Boosting the reduction of the environmental impact of pharmaceutical products throughout their entire life cycle.

Informazioni relative al progetto

ETERNAL

ID dell’accordo di sovvenzione: 101057668

DOI

10.3030/101057668

Data della firma CE 23 Maggio 2022

Data di avvio 1 Settembre 2022

Data di completamento 31 Agosto 2026

Finanziato da

• Health

Costo totale

€ 5 922 398,75

Contributo UE

€ 5 922 396,00

Coordinato da

AIMPLAS - ASOCIACION DE INVESTIGACION DE MATERIALES PLASTICOS Y CONEXAS
Spain

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (5)

Report on the standardization landscape and applicable standards

Report summarizing the relevant standardization landscape and appliable standards

Roadmap for adoption of PAT and Digital Twin Technologies (including regulatory compliance requirements)

Report that will consist in a summary review of SoA of PAT and Digital Twin adoption in European Pharmaceutical industry; a SWOT analysis to feed into an Opportunities Roadmap that also takes account of the regulatory hurdles, as well as recommendations for a favorable/enabling regulatory framework, without compromising safety.

"Concept paper on ""compliance-by-design"" key-drivers and roadmap of the possible regulatory pathways or relevant regulatory frameworks for the required ""compliance-by-design"" strategies"

Concept paper that reviews the latest developments in the scientific review, regulation, and marketing authorization procedures in the respective fields (related to the ETERNAL technological processes and developments) to inform a ‘compliant-by-design’ strategy in relation to the developments as part of the ETERNAL cocreation process.

Report on the contribution to standardization

Report outlining the contribution the project has/will make to standards.

Research roadmap and inventory of tools for the integration of existing knowledge into pharma risk assessment

Public report that documents a research roadmap for the integration of scientific and regulatory knowledge into pharmaceutical risk assessment for fate modelling, bioavailability assessment and receptor identification, for regulatory testing and assessment, and inventory of tools for the integration of existing knowledge into pharma risk assessment.

Websites, patent fillings, videos etc. (1)

Project website

Project website.

Pubblicazioni

Peer reviewed articles (5)

A framework for early-stage sustainability assessment of innovation projects enabled by weighted sum multi-criteria decision analysis in the presence of uncertainty

Autori: John Henderson; Robert Peeling
Pubblicato in: Open Research Europe, 2024, ISSN 2732-5121
Editore: Open Research Europe
DOI: 10.12688/OPENRESEUROPE.18195.1

Recovery and reuse of homogeneous palladium catalysts <i>via</i> organic solvent nanofiltration: application in the synthesis of AZD4625

Autori: Hui Xiao; William R. F. Goundry; Rhys Griffiths; Yanyue Feng; Staffan Karlsson
Pubblicato in: Green Chemistry, 2025, ISSN 1463-9270
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4GC06334A

Environmental Toxicology

Autori: Fábio Campos; Maria D. Pavlaki; Amadeu M. V. M. Soares; Susana Loureiro
Pubblicato in: Environmental Toxicology, 2025, ISSN 1520-4081
Editore: John Wiley & Sons Inc.
DOI: 10.1002/TOX.70002

Continuous improvement towards environmental protection for pharmaceuticals: advancing a strategy for Europe

Autori: Sam Harrison, Catherine Barnett, Stephen Short, Cansu Uluseker, Patricia V. Silva, Maria D. Pavlaki, Sarah Roberts, Madalena Vieira, Stephen Lofts, Susana Loureiro, David J. Spurgeon
Pubblicato in: Environmental Sciences Europe, Numero 37, 2025, ISSN 2190-4715
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S12302-025-01180-Z

Organic Solvent Nanofiltration in Pharmaceutical Applications

Autori: Xiaoa, Hui; Feng, Yanyue; Goundry, William R.F.; Karlsson, Staffan
Pubblicato in: Organic Process Research and Development, 2024, ISSN 0000-0000
Editore: American Chemical Society
DOI: 10.1021/acs.oprd.3c00470

Conference proceedings (6)

Project Eternal Overview Presentation

Autori: Ferrer Pérez, Pablo; Sebastia-Luna, Paz; Henderson, John
Pubblicato in: 2025
Editore: ZENODO
DOI: 10.5281/ZENODO.10688671

Workshop Output report from an ETERNAL Industry engagement workshop at Making Pharmaceuticals UK Conference programme. Making Pharmaceuticals UK Conference, Coventry, United Kingdom.

Autori: Henderson, J.
Pubblicato in: Zenodo, 2024
Editore: Zenodo
DOI: 10.5281/ZENODO.12745018

SETAC_Pharmaceuticals Strategy for Europe A Call for Continuous Improvement towards Environmental Protection

Autori: Sam Harrison
Pubblicato in: SETAC Europe 34th Annual Meeting (SETAC), Seville, 2025
Editore: SPRINGER
DOI: 10.1186/s12302-025-01180-z

Assessing the feasibility of Twin Screw Extrusion processing in the development of pharmaceutical products

Autori: Ficiarà, E.
Pubblicato in: 2024
Editore: Zenodo
DOI: 10.5281/ZENODO.15114844

A New Collaboration to Establish Safe and Sustainable Pharmaceutical Lifecycles by Design

Autori: Henderson, John; Peeling Robert
Pubblicato in: 2025
DOI: 10.5281/zenodo.10788903

Optimized used of solvents in Active Pharmaceutical Ingredients production

Autori: Iacoangeli, T.
Pubblicato in: 2024
Editore: Zenodo
DOI: 10.5281/ZENODO.15114540

Other (1)

"Concept paper on ""compliant-by-design"" key-drivers and roadmap of the possible regulatory pathways or relevant regulatory frameworks for the required ""compliant-by-design"" strategies"

Autori: Diego Hernandez Pedraza
Pubblicato in: 2023
Editore: 00000
DOI: 10.5281/ZENODO.12795163