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Clinical Validation of an AI-based approach to improve the shared decision-making process and outcomes in Breast Cancer Patients proposed for Locoregional treatment

Descrizione del progetto

Prevedere i risultati estetici dell’intervento chirurgico del carcinoma mammario

Il trattamento del tumore al seno spesso implica un intervento chirurgico che varia a seconda del singolo tumore, della dimensione e della forma dei seni o di desideri personali. La chirurgia conservativa del seno e la mastectomia con o senza la ricostruzione o la rimozione dei linfonodi figurano tra le opzioni disponibili. Inoltre, è possibile eseguire la radioterapia per ottimizzare il controllo locoregionale. Ciononostante, attualmente non esiste alcun modo di ricapitolare il risultato estetico a seguito di trattamenti locoregionali del carcinoma mammario. Il progetto CINDERELLA, finanziato dall’UE, propone di realizzare un’applicazione di facile utilizzo basata sull’IA che impiega una banca dati clinica e abbina foto e dati biometrici al fine di creare immagini per simulare il risultato dell’operazione chirurgica. La piattaforma denominata CINDERELLA APProach potenzierà il ruolo delle pazienti nel processo decisionale clinico.

Obiettivo

Breast cancer is the most commonly diagnosed cancer, with an estimated 2.3 million new cases per year globally. Approximately 90% of these patients will undergo breast surgery with/without radiation (locoregional treatment). Different surgical techniques can be offered to the patient, each leading to completely different aesthetic outcomes. Moreover, for different patients, undergoing the same surgery, the aesthetic outcome could be completely different based on individual patient's factors (e.g age, body habitus). In the CINDERELLA project, we will be using the BreLO AI system (an artificial intelligence-based tool for classification of aesthetic outcomes and matching data and photographs) integrated in CANKADO (a cloud-based healthcare platform) to create an easy-to-use application that can be used on any electronic device, to simulate visually to the patient the aesthetic outcome of a certain surgery. The CINDERELLA APProach is unique as it uses a clinical database and performs biometric matching, to create images that simulate to the patient the outcome of surgery. In the CINDERELLA trial (running during the project) we plan to compare if the application helped to fulfil the expectation and lead to a better quality of life. By feeding new clinical and photographic information to the CINDERELLA APProach after surgery, the artificial intelligence platform will be able to improve for the next cases. This trial will be practice-changing in the field of patient education and shared decision making. CINDERELLA platform will help to overcome any miscommunication and potential boundaries in patient's or physician's understanding of the potential outcomes of locoregional treatment of breast cancer. We believe that the CINDERELLA APProach will be used in the future to other locoregional treatments that might change patients aesthetic appearance. Thus, CINDERELLA APProach will be the forerunner for new innovative tools for communicating with our patients.

Coordinatore

FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD
Contribution nette de l'UE
€ 866 750,00
Indirizzo
AVENIDA BRASILIA, CENTRO DE INVESTIGACAO DA FUNDACAO CHAMPALIMAUD
1400-038 Lisboa
Portogallo

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Regione
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Tipo di attività
Research Organisations
Collegamenti
Costo totale
€ 867 500,00

Partecipanti (9)