Continuously renewable, CO2-neutral, clean, affordable and modern energy for the benefit of all people is at the core of SDG7. In parallel, the EU Renewable Energy Directive and the REPowerEU plan set ambitious targets for the share of renewables in the EU energy mix. Geothermal energy, defined as the thermal energy stored in the Earth, is a key candidate to provide secure, low-carbon baseload heat and power. Yet, today’s installed geothermal capacity exploits less than a tiny fraction of the global resource, mainly because deep wells in hard rocks remain expensive and risky to drill with conventional rotary technologies. Current deep geothermal technologies are constrained by depth (typically 4–5 km), long drilling times, complex drilling fluids, multiple casing and cementing stages and significant non-productive time. To overcome these limits and improve the techno-economic performance of deep systems, DeepU focuses on demonstrating, at laboratory scale, a U-shaped closed-loop system physically isolated from the surrounding environment. The project combines a high-power laser with a cryogenic gaseous flushing medium (liquid nitrogen), an innovative multi-pipe drill string and dedicated processing heads to create a heat exchanger consisting of two vertical and one horizontal section (U-shape). Experiments and modelling carried out in the different work packages show that, under appropriate conditions, laser and cryogenic gas can jointly remove, melt and vitrify rock, forming a glazed layer on the borehole wall with low permeability and good mechanical integrity. This would enable an underground closed-loop system to be operated immediately after drilling, without conventional casing, and could also support favourable gravity-driven circulation during exploitation. If successfully scaled up beyond the laboratory, the DeepU technology could contribute to the realisation of ultra-deep geothermal heat exchangers at depths greater than 4 km, making “geothermal anywhere” a realistic option and supporting EU climate-neutrality and energy-transition objectives