Practical oxyfunctionalisation biocatalysts by engineering monooxygenases into peroxyzymes.

Información del proyecto

PeroxyZyme

Identificador del acuerdo de subvención: 101054658

DOI

10.3030/101054658

Fecha de la firma de la CE 1 Junio 2022

Fecha de inicio 1 Agosto 2022

Fecha de finalización 31 Julio 2027

Financiado con arreglo a

• European Research Council (ERC)

Coste total

€ 2 500 000,00

Aportación de la UE

€ 2 500 000,00

Coordinado por

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected processed or generated by the project It is a document describing what data will be collected processed or generated and following what methodology and standards whether and how this data will be shared andor made open and how it will be curated and preserved

Publicaciones

Peer reviewed articles (18)

A solvent-free synthesis of (thio)ester derivatives using FeCl3 as a heterogeneous catalyst

Autores: Sabry H.H. Younes, F. Hollmann
Publicado en: Tetrahedron Letters, Edición 123, 2024, ISSN 0040-4039
Editor: Elsevier BV
DOI: 10.1016/j.tetlet.2023.154524

Combining biocatalytic oxyfunctionalisation and organocatalytic aldol reaction to access chiral β-hydroxy ketones

Autores: Yutong Wang, Chiara Domestici, Niklas Teetz, Dirk Holtmann, Miguel Alcalde, Mengfan Wang, Wei Qi, Wuyuan Zhang, Frank Hollmann
Publicado en: Molecular Catalysis, Edición 569, 2024, ISSN 2468-8231
Editor: Elsevier BV
DOI: 10.1016/j.mcat.2024.114515

Formate‐Mediated Electroenzymatic Synthesis via Biological Cofactor NADH

Autores: Chuanjun Wang, Wenjin Dong, Pengye Zhang, Yaya Ma, Zhiwei Han, Yutai Zou, Wenshuo Wang, Hao Li, Frank Hollmann, Jian Liu
Publicado en: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editor: Wiley
DOI: 10.1002/anie.202408756

Selective Peroxygenase‐Catalysed Oxidation of Toluene Derivates to Benzaldehydes

Autores: Yutong Wang, Niklas Teetz, Dirk Holtmann, Miguel Alcalde, Jacob M. A. van Hengst, Xiaoxiao Liu, Mengfan Wang, Wei Qi, Wuyuan Zhang, Frank Hollmann
Publicado en: ChemCatChem, Edición 15, 2023, ISSN 1867-3880
Editor: Wiley
DOI: 10.1002/cctc.202300645

Photobiocatalysis: More than just an interesting lab curiosity?

Autores: Yunjian Ma, Yutong Wang, Bin Wu, Jianle Zhou, Shunong Yang, Fangyu Zhang, Keyu Luo, Yonghua Wang, Frank Hollmann
Publicado en: Chem Catalysis, 2024, ISSN 2667-1093
Editor: Elsevier BV
DOI: 10.1016/j.checat.2024.101077

Selective oxyfunctionalisation reactions catalysed by P450 monooxygenases and peroxygenases – A bright future for sustainable chemical synthesis

Autores: X. Xu, T. Hilberath, F. Hollmann
Publicado en: Current Opinion in Green and Sustainable Chemistry, Edición 39, 2023, ISSN 2452-2236
Editor: Elsevier BV
DOI: 10.1016/j.cogsc.2022.100745

Biosynthesis of cyclic ketones by a H2O2 self-sufficient cascade reaction

Autores: Bin Wu, Xiangyun Wang, Bo Yang, Yunjian Ma, Frank Hollmann, Yonghua Wang
Publicado en: Molecular Catalysis, Edición 547, 2023, ISSN 2468-8231
Editor: Elsevier BV
DOI: 10.1016/j.mcat.2023.113396

Peroxygenase‐Catalysed Sulfoxidations in Non‐Aqueous Media

Autores: Huanhuan Li, Qianqian Shen, Xiaoying Zhou, Peigao Duan, Frank Hollmann, Yawen Huang, Wuyuan Zhang
Publicado en: ChemSusChem, Edición 17, 2024, ISSN 1864-5631
Editor: Wiley
DOI: 10.1002/cssc.202301321

Oxidation of Cyclohexane to Cyclohexanol/Cyclohexanone Using Sol‐Gel‐Encapsulated Unspecific Peroxygenase from <i>Agrocybe aegerita</i>

Autores: Yinqi Wu, Frank Hollmann, Musa M. Musa
Publicado en: ChemistryOpen, 2024, ISSN 2191-1363
Editor: Wiley
DOI: 10.1002/open.202400152

Structure-Based Redesign of a Methanol Oxidase into an “Aryl Alcohol Oxidase” for Enzymatic Synthesis of Aromatic Flavor Compounds

Autores: Bin Wu, Shiyu Wang, Yunjian Ma, Shuguang Yuan, Frank Hollmann, Yonghua Wang
Publicado en: Journal of Agricultural and Food Chemistry, Edición 71, 2023, ISSN 0021-8561
Editor: American Chemical Society (ACS)
DOI: 10.1021/acs.jafc.3c01069

Selective Peroxygenase‐Catalysed Oxidation of Phenols to Hydroquinones

Autores: Hugo Brasselet, Fabian Schmitz, Katja Koschorreck, Vlada B. Urlacher, Frank Hollmann, Thomas Hilberath
Publicado en: Advanced Synthesis &amp; Catalysis, 2024, ISSN 1615-4150
Editor: Wiley
DOI: 10.1002/adsc.202400872

Mirror, mirror on the wall, which is the greenest of them all? A critical comparison of chemo- and biocatalytic oxyfunctionalisation reactions

Autores: Yinqi Wu, Caroline E. Paul, Frank Hollmann
Publicado en: Green Carbon, Edición 1, 2024, ISSN 2950-1555
Editor: Elsevier BV
DOI: 10.1016/j.greenca.2023.10.004

Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane

Autores: Thomas Hilberath, Remco van Oosten, Juliet Victoria, Hugo Brasselet, Miguel Alcalde, John M. Woodley, Frank Hollmann
Publicado en: Organic Process Research &amp; Development, Edición 27, 2023, ISSN 1083-6160
Editor: American Chemical Society (ACS)
DOI: 10.1021/acs.oprd.3c00135

Hybrid Organometallic and Enzymatic Tandem Catalysis for Oxyfunctionalisation Reactions

Autores: Chiara Domestici, Yinqi Wu, Thomas Hilberath, Miguel Alcalde, Frank Hollmann, Alceo Macchioni
Publicado en: ChemCatChem, Edición 15, 2023, ISSN 1867-3880
Editor: Wiley
DOI: 10.1002/cctc.202201623

Synthesis of Enantiopure Vicinal Halohydrins Using a Sequence of Haloperoxidase and Lipase

Autores: Elisa De Marchi, Thomas Hilberath, Claudio Zippilli, Ron Wever, Raffaele Saladino, Frank Hollmann, Lorenzo Botta
Publicado en: Advanced Synthesis &amp; Catalysis, Edición 366, 2024, ISSN 1615-4150
Editor: Wiley
DOI: 10.1002/adsc.202400516

Peroxygenase‐Promoted Enzymatic Cascades for the Valorisation of Fatty Acids

Autores: Yinqi Wu, Caroline E. Paul, Thomas Hilberath, Ewald P. J. Jongkind, Wuyuan Zhang, Miguel Alcalde, Frank Hollmann
Publicado en: ChemCatChem, Edición 15, 2023, ISSN 1867-3880
Editor: Wiley
DOI: 10.1002/cctc.202300411

Learning from Protein Engineering by Deconvolution of Multi‐Mutational Variants

Autores: Frank Hollmann, Joaquin Sanchis, Manfred T. Reetz
Publicado en: Angewandte Chemie International Edition, Edición 63, 2024, ISSN 1433-7851
Editor: Wiley
DOI: 10.1002/anie.202404880

Peroxygenase‐Catalysed Selective Oxidation of Silanes to Silanols

Autores: Xiaomin Xu, Jacob M. A. van Hengst, Yejia Mao, Mireia Martinez, Sergi Roda, Martin Floor, Victor Guallar, Caroline E. Paul, Miguel Alcalde, Frank Hollmann
Publicado en: Angewandte Chemie International Edition, Edición 62, 2024, ISSN 1433-7851
Editor: Wiley
DOI: 10.1002/anie.202302844