Preventing lifetime obesity by early risk-factor identification, prognosis and intervention

Informacje na temat projektu

eprObes

Identyfikator umowy o grant: 101080219

DOI

10.3030/101080219

Data podpisania przez KE 11 Kwietnia 2023

Data rozpoczęcia 1 Maja 2023

Data zakończenia 30 Kwietnia 2028

Finansowanie w ramach

• Health

Koszt całkowity

€ 9 875 071,25

Wkład UE

€ 9 875 071,25

Koordynowany przez

CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P.
Spain

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (1)

D/C/E Plan of eprObes

Generation of Dissemination, Communication & Exploita-tion (D/C/E) Plan for eprObes

Websites, patent fillings, videos etc. (2)

Project website & Observatory

Development of eprObes website, incl. a repository of all the result (Observatory)

Project Handbook

Development of eprObes handbook

Publikacje

Peer reviewed articles (37)

Multiomics and eXplainable artificial intelligence for decision support in insulin resistance early diagnosis: A pediatric population-based longitudinal study

Autorzy: Álvaro Torres-Martos, Augusto Anguita-Ruiz, Mireia Bustos-Aibar, Alberto Ramírez-Mena, María Arteaga, Gloria Bueno, Rosaura Leis, Concepción M. Aguilera, Rafael Alcalá, Jesús Alcalá-Fdez
Opublikowane w: Artificial Intelligence in Medicine, Numer 156, 2024, ISSN 0933-3657
Wydawca: Elsevier BV
DOI: 10.1016/j.artmed.2024.102962

Probiotic and prebiotic interventions in eating disorders: A narrative review

Autorzy: Isabel Baenas, Lucía Camacho‐Barcia, Romina Miranda‐Olivos, Neus Solé‐Morata, Alejandra Misiolek, Susana Jiménez‐Murcia, Fernando Fernández‐Aranda
Opublikowane w: European Eating Disorders Review, Numer 32, 2024, ISSN 1072-4133
Wydawca: Wiley
DOI: 10.1002/erv.3069

The evolutionary conserved miR-137/325 tandem mediates obesity-induced hypogonadism and metabolic comorbidities by repressing hypothalamic kisspeptin

Autorzy: María S. Avendaño, Cecilia Perdices-Lopez, Yolanda Guerrero-Ruiz, Francisco Ruiz-Pino, Ana B. Rodriguez-Sanchez, María J. Sanchez-Tapia, Verónica Sobrino, Rafael Pineda, Alexia Barroso, Alejandro Correa-Sáez, Maribel Lara-Chica, José C. Fernandez-Garcia, Ana B. García-Redondo, Raquel Hernanz, Miguel Ruiz-Cruz, David Garcia-Galiano, Nelly Pitteloud, Marco A. Calzado, Ana M. Briones, María J. Vázquez, Manuel Tena-Sempere
Opublikowane w: Metabolism, Numer 157, 2024, ISSN 0026-0495
Wydawca: Elsevier BV
DOI: 10.1016/j.metabol.2024.155932

Kisspeptins centrally modulate food intake and locomotor activity in mice independently of gonadal steroids in a sexually dimorphic manner

Autorzy: Inmaculada Velasco; Silvia DazaDueas; Encarnacin Torres; Francisco RuizPino; Mara J. Vzquez; Manuel TenaSempere
Opublikowane w: Journal of Neuroendocrinology, 2024, ISSN 1365-2826
Wydawca: Wiley
DOI: 10.1111/jne.13433

<scp>STING</scp> inhibition alleviates experimental peritoneal damage: potential therapeutic relevance for peritoneal dialysis

Autorzy: Vanessa Marchant, Jorge García‐Giménez, Guadalupe T González‐Mateo, Pilar Sandoval, Lucía Tejedor‐Santamaria, Sandra Rayego‐Mateos, Ricardo Ramos, José A Jiménez‐Heffernan, Alberto Ortiz, Anne‐Catherine Raby, Manuel López‐Cabrera, Adrián M Ramos, Marta Ruiz‐Ortega
Opublikowane w: The Journal of Pathology, Numer 267, 2025, ISSN 0022-3417
Wydawca: Wiley
DOI: 10.1002/PATH.6462

Serum DLK1 During Minipuberty and Pubertal Transition in Healthy Girls and in Girls With Precocious Puberty

Autorzy: Lea Vilmann, Kaspar Sørensen, Alexander S Busch, Marie L Ljubicic, Emmie N Upners, Margit B Fischer, Trine H Johannsen, Stine A Holmboe, Anders Juul, Casper P Hagen
Opublikowane w: The Journal of Clinical Endocrinology &amp; Metabolism, 2024, ISSN 0021-972X
Wydawca: The Endocrine Society
DOI: 10.1210/clinem/dgae762

Determinants of Parents' and Adolescents' Motivation Before Pediatric Weight Management—Data From the <scp>STARKIDS</scp> Cohort

Autorzy: Anne Herschbach, Rebecca Erschens, Florian Junne, Stefan Ehehalt, Johann Jacoby, Peter Martus, Isabelle Mack, Alisa Weiland, Inga Krauß, Constanze Greule, Guido Zurstiege, Annalena Wels, Sophia Helen Adam, Andreas Hoell, Wolfgang Bethge, Monika Ums, Torben Sammet, Maren Reyer, Olaf Schliesing, Stephan Zipfel, Caterina Gawrilow, Katrin Elisabeth Giel, Katrin Ziser
Opublikowane w: Obesity, 2026, ISSN 1930-7381
Wydawca: Wiley
DOI: 10.1002/OBY.70185

Hypothalamic obesity: from basic mechanisms to clinical perspectives

Autorzy: Jesús Argente, I Sadaf Farooqi, Julie A Chowen, Peter Kühnen, Miguel López, Eugenia Morselli, Hoong-Wei Gan, Helen A Spoudeas, Martin Wabitsch, Manuel Tena-Sempere
Opublikowane w: The Lancet Diabetes &amp; Endocrinology, Numer 13, 2026, ISSN 2213-8587
Wydawca: Elsevier BV
DOI: 10.1016/S2213-8587(24)00283-3

Longitudinal dynamics of impulsivity in individuals undergoing obesity surgery – a systematic review

Autorzy: Katrin Elisabeth Giel, Lucia Camacho-Barcia, Laura Schultze-Rhonhof, Fernando Fernandez-Aranda, Stephan Zipfel, Kathrin Schag
Opublikowane w: Reviews in Endocrine and Metabolic Disorders, 2025, ISSN 1389-9155
Wydawca: Springer Science and Business Media LLC
DOI: 10.1007/S11154-025-10000-X

Predictors of Body Weight Loss and Body Weight Loss Maintenance in Children and Adolescents following Inpatient Multidisciplinary Obesity Treatment

Autorzy: Weiland, Alisa; Kasemann, Lena; Sauer, Helene; Horing, Björn; Zipfel, Stephan; Mazurak, Nazar; Enck, Paul; Mack, Isabelle
Opublikowane w: Obesity Facts, ISSN 1662-4033
Wydawca: S. Karger AG
DOI: 10.1159/000548602

Cluster analysis in gambling disorder based on sociodemographic, neuropsychological, and neuroendocrine features regulating energy homeostasis

Autorzy: Baenas, Isabel; Mora Maltas, Bernat; Etxandi, Mikel; Lucas, Ignacio; Granero, Roser; Fernndez Aranda, Fernando; Tovar, Sulay; Sol Morata, Neus; Gmez Pea, Mnica; Moragas, Laura; Del Pino Gutirrez, Amparo; Tapia, Javier; Diguez, Carlos; Goudriaan, Anna E.; Jimnez-Murcia, Susana
Opublikowane w: Comprehensive Psychiatry, 2024, ISSN 0000-0000
Wydawca: DOAJ
DOI: 10.1016/j.comppsych.2023.152435

Beyond M1/M2: The role of reactive oxygen species in liver fibrosis and immune modulation

Autorzy: Huilun Lu, Jie Huang, Ya-chao Wang, Eudald Casals, Gregori Casals, Muling Zeng
Opublikowane w: Redox Biology, Numer 88, 2026, ISSN 2213-2317
Wydawca: Elsevier BV
DOI: 10.1016/J.REDOX.2025.103933

OBEClust: joining forces to prevent obesity

Autorzy: Manuel Tena-Sempere, Dimitrios-Dionyssios Koutsouris, George Dedoussis, Jeroen Lakerveld, Karl-Heinz Wagner, Itziar Tueros, Philippe Froguel, Torsten Bohn, Paulo J. Oliveira
Opublikowane w: Nature Reviews Endocrinology, Numer 22, 2026, ISSN 1759-5029
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/S41574-025-01212-X

Rethinking cutoff values for the South Oaks Gambling Screen: Sex-specific insights and DSM-5 severity adjustments in Gambling Disorder assessment

Autorzy: Ignacio Lucas, Roser Granero, Bernat Mora-Maltas, Fernando Fernández-Aranda, Susana Jiménez-Murcia
Opublikowane w: Journal of Behavioral Addictions, Numer 13, 2024, ISSN 2062-5871
Wydawca: Akademiai Kiado Zrt.
DOI: 10.1556/2006.2024.00053

Troxerutin is a novel osmotic agent for peritoneal dialysis with protective cardiovascular actions

Autorzy: Valeria Kopytina, Vanessa Marchant, Raquel Rodrigues-Diez, Lucía Pascual-Antón, Nora Toggweiler, Lisa Strahl, Jamie Kane, Antonio Tejera-Muñoz, Marcelino Cortés, David Sucunza, Juan J Vaquero, Marc Vervloet, Dorothea Piecha, Etto C Eringa, Marta Ruiz-Ortega, Manuel López-Cabrera, Guadalupe T González-Mateo
Opublikowane w: Nephrology Dialysis Transplantation, 2025, ISSN 0931-0509
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/NDT/GFAF249

Biofeedback Interventions for Impulsivity-related Processes in Addictive Disorders

Autorzy: Ignacio Lucas; Neus Sol-Morata; Isabel Baenas; Magda Rosinska; Fernando Fernndez-Aranda; Susana Jimnez-Murcia
Opublikowane w: Current Addiction Reports, 2023, ISSN 2196-2952
Wydawca: Springer Nature
DOI: 10.1007/s40429-023-00499-y

International Journal of Molecular Sciences

Autorzy: Jose Bellver; Marta Gonzalez-Monfort; Sandra González; Bruno Toson; Elena Labarta; Gemma Castillón; Giulia Mariani; Carmina Vidal; Juan Giles; Fabio Cruz; Agustin Ballesteros; Marcos Ferrando; Juan Antonio García-Velasco; Diana Valbuena; Felipe Vilella; Marcos Parras-Molto; Esther Tercero-Atencia; Carlos Simon; Inmaculada Moreno
Opublikowane w: International Journal of Molecular Sciences, 2024, ISSN 1422-0067
Wydawca: International journal of molecular sciences (Online)
DOI: 10.3390/IJMS252312600

Nutrients

Autorzy: Lucía Camacho-Barcia; Isabel Sánchez; Ana Ibáñez-Caparrós; Noriaki Ohsako; Roser Granero; Cristina Artero; José Manuel Crespo; Georgios Paslakis; Susana Jiménez-Murcia; Fernando Fernández-Aranda
Opublikowane w: Nutrients, 2024, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/NU16142337

Central lipid sensing pathways contribute to the control of puberty and its alterations in conditions of obesity

Autorzy: Elvira Rodríguez-Vázquez, Álvaro Aranda-Torrecillas, María López-Sancho, Manuel Jiménez-Puyer, Silvia Daza-Dueñas, Alexia Barroso, Verónica Sobrino, Francisco Gaytan, Elia Obis, Juan M. Castellano, Manuel Tena-Sempere
Opublikowane w: American Journal of Physiology-Endocrinology and Metabolism, Numer 328, 2025, ISSN 0193-1849
Wydawca: American Physiological Society
DOI: 10.1152/AJPENDO.00493.2024

Association between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population

Autorzy: I. Baenas; L. Camacho-Barcia; R. Granero; C. Razquin; D. Corella; C. Gmez-Martnez; O. Castaer-Nio; J. A. Martnez; . M. Alonso-Gmez; J. Wrnberg; J. Vioque; D. Romaguera; J. Lpez-Miranda; R. Estruch; F. J. Tinahones; J. Lapetra; J. L. Serra-Majem; N. Cano-Ibez; J. A. Tur; V. Martn-Snchez; X. Pint; J. J. Gaforio; P. Mata-Martn; J. Vidal; C. Vzquez; L. Daimiel; E. Ros; S. Jimnez-Murcia; S. Dalsgaard; A. Garcia-Arellano; N. Babio; J. V. Sorli; C. Lassale; M. Garca-de-la-Hera; E. Gmez-Garca; M. A. Zulet; J. Konieczna; S. Martn-Pelez; L. Tojal-Sierra; F. J. Basterra-Gortari; S. de las Heras-Delgado; O. Portoles; M. . Muoz-Prez; A. P. Arenas-Larriva; L. Compa-Gabucio; S. Eguaras; S. Shyam; M. Fit; R. M. Baos; J. Salas-Salvad; F. Fernndez-Aranda
Opublikowane w: Journal of Endocrinological Investigation, 2024, ISSN 0000-0000
Wydawca: Scopus 20
DOI: 10.1007/s40618-023-02278-y

Eating disorders and obesity: bridging clinical, neurobiological, and therapeutic perspectives

Autorzy: Lucia Camacho-Barcia, Katrin Elisabeth Giel, Susana Jiménez-Murcia, Julio Álvarez Pitti, Nadia Micali, Ignacio Lucas, Romina Miranda-Olivos, Lucero Munguia, Manuel Tena-Sempere, Stephan Zipfel, Fernando Fernández-Aranda
Opublikowane w: Trends in Molecular Medicine, Numer 30, 2024, ISSN 1471-4914
Wydawca: Elsevier BV
DOI: 10.1016/j.molmed.2024.02.007

Higher peak height velocity in early maturing girls depends on insulin rather than fat mass or IGF-I

Autorzy: Kaspar Sørensen, Casper P Hagen, Anders Juul
Opublikowane w: European Journal of Endocrinology, Numer 191, 2024, ISSN 0804-4643
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/EJENDO/LVAE115

Independent effect of body fat content on inflammatory biomarkers in children and adolescents: The GENOBOX study

Autorzy: Estela Skapino, Laura Gonzalez-Gayan, Miguel Seral-Cortes, Sergio Sabroso-Lasa, Ma Teresa Llorente-Cereza, Rosaura Leis, Concepción M. Aguilera, Mercedes Gil-Campos, Luis A. Moreno, Gloria Bueno-Lozano
Opublikowane w: Nutrition, Metabolism and Cardiovascular Diseases, Numer 35, 2026, ISSN 0939-4753
Wydawca: Elsevier BV
DOI: 10.1016/J.NUMECD.2024.103811

Hypothalamic SIRT1-mediated regulation of the hormonal trigger of ovulation and its repression in energy deficit

Autorzy: María J. Vazquez, Silvia Daza-Dueñas, Inmaculada Velasco, Francisco Ruiz-Pino, María J. Sanchez-Tapia, María Manfredi-Lozano, Carmen Torres-Granados, Alexia Barroso, Juan Roa, Miguel A. Sánchez-Garrido, Carlos Dieguez, Alejandro Lomniczi, Rubén Nogueiras, Manuel Tena-Sempere
Opublikowane w: Metabolism, Numer 164, 2026, ISSN 0026-0495
Wydawca: Elsevier BV
DOI: 10.1016/J.METABOL.2024.156125

The role of motivation in weight reduction programs for children and adolescents with overweight or obesity: a systematic review

Autorzy: Herschbach, Anne; Wels, Annalena; Dieckmann, Pauline; Erschens, Rebecca; Junne, Florian; Ehehalt, Stefan; Zipfel, Stephan; Giel, Katrin Elisabeth; Ziser, Katrin
Opublikowane w: Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 2025, ISSN 1590-1262
Wydawca: Springer Nature
DOI: 10.1007/S40519-025-01763-Y

Association of anandamide and 2-arachidonoylglycerol concentrations with clinical features and body mass index in eating disorders and obesity

Autorzy: Isabel Baenas; Romina Miranda-Olivos; Roser Granero; Neus Sol-Morata; Isabel Snchez; Antoni Pastor; Amparo del Pino-Gutirrez; Ester Codina; Francisco J. Tinahones; Jos A. Fernndez-Formoso; Nria Vilarrasa; Fernando Guerrero-Prez; Rafael Lopez-Urdiales; Nria Virgili; Carles Soriano-Mas; Susana Jimnez-Murcia; Rafael de la Torre; Fernando Fernndez-Aranda
Opublikowane w: European Psychiatry, 2023, ISSN 0000-0000
Wydawca: Cambridge University Press
DOI: 10.1192/j.eurpsy.2023.2411

Hypothalamic control of puberty: from neuronal circuits to mechanisms for its metabolic regulation

Autorzy: Manuel Jimenez-Puyer, Verónica Sobrino, William H. Colledge, Susan Jones, Manuel Tena-Sempere
Opublikowane w: Reviews in Endocrine and Metabolic Disorders, 2025, ISSN 1389-9155
Wydawca: Springer Science and Business Media LLC
DOI: 10.1007/S11154-025-10001-W

Precocious Puberty and Risk of Psychiatric Disorders: A Nationwide Cohort Study Using Prospective Registry Data

Autorzy: Trine Koch Hueg, Youn-Hee Lim, Stine Agergaard Holmboe, Nadia Micali, Anders Juul
Opublikowane w: The Journal of Clinical Endocrinology &amp; Metabolism, Numer 111, 2026, ISSN 0021-972X
Wydawca: The Endocrine Society
DOI: 10.1210/CLINEM/DGAF567

Journal of Behavioral Addictions

Autorzy: Mikel Etxandi; Isabel Baenas; Bernat Mora-Maltas; Roser Granero; Fernando Fernández-Aranda; Sulay Tovar; Neus Solé-Morata; Ignacio Lucas; Sabela Casado; Mónica Gómez-Peña; Laura Moragas; Amparo del Pino-Gutiérrez; Javier Tapia; Eduardo Valenciano-Mendoza; Marc N. Potenza; Ashley N. Gearhardt; Carlos Diéguez; Susana Jiménez-Murcia
Opublikowane w: Journal of Behavioral Addictions, 2023, ISSN 2062-5871
Wydawca: Akademiai Kiado
DOI: 10.1556/2006.2023.00051

Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder

Autorzy: Isabel Baenas; Neus Sol-Morata; Roser Granero; Fernando Fernndez-Aranda; Mitona Pujadas; Bernat Mora-Maltas; Ignacio Lucas; Mnica Gmez-Pea; Laura Moragas; Amparo del Pino-Gutirrez; Javier Tapia; Rafael de la Torre; Marc N. Potenza; Susana Jimnez-Murcia
Opublikowane w: European Psychiatry, 2023, ISSN 0000-0000
Wydawca: Cambridge University Press
DOI: 10.1192/j.eurpsy.2023.2460

Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity

Autorzy: Romina Miranda-Olivos; Isabel Baenas; Trevor Steward; Roser Granero; ANTONI PASTOR; Isabel Snchez; Asier Juaneda; Amparo Del Pino; Jose A. Fernndez-Formoso; Nuria Vilarrasa; Fernando Guerrero-Prez; Nuria Virgili; Rafael Lpez-Urdiales; Susana Jimnez-Murcia; Rafael de la Torre; Carles Soriano-Mas; Fernando Fernandez-Aranda
Opublikowane w: Molecular Psychiatry, 2023, ISSN 0000-0000
Wydawca: Dipòsit Digital de la Universitat de Barcelona
DOI: 10.21203/rs.3.rs-3008676/v1

The Effect of Maternal Diet and Lifestyle on the Risk of Childhood Obesity

Autorzy: Edyta Łuszczki, Justyna Wyszyńska, Agnieszka Dymek, Dorota Drożdż, Laura González-Ramos, Isa Hartgring, Nuria García-Carbonell, Artur Mazur, Serap Erdine, Justė Parnarauskienė, Julio Alvarez-Pitti
Opublikowane w: Metabolites, Numer 14, 2024, ISSN 2218-1989
Wydawca: MDPI AG
DOI: 10.3390/metabo14120655

Multiomics and eXplainable artificial intelligence for decision support in insulin resistance early diagnosis: A pediatric population-based longitudinal study

Autorzy: Álvaro Torres-Martos, Augusto Anguita-Ruiz, Mireia Bustos-Aibar, Alberto Ramírez-Mena, María Arteaga, Gloria Bueno, Rosaura Leis, Concepción M. Aguilera, Rafael Alcalá, Jesús Alcalá-Fdez
Opublikowane w: Artificial Intelligence in Medicine, Numer 156, 2024, ISSN 0933-3657
Wydawca: Elsevier BV
DOI: 10.1016/J.ARTMED.2024.102962

Endocrine nanozymology: Nanozyme applications in diabetes, obesity, and hormonal disorders

Autorzy: Huilun Lu, Zizhong Liu, Ya-chao Wang, Eudald Casals, Felicia A Hanzu, Manuel Morales-Ruiz, Muling Zeng, Gregori Casals
Opublikowane w: Theranostics, Numer 16, 2025, ISSN 1838-7640
Wydawca: Ivyspring International Publisher
DOI: 10.7150/THNO.122577

Biomarker and clinical data–based predictor tool (MAUXI) for ultrafiltration failure and cardiovascular outcome in peritoneal dialysis patients: a retrospective and longitudinal study

Autorzy: Eva María Arriero-País, María Auxiliadora Bajo-Rubio, Roberto Arrojo-García, Pilar Sandoval, Guadalupe Tirma González-Mateo, Patricia Albar-Vizcaíno, Gloria del Peso-Gilsanz, Marta Ossorio-González, Pedro Majano, Manuel López-Cabrera
Opublikowane w: BMJ Health &amp; Care Informatics, Numer 32, 2026, ISSN 2632-1009
Wydawca: BMJ
DOI: 10.1136/BMJHCI-2024-101138

Applying psycho-behavioural phenotyping in obesity characterization

Autorzy: Luca Camacho-Barcia; Ignacio Lucas; Romina Miranda-Olivos; Susana Jimnez-Murcia; Fernando Fernndez-Aranda
Opublikowane w: Reviews in Endocrine and Metabolic Disorders, 2023, ISSN 1573-2606
Wydawca: Springer Nature
DOI: 10.1007/s11154-023-09810-8

Longitudinal assessment of growth velocity in relation to pubertal timing, IGF-1, fasting insulin and fat mass in healthy boys

Autorzy: Kaspar Sørensen, Casper P Hagen, Lise Aksglæde, Rikke Beck Jensen, Anders Juul
Opublikowane w: Endocrine Connections, Numer 15, 2026, ISSN 2049-3614
Wydawca: Bioscientifica
DOI: 10.1530/EC-25-0667

Conference proceedings (1)

Leveraging Machine Learning and Genetic Risk Scores for the Prediction of Metabolic Syndrome in Children with Obesity

Autorzy: Concepcin M. Aguilera; Mireia Bustos-Aibar; Augusto Anguita-Ruiz; lvaro Torres-Martos; Gloria Bueno; Rosaura Leis; Jess Alcal-Fernndez
Opublikowane w: The 14th European Nutrition Conference FENS 2023, 2024
Wydawca: MDPI Proceedings
DOI: 10.3390/proceedings2023091377