Boosting the reduction of the environmental impact of pharmaceutical products throughout their entire life cycle.

Información del proyecto

ETERNAL

Identificador del acuerdo de subvención: 101057668

DOI

10.3030/101057668

Fecha de la firma de la CE 23 Mayo 2022

Fecha de inicio 1 Septiembre 2022

Fecha de finalización 31 Agosto 2026

Financiado con arreglo a

• Health

Coste total

€ 5 922 398,75

Aportación de la UE

€ 5 922 396,00

Coordinado por

AIMPLAS - ASOCIACION DE INVESTIGACION DE MATERIALES PLASTICOS Y CONEXAS
Spain

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (5)

Report on the standardization landscape and applicable standards

Report summarizing the relevant standardization landscape and appliable standards

Roadmap for adoption of PAT and Digital Twin Technologies (including regulatory compliance requirements)

Report that will consist in a summary review of SoA of PAT and Digital Twin adoption in European Pharmaceutical industry; a SWOT analysis to feed into an Opportunities Roadmap that also takes account of the regulatory hurdles, as well as recommendations for a favorable/enabling regulatory framework, without compromising safety.

"Concept paper on ""compliance-by-design"" key-drivers and roadmap of the possible regulatory pathways or relevant regulatory frameworks for the required ""compliance-by-design"" strategies"

Concept paper that reviews the latest developments in the scientific review, regulation, and marketing authorization procedures in the respective fields (related to the ETERNAL technological processes and developments) to inform a ‘compliant-by-design’ strategy in relation to the developments as part of the ETERNAL cocreation process.

Report on the contribution to standardization

Report outlining the contribution the project has/will make to standards.

Research roadmap and inventory of tools for the integration of existing knowledge into pharma risk assessment

Public report that documents a research roadmap for the integration of scientific and regulatory knowledge into pharmaceutical risk assessment for fate modelling, bioavailability assessment and receptor identification, for regulatory testing and assessment, and inventory of tools for the integration of existing knowledge into pharma risk assessment.

Websites, patent fillings, videos etc. (1)

Project website

Project website.

Publicaciones

Peer reviewed articles (5)

A framework for early-stage sustainability assessment of innovation projects enabled by weighted sum multi-criteria decision analysis in the presence of uncertainty

Autores: John Henderson; Robert Peeling
Publicado en: Open Research Europe, 2024, ISSN 2732-5121
Editor: Open Research Europe
DOI: 10.12688/OPENRESEUROPE.18195.1

Recovery and reuse of homogeneous palladium catalysts <i>via</i> organic solvent nanofiltration: application in the synthesis of AZD4625

Autores: Hui Xiao; William R. F. Goundry; Rhys Griffiths; Yanyue Feng; Staffan Karlsson
Publicado en: Green Chemistry, 2025, ISSN 1463-9270
Editor: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4GC06334A

Environmental Toxicology

Autores: Fábio Campos; Maria D. Pavlaki; Amadeu M. V. M. Soares; Susana Loureiro
Publicado en: Environmental Toxicology, 2025, ISSN 1520-4081
Editor: John Wiley & Sons Inc.
DOI: 10.1002/TOX.70002

Continuous improvement towards environmental protection for pharmaceuticals: advancing a strategy for Europe

Autores: Sam Harrison, Catherine Barnett, Stephen Short, Cansu Uluseker, Patricia V. Silva, Maria D. Pavlaki, Sarah Roberts, Madalena Vieira, Stephen Lofts, Susana Loureiro, David J. Spurgeon
Publicado en: Environmental Sciences Europe, Edición 37, 2025, ISSN 2190-4715
Editor: Springer Science and Business Media LLC
DOI: 10.1186/S12302-025-01180-Z

Organic Solvent Nanofiltration in Pharmaceutical Applications

Autores: Xiaoa, Hui; Feng, Yanyue; Goundry, William R.F.; Karlsson, Staffan
Publicado en: Organic Process Research and Development, 2024, ISSN 0000-0000
Editor: American Chemical Society
DOI: 10.1021/acs.oprd.3c00470

Conference proceedings (6)

Project Eternal Overview Presentation

Autores: Ferrer Pérez, Pablo; Sebastia-Luna, Paz; Henderson, John
Publicado en: 2025
Editor: ZENODO
DOI: 10.5281/ZENODO.10688671

Workshop Output report from an ETERNAL Industry engagement workshop at Making Pharmaceuticals UK Conference programme. Making Pharmaceuticals UK Conference, Coventry, United Kingdom.

Autores: Henderson, J.
Publicado en: Zenodo, 2024
Editor: Zenodo
DOI: 10.5281/ZENODO.12745018

SETAC_Pharmaceuticals Strategy for Europe A Call for Continuous Improvement towards Environmental Protection

Autores: Sam Harrison
Publicado en: SETAC Europe 34th Annual Meeting (SETAC), Seville, 2025
Editor: SPRINGER
DOI: 10.1186/s12302-025-01180-z

Assessing the feasibility of Twin Screw Extrusion processing in the development of pharmaceutical products

Autores: Ficiarà, E.
Publicado en: 2024
Editor: Zenodo
DOI: 10.5281/ZENODO.15114844

A New Collaboration to Establish Safe and Sustainable Pharmaceutical Lifecycles by Design

Autores: Henderson, John; Peeling Robert
Publicado en: 2025
DOI: 10.5281/zenodo.10788903

Optimized used of solvents in Active Pharmaceutical Ingredients production

Autores: Iacoangeli, T.
Publicado en: 2024
Editor: Zenodo
DOI: 10.5281/ZENODO.15114540

Other (1)

"Concept paper on ""compliant-by-design"" key-drivers and roadmap of the possible regulatory pathways or relevant regulatory frameworks for the required ""compliant-by-design"" strategies"

Autores: Diego Hernandez Pedraza
Publicado en: 2023
Editor: 00000
DOI: 10.5281/ZENODO.12795163