Enlisting synthetic fungal-bacterial consortia to produce multi-cellular mycelium-based ELMs with computational capability

Risultati finali

Portfolio’s Dissemination and communication activities RP1

The report includes a description of the activities, the outcomes and any planned follow up.

Contribution to the regulatory debate in RP1.

Report on the activities, outcomes and planned follow up to assess and address the ELMs portfolio needs. This includes contribution to the regulatory debate by engaging early on and continuously with regulatory bodies. Any confidential information related to these activities will be included in the technical report.

ELSA activities in RP1.

Report on the activities, outcomes and planned follow up to address ethical, legal and social aspects (ELSA). These activities include engagement with strategic partners (including the public), and dissemination of best practices and guidelines when applicable with the ELMs field. Any confidential information related to these activities will be included in the technical report.

A dictionary of the patterns of endogenous spiking of proteinoid ensembles

Report on the design and manufacturing of the experimental setup for recording electrical activity of living composites in a controlled environment, and, from the results, develop a dictionary of the patterns of endogenous spiking of proteinoid ensembles.

ELSA activities in RP2

Report on the activities, outcomes and planned follow up to address ethical, legal and social aspects (ELSA). These activities include engagement with strategic partners (including the public), and dissemination of best practices and guidelines when applicable with the ELMs field. Any confidential information related to these activities will be included in the technical report.

Website and project logo

The project website will be operational by M2 and continuously updated thereafter across the duration of the project. The domain www.fungateria.eu will be procured.The project website will be a first port of call for external access to information relating to the project. The website will be a gateway to multimedia presentations, open software, hardware, research papers and SoMe channels and contains the social media links.

Mapping emerging ethical, social and environmental issues for EML technologies

Report on the mapping of emerging ethical, social and environmental issues for EML technologies with special attention to identified issues of concern that are overlappingwith SDGs such as “sustainable cities and communities” and “responsible and consumption and production”.

Contribution to the regulatory debate in RP2

Report on the activities, outcomes and planned follow up to assess and address the ELMs portfolio needs. This includes contribution to the regulatory debate by engaging early on and continuously with regulatory bodies. Any confidential information related to these activities will be included in the technical report.

A catalog of mapping between ELM topologies and patterns of their electrical activity

Report on models of spiking activity based on concepts of calcium waves, salt-water oscillators and ionic condensation.

Portfolio’s Dissemination and communication activities RP2

The report includes a description of the activities, the outcomes and any planned follow up.

Design and hardware implementation of initial digital twin prototype (DTP)

This deliverable reports on the design and hardware implementation of an initial Digital Twin Prototype (DTP) using and an accumulation of modelling methods (i.e., finite element methods, cellular automata, various neural networks) to mimic the production of ELMs and, most important, their electrical behavior.

Community portal

Community portal is established and populated with preliminary resources. The aim of the portal is to provide a broader insight into ELM development, beyond the focus of the Fungateria project.

Portfolio of ELM designs as digital models

Portfolio of digital designs for ELM morphologies informed by data on qualitative andquantitative parameters such as anticipated biomass generation, distribution and type of functionalities, computational capabilities and morphological development.

Pubblicazioni

Functions of the cell wall polysaccharide schizophyllan during vegetative growth of Schizophyllum commune

Autori: Fleur E. L. Kleijburg, Ella M. Schunselaar, Adil A. Safeer, Marc Baldus & Han A. B. Wösten
Pubblicato in: The Cell Surface, ISSN 2468-2330
Editore: Elsevier
DOI: 10.1016/j.tcsw.2025.100167

Multiscalar electrical spiking in Schizophyllum commune

Autori: Andrew Adamatzky, Ella Schunselaar, Han A. B. Wösten & Phil Ayres
Pubblicato in: Scientific Reports, Numero 13, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1101/2023.04.20.537646v2

Recent technological innovations in mycelium materials as leather substitutes: a patent review

Autori: Elise Elsacker, Simon Vandelook and Eveline Peeters
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 11, 2023, ISSN 2296-4185
Editore: Frontiers
DOI: 10.3389/fbioe.2023.1204861

Micro-electrode array recording of extracellular electrical potentials of liquid static surface fermented Hericium erinaceus

Autori: Davin Browner, Andrew Adamatzky
Pubblicato in: BioSystems, Numero 245, 2024, ISSN 0303-2647
Editore: Elsevier BV
DOI: 10.1016/J.BIOSYSTEMS.2024.105298

Fungi as functors: A category-theoretic approach to mycelial organisation

Autori: Andrew Adamatzky
Pubblicato in: Results in Applied Mathematics, Numero 30, 2026, ISSN 2590-0374
Editore: Elsevier BV
DOI: 10.1016/J.RINAM.2026.100715

Growing sustainable materials from filamentous fungi

Autori: Eveline Peeters, Jara Saluena Martin, Simon Vandelook
Pubblicato in: The Biochemist, Numero 45(3), 2023, ISSN 1740-1194
Editore: Portland Press
DOI: 10.1042/bio_2023_120

Voltage Spiking Synchronicity with Growth Transitions in <i>Trichoderma reesei</i>

Autori: Panagiotis Mougkogiannis, Andrew Adamatzky
Pubblicato in: ACS Applied Bio Materials, Numero 9, 2026, ISSN 2576-6422
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSABM.6C01286

BioSystems

Autori: Tommy Wood, Tuomas Sorakivi, Phil Ayres, Andrew Adamatzky
Pubblicato in: BioSystems, Numero 243, 2024, ISSN 0303-2647
Editore: Elsevier
DOI: 10.1016/J.BIOSYSTEMS.2024.105278

Interactions between fungi, algae, and bacteria: multispecies engineered living materials leverage function and structure

Autori: Marc Kessels Solé, Hannelore Wilssens, Elise Elsacker, Lien De Wannemaeker, Marjan De Mey
Pubblicato in: Current Opinion in Microbiology, Numero 93, 2026, ISSN 1369-5274
Editore: Elsevier BV
DOI: 10.1016/J.MIB.2026.102806

Strength in diversity: unlocking the full potential of engineered living materials with multistrain collaboration

Autori: Hannelore Wilssens, Lien De Wannemaeker, Marjan De Mey
Pubblicato in: FEMS Microbiology Reviews, Numero 49, 2025, ISSN 1574-6976
Editore: Oxford University Press (OUP)
DOI: 10.1093/FEMSRE/FUAF055

Modelling of morphogenesis to support the design of fungal-based engineered living materials

Autori: Vilhelm Carlström, Adrien Rigobello, Phil Ayres
Pubblicato in: Research Directions: Biotechnology Design, Numero 2, 2024, ISSN 2752-9452
Editore: Cambridge University Press (CUP)
DOI: 10.1017/BTD.2024.10

Fungi as Turing automata with oracles

Autori: Andrew Schumann, Andrew Adamatzky, Jerzy Król, Eric Goles
Pubblicato in: Royal Society Open Science, Numero 11, 2024, ISSN 2054-5703
Editore: The Royal Society
DOI: 10.1098/RSOS.240768

Fungal biohybrid substrates for resilient sensing and embodied anomaly detection

Autori: Andrew Adamatzky
Pubblicato in: BioSystems, Numero 262, 2026, ISSN 0303-2647
Editore: Elsevier BV
DOI: 10.1016/J.BIOSYSTEMS.2026.105739

Propagation of electrical spike trains in substrates colonised by oyster fungi

Autori: Andrew Adamatzky
Pubblicato in: Scientific Reports, Numero 16, 2026, ISSN 2045-2322
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41598-026-47035-2

Scanning electron microscopy of hyphal ectobiont bacteria within mycelial extracellular matrices

Autori: Davin Browner, Andrew Adamatzky
Pubblicato in: Biophysical Reports, Numero 5, 2025, ISSN 2667-0747
Editore: Elsevier BV
DOI: 10.1016/J.BPR.2025.100233

Tuning electrical spiking of Schizophyllum commune with light

Autori: Davin Browner, Andrew Adamatzky, Ella Schunselaar, Han A. B. Wösten, Phil Ayres
Pubblicato in: 2023
Editore: Preprint
DOI: 10.1101/2023.09.26.559269

Risultati dei progetti

Risultati finali

Pubblicazioni

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