technologies, Edición 9, 2024, ISSN 2365-709X
Editor: Wiley
DOI: 10.1002/ADMT.202300718

Universal Biomaterial-on-Chip: a versatile platform for evaluating cellular responses on diverse biomaterial substrates

Autores: Abdul Raouf Atif, Morteza Aramesh, Sarah-Sophia Carter, Maria Tenje, Gemma Mestres
Publicado en: Journal of Materials Science: Materials in Medicine, Edición 35, 2024, ISSN 1573-4838
Editor: Springer Science and Business Media LLC
DOI: 10.1007/S10856-023-06771-X

A Microfluidic Platform for In Situ Studies of Bacteria Electroporation

Autores: Ivan L. Volkov, Zahra Khaji, Magnus Johansson, Maria Tenje
Publicado en: Advanced Materials Technologies, Edición 10, 2025, ISSN 2365-709X
Editor: Wiley
DOI: 10.1002/ADMT.202401177

Size-related variability of oxygen consumption rates in individual human hepatic cells

Autores: Ermes Botte, Yuan Cui, Chiara Magliaro, Maria Tenje, Klaus Koren, Andrea Rinaldo, Roman Stocker, Lars Behrendt, Arti Ahluwalia
Publicado en: Lab on a Chip, Edición 24, 2024, ISSN 1473-0197
Editor: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4LC00204K

Technology platform for facile handling of 3D hydrogel cell culture scaffolds

Autores: Hannah Pohlit, Jan Bohlin, Neeraj Katiyar, Jöns Hilborn, Maria Tenje
Publicado en: Scientific Reports, Edición 13, 2023, ISSN 2045-2322
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41598-023-39081-X

SlipO₂Chip – single-cell respiration under tuneable environments

Autores: Yuan Cui, Milena De Albuquerque Moreira, Kristen E. Whalen, Laurent Barbe, Qian Shi, Klaus Koren, Maria Tenje, Lars Behrendt
Publicado en: Lab on a Chip, Edición 24, 2024, ISSN 1473-0197
Editor: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4LC00420E

Capacity and limitations of microfluidic flow to increase solute transport in three-dimensional cell cultures

Autores: Willy V. Bonneuil, Neeraj Katiyar, Maria Tenje, Shervin Bagheri
Publicado en: Journal of The Royal Society Interface, Edición 22, 2025, ISSN 1742-5662
Editor: The Royal Society
DOI: 10.1098/RSIF.2024.0463

Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system

Autores: Mara Lucchetti, Gabriel Werr, Sofia Johansson, Laurent Barbe, Léa Grandmougin, Paul Wilmes, Maria Tenje
Publicado en: Microsystems & Nanoengineering, Edición 10, 2024, ISSN 2055-7434
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41378-023-00640-X

Dynamics of non-Newtonian agarose gel droplet formation in two-phase microfluidic systems

Autores: Sagar N. Agnihotri, Pradipta Kr. Das, Femke Tolboom, Gabriel Werr, Estelle Palierse, Cecilia Persson, Maria Tenje
Publicado en: Physics of Fluids, Edición 37, 2025, ISSN 1070-6631
Editor: AIP Publishing
DOI: 10.1063/5.0255319

Droplet microfluidics–based detection of rare antibiotic-resistant subpopulations in <i>Escherichia coli</i> from bloodstream infections

Autores: Sagar N. Agnihotri, Nikos Fatsis-Kavalopoulos, Jonas Windhager, Maria Tenje, Dan I. Andersson
Publicado en: Science Advances, Edición 11, 2025, ISSN 2375-2548
Editor: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADV4558

Effects of the choice of the continuous phase in droplet microfluidics on internal particle manipulation with acoustophoresis

Autores: Q. Shi, T. Baasch, Z. Liu, A. Fornell, G. Werr, L. Barbe, M. Tenje
Publicado en: The Journal of the Acoustical Society of America, Edición 157, 2025, ISSN 1520-8524
Editor: Acoustical Society of America (ASA)
DOI: 10.1121/10.0036771

Conference proceedings (16)

Chemical gradient enabled spheroid-on-chip platform to study gradient-dependent modulation in cellular responses

Autores: N. Katiyar, T.G. Bratt, A. Lehtola, M. Tenje.
Publicado en: EUROoCS-MPS 2025, 2025
Editor: Kungliga biblioteket

Deformation dynamics of viscous droplets in standing acoustic wave

Autores: P. Kr. Das, C. Meinhart, M. Tenje.
Publicado en: Acoustofluidics 2025, 2025
Editor: Kungliga biblioteket

Plant-on-chip – towards cell-cell communication studies

Autores: D. Valadorou, D. Kuang, L. Bogdziewiez, S. Stael, S. Verger, M. Tenje.
Publicado en: ICAR 2025, 2025
Editor: Kungliga biblioteket

High-throughput oxygen consumption measurements in self-organizing 3D models under tuneable chemical environments

Autores: M. Tenje, Y. Cui, S. Hakhverdyan, N.S.M. Luk, W. Michno, L. Behrendt
Publicado en: EUROoCS-MPS 2025, 2025
Editor: Kungliga biblioteket

3D acoustic mixing via two-photon-printed microstructures

Autores: N.S.M. Luk, M. Tenje.
Publicado en: Acoustofluidics 2025, 2025
Editor: Kungliga Biblioteket

Towards robust bubble detection in diverse microphysiological systems by machine learning

Autores: N. Koriakina, N. Sladoje, M. Tenje, S. Johansson
Publicado en: EUROoCS-MPS 2025, 2025
Editor: Kungliga biblioteket

2D chemical gradient enabled spheroid-on-chip platform to study gradient-dependent modulation in cellular responses

Autores: Neeraj Katiyar, Tora Godow Bratt, Laurent Barbe, Maria Tenje
Publicado en: EUROoCS 2024, 2024
Editor: Kungliga Biblioteket

Acoustic fluid manipulation via two-photon-printed resonant microstructures

Autores: Nicole S.M. Luk and Maria Tenje
Publicado en: NanoBioTech-Montreux 2024, 2024
Editor: Kungliga Biblioteket

Investigating the impact of extracellular vesciles on the cytocompatibitliy of low-moduluse PMMA bone cement

Autores: L. Hong, C. Persson, M. Nilsson, M. Tenje, W. Chrzanowski, N. Ferraz.
Publicado en: ScSB 2025, 2025

Development of a dual-flow 2-photon 3D printed hydrogel-based vessel-on-chip model

Autores: A. Olivefors, S. Johansson, M. Tenje.
Publicado en: EUROoCS-MPS 2025, 2025
Editor: Kungliga biblioteket

Numerical study of acoustic streaming in spherical droplets suspended in unconfined media, Micro Flow and Interfacial Phenomena 2025

Autores: P.Kr. Das, C.D. Meinhart, M. Tenje.
Publicado en: µFIP 2025, 2025
Editor: Kungliga biblioteket

Spatially resolved TEER suggests non-uniform differentiation in a Human Microbial Crosstalk gut-on-chip model

Autores: Sofia Johansson, Mara Lucchetti, Gabriel Werr, Laurent Barbe, Paul Wilmes, Maria Tenje
Publicado en: EUROoCS 2024, 2024
Editor: Kungliga Biblioteket

Temperature gradients inside acoustophoresis channels

Autores: Gabriel Werr, Pradipta Kr. Das, Zahra Khaji, Maria Tenje
Publicado en: Acoustofluidics 2024, 2024
Editor: Kungliga Biblioteket

A microfluidic gradient-on-chip platform for investigating biochemical gradient-driven cellular responses in 3D constructs

Autores: N. Katiyar, T.G. Bratt, A. Lehtola, M. Tenje.
Publicado en: ESB 2025, 2025
Editor: Kungliga biblioteket

Numerical study of acoustic streaming in spherical droplets suspended in unconfined media

Autores: Pradipta Kr. Das, Carl D. Meinhart, Maria Tenje
Publicado en: Acoustofluidics 2024, 2024
Editor: Kungliga Biblioteket

Design optimization of acoustic cavity traps for effective microparticle trapping

Autores: Pradipta Kr. Das, Gabriel Werr, Maria Tenje
Publicado en: Acoustofluidics 2024, 2024
Editor: Kungliga Biblioteket

Thesis and dissertations (1)

Acoustic manipulation in two-phase systems

Autores: Qian Shi
Publicado en: 2025
Editor: Uppsala University