Epigenetic regulation of host factors in viral infections (EPIVINF)

Informazioni relative al progetto

EPIVINF

ID dell’accordo di sovvenzione: 101057548

DOI

10.3030/101057548

Data della firma CE 23 Maggio 2022

Data di avvio 1 Settembre 2022

Data di completamento 31 Agosto 2027

Finanziato da

• Health

Costo totale

€ 6 932 308,75

Contributo UE

€ 6 932 308,00

Coordinato da

FUNDACIO PRIVADA INSTITUT DE RECERCA SOBRE IMMUNOPATOLOGIES-CAIXA, IRSICAIXA
Spain

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (8)

Project Handbook on Management
Data management plan - update

Updated data management plan.

Dissemination and communication plan - update 1

Dissemination and communication plan

Data management Plan

DMP structured according to the Horizon Europe DMP template

List of epigenetic markers predictive of viral load (HIV) and disease course (COVID)
Dissemination and communication plan
Result summary on Sirtuins abundancy and functionality in HIV and SARS-CoV-2 infected patients
Report on the RRI activities performed within the project

Websites, patent fillings, videos etc. (1)

Project website

The website will have two different sections: i) A Public section, which will contain a description of objectives, structure, consortium, agenda, pictures, templates etc. ii) a Private section, which is only accessible to the project consortium and authorised partners.

Pubblicazioni

Peer reviewed articles (9)

Mibianto: ultra-efficient online microbiome analysis through <i>k</i>-mer based metagenomics

Autori: Pascal Hirsch; Leidy-Alejandra G Molano; Annika Engel; Jens Zentgraf; Sven Rahmann; Matthias Hannig; Rolf Müller; Fabian Kern; Andreas Keller; Georges P Schmartz
Pubblicato in: Nucleic Acids Research, Numero 52, 2024, ISSN 1362-4962
Editore: Oxford University Press
DOI: 10.22028/D291-42446

Animal models to study the neurological manifestations of the post-COVID-19 condition

Autori: Carla Usai, Lourdes Mateu, Christian Brander, Júlia Vergara-Alert & Joaquim Segalés
Pubblicato in: Lab Animal, 2023, ISSN 0093-7355
Editore: Lab animal. Nature
DOI: 10.1038/s41684-023-01231-z

A single-cell atlas to map sex-specific gene-expression changes in blood upon neurodegeneration

Autori: Friederike Grandke, Tobias Fehlmann, Fabian Kern, David M. Gate, Tobias William Wolff, Olivia Leventhal, Divya Channappa, Pascal Hirsch, Edward N. Wilson, Eckart Meese, Chuanyu Liu, Quan Shi, Matthias Flotho, Yongping Li, Cynthia Chen, Yeya Yu, Jiangshan Xu, Michael Junkin, Zhifeng Wang, Tao Wu, Longqi Liu, Yong Hou, Katrin I. Andreasson, Jenny S. Gansen, Elvira Mass, Kathleen Poston, Tony Wyss-Coray, Andreas Keller
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-56833-7

Nature Communications

Autori: Jesper Gunst; Jesal Gohil; Jonathan Li; Ronald Bosch; Andrea White; Catherine Seamon; Tae-Wook Chun; Beatriz Mothe; Kathleen Gittens; Lauren Praiss; Marie-Angélique De Scheerder; Linos Vandekerckhove; Kevin Escandón; Ann Thorkelson; Timothy Schacker; Devi SenGupta; Christian Brander; Emmanouil Papasavvas; Luis Montaner; Javier Martinez-Picado; Ruxandra Calin; Antonella Castagna; Camilla Muccini; Wesley Jong; Lorna Leal; Felipe Garcia; Rob Gruters; Timothy Tipoe; John Frater; Ole Søgaard; Sarah Fidler
Pubblicato in: Nature Communications, 2025, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.21203/RS.3.RS-5065764/V1

RNA Biology

Autori: Annika Engel; Nicole Ludwig; Friederike Grandke; Viktoria Wagner; Fabian Kern; Tobias Fehlmann; Georges P. Schmartz; Ernesto Aparicio-Puerta; Dominic Henn; Barbara Walch-Rückheim; Matthias Hannig; Stefan Rupf; Eckart Meese; Matthias W. Laschke; Andreas Keller
Pubblicato in: RNA Biology, 2024, ISSN 1547-6286
Editore: Informa UK Limited
DOI: 10.22028/D291-42453

SingmiR: a single-cell miRNA alignment and analysis tool

Autori: Annika Engel; Shusruto Rishik; Pascal Hirsch; Verena Keller; Tobias Fehlmann; Fabian Kern; Andreas Keller
Pubblicato in: Nucleic Acids Research, 2024, ISSN 1362-4962
Editore: Oxford University Press
DOI: 10.22028/D291-42445

Sirtuin-2, NAD-Dependent Deacetylase, Is a New Potential Therapeutic Target for HIV-1 Infection and HIV-Related Neurological Dysfunction

Autori: Duran-Castells C, Llano A, Kawana-Tachikawa A, Prats A, Martinez-Zalacain I, Kobayashi-Ishihara M, Oriol-Tordera B, Peña R, Gálvez C, Silva-Arrieta S, Clotet B, Riveira-Muñoz E, Ballana E, Prado JG, Martinez-Picado J, Sanchez J, Mothe B, Hartigan-O'Connor
Pubblicato in: J. Virology, 2023, ISSN 1098-5514
Editore: ASM Journals
DOI: 10.1128/jvi.01655-22

Long-term neurocognitive outcomes of SARS-CoV-2 infection in a hamster model

Autori: Carla Ruiz-Casas, Ferran Tarrés-Freixas, Núria Roca, Mònica Pérez, Guillermo Cantero, Laura Martín, Alex Olvera, Marta Ruiz-Riol, Christian Brander, Carla Usai, Júlia Vergara-Alert, Joaquim Segalés
Pubblicato in: Frontiers in Microbiology, Numero 16, 2025, ISSN 1664-302X
Editore: Frontiers Media SA
DOI: 10.3389/FMICB.2025.1646616

Plasma proteomic profiling identifies CD33 as a marker of HIV control in natural infection and after therapeutic vaccination

Autori: Clara Duran-Castells, Anna Prats, Bruna Oriol-Tordera, Anuska Llano, Cristina Galvez, Javier Martinez-Picado, Ester Ballana, Edurne Garcia-Vidal, Bonaventura Clotet, Jose A. Muñoz-Moreno, Thomas Hanke, José Moltó, Beatriz Mothe, Christian Brander, Marta Ruiz-Riol
Pubblicato in: eBioMedicine, Numero 95, 2023, ISSN 2352-3964
Editore: Elsevier BV
DOI: 10.1016/J.EBIOM.2023.104732