Preventing lifetime obesity by early risk-factor identification, prognosis and intervention

Información del proyecto

eprObes

Identificador del acuerdo de subvención: 101080219

DOI

10.3030/101080219

Fecha de la firma de la CE 11 Abril 2023

Fecha de inicio 1 Mayo 2023

Fecha de finalización 30 Abril 2028

Financiado con arreglo a

• Health

Coste total

€ 9 875 071,25

Aportación de la UE

€ 9 875 071,25

Coordinado por

CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P.
Spain

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (1)

D/C/E Plan of eprObes

Generation of Dissemination, Communication & Exploita-tion (D/C/E) Plan for eprObes

Websites, patent fillings, videos etc. (2)

Project website & Observatory

Development of eprObes website, incl. a repository of all the result (Observatory)

Project Handbook

Development of eprObes handbook

Publicaciones

Peer reviewed articles (27)

Multiomics and eXplainable artificial intelligence for decision support in insulin resistance early diagnosis: A pediatric population-based longitudinal study

Autores: Álvaro Torres-Martos, Augusto Anguita-Ruiz, Mireia Bustos-Aibar, Alberto Ramírez-Mena, María Arteaga, Gloria Bueno, Rosaura Leis, Concepción M. Aguilera, Rafael Alcalá, Jesús Alcalá-Fdez
Publicado en: Artificial Intelligence in Medicine, Edición 156, 2024, ISSN 0933-3657
Editor: Elsevier BV
DOI: 10.1016/j.artmed.2024.102962

Probiotic and prebiotic interventions in eating disorders: A narrative review

Autores: Isabel Baenas, Lucía Camacho‐Barcia, Romina Miranda‐Olivos, Neus Solé‐Morata, Alejandra Misiolek, Susana Jiménez‐Murcia, Fernando Fernández‐Aranda
Publicado en: European Eating Disorders Review, Edición 32, 2024, ISSN 1072-4133
Editor: Wiley
DOI: 10.1002/erv.3069

The evolutionary conserved miR-137/325 tandem mediates obesity-induced hypogonadism and metabolic comorbidities by repressing hypothalamic kisspeptin

Autores: María S. Avendaño, Cecilia Perdices-Lopez, Yolanda Guerrero-Ruiz, Francisco Ruiz-Pino, Ana B. Rodriguez-Sanchez, María J. Sanchez-Tapia, Verónica Sobrino, Rafael Pineda, Alexia Barroso, Alejandro Correa-Sáez, Maribel Lara-Chica, José C. Fernandez-Garcia, Ana B. García-Redondo, Raquel Hernanz, Miguel Ruiz-Cruz, David Garcia-Galiano, Nelly Pitteloud, Marco A. Calzado, Ana M. Briones, María J. Vázquez, Manuel Tena-Sempere
Publicado en: Metabolism, Edición 157, 2024, ISSN 0026-0495
Editor: Elsevier BV
DOI: 10.1016/j.metabol.2024.155932

Kisspeptins centrally modulate food intake and locomotor activity in mice independently of gonadal steroids in a sexually dimorphic manner

Autores: Inmaculada Velasco; Silvia DazaDueas; Encarnacin Torres; Francisco RuizPino; Mara J. Vzquez; Manuel TenaSempere
Publicado en: Journal of Neuroendocrinology, 2024, ISSN 1365-2826
Editor: Wiley
DOI: 10.1111/jne.13433

<scp>STING</scp> inhibition alleviates experimental peritoneal damage: potential therapeutic relevance for peritoneal dialysis

Autores: Vanessa Marchant, Jorge García‐Giménez, Guadalupe T González‐Mateo, Pilar Sandoval, Lucía Tejedor‐Santamaria, Sandra Rayego‐Mateos, Ricardo Ramos, José A Jiménez‐Heffernan, Alberto Ortiz, Anne‐Catherine Raby, Manuel López‐Cabrera, Adrián M Ramos, Marta Ruiz‐Ortega
Publicado en: The Journal of Pathology, Edición 267, 2025, ISSN 0022-3417
Editor: Wiley
DOI: 10.1002/PATH.6462

Serum DLK1 During Minipuberty and Pubertal Transition in Healthy Girls and in Girls With Precocious Puberty

Autores: Lea Vilmann, Kaspar Sørensen, Alexander S Busch, Marie L Ljubicic, Emmie N Upners, Margit B Fischer, Trine H Johannsen, Stine A Holmboe, Anders Juul, Casper P Hagen
Publicado en: The Journal of Clinical Endocrinology &amp; Metabolism, 2024, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgae762

Determinants of Parents' and Adolescents' Motivation Before Pediatric Weight Management—Data From the <scp>STARKIDS</scp> Cohort

Autores: Anne Herschbach, Rebecca Erschens, Florian Junne, Stefan Ehehalt, Johann Jacoby, Peter Martus, Isabelle Mack, Alisa Weiland, Inga Krauß, Constanze Greule, Guido Zurstiege, Annalena Wels, Sophia Helen Adam, Andreas Hoell, Wolfgang Bethge, Monika Ums, Torben Sammet, Maren Reyer, Olaf Schliesing, Stephan Zipfel, Caterina Gawrilow, Katrin Elisabeth Giel, Katrin Ziser
Publicado en: Obesity, 2026, ISSN 1930-7381
Editor: Wiley
DOI: 10.1002/OBY.70185

Longitudinal dynamics of impulsivity in individuals undergoing obesity surgery – a systematic review

Autores: Katrin Elisabeth Giel, Lucia Camacho-Barcia, Laura Schultze-Rhonhof, Fernando Fernandez-Aranda, Stephan Zipfel, Kathrin Schag
Publicado en: Reviews in Endocrine and Metabolic Disorders, 2025, ISSN 1389-9155
Editor: Springer Science and Business Media LLC
DOI: 10.1007/S11154-025-10000-X

Predictors of Body Weight Loss and Body Weight Loss Maintenance in Children and Adolescents following Inpatient Multidisciplinary Obesity Treatment

Autores: Weiland, Alisa; Kasemann, Lena; Sauer, Helene; Horing, Björn; Zipfel, Stephan; Mazurak, Nazar; Enck, Paul; Mack, Isabelle
Publicado en: Obesity Facts, ISSN 1662-4033
Editor: S. Karger AG
DOI: 10.1159/000548602

Cluster analysis in gambling disorder based on sociodemographic, neuropsychological, and neuroendocrine features regulating energy homeostasis

Autores: Baenas, Isabel; Mora Maltas, Bernat; Etxandi, Mikel; Lucas, Ignacio; Granero, Roser; Fernndez Aranda, Fernando; Tovar, Sulay; Sol Morata, Neus; Gmez Pea, Mnica; Moragas, Laura; Del Pino Gutirrez, Amparo; Tapia, Javier; Diguez, Carlos; Goudriaan, Anna E.; Jimnez-Murcia, Susana
Publicado en: Comprehensive Psychiatry, 2024, ISSN 0000-0000
Editor: DOAJ
DOI: 10.1016/j.comppsych.2023.152435

Beyond M1/M2: The role of reactive oxygen species in liver fibrosis and immune modulation

Autores: Huilun Lu, Jie Huang, Ya-chao Wang, Eudald Casals, Gregori Casals, Muling Zeng
Publicado en: Redox Biology, Edición 88, 2026, ISSN 2213-2317
Editor: Elsevier BV
DOI: 10.1016/J.REDOX.2025.103933

Rethinking cutoff values for the South Oaks Gambling Screen: Sex-specific insights and DSM-5 severity adjustments in Gambling Disorder assessment

Autores: Ignacio Lucas, Roser Granero, Bernat Mora-Maltas, Fernando Fernández-Aranda, Susana Jiménez-Murcia
Publicado en: Journal of Behavioral Addictions, Edición 13, 2024, ISSN 2062-5871
Editor: Akademiai Kiado Zrt.
DOI: 10.1556/2006.2024.00053

Troxerutin is a novel osmotic agent for peritoneal dialysis with protective cardiovascular actions

Autores: Valeria Kopytina, Vanessa Marchant, Raquel Rodrigues-Diez, Lucía Pascual-Antón, Nora Toggweiler, Lisa Strahl, Jamie Kane, Antonio Tejera-Muñoz, Marcelino Cortés, David Sucunza, Juan J Vaquero, Marc Vervloet, Dorothea Piecha, Etto C Eringa, Marta Ruiz-Ortega, Manuel López-Cabrera, Guadalupe T González-Mateo
Publicado en: Nephrology Dialysis Transplantation, 2025, ISSN 0931-0509
Editor: Oxford University Press (OUP)
DOI: 10.1093/NDT/GFAF249

Biofeedback Interventions for Impulsivity-related Processes in Addictive Disorders

Autores: Ignacio Lucas; Neus Sol-Morata; Isabel Baenas; Magda Rosinska; Fernando Fernndez-Aranda; Susana Jimnez-Murcia
Publicado en: Current Addiction Reports, 2023, ISSN 2196-2952
Editor: Springer Nature
DOI: 10.1007/s40429-023-00499-y

Nutrients

Autores: Lucía Camacho-Barcia; Isabel Sánchez; Ana Ibáñez-Caparrós; Noriaki Ohsako; Roser Granero; Cristina Artero; José Manuel Crespo; Georgios Paslakis; Susana Jiménez-Murcia; Fernando Fernández-Aranda
Publicado en: Nutrients, 2024, ISSN 2072-6643
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/NU16142337

Association between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population

Autores: I. Baenas; L. Camacho-Barcia; R. Granero; C. Razquin; D. Corella; C. Gmez-Martnez; O. Castaer-Nio; J. A. Martnez; . M. Alonso-Gmez; J. Wrnberg; J. Vioque; D. Romaguera; J. Lpez-Miranda; R. Estruch; F. J. Tinahones; J. Lapetra; J. L. Serra-Majem; N. Cano-Ibez; J. A. Tur; V. Martn-Snchez; X. Pint; J. J. Gaforio; P. Mata-Martn; J. Vidal; C. Vzquez; L. Daimiel; E. Ros; S. Jimnez-Murcia; S. Dalsgaard; A. Garcia-Arellano; N. Babio; J. V. Sorli; C. Lassale; M. Garca-de-la-Hera; E. Gmez-Garca; M. A. Zulet; J. Konieczna; S. Martn-Pelez; L. Tojal-Sierra; F. J. Basterra-Gortari; S. de las Heras-Delgado; O. Portoles; M. . Muoz-Prez; A. P. Arenas-Larriva; L. Compa-Gabucio; S. Eguaras; S. Shyam; M. Fit; R. M. Baos; J. Salas-Salvad; F. Fernndez-Aranda
Publicado en: Journal of Endocrinological Investigation, 2024, ISSN 0000-0000
Editor: Scopus 20
DOI: 10.1007/s40618-023-02278-y

Eating disorders and obesity: bridging clinical, neurobiological, and therapeutic perspectives

Autores: Lucia Camacho-Barcia, Katrin Elisabeth Giel, Susana Jiménez-Murcia, Julio Álvarez Pitti, Nadia Micali, Ignacio Lucas, Romina Miranda-Olivos, Lucero Munguia, Manuel Tena-Sempere, Stephan Zipfel, Fernando Fernández-Aranda
Publicado en: Trends in Molecular Medicine, Edición 30, 2024, ISSN 1471-4914
Editor: Elsevier BV
DOI: 10.1016/j.molmed.2024.02.007

Higher peak height velocity in early maturing girls depends on insulin rather than fat mass or IGF-I

Autores: Kaspar Sørensen, Casper P Hagen, Anders Juul
Publicado en: European Journal of Endocrinology, Edición 191, 2024, ISSN 0804-4643
Editor: Oxford University Press (OUP)
DOI: 10.1093/EJENDO/LVAE115

The role of motivation in weight reduction programs for children and adolescents with overweight or obesity: a systematic review

Autores: Herschbach, Anne; Wels, Annalena; Dieckmann, Pauline; Erschens, Rebecca; Junne, Florian; Ehehalt, Stefan; Zipfel, Stephan; Giel, Katrin Elisabeth; Ziser, Katrin
Publicado en: Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 2025, ISSN 1590-1262
Editor: Springer Nature
DOI: 10.1007/S40519-025-01763-Y

Association of anandamide and 2-arachidonoylglycerol concentrations with clinical features and body mass index in eating disorders and obesity

Autores: Isabel Baenas; Romina Miranda-Olivos; Roser Granero; Neus Sol-Morata; Isabel Snchez; Antoni Pastor; Amparo del Pino-Gutirrez; Ester Codina; Francisco J. Tinahones; Jos A. Fernndez-Formoso; Nria Vilarrasa; Fernando Guerrero-Prez; Rafael Lopez-Urdiales; Nria Virgili; Carles Soriano-Mas; Susana Jimnez-Murcia; Rafael de la Torre; Fernando Fernndez-Aranda
Publicado en: European Psychiatry, 2023, ISSN 0000-0000
Editor: Cambridge University Press
DOI: 10.1192/j.eurpsy.2023.2411

Journal of Behavioral Addictions

Autores: Mikel Etxandi; Isabel Baenas; Bernat Mora-Maltas; Roser Granero; Fernando Fernández-Aranda; Sulay Tovar; Neus Solé-Morata; Ignacio Lucas; Sabela Casado; Mónica Gómez-Peña; Laura Moragas; Amparo del Pino-Gutiérrez; Javier Tapia; Eduardo Valenciano-Mendoza; Marc N. Potenza; Ashley N. Gearhardt; Carlos Diéguez; Susana Jiménez-Murcia
Publicado en: Journal of Behavioral Addictions, 2023, ISSN 2062-5871
Editor: Akademiai Kiado
DOI: 10.1556/2006.2023.00051

Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder

Autores: Isabel Baenas; Neus Sol-Morata; Roser Granero; Fernando Fernndez-Aranda; Mitona Pujadas; Bernat Mora-Maltas; Ignacio Lucas; Mnica Gmez-Pea; Laura Moragas; Amparo del Pino-Gutirrez; Javier Tapia; Rafael de la Torre; Marc N. Potenza; Susana Jimnez-Murcia
Publicado en: European Psychiatry, 2023, ISSN 0000-0000
Editor: Cambridge University Press
DOI: 10.1192/j.eurpsy.2023.2460

Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity

Autores: Romina Miranda-Olivos; Isabel Baenas; Trevor Steward; Roser Granero; ANTONI PASTOR; Isabel Snchez; Asier Juaneda; Amparo Del Pino; Jose A. Fernndez-Formoso; Nuria Vilarrasa; Fernando Guerrero-Prez; Nuria Virgili; Rafael Lpez-Urdiales; Susana Jimnez-Murcia; Rafael de la Torre; Carles Soriano-Mas; Fernando Fernandez-Aranda
Publicado en: Molecular Psychiatry, 2023, ISSN 0000-0000
Editor: Dipòsit Digital de la Universitat de Barcelona
DOI: 10.21203/rs.3.rs-3008676/v1

The Effect of Maternal Diet and Lifestyle on the Risk of Childhood Obesity

Autores: Edyta Łuszczki, Justyna Wyszyńska, Agnieszka Dymek, Dorota Drożdż, Laura González-Ramos, Isa Hartgring, Nuria García-Carbonell, Artur Mazur, Serap Erdine, Justė Parnarauskienė, Julio Alvarez-Pitti
Publicado en: Metabolites, Edición 14, 2024, ISSN 2218-1989
Editor: MDPI AG
DOI: 10.3390/metabo14120655

Endocrine nanozymology: Nanozyme applications in diabetes, obesity, and hormonal disorders

Autores: Huilun Lu, Zizhong Liu, Ya-chao Wang, Eudald Casals, Felicia A Hanzu, Manuel Morales-Ruiz, Muling Zeng, Gregori Casals
Publicado en: Theranostics, Edición 16, 2025, ISSN 1838-7640
Editor: Ivyspring International Publisher
DOI: 10.7150/THNO.122577

Biomarker and clinical data–based predictor tool (MAUXI) for ultrafiltration failure and cardiovascular outcome in peritoneal dialysis patients: a retrospective and longitudinal study

Autores: Eva María Arriero-País, María Auxiliadora Bajo-Rubio, Roberto Arrojo-García, Pilar Sandoval, Guadalupe Tirma González-Mateo, Patricia Albar-Vizcaíno, Gloria del Peso-Gilsanz, Marta Ossorio-González, Pedro Majano, Manuel López-Cabrera
Publicado en: BMJ Health &amp; Care Informatics, Edición 32, 2026, ISSN 2632-1009
Editor: BMJ
DOI: 10.1136/BMJHCI-2024-101138

Applying psycho-behavioural phenotyping in obesity characterization

Autores: Luca Camacho-Barcia; Ignacio Lucas; Romina Miranda-Olivos; Susana Jimnez-Murcia; Fernando Fernndez-Aranda
Publicado en: Reviews in Endocrine and Metabolic Disorders, 2023, ISSN 1573-2606
Editor: Springer Nature
DOI: 10.1007/s11154-023-09810-8

Conference proceedings (1)

Leveraging Machine Learning and Genetic Risk Scores for the Prediction of Metabolic Syndrome in Children with Obesity

Autores: Concepcin M. Aguilera; Mireia Bustos-Aibar; Augusto Anguita-Ruiz; lvaro Torres-Martos; Gloria Bueno; Rosaura Leis; Jess Alcal-Fernndez
Publicado en: The 14th European Nutrition Conference FENS 2023, 2024
Editor: MDPI Proceedings
DOI: 10.3390/proceedings2023091377