Systemic Endotoxemia as the driver of chronic inflammation - Biomarkers and novel therapeutic targets for Arthritis

Project Information

ENDOTARGET

Grant agreement ID: 101095084

DOI

10.3030/101095084

EC signature date 15 November 2022

Start date 1 January 2023

End date 31 December 2026

Funded under

• Health

Total cost

€ 6 997 820,00

EU contribution

€ 6 997 820,00

Coordinated by

HUS-YHTYMA
Finland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (3)

First version of dissemination and communication plan

Outline of Endotarget’s dissemination and communication strategy including planned D&C activities.

Project handbook

All relevant project related information for the consortium will be collected in project handbookIt includes general information of agreements project organizational structure communication and dissemination practices internal reviewprocess of deliverables and payments for example

Risk Management plan

Deliverable will include the processes, tools and procedures that will be used to manage and control those events within the Endotarget project that could have a negative impact. It will expose the proposed risk management approach of the project for managing and controlling all project risks. Deliverable will be updated throughout the project.

Data Management Plan (1)

Data Management Plan

Data Management Plan (DMP) of Endotarget’s is to identify the project’s research data and to describe how to make them findable, accessible, interoperable and re-usable (FAIR)

Publications

Peer reviewed articles (9)

β Boswellic Acid Blocks Articular Innate Immune Responses: An In Silico and In Vitro Approach to Traditional Medicine

Author(s): Eloi Franco-Trepat; Ana Alonso-Pérez; María Guillán-Fresco; Miriam López-Fagúndez; Andrés Pazos-Pérez; Antía Crespo-Golmar; Susana Belén Bravo; Verónica López-López; Alberto Jorge-Mora; José P. Cerón-Carrasco; Ana Lois Iglesias; Rodolfo Gómez
Published in: Antioxidants, 2023, ISSN 2076-3921
Publisher: MDPI
DOI: 10.3390/antiox12020371

The Hepatokine RBP4 Links Metabolic Diseases to Articular Inflammation

Author(s): Andrés Pazos-Pérez, María Piñeiro-Ramil, Eloi Franco-Trepat, Ana Alonso-Pérez, María Guillán-Fresco, Antía Crespo-Golmar, Miriam López-Fagúndez, Javier Conde Aranda, Susana Belen Bravo, Alberto Jorge-Mora and Rodolfo Gómez
Published in: Antioxidants, 2024, ISSN 2076-3921
Publisher: MDPI
DOI: 10.3390/antiox13010124

Atherosclerosis

Author(s): J. Parantainen, G. Barreto, T.E. Strandberg, N. Mars, K. Nurmi, K.K. Eklund
Published in: Atherosclerosis, Issue 405, 2025, ISSN 1879-1484
Publisher: Elsevier BV
DOI: 10.1016/J.ATHEROSCLEROSIS.2025.119220

Sensor-integrated gut-on-a-chip for monitoring senescence-mediated changes in the intestinal barrier

Author(s): Konstanze Brandauer; Alexandra Lorenz; Silvia Schobesberger; Patrick Schuller; Martin Frauenlob; Sarah Spitz; Peter Ertl
Published in: Lab on a Chip, 2025, ISSN 1473-0189
Publisher: Royal Society of Chemistry
DOI: 10.1039/D4LC00896K

Beyond Seasoning—The Role of Herbs and Spices in Rheumatic Diseases

Author(s): Charneca, Sofia; Hernando, Ana; Costa-Reis, Patricia; Guerreiro, Catarina Sousa
Published in: Nutrients, 2023, ISSN 2072-6643
Publisher: MDPI
DOI: 10.3390/nu15122812

Formononetin, a Beer Polyphenol with Catabolic Effects on Chondrocytes

Author(s): María Guillán-Fresco; Eloi Franco-Trepat; Ana Alonso-Pérez; Alberto Jorge-Mora; Verónica López-López; Andrés Pazos-Pérez; María Piñeiro-Ramil; Rodolfo Gómez
Published in: Nutrients, 2023, ISSN 2072-6643
Publisher: MDPI
DOI: 10.3390/nu15132959

The collagenase-induced osteoarthritis (CIOA) model: Where mechanical damage meets inflammation

Author(s): Patrick Weber; Kajetana Bevc; David Fercher; Sami Kauppinen; Shipin Zhang; Maryam Asadikorayem; Lucia Baixauli Marin; Tanqi Zhang; Tuomas Frondelius; Gian Salzmann; Valentino Bruhin; Jakob Hax; Gonçalo Barreto; Mikko A.J. Finnilä; Marcy Zenobi-Wong
Published in: Osteoarthritis and Cartilage Open, 2024, ISSN 2665-9131
Publisher: Elsevier
DOI: 10.3929/ETHZ-B-000705561

Nutrition Journal

Author(s): Charneca, Sofia; Hernando, Ana; Almada-Correia, Inês; Polido Pereira, Joaquim; Vieira, Adriana; Sousa, Joana; Almeida, Ana S.; Motta, Carla Motta; Barreto, Gonçalo; Eklund, Kari K.; Alnso‑Pérez, Ana; Gómez, Rodolfo; Cicc, Francesco; Mauro, Daniele; Pinho, Salomé S.; Fonseca, João Eurico; Costa Reis, Patricia; Guerreiro, Catarina Sousa
Published in: Nutrition Journal, 2025, ISSN 1475-2891
Publisher: BMC
DOI: 10.1186/S12937-025-01089-6

Evaluating the role of lipopolysaccharides in the joint: fibronectin as a novel protective mechanism

Author(s): Bevc, Kajetana; Zhang, Shipin; Pazos-Perez, Andres; Alonso-Perez, Ana; Fercher, David; Kauppinen, Sami; Frondelius, Tuomas; Bruhin, Valentino; Salzmann, Gian; Rauer, Thomas; Pape, Hans-Christoph; Finnilä, Mikko Arttu Jalmari; Ospelt, Caroline; Gomez, Rodolfo; Eklund, Kari K; Wong, Marcy Zenobi; Barreto, Goncalo
Published in: RMD Open, 2025, ISSN 2056-5933
Publisher: BMJ
DOI: 10.3929/ETHZ-B-000746816