Running in the FAMILY - Understanding and predicting the intergenerational transmission of mental illness

Informazioni relative al progetto

FAMILY

ID dell’accordo di sovvenzione: 101057529

DOI

10.3030/101057529

Data della firma CE 24 Maggio 2022

Data di avvio 1 Ottobre 2022

Data di completamento 30 Settembre 2027

Finanziato da

• Health

Costo totale

€ 10 906 409,75

Contributo UE

€ 10 906 409,75

Coordinato da

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (7)

1st version of data management, harmonisation, and open science plan
Report on the software pipelines based on simulation studies
Training plan
Marketing materials
1st report and plan for gender balance
Dissemination and Communication plan
Report on relevant outside initiatives and activities in the field and plan for collaboration

Other (2)

Registration numbers of the clinical studies (WHO Registry criteria)
Ethics institutional approvals

Websites, patent fillings, videos etc. (1)

Go-online of the public project website

Pubblicazioni

Peer reviewed articles (17)

Epigenetics applied to child and adolescent mental health: Progress, challenges and opportunities

Autori: Charlotte A. M. Cecil, Alexander Neumann, Esther Walto
Pubblicato in: JCPP Advances, Numero 3, 1, 2023, ISSN 2692-9384
Editore: CPP Advances Volume 3, Issue 1
DOI: 10.1186/s13073-023-01233-z

Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development

Autori: Hughes DE, Kunitoki K, Elyounssi S, Luo M, Bazer OM, Hopkinson CE, Dowling KF, Doyle AE, Dunn EC, Eryilmaz H, Gilman JM, Holt DJ, Valera EM, Smoller JW, Cecil CAM, Tiemeier H, Lee PH, Roffman JL.
Pubblicato in: Nature Neuroscience, Numero 26, 2023, ISSN 1546-1726
Editore: Nature Neuroscience
DOI: 10.1038/s41593-023-01321-8

Early-life stress and the gut microbiome: A comprehensive population-based investigation

Autori: Mulder RH, Kraaij R, Schuurmans IK, Frances-Cuesta C, Sanz Y, Medina-Gomez C, Duijts L, Rivadeneira F, Tiemeier H, Jaddoe VWV, Felix JF, Cecil CAM.
Pubblicato in: Brain, Behavior, and Immunity, 2024, ISSN 0889-1591
Editore: Brain, Behavior, and Immunity
DOI: 10.1016/j.bbi.2024.02.024

A systematic review of neuroimaging epigenetic research: calling for an increased focus on development

Autori: Walton E, Baltramonaityte V, Calhoun V, Heijmans BT, Thompson PM, Cecil CAM.
Pubblicato in: Molecular Psychiatry, Numero 28, 2023, ISSN 1476-5578
Editore: Molecular Psychiatry
DOI: 10.1038/s41380-023-02067-2

Exposure to prenatal infection and the developmentof internalizing and externalizing problems inchildren: a longitudinal population-based study

Autori: Suleri A, Rommel AS, Neumann A, Luo M, Hillegers M, de Witte L, Bergink V, Cecil CAM.
Pubblicato in: Journal of Child Psychology and Psychiatry, 2024, ISSN 1469-7610
Editore: Journal of Child Psychology and Psychiatry
DOI: 10.1111/jcpp.13923

Principal and independent genomic components of brain structure and function

Autori: Oblong LM,Soheili-Nezhad S, Trevisan N, Shi Y, Beckmann CF, Sprooten E
Pubblicato in: Genes, Brain and Behavior, 2024, ISSN 1601-183X
Editore: Genes, Brain and Behavior
DOI: 10.1111/gbb.12876

Risk factors for mood disorders among offspring of parents with bipolar disorder: Findings from a discordant-sibling study

Autori: Giacomo FD, Strippoli MF, Castelao E, Amoussou JR, Gholam M, Ranjbar S, Glaus J, Marquet P, Preisig M, Plessen KJ, Vandeleur CL.
Pubblicato in: Psychiatry Research, 2023, ISSN 0165-1781
Editore: Psychiatry Research
DOI: 10.1016/j.psychres.2023.115615

On Navigating Analytical Choices in Research on Early Life Adversity: A Commentary on Sisitsky et al. (2023).

Autori: Cecil CAM, Schuurmans IK. 
Pubblicato in: Research on Child and Adolescent Psychopathology, 2023, ISSN 2730-7174
Editore: Research on Child and Adolescent Psychopathology
DOI: 10.1007/S10802-023-01103-7

DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study.

Autori: Luo M, Walton E, Neumann A, Thio CHL, Felix JF, van IJzendoorn MH, Pappa I, Cecil CAM. 
Pubblicato in: Journal of Child Psychology and Psychiatry, 2024, ISSN 0021-9630
Editore: Journal of Child Psychology and Psychiatry
DOI: 10.1111/JCPP.13866

The role of lifestyle factors in the association between early-life stress and adolescent psycho-physical health: Moderation analysis in two European birth cohorts

Autori: Defina S, Woofenden T, Baltramonaityte V, Tiemeier H, Fairchild G, Felix JF, Cecil CAM, Walton E.
Pubblicato in: Preventive Medicine, 2024, ISSN 0091-7435
Editore: Preventive Medicine
DOI: 10.1016/j.ypmed.2024.107926

Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

Autori: Lazar-Contes I, Tanwar DK, Arzate-Meija RG, Steg LC, Feudijo OU, Crespo M, Germain PL, Mansuy IM
Pubblicato in: Genetics and Genomics, 2023, ISSN 2050-084X
Editore: eLife
DOI: 10.7554/eLife.91528.1

Cord Blood Metabolite Profiles and Their Association with Autistic Traits in Childhood

Autori: Kaupper CS, Blaauwendraad SM, Cecil CAM, Mulder RH, Gaillard R, Goncalves R, Borggraefe I, Koletzko B, Jaddoe VWV.
Pubblicato in: Metabolites, 2023, ISSN 2218-1989
Editore: Metabolites
DOI: 10.3390/metabo13111140

The epigenome under pressure: On regulatory adaptation to chronic stress in the brain. 

Autori: Arzate-Mejia RG, Carullo NVN, Mansuy IM.
Pubblicato in: Current Opinion in Neurobiology, 2023, ISSN 0959-4388
Editore: Current Opinion in Neurobiology
DOI: 10.1016/J.CONB.2023.102832

The bidirectional relationship between brain structure and physical activity: A longitudinal analysis in the UK Biobank

Autori: Rodriguez-Ayllon M, Neumann A, Hofman A, Vernooij MW, Neitzel J.
Pubblicato in: Neurobiology of Aging, 2024, ISSN 0197-4580
Editore: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2024.03.001

Neurobiology and systems biology of stress resilience. 

Autori: Kalisch R, Russo SJ, Müller MB.
Pubblicato in: Physiological Reviews, 2023, ISSN 0031-9333
Editore: Physiological Reviews
DOI: 10.1152/PHYSREV.00042.2023

Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.

Autori: Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, Blin O, Richardson JC, Bordet R, Lleó A, Alcolea D, Popp J, Marsh TW, Gorijala
Pubblicato in: Genome Medicine volume, 2023, ISSN 1756-994X
Editore: Genome Medicine volume
DOI: 10.1186/s13073-023-01233-z

Remembering through the genome: the role of chromatin states in brain functions and diseases

Autori: Arzate-Mejia RG, Mansuy IM.
Pubblicato in: Translational Psychiatry, Numero 122, 2023, ISSN 2158-3188
Editore: Translational Psychiatry
DOI: 10.1038/s41398-023-02415-4