Project description
Chronic diseases are increasing in prevalence, putting pressure on the sustainability of the healthcare systems around the world.
Chronic diseases are increasing in prevalence, putting pressure on the sustainability of the healthcare systems around the world. To address these issues, there has been a growing focus on disease prevention, awareness, and precision medicine. Funded by the HORIZON programme, the NIMSB project will support the establishment of a centre of excellence at the NOVA Institute for Medical Systems Biology (NIMSB) in Lisbon. The aim is to integrate advanced cell analytics, computational approaches, and multi-omics data towards the understanding of chronic diseases and the development of novel therapies. Researchers and clinicians will collaborate to develop quantitative models and implement precision medicine solutions.
Objective
The rise of chronic diseases is shaping health policy priorities worldwide. As the population ages, these conditions affect increasing portions of society and are more difficult to manage, causing suffering in patients and their families for many years. Such increasing prevalence is a threat to the sustainability of healthcare systems. Thus, an increasing focus has been put on disease prevention and awareness, as well as on precision medicine. The Teaming project will create a new Centre of Excellence, NOVA Institute for Medical Systems Biology (NIMSB), which will use the most advanced cell analytics and experimental in vitro systems, combined with computational approaches to understand and fight chronic diseases. The core of the project will be the integration of multi-omics data from single cells from patient biopsies and derived organoids, bioinformatics and artificial intelligence, cell and molecular biology, and relevant animal model studies, to develop quantitative models that can inform on mechanisms of disease progression. Researchers and clinicians will collaborate to use this knowledge to implement novel precision medicine solutions, aiming to intercept diseases before symptoms develop, and also by improving diagnosis, disease course prediction and response to treatment. NIMSB will contribute to clinical practice improvement not only with technology but also by training the next generation of researchers and medical doctors in precision interceptive medicine and digital-transformation technologies. The Max Delbrück Center for Molecular Medicine is the best possible advanced partner, as it is a world leader in this research topic and has recently created the Berlin Institute for Medical Systems Biology, which is a model for NIMSB. Champalimaud Foundation (FC) (PIC 967498371, VAT: 507131827) is included as a third-party entity providing in-kind contributions, in accordance with Article 9.2 of the Horizon Europe Model Grant Agreement. The FC costs will be reported with no profit margin, under internal rates applied to FC researchers, and will be supported by complementary (non-HEU) funding sources.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences artificial intelligence
- medical and health sciences health sciences personalized medicine
- natural sciences biological sciences molecular biology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.4.1 - Widening participation and spreading excellence
MAIN PROGRAMME
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HORIZON.4.1.1 - Teaming
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-CSA - HORIZON Coordination and Support Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-WIDERA-2022-ACCESS-01-two-stage
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2770-186 PACO DE ARCOS
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.