Integrating bio-inspired assembly into semiconductor manufacturing technology for biosensors

Informazioni relative al progetto

BIOASSEMBLER

ID dell’accordo di sovvenzione: 101070589

DOI

10.3030/101070589

Progetto chiuso

Data della firma CE 23 Giugno 2022

Data di avvio 1 Settembre 2022

Data di completamento 28 Febbraio 2026

Finanziato da

• Digital, Industry and Space

Costo totale

€ 3 265 740,25

Contributo UE

€ 3 265 740,25

Coordinato da

TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
Finland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (3)

Optimized zipcode sequences

Optimized zipcode sequences.Set of 10 zipcode sequences, including chemical optimization with alternative nucleic acids, optimized for stability, specificity and minimal length.Testing of min 20 and max 100 candidate oligo pairs.Crossreactivity goal <1%.Aiming for sequence length ≤ 12nt.

BIOASSEMBLER DEC plan

BIOASSEMBLER DEC plan: The plan will be submitted to the EU Commission in month 6 after approval by all partners. The report will be public to increase transparency about the communication and dissemination actions to be implemented by the project

Project Quality Management Plan

Project Quality Management Plan PQMP: Internal procedures for communication, progress monitoring, quality assurance and risk management.

Demonstrators, pilots, prototypes (1)

Chemistry for DNA on wafers

Chemistry for DNA on wafers.Functionalization and synthesis protocols for direct photolithographic DNA synthesis on microchips on wafers/wafer sections.Achieving cycle times ≤ 2 min/base.

Other (1)

Ethics Plan

Pubblicazioni

Peer reviewed articles (2)

Dipodal Silanes Greatly Stabilize Glass Surface Functionalization for DNA Microarray Synthesis and High-Throughput Biological Assays

Autori: Arya Das, Santra Santhosh, Maya Giridhar, Jürgen Behr, Timm Michel, Erika Schaudy, Gisela Ibáñez-Redín, Jory Lietard, Mark M Somoza
Pubblicato in: Analytical Chemistry, ISSN 1520-6882
Editore: American Chemical Society
DOI: 10.1021/ACS.ANALCHEM.3C03399

Nonaqueous Oxidation in DNA Microarray Synthesis Improves the Oligonucleotide Quality and Preserves Surface Integrity on Gold and Indium Tin Oxide Substrates

Autori: Erika Schaudy, Gisela Ibañez-Redín, Etkin Parlar, Mark M Somoza, Jory Lietard
Pubblicato in: Analytical Chemistry, ISSN 1520-6882
Editore: Americal Chemical Society
DOI: 10.1021/ACS.ANALCHEM.3C04166

Other (1)

An open-source advanced maskless synthesizer for light-directed chemical synthesis of large nucleic acid libraries and microarrays

Autori: Jürgen Behr, Timm Michel, Maya Giridhar, Santra Santhosh, Arya Das, Hamed Sabzalipoor, Tadija Kekić, Etkin Parlar, Igor Ilić, Gisela Ibáñez-Redín, Erika Schaudy, Jory Lietard, Thomas Schletterer, Max Funck, Mark Somoza
Pubblicato in: ChemRxiv, 2024
Editore: ChemRxiv
DOI: 10.26434/chemrxiv-2024-j4c90