Running in the FAMILY - Understanding and predicting the intergenerational transmission of mental illness

Project Information

FAMILY

Grant agreement ID: 101057529

DOI

10.3030/101057529

EC signature date 24 May 2022

Start date 1 October 2022

End date 30 September 2027

Funded under

• Health

Total cost

€ 10 906 409,75

EU contribution

€ 10 906 409,75

Coordinated by

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (7)

1st version of data management, harmonisation, and open science plan
Report on the software pipelines based on simulation studies
Training plan
Marketing materials
1st report and plan for gender balance
Dissemination and Communication plan
Report on relevant outside initiatives and activities in the field and plan for collaboration

Other (2)

Registration numbers of the clinical studies (WHO Registry criteria)
Ethics institutional approvals

Websites, patent fillings, videos etc. (1)

Go-online of the public project website

Publications

Peer reviewed articles (17)

Epigenetics applied to child and adolescent mental health: Progress, challenges and opportunities

Author(s): Charlotte A. M. Cecil, Alexander Neumann, Esther Walto
Published in: JCPP Advances, Issue 3, 1, 2023, ISSN 2692-9384
Publisher: CPP Advances Volume 3, Issue 1
DOI: 10.1186/s13073-023-01233-z

Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development

Author(s): Hughes DE, Kunitoki K, Elyounssi S, Luo M, Bazer OM, Hopkinson CE, Dowling KF, Doyle AE, Dunn EC, Eryilmaz H, Gilman JM, Holt DJ, Valera EM, Smoller JW, Cecil CAM, Tiemeier H, Lee PH, Roffman JL.
Published in: Nature Neuroscience, Issue 26, 2023, ISSN 1546-1726
Publisher: Nature Neuroscience
DOI: 10.1038/s41593-023-01321-8

Early-life stress and the gut microbiome: A comprehensive population-based investigation

Author(s): Mulder RH, Kraaij R, Schuurmans IK, Frances-Cuesta C, Sanz Y, Medina-Gomez C, Duijts L, Rivadeneira F, Tiemeier H, Jaddoe VWV, Felix JF, Cecil CAM.
Published in: Brain, Behavior, and Immunity, 2024, ISSN 0889-1591
Publisher: Brain, Behavior, and Immunity
DOI: 10.1016/j.bbi.2024.02.024

A systematic review of neuroimaging epigenetic research: calling for an increased focus on development

Author(s): Walton E, Baltramonaityte V, Calhoun V, Heijmans BT, Thompson PM, Cecil CAM.
Published in: Molecular Psychiatry, Issue 28, 2023, ISSN 1476-5578
Publisher: Molecular Psychiatry
DOI: 10.1038/s41380-023-02067-2

Exposure to prenatal infection and the developmentof internalizing and externalizing problems inchildren: a longitudinal population-based study

Author(s): Suleri A, Rommel AS, Neumann A, Luo M, Hillegers M, de Witte L, Bergink V, Cecil CAM.
Published in: Journal of Child Psychology and Psychiatry, 2024, ISSN 1469-7610
Publisher: Journal of Child Psychology and Psychiatry
DOI: 10.1111/jcpp.13923

Principal and independent genomic components of brain structure and function

Author(s): Oblong LM,Soheili-Nezhad S, Trevisan N, Shi Y, Beckmann CF, Sprooten E
Published in: Genes, Brain and Behavior, 2024, ISSN 1601-183X
Publisher: Genes, Brain and Behavior
DOI: 10.1111/gbb.12876

Risk factors for mood disorders among offspring of parents with bipolar disorder: Findings from a discordant-sibling study

Author(s): Giacomo FD, Strippoli MF, Castelao E, Amoussou JR, Gholam M, Ranjbar S, Glaus J, Marquet P, Preisig M, Plessen KJ, Vandeleur CL.
Published in: Psychiatry Research, 2023, ISSN 0165-1781
Publisher: Psychiatry Research
DOI: 10.1016/j.psychres.2023.115615

On Navigating Analytical Choices in Research on Early Life Adversity: A Commentary on Sisitsky et al. (2023).

Author(s): Cecil CAM, Schuurmans IK. 
Published in: Research on Child and Adolescent Psychopathology, 2023, ISSN 2730-7174
Publisher: Research on Child and Adolescent Psychopathology
DOI: 10.1007/S10802-023-01103-7

DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study.

Author(s): Luo M, Walton E, Neumann A, Thio CHL, Felix JF, van IJzendoorn MH, Pappa I, Cecil CAM. 
Published in: Journal of Child Psychology and Psychiatry, 2024, ISSN 0021-9630
Publisher: Journal of Child Psychology and Psychiatry
DOI: 10.1111/JCPP.13866

The role of lifestyle factors in the association between early-life stress and adolescent psycho-physical health: Moderation analysis in two European birth cohorts

Author(s): Defina S, Woofenden T, Baltramonaityte V, Tiemeier H, Fairchild G, Felix JF, Cecil CAM, Walton E.
Published in: Preventive Medicine, 2024, ISSN 0091-7435
Publisher: Preventive Medicine
DOI: 10.1016/j.ypmed.2024.107926

Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

Author(s): Lazar-Contes I, Tanwar DK, Arzate-Meija RG, Steg LC, Feudijo OU, Crespo M, Germain PL, Mansuy IM
Published in: Genetics and Genomics, 2023, ISSN 2050-084X
Publisher: eLife
DOI: 10.7554/eLife.91528.1

Cord Blood Metabolite Profiles and Their Association with Autistic Traits in Childhood

Author(s): Kaupper CS, Blaauwendraad SM, Cecil CAM, Mulder RH, Gaillard R, Goncalves R, Borggraefe I, Koletzko B, Jaddoe VWV.
Published in: Metabolites, 2023, ISSN 2218-1989
Publisher: Metabolites
DOI: 10.3390/metabo13111140

The epigenome under pressure: On regulatory adaptation to chronic stress in the brain. 

Author(s): Arzate-Mejia RG, Carullo NVN, Mansuy IM.
Published in: Current Opinion in Neurobiology, 2023, ISSN 0959-4388
Publisher: Current Opinion in Neurobiology
DOI: 10.1016/J.CONB.2023.102832

The bidirectional relationship between brain structure and physical activity: A longitudinal analysis in the UK Biobank

Author(s): Rodriguez-Ayllon M, Neumann A, Hofman A, Vernooij MW, Neitzel J.
Published in: Neurobiology of Aging, 2024, ISSN 0197-4580
Publisher: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2024.03.001

Neurobiology and systems biology of stress resilience. 

Author(s): Kalisch R, Russo SJ, Müller MB.
Published in: Physiological Reviews, 2023, ISSN 0031-9333
Publisher: Physiological Reviews
DOI: 10.1152/PHYSREV.00042.2023

Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.

Author(s): Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, Blin O, Richardson JC, Bordet R, Lleó A, Alcolea D, Popp J, Marsh TW, Gorijala
Published in: Genome Medicine volume, 2023, ISSN 1756-994X
Publisher: Genome Medicine volume
DOI: 10.1186/s13073-023-01233-z

Remembering through the genome: the role of chromatin states in brain functions and diseases

Author(s): Arzate-Mejia RG, Mansuy IM.
Published in: Translational Psychiatry, Issue 122, 2023, ISSN 2158-3188
Publisher: Translational Psychiatry
DOI: 10.1038/s41398-023-02415-4