Psych-STRATA - A Stratified Treatment Algorithm in Psychiatry: A program on stratified pharmacogenomics in severe mental illness

Informazioni relative al progetto

Psych-STRATA

ID dell’accordo di sovvenzione: 101057454

DOI

10.3030/101057454

Data della firma CE 19 Maggio 2022

Data di avvio 1 Ottobre 2022

Data di completamento 30 Settembre 2027

Finanziato da

• Health

Costo totale

€ 10 276 440,00

Contributo UE

€ 10 276 440,00

Coordinato da

UNIVERSITAET MUENSTER
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (1)

Project website

The project website is set up and online.

Pubblicazioni

Peer reviewed articles (40)

Electroconvulsive therapy modulates the interplay between depressive symptoms in difficult-to-treat depression: A longitudinal network analysis

Autori: Marialaura Lussignoli, Marco Bortolomasi, Giulia Perusi, Giorgio Pigato, Alessandra Minelli, Fabio Sambataro
Pubblicato in: European Psychiatry, Numero 68, 2025, ISSN 0924-9338
Editore: Royal College of Psychiatrists
DOI: 10.1192/J.EURPSY.2025.10052

Plasma microRNA Levels After Electroconvulsive Therapy in Treatment-Resistant Depressed Patients

Autori: Chiara Galbiati, Vincenzo Dattilo, Marco Bortolomasi, Erika Vitali, Maria Abate, Valentina Menesello, Mattia Meattini, Rosana Carvalho Silva, Massimo Gennarelli, Luisella Bocchio Chiavetto, Alessandra Minelli
Pubblicato in: The Journal of ECT, 2025, ISSN 1533-4112
Editore: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/YCT.0000000000001100

IDENTIFYING DRUG TARGETS FOR SCHIZOPHRENIA THROUGH GENE PRIORITIZATION

Autori: Karl Heilbron, Julia Kraft, Alice Braun, Swapnil Awasthi, Georgia Panagiotaropoulou, Marijn Schipper, Nathaniel Bell, Danielle Posthuma, Antonio Pardiñas, Stephan Ripke
Pubblicato in: European Neuropsychopharmacology, Numero 87, 2024, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1101/2024.05.15.24307423

Polygenic overlap with granulocyte counts identifies novel loci for clozapine metabolism and clozapine-induced agranulocytosis

Autori: Elise Koch, Alexey A. Shadrin, Nadine Parker, Siobhan K. Lock, Robert L. Smith, Oleksandr Frei, Anders M. Dale, Srdjan Djurovic, Espen Molden, Kevin S. O´Connell, Ole A. Andreassen
Pubblicato in: Neuropsychopharmacology, Numero 50, 2025, ISSN 0893-133X
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41386-025-02054-X

Polygenic scores of subcortical brain volumes as possible modulators of treatment response in depression

Autori: V. Oliva, A. Martone, G. Fanelli, K. Domschke, A. Minelli, M. Gennarelli, P. Martini, M. Bortolomasi, E. Maron, A. Squassina, C. Pisanu, S. Kasper, J. Zohar, D. Souery, S. Montgomery, D. Albani, G. Forloni, P. Ferentinos, D. Rujescu, J. Mendlewicz, D. De
Pubblicato in: Neuroscience Applied, 2024, ISSN 2772-4085
Editore: Elsevier B.V.
DOI: 10.1016/j.nsa.2024.103937

The future of child and adolescent clinical psychopharmacology: A systematic review of phase 2, 3, or 4 randomized controlled trials of pharmacologic agents without regulatory approval or for unapproved indications

Autori: Samuele Cortese, Katherine McGinn, Mikkel Højlund, Alan Apter, Celso Arango, Immaculada Baeza, Tobias Banaschewski, Jan Buitelaar, Josefina Castro-Fornieles, David Coghill, David Cohen, Edna Grünblatt, Pieter J. Hoekstra, Anthony James, Pia Jeppesen, Péter Nagy, Anne Katrine Pagsberg, Mara Parellada, Antonio M. Persico, Diane Purper-Ouakil, Veit Roessner, Paramala Santosh, Emily Simonoff, Dejan Stevanovic, Argyris Stringaris, Benedetto Vitiello, Susanne Walitza, Abraham Weizman, Tamar Wohlfarth, Ian C.K. Wong, Gil Zalsman, Alessandro Zuddas, Carmen Moreno, Marco Solmi, Christoph U. Correll
Pubblicato in: Neuroscience & Biobehavioral Reviews, Numero 149, 2025, ISSN 0149-7634
Editore: Elsevier BV
DOI: 10.5167/UZH-232755

Genome-wide association studies on Northern Italy isolated populations provide further support concerning genetic susceptibility for major depressive disorder

Autori: Vincenzo Dattilo, Sheila Ulivi, Alessandra Minelli, Martina La Bianca, Edoardo Giacopuzzi, Marco Bortolomasi, Stefano Bignotti, Massimo Gennarelli, Paolo Gasparini, Maria Pina Concas
Pubblicato in: The World Journal of Biological Psychiatry, Numero 24, 2023, ISSN 1562-2975
Editore: Informa UK Limited
DOI: 10.1080/15622975.2022.2082523

Biomarkers of treatment-resistant schizophrenia: A systematic review

Autori: Claudia Pisanu, Giovanni Severino, Alessandra Minelli, Mara Dierssen, Marie-Claude Potier, Chiara Fabbri, Alessandro Serretti, Massimo Gennarelli, Bernhard T. Baune, Alessio Squassina
Pubblicato in: Neuroscience Applied, Numero 3, 2024, ISSN 2772-4085
Editore: Elsevier BV
DOI: 10.1016/J.NSA.2024.104059

Polygenic scores of subcortical brain volumes as possible modulators of treatment response in depression

Autori: Vincenzo Oliva, Alfonso Martone, Giuseppe Fanelli, Katharina Domschke, Alessandra Minelli, Massimo Gennarelli, Paolo Martini, Marco Bortolomasi, Eduard Maron, Alessio Squassina, Claudia Pisanu, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Diana De Ronchi, Bernhard T. Baune, Marie-Claude Potier, Roos van Westrhenen, Filip Rybakowski, Divya Mehta, Mara Dierssen, Joost G.E. Janzing, Pietro Liò, Alessandro Serretti, Chiara Fabbri
Pubblicato in: Neuroscience Applied, Numero 3, 2024, ISSN 2772-4085
Editore: Elsevier BV
DOI: 10.1101/2023.08.26.23294659

Automated Speech Analysis in Bipolar Disorder: The CALIBER Study Protocol and Preliminary Results

Autori: Gerard Anmella, Michele De Prisco, Jeremiah B. Joyce, Claudia Valenzuela-Pascual, Ariadna Mas-Musons, Vincenzo Oliva, Giovanna Fico, George Chatzisofroniou, Sanjeev Mishra, Majd Al-Soleiti, Filippo Corponi, Anna Giménez-Palomo, Laura Montejo, Meritxell González-Campos, Dina Popovic, Isabella Pacchiarotti, Marc Valentí, Myriam Cavero, Lluc Colomer, Iria Grande, Antoni Benabarre, Cristian-Daniel Llach, Joaquim Raduà, Melvin McInnis, Diego Hidalgo-Mazzei, Mark A. Frye, Andrea Murru, Eduard Vieta
Pubblicato in: Journal of Clinical Medicine, Numero 13, 2025, ISSN 2077-0383
Editore: MDPI AG
DOI: 10.3390/JCM13174997

Exploring the use of immunomethylomics in the characterization of depressed patients: A proof-of-concept study

Autori: Evelien Van Assche, Christa Hohoff, Ecem Su Atil, Sophia M. Wissing, Alessandro Serretti, Chiara Fabbri, Claudia Pisanu, Alessio Squassina, Alessandra Minelli, Bernhard T. Baune
Pubblicato in: Brain, Behavior, and Immunity, Numero 123, 2025, ISSN 0889-1591
Editore: Elsevier BV
DOI: 10.1016/J.BBI.2024.09.026

Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count

Autori: Siobhan K. Lock, Sophie E. Legge, Djenifer B. Kappel, Isabella R. Willcocks, Marinka Helthuis, John Jansen, James T. R. Walters, Michael J. Owen, Michael C. O’Donovan, Antonio F. Pardiñas
Pubblicato in: Schizophrenia, Numero 9, 2023, ISSN 2754-6993
Editore: Springer Science and Business Media LLC
DOI: 10.1101/2023.08.22.23294262

Anhedonia is associated with a specific depression profile and poor antidepressant response

Autori: Antonina Luca, Maria Luca, Siegfried Kasper, Basilio Pecorino, Joseph Zohar, Daniel Souery, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Antonino Messina, Raffaella Zanardi, Raffaele Ferri, Mariangela Tripodi, Bernhard T Baune, Giuseppe Fanelli, Chiara Fabbri, Julien Mendlewicz, Alessandro Serretti
Pubblicato in: International Journal of Neuropsychopharmacology, Numero 27, 2024, ISSN 1461-1457
Editore: Oxford University Press (OUP)
DOI: 10.1093/IJNP/PYAE055

Transdiagnostic Effects of Schizophrenia Polygenic Scores on Treatment Outcomes in Major Psychiatric Disorders

Autori: Alessandro Serretti, Bernhard Baune
Pubblicato in: Neuropsychiatric Disease and Treatment, Numero Volume 21, 2025, ISSN 1178-2021
Editore: Informa UK Limited
DOI: 10.2147/NDT.S514514

Evaluating study designs and treatment outcomes of antidepressant pharmacogenetic clinical trials - Challenges and future perspectives. A critical review

Autori: Alessandra Minelli, Stefano Barlati, Bernhard T Baune
Pubblicato in: European Neuropsychopharmacology, Numero 59, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2022.04.007

Distinct genetic liability profiles define clinically relevant patient strata across common diseases

Autori: Trastulla L, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M, Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Falkai P, Völzke H, Dörr M, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ.
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1101/2023.05.10.23289788

Mitochondrial DNA copy number is significantly increased in bipolar disorder patients and is correlated with long-term lithium treatment

Autori: Anna Meloni, Pasquale Paribello, Marco Pinna, Martina Contu, Raffaella Ardau, Caterina Chillotti, Donatella Congiu, Massimo Gennarelli, Alessandra Minelli, Lisa Buson, Giovanni Severino, Claudia Pisanu, Mirko Manchia, Alessio Squassina
Pubblicato in: European Neuropsychopharmacology, Numero 91, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2024.10.012

Effect of ketamine and esketamine on RNA expression and its relevance for depression: A systematic review

Autori: Claudia Pisanu, Rosana Carvalho Silva, Mattia Meattini, Massimo Gennarelli, Bernhard T. Baune, Alessio Squassina, Alessandra Minelli
Pubblicato in: Pharmacological Research, Numero 219, 2025, ISSN 1043-6618
Editore: Elsevier BV
DOI: 10.1016/J.PHRS.2025.107894

F37. PREDICTED PLASMA PROTEOMICS FROM GENETIC SCORES AND TREATMENT RESPONSE/RESISTANCE IN DEPRESSION

Autori: Chiara Fabbri, Vincenzo Oliva, Alessandra Minelli, Massimo Gennarelli, Alessio Squassina, Siegfried Kasper, Daniel Souery, Diego Albani, Raffaella Zanardi, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Bernhard Baune, Eduard Vieta, Alessandro Serretti
Pubblicato in: European Neuropsychopharmacology, Numero 87, 2024, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2024.08.448

Moving toward precision and personalized treatment strategies in psychiatry

Autori: Stefano Comai, Mirko Manchia, Marta Bosia, Alessandro Miola, Sara Poletti, Francesco Benedetti, Sofia Nasini, Raffaele Ferri, Dan Rujescu, Marion Leboyer, Julio Licinio, Bernhard T Baune, Alessandro Serretti
Pubblicato in: International Journal of Neuropsychopharmacology, Numero 28, 2025, ISSN 1461-1457
Editore: Oxford University Press (OUP)
DOI: 10.1093/IJNP/PYAF025

Neurobiological Perturbations in Bipolar Disorder Compared With Schizophrenia: Evidence From Cell Cultures and Brain Organoids

Autori: Ibrahim A. Akkouh, Jordi Requena Osete, Attila Szabo, Ole A. Andreassen, Srdjan Djurovic
Pubblicato in: Biological Psychiatry, Numero 98, 2025, ISSN 0006-3223
Editore: Elsevier BV
DOI: 10.1016/J.BIOPSYCH.2025.02.012

Recommendations for defining treatment outcomes in major psychiatric disorders using real-world data

Autori: Elise Koch, Sophie Smart, Guðmundur Einarsson, Anders Kämpe, Lina Jonsson, Maris Alver, Matthew Iveson, Andreas Göteson, Antonio F Pardiñas, Ida E Sønderby, Kevin S O'Connell, Qingqin Li, Yi Lu, Hreinn Stefánsson, Kári Stefánsson, Heather Whalley, Mikael Landén, Michael C O'Donovan, Knut Smerud, Gerard R Dawson, Thomas Werge, Alfonso Buil, Andreas Reif, Lili Milani, Espen Molden, Chiara Fabbri, Alessandro Serretti, James Walters, Cathryn M Lewis, Ole A Andreassen
Pubblicato in: The Lancet Psychiatry, Numero 12, 2025, ISSN 2215-0366
Editore: Elsevier BV
DOI: 10.31234/OSF.IO/KUMEA_V1

DNA methylation changes in association with trauma-focused psychotherapy efficacy in treatment-resistant depression patients: a prospective longitudinal study

Autori: Rosana Carvalho Silva, Paolo Martini, Christa Hohoff, Stefania Mattevi, Marco Bortolomasi, Valentina Menesello, Massimo Gennarelli, Bernhard T. Baune, Alessandra Minelli
Pubblicato in: European Journal of Psychotraumatology, Numero 15, 2024, ISSN 2000-8066
Editore: Informa UK Limited
DOI: 10.1080/20008066.2024.2314913

Biomarkers of treatment-resistant schizophrenia: A systematic review

Autori: C. Pisanu, G. Severino, A. Minelli, M. Dierssen, M.-C. Potier, C. Fabbri, A. Serretti, M. Gennarelli, European College of Neuropsychopharmacology (ECNP) Pharmacogenomics & Transcriptomics Network, B. T. Baune, A. Squassina
Pubblicato in: Neuroscience Applied, 2024, ISSN 2772-4085
Editore: Elsevier B.V.
DOI: 10.1016/j.nsa.2024.104059

iPSC-modelling reveals genetic associations and morphological alterations of oligodendrocytes in schizophrenia

Autori: Man-Hsin Chang, Jan Benedikt Waldeck, Marius Stephan, Nirmal Kannaiyan, Valéria de Almeida, Emanuel Boudriot, Temmuz Karali, Lukas Röll, Laura Fischer, Damianos Demetriou, Nadia Gabellini, Sabrina Galinski, Andrea Schmitt, Sergi Papiol, Daniel Keeser, Peter Falkai, Moritz J. Rossner, Florian J. Raabe
Pubblicato in: Translational Psychiatry, Numero 15, 2025, ISSN 2158-3188
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41398-025-03509-X

W33. A STRATIFIED TREATMENT ALGORITHM IN PSYCHIATRY (PSYCH-STRATA) - FIRST UPDATE FROM AN INTERNATIONAL GWAS OF TREATMENT-RESISTANT DEPRESSION (TRD)

Autori: Julia Kraft, Marisol Herrera-Rivero, Stephan Ripke, Chiara Fabbri, Bernhard T. Baune
Pubblicato in: European Neuropsychopharmacology, Numero 87, 2024, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2024.08.242

Leukocyte Telomere Length and Mitochondrial DNA Copy Number in Treatment-Resistant Depression and Response to Electroconvulsive Therapy

Autori: Alessio Squassina, Claudia Pisanu, Valentina Menesello, Anna Meloni, Donatella Congiu, Mirko Manchia, Pasquale Paribello, Maria Abate, Marco Bortolomasi, Bernhard T. Baune, Massimo Gennarelli, Alessandra Minelli
Pubblicato in: The Journal of ECT, Numero 41, 2025, ISSN 1533-4112
Editore: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/YCT.0000000000001060

A stratified treatment algorithm in psychiatry: a program on stratified pharmacogenomics in severe mental illness (Psych-STRATA): concept, objectives and methodologies of a multidisciplinary project funded by Horizon Europe

Autori: B. T. Baune, S. E. Fromme, M. Aberg, M. Adli, A. Afantitis, I. Akkouh, O. A. Andreassen, C. Angulo, S. Barlati, C. Brasso, P. Bucci, M. Budde, P. Buspavanich, V. Cavone, K. Demyttenaere, C. M. Diaz-Caneja, M. Dierssen, S. Djurovic, M. Driessen, U. W. Ebner-Priemer, J. Engelmann, S. Englisch, C. Fabbri, P. Fossati, H. Fröhlich, S. Gasser, N. Gottlieb, E. Heirman, A. Hofer, O. Howes, L. Ilzarbe, H. Jeung-Maarse, L. V. Kessing, T. D. Kockler, M. Landén, L. Levi, K. Lieb, N. Lorenzon, J. Luykx, M. Manchia, M. Martinez de Lagran, A. Minelli, C. Moreno, A. Mucci, B. Müller-Myhsok, P. Nilsson, C. Okhuijsen-Pfeifer, K. D. Papavasileiou, S. Papiol, A. F. Pardinas, P. Paribello, C. Pisanu, M. -C. Potier, A. Reif, R. Ricken, S. Ripke, P. Rocca, D. Scherrer, C. Schiweck, K. O. Schubert, T. G. Schulze, A. Serretti, A. Squassina, C. Stephan, A. Tsoumanis, E. Van der Eycken, E. Vieta, A. Vita, J. T. R. Walters, D. Weichert, M. Weiser, I. R. Willcocks, I. Winter-van Rossum, A. H. Young, M. J. Ziller
Pubblicato in: European Archives of Psychiatry and Clinical Neuroscience, Numero 275, 2025, ISSN 0940-1334
Editore: Springer Science and Business Media LLC
DOI: 10.1007/S00406-024-01944-3

Biological markers of sex-based differences in major depressive disorder and in antidepressant response

Autori: Rosana Carvalho Silva, Claudia Pisanu, Elisabetta Maffioletti, Valentina Menesello, Marco Bortolomasi, Massimo Gennarelli, Bernhard T Baune, Alessio Squassina, Alessandra Minelli
Pubblicato in: European Neuropsychopharmacology, Numero 76, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2023.07.012

Association of pharmacodynamic genes with treatment outcomes in major depressive disorder: results from a Sardinian cohort

Autori: Pasquale Paribello, Mirko Manchia, Marco Pinna, Martina Contu, Davide Orrù, Marco Upali, Sabrina El Kacemi, Ilaria Frau, Federico Suprani, Carolina Corrias, Giulia Somaini, Federica Pinna, Claudia Pisanu, Anna Meloni, Andrea Carta, Claudio Conversano, Francesco Mola, Maria Del Zompo, Lisa Buson, Massimo Gennarelli, Alessandra Minelli, Bernardo Carpiniello, Alessio Squassina
Pubblicato in: The Pharmacogenomics Journal, Numero 25, 2025, ISSN 1470-269X
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41397-025-00373-2

Unraveling epigenomic signatures and effectiveness of electroconvulsive therapy in treatment-resistant depression patients: a prospective longitudinal study

Autori: Rosana Carvalho Silva, Paolo Martini, Christa Hohoff, Stefania Mattevi, Marco Bortolomasi, Maria Abate, Valentina Menesello, Massimo Gennarelli, Bernhard T. Baune, Alessandra Minelli
Pubblicato in: Clinical Epigenetics, Numero 16, 2024, ISSN 1868-7083
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S13148-024-01704-Z

Transcriptional biomarkers of response to pharmacological treatments in severe mental disorders: A systematic review

Autori: Claudia Pisanu, Giovanni Severino, Ilario De Toma, Mara Dierssen, Paolo Fusar-Poli, Massimo Gennarelli, Pietro Lio, Elisabetta Maffioletti, Eduard Maron, Divya Mehta, Alessandra Minelli, Marie-Claude Potier, Alessandro Serretti, David Stacey, Roos van Westrhenen, Laura Xicota, Bernhard T Baune, Alessio Squassina
Pubblicato in: European Neuropsychopharmacology, Numero 55, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2021.12.005

Predicted plasma proteomics from genetic scores and treatment outcomes in major depression: a meta-analysis

Autori: Vincenzo Oliva, Chiara Possidente, Giuseppe Fanelli, Katharina Domschke, Alessandra Minelli, Massimo Gennarelli, Paolo Martini, Marco Bortolomasi, Alessio Squassina, Claudia Pisanu, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Bernhard T Baune, Eduard Vieta, Alessandro Serretti, Chiara Fabbri
Pubblicato in: European Neuropsychopharmacology, Numero 96, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2025.05.004

Mild motor signs and depression: more than just medication side effects?

Autori: Antonina Luca, Maria Luca, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Raffaele Zanardi, Raffaella Ferri, Bartolo Lanuzza, Basilio Pecorino, Bernhard T. Baune, Giuseppe Fanelli, Chiara Fabbri, Alessandro Serretti
Pubblicato in: European Archives of Psychiatry and Clinical Neuroscience, 2025, ISSN 0940-1334
Editore: Springer Science and Business Media LLC
DOI: 10.1007/S00406-025-02015-X

A meta-analysis of polygenic risk scores for mood disorders, neuroticism, and schizophrenia in antidepressant response

Autori: Giuseppe Fanelli, Katharina Domschke, Alessandra Minelli, Massimo Gennarelli, Paolo Martini, Marco Bortolomasi, Eduard Maron, Alessio Squassina, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Diana De Ronchi, Bernhard T Baune, Alessandro Serretti, Chiara Fabbri
Pubblicato in: European Neuropsychopharmacology, Numero 55, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2021.11.005

Digital mental health: challenges and next steps

Autori: Katharine A Smith, Charlotte Blease, Maria Faurholt-Jepsen, Joseph Firth, Tom Van Daele, Carmen Moreno, Per Carlbring, Ulrich W Ebner-Priemer, Nikolaos Koutsouleris, Heleen Riper, Stephane Mouchabac, John Torous, Andrea Cipriani
Pubblicato in: BMJ Mental Health, Numero 26, 2025, ISSN 2755-9734
Editore: BMJ
DOI: 10.5445/IR/1000160050

Prioritizing Parkinson’s disease risk genes in genome-wide association loci

Autori: Lara M. Lange, Catalina Cerquera-Cleves, Marijn Schipper, Georgia Panagiotaropoulou, Alice Braun, Julia Kraft, Swapnil Awasthi, Nathaniel Bell, Danielle Posthuma, Stephan Ripke, Cornelis Blauwendraat, Karl Heilbron
Pubblicato in: npj Parkinson's Disease, Numero 11, 2025, ISSN 2373-8057
Editore: Springer Science and Business Media LLC
DOI: 10.1101/2024.12.13.24318996

Association between a large change between the minimum and maximum monthly values of solar insolation and a history of suicide attempts in bipolar I disorder

Autori: Philipp Ritter, Tasha Glenn, Eric D. Achtyes, Martin Alda, Esen Agaoglu, Kürsat Altınbaş, Ole A. Andreassen, Elias Angelopoulos, Raffaella Ardau, Memduha Aydin, Yavuz Ayhan, Christopher Baethge, Rita Bauer, Bernhard T. Baune, Ceylan Balaban, Claudia Becerra-Palars, Aniruddh P. Behere, Prakash B. Behere, Habte Belete, Tilahun Belete, Gabriel Okawa Belizario, Frank Bellivier, Robert H. Belmaker, Francesco Benedetti, Michael Berk, Yuly Bersudsky, Şule Bicakci, Harriet Birabwa-Oketcho, Thomas D. Bjella, Conan Brady, Jorge Cabrera, Marco Cappucciati, Angela Marianne Paredes Castro, Wei-Ling Chen, Eric Y. W. Cheung, Silvia Chiesa, Margarita Chanopoulou, Marie Crowe, Alessandro Cuomo, Sara Dallaspezia, Pratikkumar Desai, Seetal Dodd, Bruno Etain, Andrea Fagiolini, Frederike T. Fellendorf, Ewa Ferensztajn-Rochowiak, Jess G. Fiedorowicz, Kostas N. Fountoulakis, Mark A. Frye, Pierre A. Geoffroy, Michael J. Gitlin, Ana Gonzalez-Pinto, John F. Gottlieb, Paul Grof, Bartholomeus C. M. Haarman, Hirohiko Harima, Mathias Hasse-Sousa, Chantal Henry, Lone Hoffding, Josselin Houenou, Massimiliano Imbesi, Erkki T. Isometsä, Maja Ivkovic, Sven Janno, Simon Johnsen, Flávio Kapczinski, Grigorios N. Karakatsoulis, Mathias Kardell, Lars Vedel Kessing, Seong Jae Kim, Barbara König, Timur L. Kot, Michael Koval, Mauricio Kunz, Beny Lafer, Mikael Landén, Erik R. Larsen, Rasmus W. Licht, Vera M. Ludwig, Carlos Lopez-Jaramillo, Alan MacKenzie, Helle Østergaard Madsen, Simone Alberte Kongstad A. Madsen, Jayant Mahadevan, Agustine Mahardika, Mirko Manchia, Wendy Marsh, Monica Martinez-Cengotitabengoa, Julia Martini, Klaus Martiny, Yuki Mashima, Declan M. McLoughlin, Alie N. R. Meesters, Ybe Meesters, Ingrid Melle, Fátima Meza-Urzúa, Elisabeth Michaelis, Pavol Mikolas, Yee Ming Mok, Scott Monteith, Muthukumaran Moorthy, Gunnar Morken, Enrica Mosca, Anton A. Mozzhegorov, Rodrigo Munoz, Starlin V. Mythri, Fethi Nacef, Ravi K. Nadella, Takako Nakanotani, René Ernst Nielsen, Claire O’Donovan, Adel Omrani, Yamima Osher, Uta Ouali, Maja Pantovic-Stefanovic, Pornjira Pariwatcharakul, Joanne Petite, Johannes Petzold, Andrea Pfennig, Maximilian Pilhatsch, Yolanda Pica Ruiz, Marco Pinna, Maurizio Pompili, Richard Porter, Danilo Quiroz, Francisco Diego Rabelo-da-Ponte, Raj Ramesar, Natalie Rasgon, Woraphat Ratta-apha, Maria Redahan, M. S. Reddy, Andreas Reif, Eva Z. Reininghaus, Jenny Gringer Richards, Janusz K. Rybakowski, Leela Sathyaputri, Angela M. Scippa, Christian Simhandl, Daniel Smith, José Smith, Paul W. Stackhouse, Dan J. Stein, Kellen Stilwell, Sergio Strejilevich, Kuan-Pin Su, Mythily Subramaniam, Ahmad Hatim Sulaiman, Kirsi Suominen, Andi J. Tanra, Yoshitaka Tatebayashi, Wen Lin Teh, Leonardo Tondo, Carla Torrent, Daniel Tuinstra, Takahito Uchida, Arne E. Vaaler, Eduard Vieta, Biju Viswanath, Carlo Volf, Kai-Jie Yang, Maria Yoldi-Negrete, Oguz Kaan Yalcinkaya, Allan H. Young, Yosra Zgueb, Peter C. Whybrow, Michael Bauer
Pubblicato in: International Journal of Bipolar Disorders, Numero 12, 2024, ISSN 2194-7511
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S40345-024-00364-5

Multi-omics data integration methods and their applications in psychiatric disorders

Autori: Anita Sathyanarayanan, Tamara T. Mueller, Mohammad Ali Moni, Katja Schueler, Bernhard T. Baune, Pietro Lio, Divya Mehta, Bernhard T Baune, Mara Dierssen, Bjarke Ebert, Chiara Fabbri, Paolo Fusar-Poli, Massimo Gennarelli, Catherine Harmer, Oliver D. Howes, Joost G.E. Janzing, Pietro Lio, Eduard Maron, Divya Mehta, Alessandra Minelli, Lara Nonell, Claudia Pisanu, Marie-Claude Potier, Filip Rybakowski, Alessandro Serretti, Alessio Squassina, David Stacey, Roos van Westrhenen, Laura Xicota
Pubblicato in: European Neuropsychopharmacology, Numero 69, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2023.01.001

A naturalistic retrospective evaluation of the utility of pharmacogenetic testing based on CYP2D6 e CYP2C19 profiling in antidepressants treatment in a cohort of patients with major depressive disorder

Autori: Alessio Squassina, Pasquale Paribello, Marco Pinna, Martina Contu, Claudia Pisanu, Donatella Congiu, Giovanni Severino, Anna Meloni, Andrea Carta, Claudio Conversano, Francesco Mola, Maria Del Zompo, Federico Bernoni d'Aversa, Alessandra Minelli, Massimo Gennarelli, Federica Pinna, Bernardo Carpiniello, Mirko Manchia
Pubblicato in: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Numero 137, 2025, ISSN 0278-5846
Editore: Elsevier BV
DOI: 10.1016/J.PNPBP.2025.111292