Adaptation to climate change in the rhizosphere across the millennia

Informations projet

TOLERATE

N° de convention de subvention: 101082049

DOI

10.3030/101082049

Date de signature de la CE 4 Decembre 2023

Date de début 1 Decembre 2023

Date de fin 30 Novembre 2027

Financé au titre de

• Food, Bioeconomy Natural Resources, Agriculture and Environment

Coût total

€ 3 909 870,00

Contribution de l’UE

€ 3 909 870,00

Coordonné par

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (6)

Initial list of top-candidate genes for genetic engineering and ancestral reconstitution

We will provide an initial list of selected top-candidate genes for engineering to introduce climate tolerance traits into selected microorganisms. The results of attempts at ancestral reconstruction of the origin of traits leading to increased tolerance to drought will also be reported. D1.3 is an outcome of Task 1.2 and it is an input for D1.4.

Initial identification of modern relative microorganisms of those identified in the ancient environmental samples

We will provide an initial report on our comparison of the genomes of archaic drought-adapted taxa with those of modern microorganisms. This can be used to assess adaptation physiological traits and their genetic determinants. D1.5 is an outcome of Task 1.3 and it is an input for D1.6..

Initial lab-scale fermentation and downstream processing development

We will report on the initial results of the optimization of fermentation at lab-scale for production of engineered rhizosphere bacteria. D4.1 is an outcome of Task 4.1 and it is an input for D4.2.

Project management handbook/guidelines

We will provide a report regarding operational and structural details of the consortium as per the requirements of the Grant Agreement regarding financial reporting, presentation standards for deliverables and reports to the European Commission, an internal communication plan and an internal review procedure for quality assurance of project results, etc. D8.4 is an outcome of Task 8.2.

Initial analysis of ancient genomes in environmental samples

We will provide an initial report on target genes selected for genetic engineering as well as microbial taxa and functional genes distinctive for heat/drought conditions. D1.1 is an outcome of Task 1.1 and it is an input for D1.2

Initial plan on communication and dissemination + exploitation

We will provide a report on initial communication and dissemination plans, events and clustering activities. D7.2 is an outcome of Task 7.2 and it is an input for D7.4.

Data Management Plan (1)

First version of the data management plan

We will provide a first report on the data management plan. D8.1 is an outcome of Task 8.1 and it is an input for D8.2.

Websites, patent fillings, videos etc. (1)

Visual identity, website and social media accounts

We will construct a dedicated website. D7.1 is an outcome of Task 7.1.

Publications

Peer reviewed articles (8)

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Auteurs: Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You
Publié dans: Microbial Biotechnology, Numéro 18, 2025, ISSN 1751-7915
Éditeur: Wiley
DOI: 10.1111/1751-7915.70266

A blueprint for designing the next-generation of synthetic C1 microbes

Auteurs: Giusi Favoino, Òscar Puiggené, Pablo I. Nikel
Publié dans: Nature Communications, Numéro 16, 2025, ISSN 2041-1723
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-64483-Y

Functional organization and regulatory logic of the <i>ped</i> gene cluster in <i>Pseudomonas</i> species

Auteurs: Òscar Puiggené, Pablo I. Nikel
Publié dans: Applied and Environmental Microbiology, 2026, ISSN 0099-2240
Éditeur: American Society for Microbiology
DOI: 10.1128/AEM.00046-26

FEMS Microbiology Reviews

Auteurs: Òscar Puiggené; Giusi Favoino; Filippo Federici; Michele Partipilo; Enrico Orsi; Maria V G Alván-Vargas; Javier M Hernández-Sancho; Nienke K Dekker; Emil C Ørsted; Eray U Bozkurt; Sara Grassi; Ju
Publié dans: FEMS Microbiology Reviews, 2025, ISSN 0168-6445
Éditeur: Blackwell
DOI: 10.1093/FEMSRE/FUAF011

The disputed identity of <i>Pseudomonas putida</i> KT2440: when taxonomists rename your favorite microbe

Auteurs: Victor de Lorenzo, Danilo Pérez-Pantoja, Juan Luis Ramos, Pablo I. Nikel
Publié dans: mBio, 2026, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/MBIO.03390-25

Synthetic C ₁ metabolism in <i>Pseudomonas putida</i> enables strict formatotrophy and methylotrophy via the reductive glycine pathway

Auteurs: Justine Turlin, Maria V. G. Alván-Vargas, Òscar Puiggené, Stefano Donati, Sebastian Wenk, Pablo I. Nikel
Publié dans: mBio, Numéro 16, 2025, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/MBIO.01976-25

Precision Proteolysis of Triosephosphate Isomerase of <i>Escherichia coli</i> Boosts Dihydroxyacetone Phosphate Biosynthesis

Auteurs: Belén Calles, Daniel C. Volke, Max Chavarría, Pablo I. Nikel, Víctor de Lorenzo
Publié dans: ACS Synthetic Biology, 2026, ISSN 2161-5063
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSSYNBIO.5C00870

Growth-coupled microbial biosynthesis of the animal pigment xanthommatin

Auteurs: Leah B. Bushin, Tobias B. Alter, María V. G. Alván-Vargas, Lara Dürr, Elina C. Olson, Mariah J. Avila, Daniel C. Volke, Òscar Puiggené, Taehwan Kim, Leila F. Deravi, Adam M. Feist, Pablo I. Nikel, Bradley S. Moore
Publié dans: Nature Biotechnology, 2025, ISSN 1087-0156
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41587-025-02867-7

Other (1)

FEMS Microbiology Reviews

Auteurs: Román A. Martino; Daniel C. Volke; Albano H. Tenaglia; Paula M. Tribelli; Pablo I. Nikel; Andrea M. Smania
Publié dans: Microbial Biotechnology, 2025
Éditeur: Blackwell
DOI: 10.1111/1751-7915.70137

Book chapters (1)

Streamlining the Design‐Build‐Test‐Learn Process in Automated Biofoundries

Auteurs: Enrico Orsi, Nicolás Gurdo, Pablo I. Nikel
Publié dans: Machine Learning and Big Data‐enabled Biotechnology, 2026
Éditeur: Wiley
DOI: 10.1002/9783527850532.CH13