Maximising Impact of Prescription Drugs in Rheumatoid Arthritis

Informazioni relative al progetto

SQUEEZE

ID dell’accordo di sovvenzione: 101095052

DOI

10.3030/101095052

Data della firma CE 25 Novembre 2022

Data di avvio 1 Dicembre 2022

Data di completamento 30 Novembre 2027

Finanziato da

• Health

Costo totale

€ 9 197 602,50

Contributo UE

€ 9 197 602,50

Coordinato da

MEDIZINISCHE UNIVERSITAET WIEN
Austria

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (11)

Descriptive map of TTV values
Ethics and Governance framework

Building the framework for ethics and governance

First submission package of RA-DRUM trial
Report on Associations between serum drug levels and anti-drug antibodies and clinical outcomes
Report on Data platform, warehousing and data & script sharing
Updated Plan on dissemination, exploitation and communication (DEC) of results

This deliverable gives an overview of the planned DEC activities for the project- including planned events and activities, and a first version of communication documents and templates- and a collection of PPTs that can be used as a basis for presentation of Squeeze. The PPTs and templates collected on the Squeeze online portal (for consortium only) will be updated as needed. The report includes website implementation in a first version (including public information/PPTs) and social media (current plan is focusing on LinkedIn and Twitter) initiated.

Risk assessment Report, study monitoring will be carried out throughout the trial with end of study report

First submission package BioBest Trial

Report on SQUEEZE stakeholder strategy
Conclusions from the Kick-off Meeting

Summary reporting of Kick-off meeting

First submission package of MethMax trial; reporting of MTX responder dynamics

First submission package of MethMax trial and reporting of MTX responder dynamics to inform trial

Report with contextual analysis - Map of practice patterns of RA care, use of precision medicine approaches

Websites, patent fillings, videos etc. (1)

public web site

Pubblicazioni

Peer reviewed articles (4)

Time-independent disease state identification defines distinct trajectories determined by localised vs systemic inflammation in patients with early rheumatoid arthritis

Autori: Nils Steinz, Tjardo D. Maarseveen, Erik B. van den Akker, Andrew P. Cope, John D. Isaacs, Aaron R. Winkler, Tom W. J. Huizinga, Yann Abraham, Rachel Knevel
Pubblicato in: Annals of the Rheumatic Diseases, Numero 84, 2025, ISSN 0003-4967
Editore: Elsevier BV
DOI: 10.1016/J.ARD.2025.04.011

Location and amount of joint involvement differentiates rheumatoid arthritis into different clinical subsets

Autori: Tjardo D. Maarseveen; Marc P. Maurits; Lavinia Agra Coletto; Simone Perniola; Stefan Böhringer; Nils Steinz; Sytske Anne Bergstra; Dario Bruno; Maria Rita Gigante; Viviana A. Pacucci; Luca Petricca; Bianca Boxma-de Klerk; Herman Kasper Glas; Clara Di Mario; Denise Campobasso; Barbara Tolusso; Josien Veris-van Dieren; Annette H. M. Helm-van Mil; Elisa Gremese; Maria Antonietta D’Agostino; Marcel J T. Reinders; Marco Gessi; Tom W J Huizinga; Stefano Alivernini; Erik B. Akker; Rachel Knevel
Pubblicato in: npj Digital Medicine, 2025, ISSN 2398-6352
Editore: Springer Nature
DOI: 10.1038/S41746-025-01997-1

Proactive therapeutic drug monitoring of biologic drugs in adult patients with inflammatory bowel disease, inflammatory arthritis, or psoriasis: a clinical practice guideline

Autori: Kawano-Dourado, Leticia; Kristianslund, Eirik Klami; Zeraatkar, Dena; Jani, Meghna; Makharia, Govind; Hazlewood, Glen; Smith, Catherine; Jess, Tine; Stabell, Camilla; Schatten, Arne; Owen, Andrew; Gehin, Johanna; Katsidzira, Leolin; Weinberg, David; Bauer-Ventura, Iazsmin; Tugwell, Peter; Moayyedi, Paul; Cecchi, Ana Veronica Wolff; Shimabuco, Andrea; Seterelv, Siri; Gyuatt, Gordon; Agoritsas, Thomas; Vandvik, Per Olav
Pubblicato in: BMJ, 2024, ISSN 1756-1833
Editore: BMJ Publishing Group Ltd
DOI: 10.1136/BMJ-2024-079830

Therapeutic serum level for adalimumab in rheumatoid arthritis: explorative analyses of data from a randomised phase III trial

Autori: Johanna Elin Gehin; Rolf Anton Klaasen; Eirik Klami Kristianslund; Ingrid Jyssum; Joseph Sexton; David John Warren; Daniel Aletaha; Espen Andre Haavardsholm; Silje Watterdal Syversen; Guro Løvik Goll; Nils Bolstad
Pubblicato in: RMD Open, 2024, ISSN 2056-5933
Editore: BMJ Publishing Group
DOI: 10.1136/RMDOPEN-2024-004888