Boosting the reduction of the environmental impact of pharmaceutical products throughout their entire life cycle.

Informations projet

ETERNAL

N° de convention de subvention: 101057668

DOI

10.3030/101057668

Date de signature de la CE 23 Mai 2022

Date de début 1 Septembre 2022

Date de fin 31 Août 2026

Financé au titre de

• Health

Coût total

€ 5 922 398,75

Contribution de l’UE

€ 5 922 396,00

Coordonné par

AIMPLAS - ASOCIACION DE INVESTIGACION DE MATERIALES PLASTICOS Y CONEXAS
Spain

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (5)

Report on the standardization landscape and applicable standards

Report summarizing the relevant standardization landscape and appliable standards

Roadmap for adoption of PAT and Digital Twin Technologies (including regulatory compliance requirements)

Report that will consist in a summary review of SoA of PAT and Digital Twin adoption in European Pharmaceutical industry; a SWOT analysis to feed into an Opportunities Roadmap that also takes account of the regulatory hurdles, as well as recommendations for a favorable/enabling regulatory framework, without compromising safety.

"Concept paper on ""compliance-by-design"" key-drivers and roadmap of the possible regulatory pathways or relevant regulatory frameworks for the required ""compliance-by-design"" strategies"

Concept paper that reviews the latest developments in the scientific review, regulation, and marketing authorization procedures in the respective fields (related to the ETERNAL technological processes and developments) to inform a ‘compliant-by-design’ strategy in relation to the developments as part of the ETERNAL cocreation process.

Report on the contribution to standardization

Report outlining the contribution the project has/will make to standards.

Research roadmap and inventory of tools for the integration of existing knowledge into pharma risk assessment

Public report that documents a research roadmap for the integration of scientific and regulatory knowledge into pharmaceutical risk assessment for fate modelling, bioavailability assessment and receptor identification, for regulatory testing and assessment, and inventory of tools for the integration of existing knowledge into pharma risk assessment.

Websites, patent fillings, videos etc. (1)

Project website

Project website.

Publications

Peer reviewed articles (5)

A framework for early-stage sustainability assessment of innovation projects enabled by weighted sum multi-criteria decision analysis in the presence of uncertainty

Auteurs: John Henderson; Robert Peeling
Publié dans: Open Research Europe, 2024, ISSN 2732-5121
Éditeur: Open Research Europe
DOI: 10.12688/OPENRESEUROPE.18195.1

Recovery and reuse of homogeneous palladium catalysts <i>via</i> organic solvent nanofiltration: application in the synthesis of AZD4625

Auteurs: Hui Xiao; William R. F. Goundry; Rhys Griffiths; Yanyue Feng; Staffan Karlsson
Publié dans: Green Chemistry, 2025, ISSN 1463-9270
Éditeur: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4GC06334A

Environmental Toxicology

Auteurs: Fábio Campos; Maria D. Pavlaki; Amadeu M. V. M. Soares; Susana Loureiro
Publié dans: Environmental Toxicology, 2025, ISSN 1520-4081
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/TOX.70002

Continuous improvement towards environmental protection for pharmaceuticals: advancing a strategy for Europe

Auteurs: Sam Harrison, Catherine Barnett, Stephen Short, Cansu Uluseker, Patricia V. Silva, Maria D. Pavlaki, Sarah Roberts, Madalena Vieira, Stephen Lofts, Susana Loureiro, David J. Spurgeon
Publié dans: Environmental Sciences Europe, Numéro 37, 2025, ISSN 2190-4715
Éditeur: Springer Science and Business Media LLC
DOI: 10.1186/S12302-025-01180-Z

Organic Solvent Nanofiltration in Pharmaceutical Applications

Auteurs: Xiaoa, Hui; Feng, Yanyue; Goundry, William R.F.; Karlsson, Staffan
Publié dans: Organic Process Research and Development, 2024, ISSN 0000-0000
Éditeur: American Chemical Society
DOI: 10.1021/acs.oprd.3c00470

Conference proceedings (6)

Project Eternal Overview Presentation

Auteurs: Ferrer Pérez, Pablo; Sebastia-Luna, Paz; Henderson, John
Publié dans: 2025
Éditeur: ZENODO
DOI: 10.5281/ZENODO.10688671

Workshop Output report from an ETERNAL Industry engagement workshop at Making Pharmaceuticals UK Conference programme. Making Pharmaceuticals UK Conference, Coventry, United Kingdom.

Auteurs: Henderson, J.
Publié dans: Zenodo, 2024
Éditeur: Zenodo
DOI: 10.5281/ZENODO.12745018

SETAC_Pharmaceuticals Strategy for Europe A Call for Continuous Improvement towards Environmental Protection

Auteurs: Sam Harrison
Publié dans: SETAC Europe 34th Annual Meeting (SETAC), Seville, 2025
Éditeur: SPRINGER
DOI: 10.1186/s12302-025-01180-z

Assessing the feasibility of Twin Screw Extrusion processing in the development of pharmaceutical products

Auteurs: Ficiarà, E.
Publié dans: 2024
Éditeur: Zenodo
DOI: 10.5281/ZENODO.15114844

A New Collaboration to Establish Safe and Sustainable Pharmaceutical Lifecycles by Design

Auteurs: Henderson, John; Peeling Robert
Publié dans: 2025
DOI: 10.5281/zenodo.10788903

Optimized used of solvents in Active Pharmaceutical Ingredients production

Auteurs: Iacoangeli, T.
Publié dans: 2024
Éditeur: Zenodo
DOI: 10.5281/ZENODO.15114540

Other (1)

"Concept paper on ""compliant-by-design"" key-drivers and roadmap of the possible regulatory pathways or relevant regulatory frameworks for the required ""compliant-by-design"" strategies"

Auteurs: Diego Hernandez Pedraza
Publié dans: 2023
Éditeur: 00000
DOI: 10.5281/ZENODO.12795163