Running in the FAMILY - Understanding and predicting the intergenerational transmission of mental illness

Información del proyecto

FAMILY

Identificador del acuerdo de subvención: 101057529

DOI

10.3030/101057529

Fecha de la firma de la CE 24 Mayo 2022

Fecha de inicio 1 Octubre 2022

Fecha de finalización 30 Septiembre 2027

Financiado con arreglo a

• Health

Coste total

€ 10 906 409,75

Aportación de la UE

€ 10 906 409,75

Coordinado por

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (7)

1st version of data management, harmonisation, and open science plan
Report on the software pipelines based on simulation studies
Training plan
Marketing materials
1st report and plan for gender balance
Dissemination and Communication plan
Report on relevant outside initiatives and activities in the field and plan for collaboration

Other (2)

Registration numbers of the clinical studies (WHO Registry criteria)
Ethics institutional approvals

Websites, patent fillings, videos etc. (1)

Go-online of the public project website

Publicaciones

Peer reviewed articles (17)

Epigenetics applied to child and adolescent mental health: Progress, challenges and opportunities

Autores: Charlotte A. M. Cecil, Alexander Neumann, Esther Walto
Publicado en: JCPP Advances, Edición 3, 1, 2023, ISSN 2692-9384
Editor: CPP Advances Volume 3, Issue 1
DOI: 10.1186/s13073-023-01233-z

Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development

Autores: Hughes DE, Kunitoki K, Elyounssi S, Luo M, Bazer OM, Hopkinson CE, Dowling KF, Doyle AE, Dunn EC, Eryilmaz H, Gilman JM, Holt DJ, Valera EM, Smoller JW, Cecil CAM, Tiemeier H, Lee PH, Roffman JL.
Publicado en: Nature Neuroscience, Edición 26, 2023, ISSN 1546-1726
Editor: Nature Neuroscience
DOI: 10.1038/s41593-023-01321-8

Early-life stress and the gut microbiome: A comprehensive population-based investigation

Autores: Mulder RH, Kraaij R, Schuurmans IK, Frances-Cuesta C, Sanz Y, Medina-Gomez C, Duijts L, Rivadeneira F, Tiemeier H, Jaddoe VWV, Felix JF, Cecil CAM.
Publicado en: Brain, Behavior, and Immunity, 2024, ISSN 0889-1591
Editor: Brain, Behavior, and Immunity
DOI: 10.1016/j.bbi.2024.02.024

A systematic review of neuroimaging epigenetic research: calling for an increased focus on development

Autores: Walton E, Baltramonaityte V, Calhoun V, Heijmans BT, Thompson PM, Cecil CAM.
Publicado en: Molecular Psychiatry, Edición 28, 2023, ISSN 1476-5578
Editor: Molecular Psychiatry
DOI: 10.1038/s41380-023-02067-2

Exposure to prenatal infection and the developmentof internalizing and externalizing problems inchildren: a longitudinal population-based study

Autores: Suleri A, Rommel AS, Neumann A, Luo M, Hillegers M, de Witte L, Bergink V, Cecil CAM.
Publicado en: Journal of Child Psychology and Psychiatry, 2024, ISSN 1469-7610
Editor: Journal of Child Psychology and Psychiatry
DOI: 10.1111/jcpp.13923

Principal and independent genomic components of brain structure and function

Autores: Oblong LM,Soheili-Nezhad S, Trevisan N, Shi Y, Beckmann CF, Sprooten E
Publicado en: Genes, Brain and Behavior, 2024, ISSN 1601-183X
Editor: Genes, Brain and Behavior
DOI: 10.1111/gbb.12876

Risk factors for mood disorders among offspring of parents with bipolar disorder: Findings from a discordant-sibling study

Autores: Giacomo FD, Strippoli MF, Castelao E, Amoussou JR, Gholam M, Ranjbar S, Glaus J, Marquet P, Preisig M, Plessen KJ, Vandeleur CL.
Publicado en: Psychiatry Research, 2023, ISSN 0165-1781
Editor: Psychiatry Research
DOI: 10.1016/j.psychres.2023.115615

On Navigating Analytical Choices in Research on Early Life Adversity: A Commentary on Sisitsky et al. (2023).

Autores: Cecil CAM, Schuurmans IK. 
Publicado en: Research on Child and Adolescent Psychopathology, 2023, ISSN 2730-7174
Editor: Research on Child and Adolescent Psychopathology
DOI: 10.1007/S10802-023-01103-7

DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study.

Autores: Luo M, Walton E, Neumann A, Thio CHL, Felix JF, van IJzendoorn MH, Pappa I, Cecil CAM. 
Publicado en: Journal of Child Psychology and Psychiatry, 2024, ISSN 0021-9630
Editor: Journal of Child Psychology and Psychiatry
DOI: 10.1111/JCPP.13866

The role of lifestyle factors in the association between early-life stress and adolescent psycho-physical health: Moderation analysis in two European birth cohorts

Autores: Defina S, Woofenden T, Baltramonaityte V, Tiemeier H, Fairchild G, Felix JF, Cecil CAM, Walton E.
Publicado en: Preventive Medicine, 2024, ISSN 0091-7435
Editor: Preventive Medicine
DOI: 10.1016/j.ypmed.2024.107926

Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

Autores: Lazar-Contes I, Tanwar DK, Arzate-Meija RG, Steg LC, Feudijo OU, Crespo M, Germain PL, Mansuy IM
Publicado en: Genetics and Genomics, 2023, ISSN 2050-084X
Editor: eLife
DOI: 10.7554/eLife.91528.1

Cord Blood Metabolite Profiles and Their Association with Autistic Traits in Childhood

Autores: Kaupper CS, Blaauwendraad SM, Cecil CAM, Mulder RH, Gaillard R, Goncalves R, Borggraefe I, Koletzko B, Jaddoe VWV.
Publicado en: Metabolites, 2023, ISSN 2218-1989
Editor: Metabolites
DOI: 10.3390/metabo13111140

The epigenome under pressure: On regulatory adaptation to chronic stress in the brain. 

Autores: Arzate-Mejia RG, Carullo NVN, Mansuy IM.
Publicado en: Current Opinion in Neurobiology, 2023, ISSN 0959-4388
Editor: Current Opinion in Neurobiology
DOI: 10.1016/J.CONB.2023.102832

The bidirectional relationship between brain structure and physical activity: A longitudinal analysis in the UK Biobank

Autores: Rodriguez-Ayllon M, Neumann A, Hofman A, Vernooij MW, Neitzel J.
Publicado en: Neurobiology of Aging, 2024, ISSN 0197-4580
Editor: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2024.03.001

Neurobiology and systems biology of stress resilience. 

Autores: Kalisch R, Russo SJ, Müller MB.
Publicado en: Physiological Reviews, 2023, ISSN 0031-9333
Editor: Physiological Reviews
DOI: 10.1152/PHYSREV.00042.2023

Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.

Autores: Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, Blin O, Richardson JC, Bordet R, Lleó A, Alcolea D, Popp J, Marsh TW, Gorijala
Publicado en: Genome Medicine volume, 2023, ISSN 1756-994X
Editor: Genome Medicine volume
DOI: 10.1186/s13073-023-01233-z

Remembering through the genome: the role of chromatin states in brain functions and diseases

Autores: Arzate-Mejia RG, Mansuy IM.
Publicado en: Translational Psychiatry, Edición 122, 2023, ISSN 2158-3188
Editor: Translational Psychiatry
DOI: 10.1038/s41398-023-02415-4