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NOVA Institute for Medical Systems Biology

Projektbeschreibung

DEENESFRITPL

Präzisionsmedizin in Portugal voranbringen

Chronische Erkrankungen treten immer häufiger auf und setzen die Nachhaltigkeit der Gesundheitssysteme weltweit unter Druck. Um diese Problematik zu beheben, wurde der Schwerpunkt zunehmend auf Krankheitsprävention, Sensibilisierung und Präzisionsmedizin gelegt. Das vom HORIZONT-Programm finanzierte Projekt NIMSB wird die Einrichtung eines Exzellenzzentrums am NOVA-Institut für medizinische Systembiologie (NIMSB) in Lissabon unterstützen. Ziel ist es, fortgeschrittene Zellanalysen, rechnergestützte Ansätze und Multi-Omik-Daten zu integrieren, um chronische Erkrankungen zu verstehen und neue Therapien zu entwickeln. Forschende und klinische Fachleute werden zusammenarbeiten, um quantitative Modelle zu erstellen und Lösungen für die Präzisionsmedizin umzusetzen.

Ziel

The rise of chronic diseases is shaping health policy priorities worldwide. As the population ages, these conditions affect increasing portions of society and are more difficult to manage, causing suffering in patients and their families for many years. Such increasing prevalence is a threat to the sustainability of healthcare systems. Thus, an increasing focus has been put on disease prevention and awareness, as well as on precision medicine. This project will create a new Centre of Excellence, NOVA Institute for Medical Systems Biology (NIMSB), which will use the most advanced cell analytics and experimental in vitro systems, combined with computational approaches to understand and fight chronic diseases. The core of the project will be the integration of multi-omics data from single cells from patient biopsies and derived organoids, bioinformatics and artificial intelligence, cell and molecular biology, and relevant animal model studies, to develop quantitative models that can inform on mechanisms of disease progression. Researchers and clinicians will collaborate to use this knowledge to implement novel precision medicine solutions, aiming to intercept diseases before symptoms develop, and also by improving diagnosis, disease course prediction and response to treatment. NIMSB will contribute to clinical practice improvement not only with technology but also by training the next generation of researchers and medical doctors in precision interceptive medicine and digital-transformation technologies. NOVA Medical School of NOVA University is in a unique position to coordinate the project due to its current drive for restructuring, established reputation as a top Medical School in Portugal, and research focus on chronic diseases. The Max Delbrück Center for Molecular Medicine is the best possible advanced partner, as it is a world leader in this research topic and has recently created the Berlin Institute for Medical Systems Biology, which is a model for NIMSB.

Wissenschaftliches Gebiet

Schlüsselbegriffe

Programm/Programme

Thema/Themen

Aufforderung zur Vorschlagseinreichung

HORIZON-WIDERA-2022-ACCESS-01-two-stage

Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

HORIZON-CSA - HORIZON Coordination and Support Actions

Koordinator

UNIVERSIDADE NOVA DE LISBOA
Netto-EU-Beitrag
€ 12 006 000,00
Adresse
CAMPUS DE CAMPOLIDE
1099 085 Lisboa
Portugal

Auf der Karte ansehen
Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 12 006 000,00

Beteiligte (1)

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Letzte Aktualisierung: 28 Juni 2023

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Permalink: https://cordis.europa.eu/project/id/101060346/de

European Union, 2024