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CORDIS

Adaptation to climate change in the rhizosphere across the millennia

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Initial list of top-candidate genes for genetic engineering and ancestral reconstitution (opens in new window)

We will provide an initial list of selected top-candidate genes for engineering to introduce climate tolerance traits into selected microorganisms. The results of attempts at ancestral reconstruction of the origin of traits leading to increased tolerance to drought will also be reported. D1.3 is an outcome of Task 1.2 and it is an input for D1.4.

Initial identification of modern relative microorganisms of those identified in the ancient environmental samples (opens in new window)

We will provide an initial report on our comparison of the genomes of archaic drought-adapted taxa with those of modern microorganisms. This can be used to assess adaptation physiological traits and their genetic determinants. D1.5 is an outcome of Task 1.3 and it is an input for D1.6..

Initial lab-scale fermentation and downstream processing development (opens in new window)

We will report on the initial results of the optimization of fermentation at lab-scale for production of engineered rhizosphere bacteria. D4.1 is an outcome of Task 4.1 and it is an input for D4.2.

Project management handbook/guidelines (opens in new window)

We will provide a report regarding operational and structural details of the consortium as per the requirements of the Grant Agreement regarding financial reporting, presentation standards for deliverables and reports to the European Commission, an internal communication plan and an internal review procedure for quality assurance of project results, etc. D8.4 is an outcome of Task 8.2.

Initial analysis of ancient genomes in environmental samples (opens in new window)

We will provide an initial report on target genes selected for genetic engineering as well as microbial taxa and functional genes distinctive for heat/drought conditions. D1.1 is an outcome of Task 1.1 and it is an input for D1.2

Initial plan on communication and dissemination + exploitation (opens in new window)

We will provide a report on initial communication and dissemination plans, events and clustering activities. D7.2 is an outcome of Task 7.2 and it is an input for D7.4.

First version of the data management plan (opens in new window)

We will provide a first report on the data management plan. D8.1 is an outcome of Task 8.1 and it is an input for D8.2.

Publications

Metabolic Origin, Role and Fate of the Denaturant Guanidine (opens in new window)

Author(s): Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You
Published in: Microbial Biotechnology, Issue 18, 2025, ISSN 1751-7915
Publisher: Wiley
DOI: 10.1111/1751-7915.70266

A blueprint for designing the next-generation of synthetic C1 microbes (opens in new window)

Author(s): Giusi Favoino, Òscar Puiggené, Pablo I. Nikel
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-64483-Y

Functional organization and regulatory logic of the <i>ped</i> gene cluster in <i>Pseudomonas</i> species (opens in new window)

Author(s): Òscar Puiggené, Pablo I. Nikel
Published in: Applied and Environmental Microbiology, 2026, ISSN 0099-2240
Publisher: American Society for Microbiology
DOI: 10.1128/AEM.00046-26

FEMS Microbiology Reviews (opens in new window)

Author(s): Òscar Puiggené; Giusi Favoino; Filippo Federici; Michele Partipilo; Enrico Orsi; Maria V G Alván-Vargas; Javier M Hernández-Sancho; Nienke K Dekker; Emil C Ørsted; Eray U Bozkurt; Sara Grassi; Ju
Published in: FEMS Microbiology Reviews, 2025, ISSN 0168-6445
Publisher: Blackwell
DOI: 10.1093/FEMSRE/FUAF011

The disputed identity of <i>Pseudomonas putida</i> KT2440: when taxonomists rename your favorite microbe (opens in new window)

Author(s): Victor de Lorenzo, Danilo Pérez-Pantoja, Juan Luis Ramos, Pablo I. Nikel
Published in: mBio, 2026, ISSN 2150-7511
Publisher: American Society for Microbiology
DOI: 10.1128/MBIO.03390-25

Synthetic C <sub>1</sub> metabolism in <i>Pseudomonas putida</i> enables strict formatotrophy and methylotrophy via the reductive glycine pathway (opens in new window)

Author(s): Justine Turlin, Maria V. G. Alván-Vargas, Òscar Puiggené, Stefano Donati, Sebastian Wenk, Pablo I. Nikel
Published in: mBio, Issue 16, 2025, ISSN 2150-7511
Publisher: American Society for Microbiology
DOI: 10.1128/MBIO.01976-25

Precision Proteolysis of Triosephosphate Isomerase of <i>Escherichia coli</i> Boosts Dihydroxyacetone Phosphate Biosynthesis (opens in new window)

Author(s): Belén Calles, Daniel C. Volke, Max Chavarría, Pablo I. Nikel, Víctor de Lorenzo
Published in: ACS Synthetic Biology, 2026, ISSN 2161-5063
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSSYNBIO.5C00870

Growth-coupled microbial biosynthesis of the animal pigment xanthommatin (opens in new window)

Author(s): Leah B. Bushin, Tobias B. Alter, María V. G. Alván-Vargas, Lara Dürr, Elina C. Olson, Mariah J. Avila, Daniel C. Volke, Òscar Puiggené, Taehwan Kim, Leila F. Deravi, Adam M. Feist, Pablo I. Nikel, Bradley S. Moore
Published in: Nature Biotechnology, 2025, ISSN 1087-0156
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41587-025-02867-7

FEMS Microbiology Reviews (opens in new window)

Author(s): Román A. Martino; Daniel C. Volke; Albano H. Tenaglia; Paula M. Tribelli; Pablo I. Nikel; Andrea M. Smania
Published in: Microbial Biotechnology, 2025
Publisher: Blackwell
DOI: 10.1111/1751-7915.70137

Streamlining the Design‐Build‐Test‐Learn Process in Automated Biofoundries (opens in new window)

Author(s): Enrico Orsi, Nicolás Gurdo, Pablo I. Nikel
Published in: Machine Learning and Big Data‐enabled Biotechnology, 2026
Publisher: Wiley
DOI: 10.1002/9783527850532.CH13

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