Adaptation to climate change in the rhizosphere across the millennia

Projektinformationen

TOLERATE

ID Finanzhilfevereinbarung: 101082049

DOI

10.3030/101082049

EK-Unterschriftsdatum 4 Dezember 2023

Startdatum 1 Dezember 2023

Enddatum 30 November 2027

Finanziert unter

• Food, Bioeconomy Natural Resources, Agriculture and Environment

Gesamtkosten

€ 3 909 870,00

EU-Beitrag

€ 3 909 870,00

Koordiniert durch

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (6)

Initial list of top-candidate genes for genetic engineering and ancestral reconstitution

We will provide an initial list of selected top-candidate genes for engineering to introduce climate tolerance traits into selected microorganisms. The results of attempts at ancestral reconstruction of the origin of traits leading to increased tolerance to drought will also be reported. D1.3 is an outcome of Task 1.2 and it is an input for D1.4.

Initial identification of modern relative microorganisms of those identified in the ancient environmental samples

We will provide an initial report on our comparison of the genomes of archaic drought-adapted taxa with those of modern microorganisms. This can be used to assess adaptation physiological traits and their genetic determinants. D1.5 is an outcome of Task 1.3 and it is an input for D1.6..

Initial lab-scale fermentation and downstream processing development

We will report on the initial results of the optimization of fermentation at lab-scale for production of engineered rhizosphere bacteria. D4.1 is an outcome of Task 4.1 and it is an input for D4.2.

Project management handbook/guidelines

We will provide a report regarding operational and structural details of the consortium as per the requirements of the Grant Agreement regarding financial reporting, presentation standards for deliverables and reports to the European Commission, an internal communication plan and an internal review procedure for quality assurance of project results, etc. D8.4 is an outcome of Task 8.2.

Initial analysis of ancient genomes in environmental samples

We will provide an initial report on target genes selected for genetic engineering as well as microbial taxa and functional genes distinctive for heat/drought conditions. D1.1 is an outcome of Task 1.1 and it is an input for D1.2

Initial plan on communication and dissemination + exploitation

We will provide a report on initial communication and dissemination plans, events and clustering activities. D7.2 is an outcome of Task 7.2 and it is an input for D7.4.

Data Management Plan (1)

First version of the data management plan

We will provide a first report on the data management plan. D8.1 is an outcome of Task 8.1 and it is an input for D8.2.

Websites, patent fillings, videos etc. (1)

Visual identity, website and social media accounts

We will construct a dedicated website. D7.1 is an outcome of Task 7.1.

Veröffentlichungen

Peer reviewed articles (8)

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Autoren: Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You
Veröffentlicht in: Microbial Biotechnology, Ausgabe 18, 2025, ISSN 1751-7915
Herausgeber: Wiley
DOI: 10.1111/1751-7915.70266

A blueprint for designing the next-generation of synthetic C1 microbes

Autoren: Giusi Favoino, Òscar Puiggené, Pablo I. Nikel
Veröffentlicht in: Nature Communications, Ausgabe 16, 2025, ISSN 2041-1723
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-64483-Y

Functional organization and regulatory logic of the <i>ped</i> gene cluster in <i>Pseudomonas</i> species

Autoren: Òscar Puiggené, Pablo I. Nikel
Veröffentlicht in: Applied and Environmental Microbiology, 2026, ISSN 0099-2240
Herausgeber: American Society for Microbiology
DOI: 10.1128/AEM.00046-26

FEMS Microbiology Reviews

Autoren: Òscar Puiggené; Giusi Favoino; Filippo Federici; Michele Partipilo; Enrico Orsi; Maria V G Alván-Vargas; Javier M Hernández-Sancho; Nienke K Dekker; Emil C Ørsted; Eray U Bozkurt; Sara Grassi; Ju
Veröffentlicht in: FEMS Microbiology Reviews, 2025, ISSN 0168-6445
Herausgeber: Blackwell
DOI: 10.1093/FEMSRE/FUAF011

The disputed identity of <i>Pseudomonas putida</i> KT2440: when taxonomists rename your favorite microbe

Autoren: Victor de Lorenzo, Danilo Pérez-Pantoja, Juan Luis Ramos, Pablo I. Nikel
Veröffentlicht in: mBio, 2026, ISSN 2150-7511
Herausgeber: American Society for Microbiology
DOI: 10.1128/MBIO.03390-25

Synthetic C ₁ metabolism in <i>Pseudomonas putida</i> enables strict formatotrophy and methylotrophy via the reductive glycine pathway

Autoren: Justine Turlin, Maria V. G. Alván-Vargas, Òscar Puiggené, Stefano Donati, Sebastian Wenk, Pablo I. Nikel
Veröffentlicht in: mBio, Ausgabe 16, 2025, ISSN 2150-7511
Herausgeber: American Society for Microbiology
DOI: 10.1128/MBIO.01976-25

Precision Proteolysis of Triosephosphate Isomerase of <i>Escherichia coli</i> Boosts Dihydroxyacetone Phosphate Biosynthesis

Autoren: Belén Calles, Daniel C. Volke, Max Chavarría, Pablo I. Nikel, Víctor de Lorenzo
Veröffentlicht in: ACS Synthetic Biology, 2026, ISSN 2161-5063
Herausgeber: American Chemical Society (ACS)
DOI: 10.1021/ACSSYNBIO.5C00870

Growth-coupled microbial biosynthesis of the animal pigment xanthommatin

Autoren: Leah B. Bushin, Tobias B. Alter, María V. G. Alván-Vargas, Lara Dürr, Elina C. Olson, Mariah J. Avila, Daniel C. Volke, Òscar Puiggené, Taehwan Kim, Leila F. Deravi, Adam M. Feist, Pablo I. Nikel, Bradley S. Moore
Veröffentlicht in: Nature Biotechnology, 2025, ISSN 1087-0156
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/S41587-025-02867-7

Other (1)

FEMS Microbiology Reviews

Autoren: Román A. Martino; Daniel C. Volke; Albano H. Tenaglia; Paula M. Tribelli; Pablo I. Nikel; Andrea M. Smania
Veröffentlicht in: Microbial Biotechnology, 2025
Herausgeber: Blackwell
DOI: 10.1111/1751-7915.70137

Book chapters (1)

Streamlining the Design‐Build‐Test‐Learn Process in Automated Biofoundries

Autoren: Enrico Orsi, Nicolás Gurdo, Pablo I. Nikel
Veröffentlicht in: Machine Learning and Big Data‐enabled Biotechnology, 2026
Herausgeber: Wiley
DOI: 10.1002/9783527850532.CH13