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Comprehensive and personalized assessment of acute coronary syndrome by multiomic approach and artificial intelligence strategy

Objective

The CardioSCOPE proposal aims to bring together experts from Companies and Αcademia throughout Europe to exchange and expand their expertise on interdisciplinary approaches, to enhance the Research and Innovation capacity of Europe in the field of cardiovascular diseases. Connecting and expanding Europe-wide biobanks and expertise through a comprehensive multiomics approach for the discovery of novel pathological players, CardioSCOPE will give deeper insights into acute coronary syndrome (ACS) development and progression towards major adverse cardiovascular events (MACE). We will use well-defined prospective cohorts to discover and validate novel genomic, transcriptomic, proteomic and metabolomic signatures specific for ACS and MACE, to be combined in multimarker models by machine learning/artificial intelligence algorithms, enabling more accurate ACS diagnosis and MACE prediction. This excellent research network aims at building scientists competent for the upcoming “omics” era by training and knowledge transfer. Specific research skills not available at home institutions will be acquired through individually designed secondment plans, training schools, webinars and short-term courses. Intersectoral activities will improve entrepreneurial skills of consortium staff and facilitate transformation of scientific breakthroughs into commercially available products/services. CardioSCOPE includes experts with a wide clinical and research experience, access to patients with ACS and the expertise required for achieving set goals. World-class institutions gathered within this consortium (from 6 countries: 7 academic, 4 companies, 1 hospital) offer specific expertise, state-of-the-art equipment and adequate human resources to address these challenges. In summary, the results of this project will transcend our own scientific interests to enable a transfer of knowledge into a multidisciplinary environment and achieving significant impact on ACS management and policies in Europe.

Coordinator

UNIVERSITA DEGLI STUDI DI MILANO
Net EU contribution
€ 156 400,00
Address
Via Festa Del Perdono 7
20122 Milano
Italy

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Region
Nord-Ovest Lombardia Milano
Activity type
Higher or Secondary Education Establishments
Other funding
No data

Participants (10)

FARMACEUTSKI FAKULTET UNIVERZITETA U BEOGRADU
Serbia
Net EU contribution
€ 280 600,00
Address
Vojvode Stepe 450
11010 Belgrade

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Region
Србија - север Београдски регион Београдска област
Activity type
Higher or Secondary Education Establishments
Other funding
No data
MULTIMEDICA SPA
Italy
Net EU contribution
€ 115 000,00
Address
Via Fantoli Gaudenzio 16/15
20138 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
FONDAZIONE BRUNO KESSLER
Italy
Net EU contribution
€ 156 400,00
Address
Via Santa Croce 77
38122 Trento

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Region
Nord-Est Provincia Autonoma di Trento Trento
Activity type
Research Organisations
Other funding
No data
B.S.N. BIOLOGICAL SALES NETWORKS.R.L.
Italy
Net EU contribution
€ 50 600,00
Address
Via Coelli 16/18
26012 Castelleone

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Region
Nord-Ovest Lombardia Cremona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
UNIVERSITAT ROVIRA I VIRGILI
Spain
Net EU contribution
€ 41 400,00
Address
Carrer De Escorxador
43003 Tarragona

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Region
Este Cataluña Tarragona
Activity type
Higher or Secondary Education Establishments
Other funding
No data
BIOSFER TESLAB SL
Spain
Net EU contribution
€ 78 200,00
Address
Avinguda Universitat 1
43204 Reus

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Region
Este Cataluña Tarragona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
PANEPISTIMIO KRITIS
Greece
Net EU contribution
€ 225 400,00
Address
University Campus Gallos
74100 Rethimno

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Region
Ρέθυμνο Κρήτη Νησιά Αιγαίου
Activity type
Higher or Secondary Education Establishments
Other funding
No data
GENETIC LAB SRL
Romania
Net EU contribution
€ 41 400,00
Address
Strada Milcov 5 Cladirea C19 Camera 4
012244 Bucharest

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Macroregiunea Trei Bucureşti-Ilfov Bucureşti
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY 'NICOLAE SIMIONESCU' - ROMANIAN ACADEMY
Romania
Net EU contribution
€ 299 000,00
Address
Hasdeu Street
050568 Bucharest

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Region
Macroregiunea Trei Bucureşti-Ilfov Bucureşti
Activity type
Research Organisations
Other funding
No data
KLINICKO-BOLNICKI CENTAR DR DRAGISA MISOVIC-DEDINJE
Serbia
Net EU contribution
€ 73 600,00
Address
Heroja Milana Tepica 1
11000 Beograd

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Region
Србија - север Београдски регион Београдска област
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
No data

Partners (1)

UNIVERSITY OF ULSTER
United Kingdom
Net EU contribution
€ 0,00
Address
Cromore Road
BT52 1SA Coleraine

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Region
Northern Ireland Northern Ireland Causeway Coast and Glens
Activity type
Higher or Secondary Education Establishments
Other funding
No data