Doctoral network for microprocess engineering for electrosynthesis - new synthesis concepts for pharmaceutical/ fine chemical industry

Informazioni relative al progetto

MiEL

ID dell’accordo di sovvenzione: 101073003

DOI

10.3030/101073003

Data della firma CE 28 Novembre 2022

Data di avvio 1 Gennaio 2023

Data di completamento 30 Giugno 2027

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 2 511 762,20

Coordinato da

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (2)

10 relevant publications by mid-term

see title

Project website

Project website (M2)

Documents, reports (1)

Method/process for the fluorination/trifluoromethylation of organic molecules

see title

Other (1)

Continuum-scale flow cell model published including open-source code

See title

Pubblicazioni

Peer reviewed articles (11)

Flow Electroreductive Nickel‐Catalyzed Cyclopropanation of Alkenes Using <i>gem</i>‐Dichloroalkanes

Autori: Morgan Regnier, Clara Vega, Dimitris I. Ioannou, Zhenyu Zhang, Timothy Noël
Pubblicato in: Angewandte Chemie International Edition, 2025, ISSN 1433-7851
Editore: Wiley
DOI: 10.1002/ANIE.202500203

Electrosynthesis of Aryliminophosphoranes in Continuous Flow

Autori: Rodrigo Costa e Silva, Clara Vega, Morgan Regnier, Luca Capaldo, Lars Wesenberg, Grace Lowe, Kleber Thiago de Oliveira, Timothy Nol
Pubblicato in: Advanced Synthesis &amp; Catalysis, Numero 366, 2023, ISSN 1615-4150
Editore: Wiley
DOI: 10.1002/adsc.202300635

Enhancing electrochemical reactions in organic synthesis: the impact of flow chemistry

Autori: Morgan Regnier, Clara Vega, Dimitris I. Ioannou, Timothy Nol
Pubblicato in: Chemical Society Reviews, Numero 53, 2024, ISSN 0306-0012
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/d4cs00539b

Deracemization by coupling electrochemically assisted racemization and asymmetric crystallization

Autori: Anne-Sophie Léonard, Morgan Regnier, Susanna Bertuletti, Sjoerd W. van Dongen, Roberta Listro, Michel Leeman, Richard M. Kellogg, Timothy Noël, Willem L. Noorduin
Pubblicato in: Chemical Communications, Numero 61, 2025, ISSN 1359-7345
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5CC05874K

Local Variations in Current Density and Selectivity in CO ₂ Electrolyzers

Autori: Pedro Arias Villaroel, Egon Kecsenovity, Csaba Janáky
Pubblicato in: ACS Energy Letters, Numero 11, 2026, ISSN 2380-8195
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSENERGYLETT.5C03770

Electrochemical CO and CN Arylation using Alternating Polarity in flow for Compound Libraries

Autori: Jennifer Morvan, Koen P. L. Kuijpers, Dayne Fanfair, Bingqing Tang, Karolina Bartkowiak, Lars van Eynde, Evelien Renders, Jesus Alcazar, Peter J. J. A. Buijnsters, MaryAmbre Carvalho, Alexander X. Jones
Pubblicato in: Angewandte Chemie International Edition, Numero 64, 2024, ISSN 1433-7851
Editore: Wiley
DOI: 10.1002/anie.202413383

Simulation-based techno-economic optimization of continuous ibuprofen manufacturing under uncertainty

Autori: T. Asrav, M. Alvarado-Morales, G. Sin
Pubblicato in: Chemical Engineering Research and Design, Numero 231, 2026, ISSN 0263-8762
Editore: Elsevier BV
DOI: 10.1016/J.CHERD.2026.06.051

Rapid Methylation of Aryl Bromides Using Air-Stable DABCO-Bis(Trimethylaluminum) via Nickel Metallaphotoredox Catalysis

Autori: Djossou, J.; Capaldo, L.; Snabilie, D.; Regnier, M.; Monopoli, A.; de Bruin, B.; and Noël, T
Pubblicato in: Angew. Chem. Int. Ed., 2025
Editore: Wiley
DOI: 10.1002/ANIE.202508710

Local Variations in Current Density and Selectivity in CO ₂ Electrolyzers

Autori: Pedro Arias Villaroel, Egon Kecsenovity, Csaba Janáky
Pubblicato in: ACS Energy Letters, 2026, ISSN 2380-8195
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSENERGYLETT.5C03770

Autonomous optimization of continuous-flow diazo intermediates synthesis

Autori: Gonzalo Araya Vargas, Maud Schwarzer, Alexander Mendl, Dusan Boskovic
Pubblicato in: Reaction Chemistry &amp; Engineering, 2026, ISSN 2058-9883
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/D6RE00154H

Enabling electrochemical, decarboxylative C(sp2)–C(sp3) cross-coupling for parallel medicinal chemistry

Autori: Jennifer Morvan, Bingqing Tang, Pavel Ryabchuk, Evelien Renders, Stefaan Last, Lars Van Eynde, Karolina Bartkowiak, Peter J.J.A. Buijnsters, Alexander X. Jones, Mary-Ambre Carvalho, Justin B. Diccianni
Pubblicato in: European Journal of Medicinal Chemistry, Numero 291, 2025, ISSN 0223-5234
Editore: Elsevier BV
DOI: 10.1016/J.EJMECH.2025.117583

Conference proceedings (7)

Measurement of Temperature in Parallel Channel of Microfluidic Reactors

Autori: Abdullah Khan, Morgan Regnier, Duan Kopecky
Pubblicato in: 2024 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS), 2024
Editore: IEEE
DOI: 10.1109/FLEPS61194.2024.10603875

W7.3.3 - PCB-Based Electrochemical Electrodes with Self-temperature Regulation Functionality for Electrochemical Studies at Target Temperatures

Autori: M. Derakhshani, T. Posnicek, M. Brandl, W. Hilber, S. Mirsian, B. Jakoby
Pubblicato in: Lectures, 2025
Editore: AMA Service GmbH, Von-Münchhausen-Str. 49, 31515 Wunstorf
DOI: 10.5162/EUROSENSORS2025/W7.3.3

Through-Wall Temperature Sensing in Flow Reactors Using PCB-Integrated Thermistors

Autori: Abdullah Khan, Dusan Kopecky
Pubblicato in: 2026 IEEE 23rd International Multi-Conference on Systems, Signals &amp;amp; Devices (SSD), 2026
Editore: IEEE
DOI: 10.1109/SSD69655.2026.11558985

Development of a ML-Driven Self-Optimization workflow for the production of Nitrogen-rich compounds in continuous processing

Autori: Gonzalo Araya Vargas, Dusan Boskovic, Maud Schwarzer, Alexander Mendl
Pubblicato in: "Artificial Intelligence, Machine Learning and Data Science in Energetic Materials Research, 54th International Annual Conference of Fraunhofer ICT""", 2025
Editore: Fraunhofer ICT
DOI: 10.5281/ZENODO.17098099

Mapping of Local Selectivity and Current Density in Zero-Gap CO2 Electrolysers

Autori: Pedro Arias Villarroel, Egon Kecsenovity, Csaba Janaky
Pubblicato in: ECS 248th, 2025
Editore: ECS

Decarbonizing API Manufacturing: Conceptual Design and Scale-up Analysis of Continuous-Flow Electrosynthesis for Ibuprofen Production

Autori: Tuse Asrav, Merlin Alvarado-Morales, Gürkan Sin
Pubblicato in: Systems and Control Transactions, Proceedings of the 36th European Symposium on Computer Aided Process Engineering (ESCAPE 36), Numero 6, 2026
Editore: PSE Press
DOI: 10.69997/SCT.137213

Conceptual Modular Design for Continuous Pharmaceutical Processes: A Case Study on Ibuprofen

Autori: T. Asrav, M. Alvarado-Morales, G. Sin
Pubblicato in: 2025, ISBN 978-9-492859-36-5
Editore: EUROSIS

Other (1)

Method/process for the fluorination/trifluoromethylation of organic molecules

Autori: Dr. Julia Melke
Pubblicato in: 2024
Editore: MIEI