Practical oxyfunctionalisation biocatalysts by engineering monooxygenases into peroxyzymes.

Informazioni relative al progetto

PeroxyZyme

ID dell’accordo di sovvenzione: 101054658

DOI

10.3030/101054658

Data della firma CE 1 Giugno 2022

Data di avvio 1 Agosto 2022

Data di completamento 31 Luglio 2027

Finanziato da

• European Research Council (ERC)

Costo totale

€ 2 500 000,00

Contributo UE

€ 2 500 000,00

Coordinato da

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected processed or generated by the project It is a document describing what data will be collected processed or generated and following what methodology and standards whether and how this data will be shared andor made open and how it will be curated and preserved

Pubblicazioni

Peer reviewed articles (18)

A solvent-free synthesis of (thio)ester derivatives using FeCl3 as a heterogeneous catalyst

Autori: Sabry H.H. Younes, F. Hollmann
Pubblicato in: Tetrahedron Letters, Numero 123, 2024, ISSN 0040-4039
Editore: Elsevier BV
DOI: 10.1016/j.tetlet.2023.154524

Combining biocatalytic oxyfunctionalisation and organocatalytic aldol reaction to access chiral β-hydroxy ketones

Autori: Yutong Wang, Chiara Domestici, Niklas Teetz, Dirk Holtmann, Miguel Alcalde, Mengfan Wang, Wei Qi, Wuyuan Zhang, Frank Hollmann
Pubblicato in: Molecular Catalysis, Numero 569, 2024, ISSN 2468-8231
Editore: Elsevier BV
DOI: 10.1016/j.mcat.2024.114515

Formate‐Mediated Electroenzymatic Synthesis via Biological Cofactor NADH

Autori: Chuanjun Wang, Wenjin Dong, Pengye Zhang, Yaya Ma, Zhiwei Han, Yutai Zou, Wenshuo Wang, Hao Li, Frank Hollmann, Jian Liu
Pubblicato in: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editore: Wiley
DOI: 10.1002/anie.202408756

Selective Peroxygenase‐Catalysed Oxidation of Toluene Derivates to Benzaldehydes

Autori: Yutong Wang, Niklas Teetz, Dirk Holtmann, Miguel Alcalde, Jacob M. A. van Hengst, Xiaoxiao Liu, Mengfan Wang, Wei Qi, Wuyuan Zhang, Frank Hollmann
Pubblicato in: ChemCatChem, Numero 15, 2023, ISSN 1867-3880
Editore: Wiley
DOI: 10.1002/cctc.202300645

Photobiocatalysis: More than just an interesting lab curiosity?

Autori: Yunjian Ma, Yutong Wang, Bin Wu, Jianle Zhou, Shunong Yang, Fangyu Zhang, Keyu Luo, Yonghua Wang, Frank Hollmann
Pubblicato in: Chem Catalysis, 2024, ISSN 2667-1093
Editore: Elsevier BV
DOI: 10.1016/j.checat.2024.101077

Selective oxyfunctionalisation reactions catalysed by P450 monooxygenases and peroxygenases – A bright future for sustainable chemical synthesis

Autori: X. Xu, T. Hilberath, F. Hollmann
Pubblicato in: Current Opinion in Green and Sustainable Chemistry, Numero 39, 2023, ISSN 2452-2236
Editore: Elsevier BV
DOI: 10.1016/j.cogsc.2022.100745

Biosynthesis of cyclic ketones by a H2O2 self-sufficient cascade reaction

Autori: Bin Wu, Xiangyun Wang, Bo Yang, Yunjian Ma, Frank Hollmann, Yonghua Wang
Pubblicato in: Molecular Catalysis, Numero 547, 2023, ISSN 2468-8231
Editore: Elsevier BV
DOI: 10.1016/j.mcat.2023.113396

Peroxygenase‐Catalysed Sulfoxidations in Non‐Aqueous Media

Autori: Huanhuan Li, Qianqian Shen, Xiaoying Zhou, Peigao Duan, Frank Hollmann, Yawen Huang, Wuyuan Zhang
Pubblicato in: ChemSusChem, Numero 17, 2024, ISSN 1864-5631
Editore: Wiley
DOI: 10.1002/cssc.202301321

Oxidation of Cyclohexane to Cyclohexanol/Cyclohexanone Using Sol‐Gel‐Encapsulated Unspecific Peroxygenase from <i>Agrocybe aegerita</i>

Autori: Yinqi Wu, Frank Hollmann, Musa M. Musa
Pubblicato in: ChemistryOpen, 2024, ISSN 2191-1363
Editore: Wiley
DOI: 10.1002/open.202400152

Structure-Based Redesign of a Methanol Oxidase into an “Aryl Alcohol Oxidase” for Enzymatic Synthesis of Aromatic Flavor Compounds

Autori: Bin Wu, Shiyu Wang, Yunjian Ma, Shuguang Yuan, Frank Hollmann, Yonghua Wang
Pubblicato in: Journal of Agricultural and Food Chemistry, Numero 71, 2023, ISSN 0021-8561
Editore: American Chemical Society (ACS)
DOI: 10.1021/acs.jafc.3c01069

Selective Peroxygenase‐Catalysed Oxidation of Phenols to Hydroquinones

Autori: Hugo Brasselet, Fabian Schmitz, Katja Koschorreck, Vlada B. Urlacher, Frank Hollmann, Thomas Hilberath
Pubblicato in: Advanced Synthesis &amp; Catalysis, 2024, ISSN 1615-4150
Editore: Wiley
DOI: 10.1002/adsc.202400872

Mirror, mirror on the wall, which is the greenest of them all? A critical comparison of chemo- and biocatalytic oxyfunctionalisation reactions

Autori: Yinqi Wu, Caroline E. Paul, Frank Hollmann
Pubblicato in: Green Carbon, Numero 1, 2024, ISSN 2950-1555
Editore: Elsevier BV
DOI: 10.1016/j.greenca.2023.10.004

Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane

Autori: Thomas Hilberath, Remco van Oosten, Juliet Victoria, Hugo Brasselet, Miguel Alcalde, John M. Woodley, Frank Hollmann
Pubblicato in: Organic Process Research &amp; Development, Numero 27, 2023, ISSN 1083-6160
Editore: American Chemical Society (ACS)
DOI: 10.1021/acs.oprd.3c00135

Hybrid Organometallic and Enzymatic Tandem Catalysis for Oxyfunctionalisation Reactions

Autori: Chiara Domestici, Yinqi Wu, Thomas Hilberath, Miguel Alcalde, Frank Hollmann, Alceo Macchioni
Pubblicato in: ChemCatChem, Numero 15, 2023, ISSN 1867-3880
Editore: Wiley
DOI: 10.1002/cctc.202201623

Synthesis of Enantiopure Vicinal Halohydrins Using a Sequence of Haloperoxidase and Lipase

Autori: Elisa De Marchi, Thomas Hilberath, Claudio Zippilli, Ron Wever, Raffaele Saladino, Frank Hollmann, Lorenzo Botta
Pubblicato in: Advanced Synthesis &amp; Catalysis, Numero 366, 2024, ISSN 1615-4150
Editore: Wiley
DOI: 10.1002/adsc.202400516

Peroxygenase‐Promoted Enzymatic Cascades for the Valorisation of Fatty Acids

Autori: Yinqi Wu, Caroline E. Paul, Thomas Hilberath, Ewald P. J. Jongkind, Wuyuan Zhang, Miguel Alcalde, Frank Hollmann
Pubblicato in: ChemCatChem, Numero 15, 2023, ISSN 1867-3880
Editore: Wiley
DOI: 10.1002/cctc.202300411

Learning from Protein Engineering by Deconvolution of Multi‐Mutational Variants

Autori: Frank Hollmann, Joaquin Sanchis, Manfred T. Reetz
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2024, ISSN 1433-7851
Editore: Wiley
DOI: 10.1002/anie.202404880

Peroxygenase‐Catalysed Selective Oxidation of Silanes to Silanols

Autori: Xiaomin Xu, Jacob M. A. van Hengst, Yejia Mao, Mireia Martinez, Sergi Roda, Martin Floor, Victor Guallar, Caroline E. Paul, Miguel Alcalde, Frank Hollmann
Pubblicato in: Angewandte Chemie International Edition, Numero 62, 2024, ISSN 1433-7851
Editore: Wiley
DOI: 10.1002/anie.202302844