Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH (non-alcoholic steatohepatitis) transition to inform early prevention and treatment strategies

Project Information

halt-RONIN

Grant agreement ID: 101095679

DOI

10.3030/101095679

EC signature date 22 November 2022

Start date 1 December 2022

End date 30 November 2026

Funded under

• Health

Total cost

€ 6 721 927,53

EU contribution

€ 6 721 927,28

Coordinated by

UNIVERSIDAD COMPLUTENSE DE MADRID
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Data Management Plan (DMP)

A data management plan following the guidelines of the FAIR and GDPR principles using the Horizon Europe template and rules

Dissemination, communication and exploitation strategy

Development of a common Dissemination and Exploitation plan in the Project, which will be used by all the partners involved in Halt-RONIN Project.

Websites, patent fillings, videos etc. (1)

Project Website Launch

Since the beginning of the project a data management and protection plan will be established.

Publications

Peer reviewed articles (40)

Endoscopic ultrasound portal pressure gradient: possible discrepancies in metabolic dysfunction-associated steatotic liver disease-related portal pressure measurements

Author(s): Jesús Rivera-Esteban, Daniel de la Iglesia Garcia, Belen Agudo-Castillo, Jose Luis Calleja, Elba Llop
Published in: Endoscopy, Issue 57, 2025, ISSN 0013-726X
Publisher: Georg Thieme Verlag KG
DOI: 10.1055/A-2423-4738

Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signalling.

Author(s): Rodrigues JS, Pereira AF, Camões SP, Serras AS, Morais VA, Ruas JL, Miranda JP.
Published in: Front. Endocrinol, 2022, ISSN 1664-2392
Publisher: Frontiers Media S.A.
DOI: 10.3389/FENDO.2022.1043543

FTO/m6A/GPNMB axis: a novel promising target for hepatocellular carcinoma (HCC) treatment?

Author(s): Bernd Heinrich, Francisco Javier Cubero
Published in: Gut, Issue 74, 2024, ISSN 0017-5749
Publisher: BMJ
DOI: 10.1136/gutjnl-2024-332934

Stard1 promotes cholestatic liver injury and disease progression by sensitizing to bile acid hepatotoxicity

Author(s): Laura Conde de la Rosa, Laura Fàbrega, Sandra Torres, Susana Nuñez, Vicent Ribas, Paula Segalés, Ricardo Espinosa-Escudero, Estel Solsona, María Jesús Monte, Alvaro Diaz-Gonzalez, José J. G. Marin, Carmen García-Ruiz, Jose C. Fernandez-Checa
Published in: Hepatology, 2025, ISSN 0270-9139
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/HEP.0000000000001184

Drug-induced Liver Injury in Latin America: 10-year Experience of the Latin American DILI (LATINDILI) Network

Author(s): Fernando Bessone, Nelia Hernandez, Inmaculada Medina-Caliz, Miren García-Cortés, María I. Schinoni, Manuel Mendizabal, Daniela Chiodi, Vinicius Nunes, Ezequiel Ridruejo, Ximena Pazos, Genario Santos, Eduardo Fassio, Raymundo Parana, Virginia Reggiardo, Hugo Tanno, Adriana Sanchez, Federico Tanno, Pedro Montes, Martin Tagle, Marco Arrese, Javier Brahm, Marcos Girala, M. Isabel Lizarzabal, Enrique Carrera, Alina Zerega, Carla Bianchi, Laura Reyes, Daina Arnedillo, Antonella Cordone, Gisela Gualano, Fernanda Jaureguizahar, Gabriel Rifrani, Mercedes Robles-Díaz, Aida Ortega-Alonso, José M. Pinazo-Bandera, Camilla Stephens, Judith Sanabria-Cabrera, Elvira Bonilla-Toyos, Hao Niu, Ismael Alvarez-Alvarez, M. Isabel Lucena, Raul J. Andrade
Published in: Clinical Gastroenterology and Hepatology, Issue 23, 2024, ISSN 1542-3565
Publisher: Elsevier BV
DOI: 10.1016/j.cgh.2024.06.030

Mitochondrial cholesterol: Metabolism and impact on redox biology and disease

Author(s): Leire Goicoechea,a,b,c Laura Conde de la Rosa,a,b,c Sandra Torres,a,b,c Carmen García-Ruiz,a,b,c,d,∗∗ and José C. Fernández-Checaa,b,c,d,∗
Published in: Redox Biology, 2023, ISSN 2213-2317
Publisher: Elsevier
DOI: 10.1016/J.REDOX.2023.102643

A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d.

Author(s): Domènech Omella J, Cortesi EE, Verbinnen I, Remmerie M, Wu H, Cubero FJ, Roskams T, Janssens V
Published in: Cancers (Basel), 2023, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/CANCERS15164193

Nature Communications

Author(s): Raquel A. Martínez García de la Torre; Julia Vallverdú; Zhenqing Xu; Silvia Ariño; Raquel Ferrer-Lorente; Laura Zanatto; Maria Mercado-Gómez; Beatriz Aguilar-Bravo; Paloma Ruiz-Blázquez; Maria Fernandez- Fernandez; Artur Navarro-Gascon; Albert Blasco-Roset; Paula Sànchez-Fernàndez-de-Landa; Joan Pera; Damia Romero-Moya; Paula Ayuso Garcia; Celia Martínez Sánchez; Laura Sererols Viñas; Paula Cantallops Vilà; Carmen I. Cárcamo Giráldez; Andrew McQuillin; Marsha Y. Morgan; Daniel Moya-Rull; Núria Montserrat; Delphine Eberlé; Bart Staels; Bénédicte Antoine; Mikel Azkargorta; Juan-José Lozano; Maria L. Martínez-Chantar; Alessandra Giorgetti; Félix Elortza; Anna Planavila; Marta Varela-Rey; Ashwin Woodhoo; Antonio Zorzano; Isabel Graupera; Anna Moles; Mar Coll; Silvia Affo; Pau Sancho-Bru
Published in: Nature Communications, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/S41467-025-56024-4

Cathepsin D is essential for the degradomic shift of macrophages required to resolve liver fibrosis

Author(s): Paloma Ruiz-Blázquez, María Fernández-Fernández, Valeria Pistorio, Celia Martinez-Sanchez, Michele Costanzo, Paula Iruzubieta, Ekaterina Zhuravleva, Júlia Cacho-Pujol, Silvia Ariño, Alejandro Del Castillo-Cruz, Susana Núñez, Jesper B. Andersen, Margherita Ruoppolo, Javier Crespo, Carmen García-Ruiz, Luigi Michele Pavone, Thomas Reinheckel, Pau Sancho-Bru, Mar Coll, José C. Fernández-Checa, Anna Moles
Published in: Molecular Metabolism, Issue 87, 2024, ISSN 2212-8778
Publisher: Elsevier BV
DOI: 10.1016/j.molmet.2024.101989

Cirrhosis‐downregulated <scp>LSECtin</scp> can be retrieved by cytokines, shifts the <scp>TLR</scp>‐induced <scp>LSECs</scp> secretome and correlates with the hepatic Th response

Author(s): Sebastián Martínez‐López; Enrique Ángel‐Gomis; Isabel Gómez‐Hurtado; Anabel Fernández‐Iglesias; Javier Morante; Jordi Gracia‐Sancho; Paula Boix; Francisco J. Cubero; Pedro Zapater; Esther Caparrós; Rubén Francés
Published in: Liver International, 2024, ISSN 1478-3231
Publisher: Wiley
DOI: 10.1111/LIV.15836

Control Compounds for Preclinical Drug-Induced Liver Injury Assessment: Consensus-driven systematic review by the ProEuroDILI Network

Author(s): Segovia-Zafra A, Villanueva-Paz M, Serras AS, Matilla-Cabello G, Bodoque-García A, Di Zeo-Sánchez D, Niu H, Álvarez-Álvarez I, Sanz-Villanueva L, Godec S, Milisav I, Bagnaninchi I, Andrade RJ, Lucena MI, Fernández-Checa JC, Cubero FJ, Miranda JP, Nelson L
Published in: Journal of Hepatology, 2024, ISSN 0168-8278
Publisher: Elsevier
DOI: 10.1016/J.JHEP.2024.04.026

Nature Medicine

Author(s): Timothy J. Kendall; Maria Jimenez-Ramos; Frances Turner; Prakash Ramachandran; Jessica Minnier; Michael D. McColgan; Masood Alam; Harriet Ellis; Donald R. Dunbar; Gabriele Kohnen; Prakash Konanahalli; Karin A. Oien; Lucia Bandiera; Filippo Menolascina; Anna Juncker-Jensen; Douglas Alexander; Charlie Mayor; Indra Neil Guha; Jonathan A. Fallowfield
Published in: Nature Medicine, 2023, ISSN 1078-8956
Publisher: Nature Portfolio
DOI: 10.1038/S41591-023-02602-2

Biochimica et Biophysica Acta - Molecular Basis of Disease

Author(s): Guillermo, Bordanaba-Florit; Félix, Royo; Oihane E, Albóniga; Aled, Clayton; Juan Manuel, Falcón-Pérez; Jason, Webber
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2024, ISSN 0925-4439
Publisher: Elsevier
DOI: 10.1016/J.BBADIS.2024.167229

Reproducibility of extracellular vesicle research

Author(s): Rossella Crescitelli; Juan Falcon‐Perez; An Hendrix; Metka Lenassi; Le Thi Nguyet Minh; Takahiro Ochiya; Nicole Noren Hooten; Ursula Sandau; Clotilde Théry; Rienk Nieuwland
Published in: Journal of Extracellular Vesicles, 2025, ISSN 2001-3078
Publisher: Wiley
DOI: 10.1002/JEV2.70036

Curcumin encapsulated in milk small extracellular vesicles as a nanotherapeutic alternative in experimental chronic liver disease

Author(s): Virginia Albaladejo-García, Laura Morán, Ana Santos-Coquillat, María I. González, Hui Ye, Elena Vázquez Ogando, Javier Vaquero, Francisco Javier Cubero, Manuel Desco, Beatriz Salinas
Published in: Biomedicine & Pharmacotherapy, 2024, ISSN 1950-6007
Publisher: Elsevier
DOI: 10.1016/J.BIOPHA.2024.116381

Novel Emerging Mechanisms in Acetaminophen (<scp>APAP</scp>) Hepatotoxicity

Author(s): Alejandro Hionides‐Gutierrez, Naroa Goikoetxea‐Usandizaga, Carlos Sanz‐García, María L. Martínez‐Chantar, Francisco Javier Cubero
Published in: Liver International, 2024, ISSN 1478-3223
Publisher: Wiley
DOI: 10.1111/liv.16167

Cholesterol’s new tricks propel MASH-HCC: impact in immunotherapy

Author(s): Carmen Garcia-Ruiz; Sandra Torres; Jose C Fernandez-Checa
Published in: Gut, 2024, ISSN 1468-3288
Publisher: BMJ
DOI: 10.1136/GUTJNL-2024-332766

Identification of PRMT5 as a therapeutic target in cholangiocarcinoma

Author(s): Jasmin Elurbide, Leticia Colyn, Maria U Latasa, Iker Uriarte, Stefano Mariani, Amaya Lopez-Pascual, Emiliana Valbuena, Borja Castello-Uribe, Robert Arnes-Benito, Elena Adan-Villaescusa, Luz A Martinez-Perez, Mikel Azkargorta, Felix Elortza, Hanghang Wu, Marcin Krawczyk, Kai Markus Schneider, Bruno Sangro, Luca Aldrighetti, Francesca Ratti, Andrea Casadei Gardini, Jose J G Marin, Irene Amat, Jesus M Urman, Maria Arechederra, Maria Luz Martinez-Chantar, Christian Trautwein, Meritxell Huch, Francisco Javier Cubero, Carmen Berasain, Maite G Fernandez-Barrena, Matias A Avila
Published in: Gut, Issue 74, 2024, ISSN 0017-5749
Publisher: BMJ
DOI: 10.1136/gutjnl-2024-332998

Dietary and genetic disruption of hepatic methionine metabolism induce acid sphingomyelinase to promote steatohepatitis

Author(s): Cristina Alarcón-Vila 1, Naroa Insausti-Urkia 1, Sandra Torres 1, Paula Segalés-Rovira 1, Laura Conde de la Rosa 1, Susana Nuñez 1, Raquel Fucho 1, Jose C Fernández-Checa 2, Carmen García-Ruiz 3
Published in: Redox Biology, 2022, ISSN 2213-2317
Publisher: Elsevier BV
DOI: 10.1016/J.REDOX.2022.102596

Tumor progression locus 2 (TPL2): A Cot-plicated progression from inflammation to chronic liver disease

Author(s): Alejandro H Gutierrez 1, Marina S Mazariegos 1, Susana Alemany 2, Yulia A Nevzorova 3, Francisco Javier Cubero 3, Carlos Sanz-García 4
Published in: Molecular Basis of disease, 2023, ISSN 0925-4439
Publisher: Elsevier
DOI: 10.1016/J.BBADIS.2023.166660

Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis

Author(s): Arantza Lamas-Paz, Alejandro Hionides-Gutiérrez, Feifei Guo, Gonzalo Jorquera, Laura Morán-Blanco, Raquel Benedé-Ubieto, Mariana Mesquita, Olga Estévez-Vázquez, Kang Zheng, Marina Mazariegos, Elena Vázquez-Ogando, Elena Blázquez-López, Iris Asensio, Beste Mutlu, Beatriz Gomez-Santos, María Isabel Peligros, Javier Vaquero, Rafael Bañares, Teresa C. Delgado, María Luz Martínez-Chantar, Eduardo Martínez-Naves, Carlos Sanz-García, Mohamed Ramadan Mohamed, Sofía Tesolato, Pilar Iniesta, Rocío Gallego-Durán, Douglas Maya-Miles, Javier Ampuero, Manuel Romero-Gómez, Ana Martínez-Alcocer, David Sanfeliu-Redondo, Anabel Fernández-Iglesias, Jordi Gracia-Sancho, Mar Coll, Isabel Graupera, Pere Ginès, Andrea Ciudin, Jesús Rivera-Esteban, Juan M. Pericàs, Matías A. Ávila, Maria Dolores Frutos, Carlos Manuel Martínez-Cáceres, Bruno Ramos-Molina, Patricia Aspichueta, Pere Puigserver, Yulia A. Nevzorova, Francisco Javier Cubero
Published in: JHEP Reports, Issue 7, 2025, ISSN 2589-5559
Publisher: Elsevier BV
DOI: 10.1016/j.jhepr.2024.101230

Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet

Author(s): M.I. Lucena, M. Villanueva-Paz, I. Alvarez-Alvarez, G.P. Aithal, E.S. Björnsson, G. Cakan-Akdogan, F.J. Cubero, F. Esteves , J.M. Falcon-Perez , B. Fromenty, C. Garcia-Ruiz, J.I. Grove, O. Konu, M. Kranendonk, G.A. Kullak-Ublick, J.P. Miranda, et al.
Published in: Pharmacological Research, 2023, ISSN 1043-6618
Publisher: Elsevier
DOI: 10.1016/J.PHRS.2023.107046

The Cantabria Cohort, a protocol for a population-based cohort in northern Spain

Author(s): Marta Alonso-Peña, Trinidad Dierssen, Maria José Marin, Jessica Alonso-Molero, Inés Gómez-Acebo, Inés Santiuste, Jeffrey V. Lazarus, Pascual Sanchez-Juan, Galo Peralta, Javier Crespo, Marcos Lopez-Hoyos & Cantabria Cohort Collaborators
Published in: BMC Public Health, 2023, ISSN 1471-2458
Publisher: BioMed Central
DOI: 10.1186/S12889-023-17318-8

Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress

Author(s): Beatriz Martín-Adrados; Stefanie K. Wculek; Sergio Fernández-Bravo; Raúl Torres-Ruiz; Ana Valle-Noguera; Maria José Gomez-Sánchez; José Carlos Hernández-Walias; Frederico Moraes Ferreira; Ana María Corraliza; David Sancho; Vanesa Esteban; Sandra Rodriguez-Perales; Aránzazu Cruz-Adalia; Helder I. Nakaya; Azucena Salas; David Bernardo; Yolanda Campos-Martín; Elena Martínez-Zamorano; Diego Muñoz-López; Manuel Gómez del Moral; Francisco Javier Cubero; Richard S. Blumberg; Eduardo Martínez-Naves
Published in: Frontiers in Inmmunology, 2023, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2023.1185517

Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis

Author(s): Zheng K, Hao F, Medrano-Garcia S, Chen C, Guo F, Morán-Blanco L, Rodríguez-Perales S, Torres-Ruiz R, Peligros MI, Vaquero J, Bañares R, Gómez Del Moral M, Regueiro JR, Martínez-Naves E, Mohamed MR, Gallego-Durán R, Maya D, Ampuero J, Romero-Gómez M, Gilbe
Published in: Cell Death and Disease, 2023, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/S41419-023-06029-Y

Gastroenterologia y Hepatologia

Author(s): Alvarado-Tapias, Edilmar; Maya-Miles, Douglas; Albillos, Agustin; Aller, Rocio; Ampuero, Javier; Andrade, Raul J.; Arechederra, Maria; Aspichueta, Patricia; Banales, Jesus M.; Blas-García, Ana; Caparros, Esther; Cardoso Delgado, Teresa; Carrillo-Vico, Antonio; Claria, Joan; Cubero, Francisco Javier; Díaz-Ruiz, Alberto; Fernández-Barrena, Maite G.; Fernández-Iglesias, Anabel; Fernández-Veledo, Sonia; Francés, Ruben; Gallego-Durán, Rocío; Gracia-Sancho, Jordi; Irimia, Manuel; Lens, Sabela; Martínez-Chantar, María Luz; Mínguez, Beatriz; Muñoz-Hernández, Rocío; Nogueiras, Rubén; Ramos-Molina, Bruno; Riveiro-Barciela, Mar; Rodríguez-Perálvarez, Manuel L.; Romero-Gómez, Manuel; Sabio, Guadalupe; Sancho-Bru, Pau; Ventura-Cots, Meritxell; Vidal, Silvia; Gahete, Manuel D.
Published in: Gastroenterología y Hepatología (English Edition), 2024, ISSN 0210-5705
Publisher: Ediciones Doyma S.A.
DOI: 10.1016/j.gastrohep.2024.502207

Zonal expression of StARD1 and oxidative stress in alcoholic-related liver disease

Author(s): Raquel Fucho 1, Estel Solsona-Vilarrasa 1, Sandra Torres 1, Susana Nuñez 1, Naroa Insausti-Urkia 1, Albert Edo 1, Maria Calvo 2, Anna Bosch 2, Gemma Martin 2, Carlos Enrich 3, Carmen García-Ruiz 4, Jose C Fernandez-Checa
Published in: J Lipid Res, 2023, ISSN 0022-2275
Publisher: Elsevier
DOI: 10.1016/J.JLR.2023.100413

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol

Author(s): Arantza Lamas-Paz, Mariana Mesquita, Marcos Garcia-Lacarte, Olga Estévez-Vázquez, Raquel Benedé-Ubieto, Alejandro H. Gutierrez, Hanghang Wu, Hector Leal Lasalle, Javier Vaquero, Rafael Bañares, Eduardo Martínez-Naves, Sergio Roa, Yulia A. Nevzorova, Gonzalo Jorquera, Francisco Javier Cubero
Published in: Frontiers in Nutrition, Issue 11, 2024, ISSN 2296-861X
Publisher: Frontiers Media SA
DOI: 10.3389/fnut.2024.1393014

ECM1: a novel matricellular protein with promising antifibrotic potential

Author(s): Isabel Fabregat, Francisco Javier Cubero
Published in: Gut, 2024, ISSN 0017-5749
Publisher: BMJ
DOI: 10.1136/gutjnl-2024-333455

Palmitoylcarnitine impairs immunity in decompensated cirrhosis

Author(s): Ingrid Wei Zhang; María Belén Sánchez-Rodríguez; Cristina López-Vicario; Mireia Casulleras; Marta Duran-Güell; Roger Flores-Costa; Ferran Aguilar; Michael Rothe; Paula Segalés; Carmen García-Ruiz; José C. Fernández-Checa; Jonel Trebicka; Vicente Arroyo; Joan Clària
Published in: JHEP Reports, 2024, ISSN 2589-5559
Publisher: Elsevier
DOI: 10.1016/J.JHEPR.2024.101187

S-Adenosyl-l-methionine restores brain mitochondrial membrane fluidity and GSH content improving Niemann-Pick type C disease

Author(s): Leire Goicoechea 1, Sandra Torres 1, Laura Fàbrega 1, Mónica Barrios 1, Susana Núñez 2, Josefina Casas 3, Gemma Fabrias 3, Carmen García-Ruiz 4, José C Fernández-Checa 5
Published in: Redox Biology, 2024, ISSN 2213-2317
Publisher: Elsevier
DOI: 10.1016/J.REDOX.2024.103150

Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism

Author(s): Esteves, F.; Almeida, C.M.M.; Silva, S.; Saldanha, I.; Urban, P.; Rueff, J.; Pompon, D.; Truan, G.; Kranendonk, M.
Published in: Biomolecules, 2023, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom13071083

Breaking the barriers: the role of gut homeostasis in Metabolic-Associated Steatotic Liver Disease (MASLD)

Author(s): Raquel Benedé, Francisco Javier Cubero, Yulia A. Nevzorova
Published in: Gut microbes, Issue 1, 2331460, 2024, ISSN 1949-0984
Publisher: Taylor & Francis
DOI: 10.1080/19490976.2024.2331460

Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification

Author(s): H. Niu, P. Solis-Muñoz, M. García-Cortés, J. Sanabria-Cabrera, M. Robles-Diaz, R. Romero-Flores, E. Bonilla-Toyos, A. Ortega-Alonso, J. M. Pinazo-Bandera, M. R. Cabello, F. Bessone, N. Hernandez, M. I. Lucena, R. J Andrade, I. Medina-Caliz, I. Álvarez-Álv
Published in: Pharmacological Research, Issue 199, 2024, ISSN 1043-6618
Publisher: Academic Press
DOI: 10.1016/j.phrs.2023.107030

Toxicology Letters

Author(s): Kuhn, Joel; McDonald, Alison; Mongoin, Cyril; Anderson, Graham; Lafeuillade, Guillemette; Mitchell, Stephen; Elfick, Alistair P.D.; Bagnaninchi, Pierre O.; Yiu, Humphrey H.P.; Nelson, Leonard J.
Published in: Toxicology Letters, 2024, ISSN 0378-4274
Publisher: Elsevier
DOI: 10.1016/J.TOXLET.2024.02.010

CAP-RNAseq: an integrated pipeline for functional annotation and prioritization of co-expression clusters

Author(s): Merve Vural-Ozdeniz, Kubra Calisir, Rana Acar, Aysenur Yavuz, Mustafa M Ozgur, Ertugrul Dalgıc, Ozlen Konu
Published in: Briefings in Bioinformatics, 2024, ISSN 1477-4054
Publisher: Oxford Journals
DOI: 10.1093/bib/bbad536

Randomization based evaluation of distinct topological and cancer expression characteristics of mutually acting gene pairs

Author(s): Ertuğrul Dalgıç, Muazzez Çelebi-Çınar, Merve Vural-Özdeniz, Özlen Konu
Published in: Integrative Biology, Issue 17, 2025, ISSN 1757-9708
Publisher: Oxford University Press (OUP)
DOI: 10.1093/INTBIO/ZYAF005

Polygenic risk score in cirrhosis: Does the etiology matter?

Author(s): Alonso-Peña, Marta; Arias Loste, Maria Teresa; Cabezas, Joaquin; Iruzubieta, Paula; Crespo, Javier
Published in: Hepatology Communications, 2025, ISSN 2471-254x
Publisher: Wolters Kluwer Health
DOI: 10.1097/HC9.0000000000000541

Inhibition of ALK3-mediated signalling pathway protects against acetaminophen-induced liver injury

Author(s): Patricia Marañón 1, Esther Rey 2, Stephania C Isaza 2, Hanghang Wu 3, Patricia Rada 4, Carmen Choya-Foces 2, Antonio Martínez-Ruiz 5, María Ángeles Martín 6, Sonia Ramos 6, Carmelo García-Monzón 2, Francisco Javier Cubero 7, Ángela M Valverde 4, Águeda Go
Published in: Redox Biology, 2024, ISSN 2213-2317
Publisher: Elsevier
DOI: 10.1016/J.REDOX.2024.103088

Seladelpar: New hope for patients with primary biliary cholangitis

Author(s): Nevzorova, Yulia A.; Cubero, Francisco Javier
Published in: Med, 2024, ISSN 0121-5256
Publisher: Cell Press
DOI: 10.1016/j.medj.2024.03.019

Other (2)

Redox Biology

Author(s): Rojo, Ana I.; Buttari, Brigitta; Cadenas, Susana; Carlos, Ana Rita; Cuadrado, Antonio; Falcão, Ana Sofia; López, Manuela G.; Georgiev, Milen I.; Grochot-Przeczek, Anna; Gumeni, Sentiljana; Jimenez-Villegas, José; Horbanczuk, Jarosław Olav; Konu, Ozlen; Lastres-Becker, Isabel; Levonen, Anna-Liisa; Maksimova, Viktorija; Michaeloudes, Charalambos; Mihaylova, Liliya V.; Mickael, Michel Edwar; Milisav, Irina; Miova, Biljana; Rada, Patricia; Santos, Marlene; Seabra, Miguel C.; Strac, Dubravka Svob; Tenreiro, Sandra; Trougakos, Ioannis P.; Dinkova-Kostova, Albena T.
Published in: Redox Biology, 2025, ISSN 2213-2317
Publisher: Elsevier
DOI: 10.1016/J.REDOX.2024.103464

Liver International

Author(s): Hionides‐Gutierrez, Alejandro; Goikoetxea‐Usandizaga, Naroa; Sanz‐García, Carlos; Martínez‐Chantar, María L.; Cubero, Francisco Javier
Published in: Liver International, 2024, ISSN 1478-3223
Publisher: Wiley
DOI: 10.1111/LIV.16167

Conference proceedings (1)

Proceedings of the 5th Meeting of Translational Hepatology, organized by the Spanish Association for the Study of the Liver (AEEH)

Author(s): Edilmar Alvarado-Tapias, Douglas Maya-Miles, Agustin Albillos, Rocio Aller, Javier Ampuero, Raul J. Andrade, Maria Arechederra, Patricia Aspichueta, Jesus M. Banales, Ana Blas-García, Esther Caparros, Teresa Cardoso Delgado, Antonio Carrillo-Vico, Joan Claria, Francisco Javier Cubero, Alberto Díaz-Ruiz, Maite G. Fernández-Barrena, Anabel Fernández-Iglesias, Sonia Fernández-Veledo, Ruben Francés, Rocío Gallego-Durán, Jordi Gracia-Sancho, Manuel Irimia, Sabela Lens, María Luz Martínez-Chantar, Beatriz Mínguez, Rocío Muñoz-Hernández, Rubén Nogueiras, Bruno Ramos-Molina, Mar Riveiro-Barciela, Manuel L. Rodríguez-Perálvarez, Manuel Romero-Gómez, Guadalupe Sabio, Pau Sancho-Bru, Meritxell Ventura-Cots, Silvia Vidal, Manuel D. Gahete
Published in: Gastroenterología y Hepatología (English Edition), Issue 47, 2024, ISSN 2444-3824
Publisher: Elsevier BV
DOI: 10.1016/j.gastre.2024.502207