Running in the FAMILY - Understanding and predicting the intergenerational transmission of mental illness | FAMILY | Progetto | Risultati | HORIZON | CORDIS

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

1st version of data management, harmonisation, and open science plan
Report on the software pipelines based on simulation studies
Training plan
Marketing materials
1st report and plan for gender balance
Dissemination and Communication plan
Report on relevant outside initiatives and activities in the field and plan for collaboration

Registration numbers of the clinical studies (WHO Registry criteria)
Ethics institutional approvals

Go-online of the public project website

Pubblicazioni

Epigenetics applied to child and adolescent mental health: Progress, challenges and opportunities

Autori: Charlotte A. M. Cecil, Alexander Neumann, Esther Walto
Pubblicato in: JCPP Advances, Numero 3, 1, 2023, ISSN 2692-9384
Editore: CPP Advances Volume 3, Issue 1
DOI: 10.1186/s13073-023-01233-z

Early-life stress and the gut microbiome: A comprehensive population-based investigation

Autori: Rosa H. Mulder, Robert Kraaij, Isabel K. Schuurmans, Carlos Frances-Cuesta, Yolanda Sanz, Carolina Medina-Gomez, Liesbeth Duijts, Fernando Rivadeneira, Henning Tiemeier, Vincent W.V. Jaddoe, Janine F. Felix, Charlotte A.M. Cecil
Pubblicato in: Brain, Behavior, and Immunity, Numero 118, 2025, ISSN 0889-1591
Editore: Elsevier BV
DOI: 10.1016/J.BBI.2024.02.024

Understanding and predicting the intergenerational transmission of mental illness

Autori: Nina Karguth, Lisanne A.E.M. van Houtum, Jörg M Fegert, Karen Schlaegel, Andrea Raballo, John Saunders, André Decraene, Neeltje E.M. van Haren
Pubblicato in: Open Access Government, Numero 44, 2024, ISSN 2516-3817
Editore: Adjacent Digital Politics Ltd
DOI: 10.56367/OAG-044-11713

Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development

Autori: Hughes DE, Kunitoki K, Elyounssi S, Luo M, Bazer OM, Hopkinson CE, Dowling KF, Doyle AE, Dunn EC, Eryilmaz H, Gilman JM, Holt DJ, Valera EM, Smoller JW, Cecil CAM, Tiemeier H, Lee PH, Roffman JL.
Pubblicato in: Nature Neuroscience, Numero 26, 2023, ISSN 1546-1726
Editore: Nature Neuroscience
DOI: 10.1038/s41593-023-01321-8

Plasma circulating microRNAs and symptoms of depression: Results from a population‐based study

Autori: Midas M. Kuilman, Tim Finke, M. Arfan Ikram, Annemarie I. Luik, Alexander Neumann, Charlotte A.M. Cecil, Mohsen Ghanbari
Pubblicato in: Psychiatry and Clinical Neurosciences, Numero 79, 2025, ISSN 1323-1316
Editore: Wiley
DOI: 10.1111/PCN.13869

Early-life stress and the gut microbiome: A comprehensive population-based investigation

Autori: Mulder RH, Kraaij R, Schuurmans IK, Frances-Cuesta C, Sanz Y, Medina-Gomez C, Duijts L, Rivadeneira F, Tiemeier H, Jaddoe VWV, Felix JF, Cecil CAM.
Pubblicato in: Brain, Behavior, and Immunity, 2024, ISSN 0889-1591
Editore: Brain, Behavior, and Immunity
DOI: 10.1016/j.bbi.2024.02.024

Running in the FAMILY: understanding and predicting the intergenerational transmission of mental illness

Autori: Lisanne A. E. M. van Houtum, William F. C. Baaré, Christian F. Beckmann, Josefina Castro-Fornieles, Charlotte A. M. Cecil, Juliane Dittrich, Bjørn H. Ebdrup, Jörg M. Fegert, Alexandra Havdahl, Manon H. J. Hillegers, Raffael Kalisch, Steven A. Kushner, Isabelle M. Mansuy, Signe Mežinska, Carmen Moreno, Ryan L. Muetzel, Alexander Neumann, Merete Nordentoft, Jean-Baptiste Pingault, Martin Preisig, Andrea Raballo, John Saunders, Emma Sprooten, Gisela Sugranyes, Henning Tiemeier, Geeske M. van Woerden, Caroline L. Vandeleur, Neeltje E. M. van Haren
Pubblicato in: European Child & Adolescent Psychiatry, Numero 33, 2024, ISSN 1018-8827
Editore: Springer Science and Business Media LLC
DOI: 10.1007/S00787-024-02423-9

Ethical and social issues in prediction of risk of severe mental illness: a scoping review and thematic analysis

Autori: Ivars Neiders, Signe Mežinska, Neeltje E. M. van Haren
Pubblicato in: BMC Psychiatry, Numero 25, 2025, ISSN 1471-244X
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S12888-025-06949-3

Comparable 40 Hz auditory steady-state responses in children at familial high risk for schizophrenia or bipolar disorder and population-based controls

Autori: Kit Melissa Larsen, Júlia Díaz-i-Calvete, Anna Hester Ver Loren van Themaat, Anne Amalie Elgaard Thorup, Kerstin Jessica Plessen, Merete Nordentoft, Hartwig Roman Siebner
Pubblicato in: NeuroImage: Clinical, Numero 48, 2025, ISSN 2213-1582
Editore: Elsevier BV
DOI: 10.1016/J.NICL.2025.103841

Unified high-resolution immune cell fraction estimation in blood tissue from birth to old age

Autori: Xiaolong Guo, Mahnoor Sulaiman, Alexander Neumann, Shijie C. Zheng, Charlotte A.M. Cecil, Andrew E. Teschendorff, Bastiaan T. Heijmans
Pubblicato in: Genome Medicine, Numero 17, 2025, ISSN 1756-994X
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S13073-025-01489-7

Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

Autori: Irina Lazar-Contes, Rodrigo G Arzate-Mejia, Deepak K Tanwar, Leonard C Steg, Kerem Uzel, Olivier Ulrich Feudjio, Marion Crespo, Pierre-Luc Germain, Isabelle M Mansuy
Pubblicato in: eLife, Numero 12, 2025, ISSN 2050-084X
Editore: eLife Sciences Publications, Ltd
DOI: 10.7554/ELIFE.91528.3

Non-linear development of brain morphometry in child and adolescent offspring of individuals with bipolar disorder or schizophrenia

Autori: Simon R. Poortman, Nikita Setiaman, Marjolein E.A. Barendse, Hugo G. Schnack, Manon H.J. Hillegers, Neeltje E.M. van Haren
Pubblicato in: European Neuropsychopharmacology, Numero 87, 2024, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2024.06.011

Inflammatory markers in pregnancy – identifying drivers in four large cohorts

Autori: Frederieke A. J. Gigase, Anna Suleri, Elena Isaevska, Anna-Sophie Rommel, Myrthe G. B. M. Boekhorst, Olga Dmitrichenko, Hanan El Marroun, Eric A. P. Steegers, Manon H. J. Hillegers, Ryan L. Muetzel, Whitney Lieb, Charlotte A. M. Cecil, Victor J. M. Pop, Michael Breen, Veerle Bergink, Lot D. de Witte
Pubblicato in: Frontiers in Immunology, Numero 16, 2025, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/FIMMU.2025.1561798

A systematic review of neuroimaging epigenetic research: calling for an increased focus on development

Autori: Walton E, Baltramonaityte V, Calhoun V, Heijmans BT, Thompson PM, Cecil CAM.
Pubblicato in: Molecular Psychiatry, Numero 28, 2023, ISSN 1476-5578
Editore: Molecular Psychiatry
DOI: 10.1038/s41380-023-02067-2

Exposure to prenatal infection and the developmentof internalizing and externalizing problems inchildren: a longitudinal population-based study

Autori: Suleri A, Rommel AS, Neumann A, Luo M, Hillegers M, de Witte L, Bergink V, Cecil CAM.
Pubblicato in: Journal of Child Psychology and Psychiatry, 2024, ISSN 1469-7610
Editore: Journal of Child Psychology and Psychiatry
DOI: 10.1111/jcpp.13923

Principal and independent genomic components of brain structure and function

Autori: Oblong LM,Soheili-Nezhad S, Trevisan N, Shi Y, Beckmann CF, Sprooten E
Pubblicato in: Genes, Brain and Behavior, 2024, ISSN 1601-183X
Editore: Genes, Brain and Behavior
DOI: 10.1111/gbb.12876

Participant engagement and involvement in longitudinal cohort studies: qualitative insights from a selection of pregnancy and birth, twin, and family-based population cohort studies

Autori: Isabelle Budin-Ljøsne, Nanna A. G. Fredheim, Charlotte Alison Jevne, Bojana Milanovic Kleven, Marie Aline Charles, Janine F. Felix, Robin Flaig, María Paz García, Alexandra Havdahl, Shahid Islam, Shona M. Kerr, Inger Kristine Meder, Lynn Molloy, Susan M. B. Morton, Costanza Pizzi, Aamnah Rahman, Gonneke Willemsen, Diane Wood, Jennifer R. Harris
Pubblicato in: BMC Medical Research Methodology, Numero 24, 2024, ISSN 1471-2288
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S12874-024-02419-8

Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium

Autori: Alexander Neumann, Sara Sammallahti, Marta Cosin-Tomas, Sarah E. Reese, Matthew Suderman, Silvia Alemany, Catarina Almqvist, Sandra Andrusaityte, Syed H. Arshad, Marian J. Bakermans-Kranenburg, Lawrence Beilin, Carrie Breton, Mariona Bustamante, Darina Czamara, Dana Dabelea, Celeste Eng, Brenda Eskenazi, Bernard F. Fuemmeler, Frank D. Gilliland, Regina Grazuleviciene, Siri E. Håberg, Gunda Herberth, Nina Holland, Amy Hough, Donglei Hu, Karen Huen, Anke Hüls, Marjo-Riitta Jarvelin, Jianping Jin, Jordi Julvez, Berthold V. Koletzko, Gerard H. Koppelman, Inger Kull, Xueling Lu, Léa Maitre, Dan Mason, Erik Melén, Simon K. Merid, Peter L. Molloy, Trevor A. Mori, Rosa H. Mulder, Christian M. Page, Rebecca C. Richmond, Stefan Röder, Jason P. Ross, Laura Schellhas, Sylvain Sebert, Dean Sheppard, Harold Snieder, Anne P. Starling, Dan J. Stein, Gwen Tindula, Marinus H. van IJzendoorn, Judith Vonk, Esther Walton, Jonathan Witonsky, Cheng-Jian Xu, Ivana V. Yang, Paul D. Yousefi, Heather J. Zar, Ana C. Zenclussen, Hongmei Zhang, Henning Tiemeier, Stephanie J. London, Janine F. Felix, Charlotte Cecil
Pubblicato in: Genome Medicine, Numero 17, 2025, ISSN 1756-994X
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S13073-025-01451-7

Genetic Susceptibility to Neurodevelopmental Conditions Is Associated With Neonatal DNA Methylation Patterns in the General Population: An Individual Participant Data Meta-Analysis

Autori: Isabel K. Schuurmans, Dinka Smajlagic, Vilte Baltramonaityte, Anni L.K. Malmberg, Alexander Neumann, Nicole Creasey, Janine F. Felix, Henning Tiemeier, Jean-Baptiste Pingault, Darina Czamara, Katri Raïkkönen, Christian Magnus Page, Robert Lyle, Alexandra Havdahl, Jari Lahti, Esther Walton, Mona Bekkhus, Charlotte A.M. Cecil
Pubblicato in: Biological Psychiatry, 2025, ISSN 0006-3223
Editore: Elsevier BV
DOI: 10.1016/J.BIOPSYCH.2025.09.005

Perinatal Maternal Depressive Symptoms and Brain Connectivity Among 9- to 15-Year-Old Offspring

Autori: Dogukan Koc, Adriana P. C. Hermans, Bing Xu, Ryan L. Muetzel, Hanan El Marroun, Henning Tiemeier
Pubblicato in: JAMA Network Open, Numero 8, 2025, ISSN 2574-3805
Editore: American Medical Association (AMA)
DOI: 10.1001/JAMANETWORKOPEN.2025.23978

Prenatal exposure to common infections and newborn DNA methylation: A prospective, population-based study

Autori: Anna Suleri, Kristina Salontaji, Mannan Luo, Alexander Neumann, Rosa H. Mulder, Henning Tiemeier, Janine F. Felix, Riccardo E. Marioni, Veerle Bergink, Charlotte A.M. Cecil
Pubblicato in: Brain, Behavior, and Immunity, Numero 121, 2024, ISSN 0889-1591
Editore: Elsevier BV
DOI: 10.1016/J.BBI.2024.07.046

Prenatal maternal stress: triangulating evidence for intrauterine exposure effects on birth and early childhood outcomes across multiple approaches

Autori: Ingunn Olea Lund, Laurie J. Hannigan, Helga Ask, Adrian D. Askelund, Laura Hegemann, Elizabeth C. Corfield, Robyn E. Wootton, Yasmin I. Ahmadzadeh, George Davey Smith, Tom A. McAdams, Eivind Ystrom, Alexandra Havdahl
Pubblicato in: BMC Medicine, Numero 23, 2025, ISSN 1741-7015
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S12916-024-03834-W

Associations between genetic predisposition to mental health problems and academic achievement: a developmental perspective using two population‐based cohorts

Autori: Marie‐Pier Larose, Isabel Schuurmans, Edward D. Barker, Liliana Garcia Mondragon, Henning Tiemeier, Irwin Waldman, Charlotte Cecil
Pubblicato in: Journal of Child Psychology and Psychiatry, 2025, ISSN 0021-9630
Editore: Wiley
DOI: 10.1111/JCPP.70043

Risk factors for mood disorders among offspring of parents with bipolar disorder: Findings from a discordant-sibling study

Autori: Giacomo FD, Strippoli MF, Castelao E, Amoussou JR, Gholam M, Ranjbar S, Glaus J, Marquet P, Preisig M, Plessen KJ, Vandeleur CL.
Pubblicato in: Psychiatry Research, 2023, ISSN 0165-1781
Editore: Psychiatry Research
DOI: 10.1016/j.psychres.2023.115615

Prenatal stress, epigenetically-assessed glucocorticoid exposure at birth, and child psychiatric symptoms: A prospective, multi-cohort study

Autori: Nicole Creasey, Isabel Schuurmans, Stella Tsotsi, Serena Defina, Vilte Baltramonaityte, Janine F. Felix, Alexander Neumann, Christian M. Page, Marieke Tollenaar, Mona Bekkhus, Esther Walton, Charlotte Cecil
Pubblicato in: Psychoneuroendocrinology, Numero 175, 2025, ISSN 0306-4530
Editore: Elsevier BV
DOI: 10.1016/J.PSYNEUEN.2025.107388

Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders

Autori: Nora R. Bakken, Nadine Parker, Laurie J. Hannigan, Espen Hagen, Pravesh Parekh, Alexey Shadrin, Piotr Jaholkowski, Evgeniia Frei, Viktoria Birkenæs, Guy Hindley, Laura Hegemann, Elizabeth C. Corfield, Martin Tesli, Alexandra Havdahl, Ole A. Andreassen
Pubblicato in: Journal of Child Psychology and Psychiatry, Numero 66, 2025, ISSN 0021-9630
Editore: Wiley
DOI: 10.1111/JCPP.14063

On Navigating Analytical Choices in Research on Early Life Adversity: A Commentary on Sisitsky et al. (2023).

Autori: Cecil CAM, Schuurmans IK.
Pubblicato in: Research on Child and Adolescent Psychopathology, 2023, ISSN 2730-7174
Editore: Research on Child and Adolescent Psychopathology
DOI: 10.1007/S10802-023-01103-7

Thalamocortical Structural Covariation Networks Are Related to Familial Risk for Schizophrenia in the Context of Lower Nuclei Volume Estimates in Patients: An ENIGMA Study

Autori: Annalisa Lella, Linda A. Antonucci, Roberta Passiatore, Loredana Bellantuono, Pierluigi Selvaggi, Teresa Popolizio, Guido Di Sciascio, Alessandro Saponaro, Patrizia Ricci, Mario Altamura, Giuseppe Blasi, Antonio Rampino, Chris Vriend, Vince D. Calhoun, Kelly Rootes-Murdy, Aaron L. Goldman, Inmaculada Baeza, Josefina Castro-Fornieles, Gisela Sugranyes, Elena De la Serna, Edith Pomarol-Clotet, Mar Fatjó-Vilas, Raymond Salvador, Andriana Karuk, Paola Fuentes-Claramonte, David C. Glahn, Amanda L. Rodrigue, John Blangero, Lei Wang, Taeyoung Lee, Karolin E. Einenkel, Saskia Hamers, Oliver Gruber, Adrian Preda, Young-Chul Chung, Soyolsaikhan Odkhuu, Corentin Vallée, Paola Dazzan, Machteld Marcelis, Stijn Michielse, Katharina Brosch, Frederike Stein, Igor Nenadić, Benjamin Straube, Florian Thomas-Odenthal, Tilo Kircher, Sean Carruthers, Susan L. Rossell, Phillip J. Sumner, Tamsyn E. Van Rheenen, Caroline Demro, Ian S. Ramsay, Scott R. Sponheim, Rebekka Lencer, Susanne Meinert, Tim Hahn, Udo Dannlowski, Dominik Grotegerd, Mariateresa Ciccarelli, Felice Iasevoli, Giuseppe Pontillo, Godfrey D. Pearlson, Derin Cobia, Fabrizio Piras, Nerisa Banaj, Daniela Vecchio, Marjolein E.A. Barendse, Neeltje E.M. van Haren, Hang Joon Jo, Kang Sim, Yann Quidé, Melissa J. Green, Rachael Slate, Giacomo Cecere, Wolfgang Omlor, Stephanie Homan, Philipp Homan, Sophia I. Thomopoulos, Anna Manzari, Antonello Bellomo, Jessica A. Turner, Theo G.M. van Erp, Paul M. Thompson, Alessandro Bertolino, Giulio Pergola
Pubblicato in: Biological Psychiatry, Numero 98, 2025, ISSN 0006-3223
Editore: Elsevier BV
DOI: 10.1016/J.BIOPSYCH.2025.03.027

Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium

Autori: Isabel K. Schuurmans, Rosa H. Mulder, Vilte Baltramonaityte, Alexandra Lahtinen, Fan Qiuyu, Leonardo Melo Rothmann, Marlene Staginnus, Jetro J. Tuulari, S. Alexandra Burt, Claudia Buss, Jeffrey M. Craig, Kirsten A. Donald, Johan G. Eriksson, Janine F. Felix, Tom P. Freeman, Rodrigo Grassi-Oliveira, Anke Huels, Luke W. Hyde, Scott A. Jones, Hasse Karlsson, Linnea Karlsson, Nastassja Koen, Will Lawn, Colter Mitchell, Christopher S. Monk, Michael A. Mooney, Ryan Muetzel, Joel T. Nigg, Síntia Iole Nogueira Belangero, Daniel Notterman, Yi Ying Ong, Tom O’Connor, Kieran J. O’Donnell, Pedro Mario Pan, Tiina Paunio, Peter Ryabinin, Richard Saffery, Giovanni A. Salum, Marc Seal, Tim J. Silk, Dan J. Stein, Ai Peng Tan, Ai Ling Teh, Dennis Wang, Heather Zar, Esther Walton, Charlotte A. M. Cecil
Pubblicato in: Molecular Psychiatry, 2025, ISSN 1359-4184
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41380-025-03203-W

Principal and independent genomic components of brain structure and function

Autori: Lennart M. Oblong, Sourena Soheili‐Nezhad, Nicolò Trevisan, Yingjie Shi, Christian F. Beckmann, Emma Sprooten
Pubblicato in: Genes, Brain and Behavior, Numero 23, 2024, ISSN 1601-1848
Editore: Wiley
DOI: 10.1111/GBB.12876

Examining longitudinal associations between prenatal exposure to infections and child brain morphology

Autori: Anna Suleri, Carolin Gaiser, Charlotte A.M. Cecil, Annet Dijkzeul, Alexander Neumann, Jeremy A. Labrecque, Tonya White, Veerle Bergink, Ryan L. Muetzel
Pubblicato in: Brain, Behavior, and Immunity, Numero 119, 2024, ISSN 0889-1591
Editore: Elsevier BV
DOI: 10.1016/J.BBI.2024.05.014

DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study.

Autori: Luo M, Walton E, Neumann A, Thio CHL, Felix JF, van IJzendoorn MH, Pappa I, Cecil CAM.
Pubblicato in: Journal of Child Psychology and Psychiatry, 2024, ISSN 0021-9630
Editore: Journal of Child Psychology and Psychiatry
DOI: 10.1111/JCPP.13866

The role of lifestyle factors in the association between early-life stress and adolescent psycho-physical health: Moderation analysis in two European birth cohorts

Autori: Defina S, Woofenden T, Baltramonaityte V, Tiemeier H, Fairchild G, Felix JF, Cecil CAM, Walton E.
Pubblicato in: Preventive Medicine, 2024, ISSN 0091-7435
Editore: Preventive Medicine
DOI: 10.1016/j.ypmed.2024.107926

The bidirectional relationship between brain structure and physical activity: A longitudinal analysis in the UK Biobank

Autori: María Rodriguez-Ayllon, Alexander Neumann, Amy Hofman, Meike W. Vernooij, Julia Neitzel
Pubblicato in: Neurobiology of Aging, Numero 138, 2025, ISSN 0197-4580
Editore: Elsevier BV
DOI: 10.1016/J.NEUROBIOLAGING.2024.03.001

Polygenic Scores and Mood Disorder Onsets in the Context of Family History and Early Psychopathology

Autori: Kathryn Freeman, Alyson Zwicker, Janice M. Fullerton, Danella M. Hafeman, Neeltje E. M. van Haren, John Merranko, Benjamin I. Goldstein, Emma K. Stapp, Elena de la Serna, Dolores Moreno, Gisela Sugranyes, Sergi Mas, Gloria Roberts, Claudio Toma, Peter R. Schofield, Howard J. Edenberg, Holly C. Wilcox, Melvin G. McInnis, Lukas Propper, Barbara Pavlova, Samuel A. Stewart, Eileen M. Denovan-Wright, Guy A. Rouleau, Josefina Castro-Fornieles, Manon H. J. Hillegers, Boris Birmaher, Philip B. Mitchell, Martin Alda, John I. Nurnberger, Rudolf Uher
Pubblicato in: JAMA Network Open, Numero 8, 2025, ISSN 2574-3805
Editore: American Medical Association (AMA)
DOI: 10.1001/JAMANETWORKOPEN.2025.5331

Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium

Autori: Siwen Wang, Emma Casey, Joanne Sordillo, Sofía Aguilar-Lacasaña, Fernanda Morales Berstein, Richard J. Biedrzycki, Sonia Brescianini, Su Chen, Amy Hough, Elena Isaevska, Woo Jin Kim, Marion Lecorguillé, Sebastian Shaobo Li, Christian M. Page, Jaehyun Park, Stefan Röder, Kristina Salontaji, Gillian Santorelli, Yidan Sun, Sungho Won, Eric Zillich, Lea Zillich, Isabella Annesi-Maesano, S. Hasan Arshad, Mariona Bustamante, Charlotte A. M. Cecil, Hannah R. Elliott, Susan Ewart, Janine F. Felix, Luigi Gagliardi, Siri E. Håberg, Gunda Herberth, Barbara Heude, John W. Holloway, Anke Huels, Wilfried Karmaus, Gerard H. Koppelman, Stephanie J. London, Sunni L. Mumford, Lorenza Nisticò, Maja Popovic, Franca Rusconi, Enrique F. Schisterman, Dan J. Stein, Tabea Send, Henning Tiemeier, Judith M. Vonk, Martine Vrijheid, Joseph Leo Wiemels, Stephanie H. Witt, John Wright, Edwina H. Yeung, Heather J. Zar, Ana C. Zenclussen, Hongmei Zhang, Jorge E. Chavarro, Marie-France Hivert
Pubblicato in: Science Advances, Numero 10, 2024, ISSN 2375-2548
Editore: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADR2084

Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

Autori: Lazar-Contes I, Tanwar DK, Arzate-Meija RG, Steg LC, Feudijo OU, Crespo M, Germain PL, Mansuy IM
Pubblicato in: Genetics and Genomics, 2023, ISSN 2050-084X
Editore: eLife
DOI: 10.7554/eLife.91528.1

A father’s legacy: the sperm epigenome, preimplantation development, and paternal environment

Autori: Leonard C. Steg, Isabelle M. Mansuy
Pubblicato in: Epigenomics, 2025, ISSN 1750-1911
Editore: Informa UK Limited
DOI: 10.1080/17501911.2025.2569301

Mapping prenatal predictors and neurobehavioral outcomes of an epigenetic marker of neonatal inflammation – A longitudinal population-based study

Autori: Anna Suleri, Nicole Creasey, Esther Walton, Ryan Muetzel, Janine F. Felix, Liesbeth Duijts, Veerle Bergink, Charlotte A.M. Cecil
Pubblicato in: Brain, Behavior, and Immunity, Numero 122, 2025, ISSN 0889-1591
Editore: Elsevier BV
DOI: 10.1016/J.BBI.2024.08.053

Developmental trajectories of gyrification and sulcal morphometrics in children and adolescents at high familial risk for bipolar disorder or schizophrenia

Autori: Simon R. Poortman, Jakub Jamarík, Louise ten Harmsen van der Beek, Nikita Setiaman, Manon H.J. Hillegers, Marjolein E.A. Barendse, Neeltje E.M. van Haren
Pubblicato in: Developmental Cognitive Neuroscience, Numero 72, 2025, ISSN 1878-9293
Editore: Elsevier BV
DOI: 10.1016/J.DCN.2025.101536

Long-term physical health conditions and youth anxiety and depression: Is there a causal link?

Autori: Amy Shakeshaft, Jessica R. Mundy, Emil M. Pedersen, Charlotte A. Dennison, Lucy Riglin, Daniela Bragantini, Elizabeth C. Corfield, Ajay K. Thapar, Ole A. Andreassen, Evie Stergiakouli, George Davey Smith, Laurie Hannigan, Katherine L. Musliner, Alexandra Havdahl, Anita Thapar
Pubblicato in: Psychological Medicine, Numero 55, 2025, ISSN 0033-2917
Editore: Cambridge University Press (CUP)
DOI: 10.1017/S0033291724003271

Cord Blood Metabolite Profiles and Their Association with Autistic Traits in Childhood

Autori: Kaupper CS, Blaauwendraad SM, Cecil CAM, Mulder RH, Gaillard R, Goncalves R, Borggraefe I, Koletzko B, Jaddoe VWV.
Pubblicato in: Metabolites, 2023, ISSN 2218-1989
Editore: Metabolites
DOI: 10.3390/metabo13111140

Comparing cognition in parents with schizophrenia or bipolar disorder and their 7-year-old offspring

Autori: Aja Neergaard Greve, Nicoline Hemager, Erik Lykke Mortensen, Ditte Lou Gantriis, Birgitte Klee Burton, Ditte Ellersgaard, Kerstin J. Plessen, Anne A.E. Thorup, Jens Richardt Møllegaard Jepsen, Merete Nordentoft, Ole Mors, Arndis Simonsen
Pubblicato in: Psychiatry Research, Numero 340, 2024, ISSN 0165-1781
Editore: Elsevier BV
DOI: 10.1016/J.PSYCHRES.2024.116112

Debate: Child and adolescent mental health services: time to take the lead in prevention of psychosis in youth

Autori: Inmaculada Baeza, Gisela Sugranyes
Pubblicato in: Child and Adolescent Mental Health, Numero 28, 2025, ISSN 1475-357X
Editore: Wiley
DOI: 10.1111/CAMH.12679

Effects of parental characteristics on the risk of psychopathology in offspring: a 4-year follow-up study

Autori: E. De la Serna, D. Moreno, G. Sugranyes, P. Camprodon-Boadas, D. Ilzarbe, A. Bigorra, B. Mora-Maltas, I. Baeza, I. Flamarique, S. Parrilla, C. M. Díaz-Caneja, C. Moreno, R. Borras, C. Torrent, C. Garcia-Rizo, J. Castro-Fornieles
Pubblicato in: European Child & Adolescent Psychiatry, Numero 34, 2025, ISSN 1018-8827
Editore: Springer Science and Business Media LLC
DOI: 10.1007/S00787-025-02719-4

Fetal Head Growth and Head Circumference at Birth in Children of Women with Psychotic Disorders and Population-Based Controls

Autori: Lisanne A E M van Houtum, Dogukan Koc, Sterna A Grundeman, Hans J Duvekot, Hanan El Marroun, Neeltje E M van Haren, Hilmar H Bijma
Pubblicato in: Schizophrenia Bulletin, 2025, ISSN 0586-7614
Editore: Oxford University Press (OUP)
DOI: 10.1093/SCHBUL/SBAF171

The Genetic Architecture of Differentiating Behavioral and Emotional Problems in Early Life

Autori: Adrian Dahl Askelund, Laura Hegemann, Andrea G. Allegrini, Elizabeth C. Corfield, Helga Ask, Neil M. Davies, Ole A. Andreassen, Alexandra Havdahl, Laurie J. Hannigan
Pubblicato in: Biological Psychiatry, Numero 97, 2025, ISSN 0006-3223
Editore: Elsevier BV
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Age Trajectories of the Structural Connectome in Child and Adolescent Offspring of Individuals With Bipolar Disorder or Schizophrenia

Autori: Simon R. Poortman, Marjolein E.A. Barendse, Nikita Setiaman, Martijn P. van den Heuvel, Siemon C. de Lange, Manon H.J. Hillegers, Neeltje E.M. van Haren
Pubblicato in: Biological Psychiatry Global Open Science, Numero 4, 2024, ISSN 2667-1743
Editore: Elsevier BV
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Gestational epigenetic age and ADHD symptoms in childhood: a prospective, multi-cohort study

Autori: Kristina Salontaji, Kristine L. Haftorn, Faye Sanders, Christian M. Page, Esther Walton, Janine F. Felix, Mona Bekkhus, Jon Bohlin, Henning Tiemeier, Charlotte A. M. Cecil
Pubblicato in: Molecular Psychiatry, Numero 29, 2024, ISSN 1359-4184
Editore: Springer Science and Business Media LLC
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Transgenerational effects of early life stress on the fecal microbiota in mice

Autori: Nize Otaru, Lola Kourouma, Benoit Pugin, Florentin Constancias, Christian Braegger, Isabelle M. Mansuy, Christophe Lacroix
Pubblicato in: Communications Biology, Numero 7, 2024, ISSN 2399-3642
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S42003-024-06279-2

Intergenerational transmission of polygenic predisposition for neuropsychiatric traits on emotional and behavioural difficulties in childhood

Autori: A. G. Allegrini, L. J. Hannigan, L. Frach, W. Barkhuizen, J. R. Baldwin, O. A. Andreassen, D. Bragantini, L. Hegemann, A. Havdahl, J-B. Pingault
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-57694-W

The epigenome under pressure: On regulatory adaptation to chronic stress in the brain.

Autori: Arzate-Mejia RG, Carullo NVN, Mansuy IM.
Pubblicato in: Current Opinion in Neurobiology, 2023, ISSN 0959-4388
Editore: Current Opinion in Neurobiology
DOI: 10.1016/J.CONB.2023.102832

Neurobiology and systems biology of stress resilience

Autori: Raffael Kalisch, Scott J. Russo, Marianne B. Müller
Pubblicato in: Physiological Reviews, Numero 104, 2024, ISSN 0031-9333
Editore: American Physiological Society
DOI: 10.1152/PHYSREV.00042.2023

Early detection and intervention through the lens of the neurodevelopmental framework: the salience of developmental years and related services

Autori: Andrea Raballo, Michele Poletti, Antonio Preti
Pubblicato in: The British Journal of Psychiatry, Numero 225, 2024, ISSN 0007-1250
Editore: Royal College of Psychiatrists
DOI: 10.1192/BJP.2024.146

Environmental and Genetic Influences on Developmental Outcomes Across the Domains of Language, Cognition, Motor Function, and Social Behavior

Autori: Marta Schiavon, Birgitte K. Burton, Nicoline Hemager, Aja N. Greve, Katrine S. Spang, Ditte Ellersgaard, Kerstin Jessica Plessen, Jens Richardt M. Jepsen, Anne A. E. Thorup, Thomas Werge, Merete Nordentoft, Ron Nudel
Pubblicato in: European Journal of Neuroscience, Numero 61, 2025, ISSN 0953-816X
Editore: Wiley
DOI: 10.1111/EJN.70163

Evocative effects of children's education‐associated genetics on maternal parenting: results from the Norwegian mother, father and child cohort study

Autori: Chloe Austerberry, Tetyana Zayats, Angelica Ronald, Elizabeth Corfield, Dinka Smajlagic, Alexandra Havdahl, Ole A. Andreassen, Per Magnus, Pål R. Njølstad, Mona Bekkhus, Pasco Fearon
Pubblicato in: Journal of Child Psychology and Psychiatry, 2025, ISSN 0021-9630
Editore: Wiley
DOI: 10.1111/JCPP.70025

The effect of age and sex on brain metabolites: from childhood to adulthood

Autori: María Ortuño, Adriana Fortea, Isabel Valli, Emma Muñoz-Moreno, Roger Borràs, Irene Martínez-Serrano, Mireia Masias Bruns, Patricia Camprodon-Boadas, Enric Vilajosana, Lydia Fortea, Joaquim Raduà, Elena de la Serna, Inmaculada Baeza, Josefina Castro-Fornieles, Gisela Sugranyes
Pubblicato in: NeuroImage, Numero 317, 2025, ISSN 1053-8119
Editore: Elsevier BV
DOI: 10.1016/J.NEUROIMAGE.2025.121353

Assessing risk for bipolar disorder. Comments on ``Young people at risk for developing bipolar disorder: Two-year findings from the multicenter prospective, naturalistic Early-BipoLife study'' (Martini et al., 2023)

Autori: Mireia Solerdelcoll, Inmaculada Baeza, Gisela Sugranyes
Pubblicato in: European Neuropsychopharmacology, Numero 81, 2025, ISSN 0924-977X
Editore: Elsevier BV
DOI: 10.1016/J.EURONEURO.2024.01.001

The bidirectional relationship between brain structure and physical activity: A longitudinal analysis in the UK Biobank

Autori: Rodriguez-Ayllon M, Neumann A, Hofman A, Vernooij MW, Neitzel J.
Pubblicato in: Neurobiology of Aging, 2024, ISSN 0197-4580
Editore: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2024.03.001

Testing maternal effects of vitamin-D and omega-3 levels on offspring neurodevelopmental traits in the Norwegian Mother, Father and Child Cohort Study

Autori: Robyn E. Wootton, Kyle Dack, Hannah J. Jones, Lucy Riglin, Paul Madley-Dowd, Carolina Borges, Panagiota Pagoni, Christine Roth, Anne Lise Brantsæter, Elizabeth C. Corfield, Camilla Stoltenberg, Anne-Siri Øyen, George Davey Smith, Helga Ask, Anita Thapar, Evie Stergiakouli, Alexandra Havdahl
Pubblicato in: Psychological Medicine, Numero 54, 2025, ISSN 0033-2917
Editore: Cambridge University Press (CUP)
DOI: 10.1017/S0033291724001466

Prenatal exposure to adverse life events and autism and autistic‐like traits in children in the Norwegian Mother, Father and Child Cohort Study (MoBa)

Autori: Aleksandra Kanina, Arvid Sjölander, Miriam I. Martini, Agnieszka Butwicka, Henrik Larsson, Amanda M. Hughes, Márta K. Radó, Mark J. Taylor, Alexandra Havdahl, Helga Ask, Mina A. Rosenqvist
Pubblicato in: JCPP Advances, 2025, ISSN 2692-9384
Editore: Wiley
DOI: 10.1002/JCV2.70002

Biological pathways underlying the relationship between childhood maltreatment and Multimorbidity: A two-step, multivariable Mendelian randomisation study

Autori: Vilte Baltramonaityte, Ville Karhunen, Janine F. Felix, Brenda W.J.H. Penninx, Charlotte A.M. Cecil, Graeme Fairchild, Yuri Milaneschi, Esther Walton
Pubblicato in: Brain, Behavior, and Immunity, Numero 126, 2025, ISSN 0889-1591
Editore: Elsevier BV
DOI: 10.1016/J.BBI.2025.01.024

Neurobiology and systems biology of stress resilience.

Autori: Kalisch R, Russo SJ, Müller MB.
Pubblicato in: Physiological Reviews, 2023, ISSN 0031-9333
Editore: Physiological Reviews
DOI: 10.1152/PHYSREV.00042.2023

Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.

Autori: Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, Blin O, Richardson JC, Bordet R, Lleó A, Alcolea D, Popp J, Marsh TW, Gorijala
Pubblicato in: Genome Medicine volume, 2023, ISSN 1756-994X
Editore: Genome Medicine volume
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Are different types of childhood adversities correlated within and across time? A comparison of data on adversity co-occurrence from three longitudinal birth cohort studies

Autori: Madison E. Bigler, Isabel K. Schuurmans, Yiwen Zhu, Nitasha Siddique, Nadia Hoffman, Nastassja Koen, Heather J. Zar, Dan J. Stein, Charlotte A.M. Cecil, Erin C. Dunn
Pubblicato in: Child Abuse & Neglect, Numero 168, 2025, ISSN 0145-2134
Editore: Elsevier BV
DOI: 10.1016/J.CHIABU.2025.107315

Youth psychotic experiences: psychometric evaluation and diagnostic associations of the <scp>CAPE</scp> ‐16 in adolescents from the Norwegian Mother, Father and Child Cohort

Autori: Viktoria Birkenæs, Pravesh Parekh, Laura Hegemann, Nora R. Bakken, Evgeniia Frei, Piotr Jaholkowski, Olav B. Smeland, Ezra Susser, Katrina M. Rodriguez, Markos Tesfaye, Ole A. Andreassen, Alexandra Havdahl, Ida E. Sønderby
Pubblicato in: Journal of Child Psychology and Psychiatry, 2025, ISSN 0021-9630
Editore: Wiley
DOI: 10.1111/JCPP.70007

Parental education and children’s depression, anxiety, and ADHD traits, a within-family study in MoBa

Autori: Amanda M. Hughes, Fartein Ask Torvik, Elsje van Bergen, Laurie J. Hannigan, Elizabeth C. Corfield, Ole A. Andreassen, Eivind Ystrom, Helga Ask, George Davey Smith, Neil M. Davies, Alexandra Havdahl
Pubblicato in: npj Science of Learning, Numero 9, 2024, ISSN 2056-7936
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41539-024-00260-8

Characterising developmental dynamics of adult epigenetic clock sites

Autori: Rosa H. Mulder, Alexander Neumann, Janine F. Felix, Matthew Suderman, Charlotte A.M. Cecil
Pubblicato in: eBioMedicine, Numero 109, 2024, ISSN 2352-3964
Editore: Elsevier BV
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Remembering through the genome: the role of chromatin states in brain functions and diseases

Autori: Arzate-Mejia RG, Mansuy IM.
Pubblicato in: Translational Psychiatry, Numero 122, 2023, ISSN 2158-3188
Editore: Translational Psychiatry
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Dynastic social processes and the transgenerational transmission of risk and resilience to mental illness: implications for prevention

Autori: Andrea Raballo, Michele Poletti, Antonio Preti
Pubblicato in: European Child & Adolescent Psychiatry, Numero 34, 2025, ISSN 1018-8827
Editore: Springer Science and Business Media LLC
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Genetic liability to major psychiatric disorders contributes to multi-faceted quality of life outcomes in children and adults

Autori: Yingjie Shi, Nina Roth Mota, Barbara Franke, Emma Sprooten
Pubblicato in: Translational Psychiatry, Numero 15, 2025, ISSN 2158-3188
Editore: Springer Science and Business Media LLC
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The role of lifestyle factors in the association between early-life stress and adolescent psycho-physical health: Moderation analysis in two European birth cohorts

Autori: Serena Defina, Tom Woofenden, Vilte Baltramonaityte, Henning Tiemeier, Graeme Fairchild, Janine F. Felix, Charlotte A.M. Cecil, Esther Walton
Pubblicato in: Preventive Medicine, Numero 182, 2025, ISSN 0091-7435
Editore: Elsevier BV
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Running in the FAMILY - Understanding and predicting the intergenerational transmission of mental illness

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