Regional Center of Excellence at the Orbeli Institute of Physiology

Informazioni relative al progetto

NAR-SAR-IPH

ID dell’accordo di sovvenzione: 101087403

DOI

10.3030/101087403

Data della firma CE 24 Ottobre 2022

Data di avvio 1 Dicembre 2022

Data di completamento 30 Novembre 2027

Finanziato da

• Widening participation and spreading excellence

Costo totale

€ 2 415 000,00

Contributo UE

€ 2 415 000,00

Coordinato da

L.A .ORBELI INSTITUTE OF PHYSIOLOGYOF THE NATIONAL ACADEMY OF SCIENCESOF THE REPUBLIC OF ARMENIA STATE NON COMMERCIAL ORGANIZATION
Armenia

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (6)

Report on ERA Chair support units structure and profile

This will include a description of the planning of the GSSW and ECC Units structure; preparing the staff job descriptions; advertising the positions and final selection from the applicants.

Education and training programmes and curricula

We are going to develop education curricula based on bioimaging and TERM-related fields (a 3-credit hour/one-semester course and/or a one-month crash course in advanced biomedical imaging techniques).

Data Management Plan

DMP will be developed in accordance with the Open Science and Research Data Management principles, and during the project, implementation will be upadeted twice: M30 and M60.

Appointment of the leader of the newly created research group

Appointment of the leader of the newly created research group on the permanent position in the host Institute.

Move of the ERA Chair to the host institution

The move of the ERA Chair to the IPH.

Report on ERA Chair scientific team structure and profile

The assembling by ERA Chair of the research group and the necessary support units. It is expected that the process of gathering a properly qualified research team will take about 2 years from the appointment of the ERA Chair, apart from the visiting international scholars, who will come on availability and needs basis.

Demonstrators, pilots, prototypes (4)

Conferences and workshops

This activity will include a number of scientific events starting from the Kick-off meeting of high-level professionals to foster the ERA Chair team recruitment and followed by a dedicated series of bi-annual research and innovation conferences, and workshops on TERM one per year. Also, the Final Dissemination event should be organized at the very end of the project by M58.

Publication of Academic and Educational materials

This will include all disseminating research outputs through participation in international conferences, high-impact publications in journals, organization of seminars for academics, lectures for the wide public, and information days for key stakeholders. Update, on a regular basis, the IPH webpage and all associated social media channels with the activities and output of the ERA Chair’s research team. The first set of publications would be summarized by M24, and further on by M36 and M60.

Dissemination materials

This will include the elaboration of dissemination materials and their updates by M18 and M36 of the project.

Bilingual textbook of learning materials

Under guidance by the ERA Chair a manual of key biomedical imaging techniques and protocols will be put together in both English and Armenian.

Pubblicazioni

Peer reviewed articles (8)

Ultrastructural Remodeling of Cardiomyocytes in Postinfarction Myocardium of Rats in the Late Stages of the Disease

Autori: Sergei A. Fedotov, Andrei V. Stepanov, Galina A. Sakuta, Ivan S. Andreev, Marina S. Ivanova, Ekaterina V. Baidyuk
Pubblicato in: Cytometry Part A, Numero 107, 2025, ISSN 1552-4922
Editore: Wiley
DOI: 10.1002/CYTO.A.24915

Changes in attachment and metabolic activity of rat neonatal cardiomyocytes and nonmyocytes caused by Macrovipera lebetina obtusa venom

Autori: Hovhannes Arestakesyan, Narine LeFevre, Nikki Posnack, Arni Sarian, Vahan Grigoryan, Naira Ayvazyan, Armen Voskanyan, Narine Sarvazyan, Zaruhi Karabekian
Pubblicato in: Toxicology in Vitro, Numero 95, 2025, ISSN 0887-2333
Editore: Elsevier BV
DOI: 10.1016/J.TIV.2023.105755

Bolus MPTP Injection in Aged Mice to Mimic Parkinson Disease: Effects of Low-Dose Antioxidant Treatment with Fullerene (C60) and Fullerenol (C60(OH)24)

Autori: Tatyana Strekalova, Alisa Burova, Anna Gorlova, Kirill Chaprov, Anastasia Khizeva, Joana E. Coelho, Evgeniy Svirin, Polina Novikova, Lia Ohanyan, Johannes J. M. P. de Munter, Naira Ayvazyan, Luisa V. Lopes, Aleksei Umriukhin, Gohar Arajyan, Harry W. M. Steinbusch
Pubblicato in: Biomedicines, Numero 13, 2025, ISSN 2227-9059
Editore: MDPI AG
DOI: 10.3390/BIOMEDICINES13102425

Hematological and coagulation alterations and splenic response following Macrovipera lebetina obtusa envenomation: Evaluation of ovine-derived experimental antivenom

Autori: Gevorg Avagyan, Vardan Dabaghyan, Heghine Khachatryan, Ashot Aslanyan, Arsen Kishmiryan, Anna Karapetyan, Naira Ayvazyan
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 19, 2025, ISSN 1935-2735
Editore: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PNTD.0013724

Histopathological changes of mice tissues in course of the envenomation by the Macrovipera lebetina obtusa venom and the neutralizing effect of the ovine-derived experimental antivenom

Autori: Gevorg Avagyan, Hasmik Yeranosyan, Arsen Kishmiryan, Ruzanna Shushanyan, Arthur Melkonian, Naira M. Ayvazyan
Pubblicato in: Toxicon, Numero 247, 2024, ISSN 0041-0101
Editore: Elsevier BV
DOI: 10.1016/J.TOXICON.2024.107821

Comparative Analysis of Deep Learning Methods for Classification of Ablated Regions in Hyperspectral Images of Atrial Tissue

Autori: Yeva Gabrielyan, Arpi Hunanyan, Sona Bezirganyan, Lusine Davtyan, Ani Avetisyan, Narine Sarvazyan, Aram Butavyan, Varduhi Yeghiazaryan
Pubblicato in: IEEE Access, Numero 13, 2025, ISSN 2169-3536
Editore: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/ACCESS.2025.3543122

Macrovipera lebetinus obtusa Venom and Its Fractions Affect Human Dermal Microvascular Endothelial and Fibrosarcoma Cells

Autori: Narine Ghazaryan, Lars Van Werven, Thomas Liepold, Olaf Jahn, Luis A. Pardo, Naira Ayvazyan
Pubblicato in: International Journal of Molecular Sciences, Numero 26, 2025, ISSN 1422-0067
Editore: MDPI AG
DOI: 10.3390/IJMS26083601

Surface Acoustic Waves-Based Molecular Recognition of a Collagen Receptor on Human Erythrocytes

Autori: Gevorg Ghukasyan, Narine Ghazaryan, Michael Torosyan, Naira Movsisyan, Ashot Meltonyan, Naira Ayvazyan
Pubblicato in: International Journal of Molecular Sciences, Numero 26, 2025, ISSN 1422-0067
Editore: MDPI AG
DOI: 10.3390/IJMS262311258

Conference proceedings (3)

Combining 4D Hyperspectral Imaging With CNN for Nerve and Ligament Differentiation

Autori: Naira Matosyan, Narek Chilingaryan, Narine Sarvazyan, Varduhi Yeghiazaryan
Pubblicato in: 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI), 2025
Editore: IEEE
DOI: 10.1109/ISBI60581.2025.10981284

4D hyperspectral imaging for intraoperative tissue classification

Autori: Narek Chilingaryan, Fernando Villarruel, Tigran Soghomonyan, Varduhi Yeghiazaryan, Narine Sarvazyan
Pubblicato in: Medical Imaging 2025: Clinical and Biomedical Imaging, 2025
Editore: SPIE
DOI: 10.1117/12.3047177

Spectral pixels as images: CNN-based pixel classification of 4D hyperspectral data for nerve and ligament differentiation

Autori: Naira Matosyan, Narek Chilingaryan, Narine Sarvazyan, Varduhi Yeghiazaryan
Pubblicato in: Medical Imaging 2025: Image Processing, 2025
Editore: SPIE
DOI: 10.1117/12.3047194