Description du projet
Les lectines et les polyphénols des algues pourraient contribuer à vaincre les virus
Les microalgues sont de minuscules usines dont les voies métaboliques complexes produisent de nombreux composés bioactifs présentant un intérêt pour les industries médicales et pharmaceutiques. Parmi ceux-ci figurent les lectines et les polyphénols, connus pour diverses propriétés sanitaires et protectrices, antifongiques, antioxydantes et anti-inflammatoires. Plus récemment, de nombreuses lectines et polyphénols se sont avérés avoir une activité antivirale. Avec le soutien du programme Actions Marie Sklodowska-Curie, le projet AlgaeNet4AV constituera un réseau de formation destiné à étudier et à exploiter les lectines et polyphénols de microalgues dotés de propriétés antivirales contre les souches pandémiques de grippe et de coronavirus. Le projet couvrira la découverte, la caractérisation, le développement de systèmes de culture, l’évaluation du marché, la conception de bioraffineries et l’évaluation technico-économique et de durabilité.
Objectif
The AlgaeNet4AV project seeks to exploit the microalgae biodiversity, as a source for high-added-value lectins and polyphenols with antiviral properties against influenza and coronavirus pandemic strains. Microalgae derived-compounds are easily amendable, bio-degradable, non-toxic and safe; thus, they are preferred to be used for the development of novel bio-based materials and cosmetics with antiviral potential. Lectins and polyphenols could be highly demanded non-drug interventions across the materials and cosmetics industry as a solution to reduce the risk and speed of contamination and transmission during pandemic outbreaks. The project will combine the whole value chain in order to: a) develop transcriptomics and metabolomics resources from microalgae diversity as a valuable source for the discovery novel lectins and polyphenols; b) characterize their spectrum of bioactivity and toxicity and provide structure-function relationships; c) develop and optimize application-based microalgae culture systems and downstream processing strategies for higher production rate of the desired compounds; d) develop, formulate and evaluate lectins and polyphenols-based final cosmetics products. The work will be supported by market assessment, integral biorefinery designs, techno-economic and sustainability assessment. Integrated value chains will be demonstrated to deliver proof-of-concept and demonstrate economic feasibility. AlgaeNet4AV is an industry-academia R&D and innovation project with a multidisciplinary approach aimed at generating robust business cases through technology development. The consortium composed by 11 partners, with 7 European and 2 third-country (USA & Japan) prominent research organisations. Strong industrial leadership is guaranteed through the participation of 5 SMEs. The projects goals will be achieved through a sustainable way helping meet the increasing demand while creating a positive environmental impact through reduction of carbon emissions.
Champ scientifique
Mots‑clés
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Régime de financement
HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff ExchangesCoordinateur
57001 Thermi Thessaloniki
Grèce