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CORDIS - EU research results
CORDIS

Improving understanding of lung immunity in tuberculosis to establish a diverse, innovative TB vaccine pipeline targeting mucosal immunity

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Portfolio Advisory Committee established (opens in new window)

Portfolio advisory committee composed of experts established

NHP biosample repository overview I (opens in new window)

Periodic overview of banked NHP biomaterials available for investigation of host response profiles & biomarkers in WP3

Project Website Established (opens in new window)

Project website and portal site online

Bioinformatics pipeline established (opens in new window)

Bioinformatics pipeline and analysis methodology for spatial sequencing of vaccine-induced cellular responses in the M. tb-infected lung (King team)

Meeting 1 (Kickoff Meeting) (opens in new window)

Kick-off meeting

Press release (opens in new window)

Press release to announce the start of the project

Publications

Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis (opens in new window)

Author(s): Das M K, Savidge B, Pearl J E, Yates T, Miles G, Pareek M, Haldar P, Cooper A M
Published in: PLoS Pathogens, Issue 20, 2024, ISSN 1553-7366
Publisher: Public Library of Science
DOI: 10.1371/journal.ppat.1012565

International Journal of Infectious Diseases (opens in new window)

Author(s): Goletti, D; Matteelli, A; Cliff, JM; Meintjes, G; Graham, S; Esmail, H; Shan Lee, S
Published in: International Journal of Infectious Diseases, 2025, ISSN 1201-9712
Publisher: Elsevier Ltd
DOI: 10.1016/J.IJID.2025.107892

Therapy modulates the response to T cell epitopes over the spectrum of tuberculosis infection (opens in new window)

Author(s): Petrone L, Peruzzu D, Altera AMG, Salmi A, Vanini V, Cuzzi G, Coppola A, Mellini V, Gualano G, Palmieri F, Panda S, Peters B, Sette A, Lindestam Arlehamn C, Goletti D
Published in: Journal of Infection, 2024, ISSN 0163-4453
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/J.JINF.2024.106295

Polycytotoxic T cells mediate antimicrobial activity against intracellular <i>Mycobacterium tuberculosis</i> (opens in new window)

Author(s): Marc Zumwinkel, Aaron Chirambo, Markus Zähnle, Max Bürger, Mark Grieshober, Vincent Romahn, Henry Mwandumba, Steffen Stenger
Published in: Infection and Immunity, Issue 93, 2025, ISSN 0019-9567
Publisher: American Society for Microbiology
DOI: 10.1128/IAI.00297-24

Characterization of QuantiFERON-TB-Plus Results in Patients with Tuberculosis Infection and Multiple Sclerosis (opens in new window)

Author(s): Elisa Petruccioli; Luca Prosperini; Serena Ruggieri; Valentina Vanini; Andrea Salmi; Gilda Cuzzi; Simonetta Galgani; Shalom Haggiag; Carla Tortorella; Gabriella Parisi; Alfio D’Agostino; Gina Gualan
Published in: Neurology International, 2025, ISSN 2035-8377
Publisher: MDPI Basel
DOI: 10.3390/NEUROLINT17080119

Host-directed therapies: old and new approaches for the treatment of infections (opens in new window)

Author(s): Goletti D, Ong C W M, Friedland Jon S
Published in: International Journal of Infectious Diseases, Issue 146, 2024, ISSN 1201-9712
Publisher: Elsevier Sci Ltd
DOI: 10.1016/J.IJID.2024.107130

Comparative Study of [18F]DPA714 and [18F]FDG PET Tracers in an Experimental Model of Pulmonary Tuberculosis (opens in new window)

Author(s): M. A. Stammes, M. P. M. Vierboom, C. C. Sombroek, J. Bakker, L. Meijer, R. A. W. Vervenne, S. O. Hofman, E. Nutma, I. Kondova, A. D. Windhorst, J. A. M. Langermans, F. A. W. Verreck
Published in: Molecular Imaging and Biology, 2025, ISSN 1536-1632
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/S11307-025-02057-6

Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of adults with tuberculosis infection and disease (opens in new window)

Author(s): Repele F, Alonzi T, Navarra A, Farroni C, Salmi A, Cuzzi G, Delogu G, Gualano G, Puro V, De Carli G, Girardi E, Palmieri F, Martineau A R, Goletti D
Published in: International Journal of Infectious Diseases, Issue 141, 2024, ISSN 1201-9712
Publisher: Elsevier Sci Ltd
DOI: 10.1016/J.IJID.2024.106999

Addressing tuberculosis infection: an essential step in the fight against tuberculosis (opens in new window)

Author(s): Santin M, Trajman A, Goletti D, Anibarro L
Published in: Frontiers in Medicine, Issue 11, 2024, ISSN 2296-858X
Publisher: FRONTIERS MEDIA SA
DOI: 10.3389/FMED.2024.1428677

Specific immune response to M. tuberculosis and ability to in vitro control mycobacterial replication are not impaired in subjects with immune-mediated inflammatory disease and tuberculosis infection (opens in new window)

Author(s): Chiara Farroni; Anna Maria Gerarda Altera; Andrea Salmi; Valentina Vanini; Valentina Vanini; Gilda Cuzzi; Cecilia S. Lindestam Arlehamn; Alessandro Sette; Giovanni Delogu; Giovanni Delogu; Ivana Paluc
Published in: Frontiers in Immunology, 2025, ISSN 1664-3224
Publisher: Lausanne Frontiers Media SA
DOI: 10.3389/FIMMU.2024.1484143

Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis (opens in new window)

Author(s): Grifoni A, Alonzi T, Alter G, McClain Noonan D, Landay A L, Albini A, Goletti D
Published in: Frontiers in Immunology, Issue 14:1146704, 2023, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/FIMMU.2023.1146704

International Journal of Infectious Diseases (opens in new window)

Author(s): Tonino Alonzi, Elisa Petruccioli, Alessandra Aiello, Federica Repele, Delia Goletti
Published in: International Journal of Infectious Diseases, Issue 155, 2025, ISSN 1201-9712
Publisher: Elsevier BV
DOI: 10.1016/J.IJID.2025.107880

Seminars in Immunology (opens in new window)

Author(s): Pei Min Thong, Yi Hao Wong, Hardy Kornfeld, Delia Goletti, Catherine W.M. Ong
Published in: Seminars in Immunology, Issue 78, 2025, ISSN 1044-5323
Publisher: Academic Press
DOI: 10.1016/J.SMIM.2025.101959

Drugs for treating infections caused by non-tubercular mycobacteria: a narrative review from the study group on mycobacteria of the Italian Society of Infectious Diseases and Tropical Medicine (opens in new window)

Author(s): Calcagno A, Coppola N, Sarmati L, Tadolini M, Parella R, Mateelli A, Riccardi N, Trezzi M, Di Biagio A, Pirriatore V, Russo A, Gualano G, Pontali E, Surace L, Falbo E, Mencarini J, Palmieri A, Gori A, Schiuma M, Lapadula G, Goletti D
Published in: Infection, Issue 52, 2024, ISSN 0300-8126
Publisher: Urban und Vogel Medien und Medizin Verlagsgesellschaft mbH
DOI: 10.1007/S15010-024-02183-3

World Tuberculosis Day 2024 theme “Yes! We can end TB” can be made a reality through concerted global efforts that advance detection, diagnosis, and treatment of tuberculosis infection and disease (opens in new window)

Author(s): Goletti D, Al-Abri S, Migliori G B, Lindestam Arlehamn C, Haldar P, Sundling C, da Costa C, To K W, Martineau A R, Petersen E, Zumla A, Lee S S
Published in: International Journal of Infectious Diseases, Issue 141, 2024, ISSN 1201-9712
Publisher: Elsevier Sci Ltd
DOI: 10.1016/J.IJID.2024.106993

Exploring the efficacy of MTBVAC as a desensitizing treatment against asthma

Author(s): Silvia Calvo García
Published in: N/A (Univ of Zaragoza internal), 2024
Publisher: Universidad de Zaragoza

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