Project description DEENESFRITPL Multiomics approach for acute coronary syndrome diagnosis Acute coronary syndrome (ACS) is a medical emergency that can develop into major adverse cardiovascular events (MACE). The EU-funded CardioSCOPE project will bring together experts from academia and companies to exchange and expand expertise on interdisciplinary approaches in cardiovascular diseases through a comprehensive multiomics approach. The project targets the discovery of novel pathological players to provide further knowledge into ACS development and progression toward MACE. CardioSCOPE will use well-defined prospective cohorts to discover and validate novel genomic, transcriptomic, proteomic, and metabolomic signatures and use an ML and AI strategy to deliver more accurate diagnosis and prediction. The project will also train scientists competent for the upcoming ‘omics’ era. Show the project objective Hide the project objective Objective The CardioSCOPE proposal aims to bring together experts from Companies and Αcademia throughout Europe to exchange and expand their expertise on interdisciplinary approaches, to enhance the Research and Innovation capacity of Europe in the field of cardiovascular diseases. Connecting and expanding Europe-wide biobanks and expertise through a comprehensive multiomics approach for the discovery of novel pathological players, CardioSCOPE will give deeper insights into acute coronary syndrome (ACS) development and progression towards major adverse cardiovascular events (MACE). We will use well-defined prospective cohorts to discover and validate novel genomic, transcriptomic, proteomic and metabolomic signatures specific for ACS and MACE, to be combined in multimarker models by machine learning/artificial intelligence algorithms, enabling more accurate ACS diagnosis and MACE prediction. This excellent research network aims at building scientists competent for the upcoming “omics” era by training and knowledge transfer. Specific research skills not available at home institutions will be acquired through individually designed secondment plans, training schools, webinars and short-term courses. Intersectoral activities will improve entrepreneurial skills of consortium staff and facilitate transformation of scientific breakthroughs into commercially available products/services. CardioSCOPE includes experts with a wide clinical and research experience, access to patients with ACS and the expertise required for achieving set goals. World-class institutions gathered within this consortium (from 6 countries: 7 academic, 4 companies, 1 hospital) offer specific expertise, state-of-the-art equipment and adequate human resources to address these challenges. In summary, the results of this project will transcend our own scientific interests to enable a transfer of knowledge into a multidisciplinary environment and achieving significant impact on ACS management and policies in Europe. Fields of science medical and health sciencesclinical medicinecardiologycardiovascular diseasesnatural sciencescomputer and information sciencesartificial intelligencemachine learning Programme(s) HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme Topic(s) HORIZON-MSCA-2021-SE-01-01 - MSCA Staff Exchanges 2021 Call for proposal HORIZON-MSCA-2021-SE-01 See other projects for this call Funding Scheme HORIZON-AG-UN - HORIZON Unit Grant Coordinator UNIVERSITA DEGLI STUDI DI MILANO Net EU contribution € 156 400,00 Address Via festa del perdono 7 20122 Milano Italy See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (10) Sort alphabetically Sort by Net EU contribution Expand all Collapse all FARMACEUTSKI FAKULTET UNIVERZITETA U BEOGRADU Serbia Net EU contribution € 280 600,00 Address Vojvode stepe 450 11010 Belgrade See on map Region Србија - север Београдски регион Београдска област Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MULTIMEDICA SPA Italy Net EU contribution € 115 000,00 Address Via fantoli gaudenzio 16/15 20138 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FONDAZIONE BRUNO KESSLER Italy Net EU contribution € 156 400,00 Address Via santa croce 77 38122 Trento See on map Region Nord-Est Provincia Autonoma di Trento Trento Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 B.S.N. BIOLOGICAL SALES NETWORKS.R.L. Italy Net EU contribution € 50 600,00 Address Via coelli 16/18 26012 Castelleone See on map Region Nord-Ovest Lombardia Cremona Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAT ROVIRA I VIRGILI Spain Net EU contribution € 41 400,00 Address Carrer de escorxador 43003 Tarragona See on map Region Este Cataluña Tarragona Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BIOSFER TESLAB SL Spain Net EU contribution € 78 200,00 Address Avinguda universitat 1 43204 Reus See on map Region Este Cataluña Tarragona Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 PANEPISTIMIO KRITIS Greece Net EU contribution € 225 400,00 Address University campus gallos 74100 Rethimno See on map Region Νησιά Αιγαίου Κρήτη Ρέθυμνο Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 GENETIC LAB SRL Romania Net EU contribution € 41 400,00 Address Strada milcov 5 cladirea c19 camera 4 012244 Bucharest See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Macroregiunea Trei Bucureşti-Ilfov Bucureşti Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY 'NICOLAE SIMIONESCU' - ROMANIAN ACADEMY Romania Net EU contribution € 299 000,00 Address Hasdeu street 050568 Bucharest See on map Region Macroregiunea Trei Bucureşti-Ilfov Bucureşti Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 KLINICKO-BOLNICKI CENTAR DR DRAGISA MISOVIC-DEDINJE Serbia Net EU contribution € 73 600,00 Address Heroja milana tepica 1 11000 Beograd See on map Region Србија - север Београдски регион Београдска област Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITY OF ULSTER United Kingdom Net EU contribution € 0,00 Address Cromore road BT52 1SA Coleraine See on map Region Northern Ireland Northern Ireland Causeway Coast and Glens Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00