Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH (non-alcoholic steatohepatitis) transition to inform early prevention and treatment strategies

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Data Management Plan (DMP) update-2

The DMP will be updated to include any changes or adaptations done from the initial research plan.

Data Management Plan (DMP)

A data management plan following the guidelines of the FAIR and GDPR principles using the Horizon Europe template and rules

Dissemination, communication and exploitation strategy

Development of a common Dissemination and Exploitation plan in the Project, which will be used by all the partners involved in Halt-RONIN Project.

Data Management Plan (DMP) update-1

The DMP will be updated to include any changes or adaptations done from the initial research plan.

Publikacje

Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity

Autorzy: Barata, I.S.; Rueff, J.; Kranendonk, M.; Esteves, F
Opublikowane w: J Xenobiotic, ISSN 2039-4713
Wydawca: MDPI
DOI: 10.3390/JOX14020034

LSECtin attenuates hepatic Th17 expansion in a murine model of cirrhosis and signals through the LAG-3 receptor

Autorzy: Sebastián Martínez-López, Oriol Juanola, Isabel Gómez-Hurtado, Enrique Ángel-Gomis, Paula Boix, Anabel Fernández-Iglesias, Alex Gallardo-Cruz, Francisco Javier Cubero, Jordi Gracia-Sancho, Amaya Puig-Kröger, Esther Caparrós, Rubén Francés
Opublikowane w: JHEP Reports, Numer 7, 2025, ISSN 2589-5559
Wydawca: Elsevier BV
DOI: 10.1016/J.JHEPR.2025.101482

Rechallenge in idiosyncratic drug-induced liver injury: An analysis of cases in two large prospective registries according to existing definitions

Autorzy: J.M. Pinazo-Bandera, H. Niu, I. Alvarez-Alvarez, I. Medina-Cáliz, E. Del Campo-Herrera, A. Ortega-Alonso, M. Robles-Díaz, N. Hernández, R. Paraná, V. Nunes, M. Girala, F. Bessone, M.I. Lucena, R.J. Andrade, M. García Cortés
Opublikowane w: Pharmacological Research, Numer 203, 2024, ISSN 1043-6618
Wydawca: Elsevier BV
DOI: 10.1016/J.PHRS.2024.107183

Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signalling.

Autorzy: Rodrigues JS, Pereira AF, Camões SP, Serras AS, Morais VA, Ruas JL, Miranda JP.
Opublikowane w: Front. Endocrinol, 2022, ISSN 1664-2392
Wydawca: Frontiers Media S.A.
DOI: 10.3389/FENDO.2022.1043543

JNKs protect from cholestatic liver disease progression by modulating Apelin signalling

Autorzy: Mohamed MR, Haybaeck J, Wu H, Su H, Bartneck M, Lin C, Boekschoten MV, Boor P, Goeppert B, Rupp C, Strnad P, Davis RJ, Cubero FJ, Trautwein C
Opublikowane w: JHEP Rep., ISSN 2589-5559
Wydawca: Elsevier BV
DOI: 10.1016/J.JHEPR.2023.100854

Mitochondrial cholesterol: Metabolism and impact on redox biology and disease

Autorzy: Leire Goicoechea,a,b,c Laura Conde de la Rosa,a,b,c Sandra Torres,a,b,c Carmen García-Ruiz,a,b,c,d,∗∗ and José C. Fernández-Checaa,b,c,d,∗
Opublikowane w: Redox Biology, 2023, ISSN 2213-2317
Wydawca: Elsevier
DOI: 10.1016/J.REDOX.2023.102643

Fatty acid-mediated induction of CYP2E1 activity in HepaRG cells is not systematically associated with exacerbated acetaminophen cytotoxicity

Autorzy: Clémence Penhoat, Julie Massart, Gregory Pinon, Daniel Catheline, Vincent Rioux, Bernard Fromenty, Karima Begriche
Opublikowane w: bioRxiv, ISSN 2692-8205
Wydawca: biorxiv
DOI: 10.1101/2024.11.01.621521V1

Enhancing the Maturity and Diclofenac Metabolism Ability of Mesenchymal Stem Cell‐Derived Human Hepatocytes In Vitro Using Microfluidics Technology

Autorzy: Joana Saraiva Rodrigues, Sofia Relvas, Pedro Monteiro Condelipes, Bárbara Silva, Raquel Bozzo, Paula Guedes de Pinho, Virginia Chu, Fernando Remião, João Pedro Conde, Joana Paiva Miranda
Opublikowane w: Biotechnology Journal, Numer 20, 2025, ISSN 1860-6768
Wydawca: Wiley
DOI: 10.1002/BIOT.70037

Patient-derived liver organoids recapitulate liver epithelial heterogeneity and enable precision modeling of alcohol-related liver disease

Autorzy: Silvia Ariño, Raquel Ferrer-Lorente, Guillermo Serrano, Laura Zanatto, Raquel A. Martínez-García de la Torre, Jordi Gratacós-Ginès, Ana Belén Rubio, Martina Pérez, Carlos Mateos-Sánchez, Beatriz Aguilar-Bravo, Stephen Atkinson, Zhengqing Xu, Paula Cantallops-Vilà, Laura Sererols-Viñas, Paloma Ruiz-Blázquez, Aina Rill, Yiliam Fundora, Juan José Lozano, Mar Coll, Idoia Ochoa, Silvia Affo, Anna Moles, Elisabetta Mereu, Ramón Bataller, Elisa Pose, Pau Sancho-Bru
Opublikowane w: Journal of Hepatology, Numer 84, 2026, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/J.JHEP.2025.07.014

A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d.

Autorzy: Domènech Omella J, Cortesi EE, Verbinnen I, Remmerie M, Wu H, Cubero FJ, Roskams T, Janssens V
Opublikowane w: Cancers (Basel), 2023, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/CANCERS15164193

Metabolic dysfunction–associated steatotic liver disease alters brain function and behavior: Insights from liver-targeted siRNA therapy

Autorzy: Teresa Cardoso Delgado; Celia Martín-Cuevas; Ana C. Sánchez Hidalgo; Antonio Gil Gómez; Claudia M. Rejano Gordillo; Jon Landa; Rocío Gallego Durán; Naroa Goikoetxea-Usandizaga; Irene González-Recio; Clàudia Gil-Pitarch; L. Estefanía Zapata-Pavas; Jon Ander Barrenechea-Barrenechea; Carolina Conter; Luis Alfonso Martínez-Cruz; Víctor D. Ramos Herrero; Rubén Nogueiras; Mikel Azkargorta; Felix Elortza; Verónica Moncho-Amor; Javier Crespo; Ander Matheu; Manuel Romero Gómez; Benedicto Crespo-Facorro; María Luz Martínez-Chantar
Opublikowane w: Science Advances, 2025, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADY9758

Three-Dimensional Hepatocyte Spheroids: Model for Assessing Chemotherapy in Hepatocellular Carcinoma

Autorzy: Felix Royo; Clara Garcia-Vallicrosa, Maria Azparren-Angulo, Guillermo Bordanaba-Florit, Silvia Lopez-Sarrio, Juan Manuel Falcon-Perez
Opublikowane w: Biomedicines, ISSN 2227-9059
Wydawca: MDPI
DOI: 10.3390/BIOMEDICINES12061200

Cirrhosis‐downregulated <scp>LSECtin</scp> can be retrieved by cytokines, shifts the <scp>TLR</scp>‐induced <scp>LSECs</scp> secretome and correlates with the hepatic Th response

Autorzy: Sebastián Martínez‐López; Enrique Ángel‐Gomis; Isabel Gómez‐Hurtado; Anabel Fernández‐Iglesias; Javier Morante; Jordi Gracia‐Sancho; Paula Boix; Francisco J. Cubero; Pedro Zapater; Esther Caparrós; Rubén Francés
Opublikowane w: Liver International, 2024, ISSN 1478-3231
Wydawca: Wiley
DOI: 10.1111/LIV.15836

Obesity under the moonlight of c-MYC

Autorzy: Yulia A. Nevzorova and Francisco Javier Cubero
Opublikowane w: Frontiers in cells and developmental biology, ISSN 2296-634X
Wydawca: Frontiers
DOI: 10.3389/FCELL.2023.1293218

Biochimica et Biophysica Acta - Molecular Basis of Disease

Autorzy: Guillermo, Bordanaba-Florit; Félix, Royo; Oihane E, Albóniga; Aled, Clayton; Juan Manuel, Falcón-Pérez; Jason, Webber
Opublikowane w: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2024, ISSN 0925-4439
Wydawca: Elsevier
DOI: 10.1016/J.BBADIS.2024.167229

Reproducibility of extracellular vesicle research

Autorzy: Rossella Crescitelli; Juan Falcon‐Perez; An Hendrix; Metka Lenassi; Le Thi Nguyet Minh; Takahiro Ochiya; Nicole Noren Hooten; Ursula Sandau; Clotilde Théry; Rienk Nieuwland
Opublikowane w: Journal of Extracellular Vesicles, 2025, ISSN 2001-3078
Wydawca: Wiley
DOI: 10.1002/JEV2.70036

Curcumin encapsulated in milk small extracellular vesicles as a nanotherapeutic alternative in experimental chronic liver disease

Autorzy: Virginia Albaladejo-García, Laura Morán, Ana Santos-Coquillat, María I. González, Hui Ye, Elena Vázquez Ogando, Javier Vaquero, Francisco Javier Cubero, Manuel Desco, Beatriz Salinas
Opublikowane w: Biomedicine & Pharmacotherapy, 2024, ISSN 1950-6007
Wydawca: Elsevier
DOI: 10.1016/J.BIOPHA.2024.116381

HILPDA, a new player in NASH-driven HCC, links hypoxia signaling with ceramide synthesis

Autorzy: Jose C Fernandez-Checa 1, Sandra Torres 2, Carmen Garcia-Ruiz 3
Opublikowane w: Journal of Hepatology, ISSN 0168-8278
Wydawca: Elsevier
DOI: 10.1016/J.JHEP.2023.05.009

GDF15 is associated with hepatocellular senescence and correlates with mortality in patients with alcohol-associated hepatitis

Autorzy: Teresa Rubio-Tomás; David Martí-Aguado; Delia Blaya; Silvia Ariño; Beatriz Aguilar-Bravo; Raquel A. Martínez García de la Torre; Marc Miravet-Marti; Raquel Ferrer-Lorente; Laura Zanatto; Zengqing Xu; Laura Garcia-Tercero; Carlos Mateos-Sánchez; Juan José Lozano; Isabella Dotti; Johanne Poisson; Marion Tanguy; Azucena Salas; Pierre-Emmanuel Rautou; Ramon Bataller; Pau Sancho-Bru
Opublikowane w: JHEP Reports, 2025, ISSN 2589-5559
Wydawca: Elsevier
DOI: 10.1016/J.JHEPR.2025.101478

Identification of PRMT5 as a therapeutic target in cholangiocarcinoma

Autorzy: Jasmin Elurbide, Leticia Colyn, Maria U Latasa, Iker Uriarte, Stefano Mariani, Amaya Lopez-Pascual, Emiliana Valbuena, Borja Castello-Uribe, Robert Arnes-Benito, Elena Adan-Villaescusa, Luz A Martinez-Perez, Mikel Azkargorta, Felix Elortza, Hanghang Wu, Marcin Krawczyk, Kai Markus Schneider, Bruno Sangro, Luca Aldrighetti, Francesca Ratti, Andrea Casadei Gardini, Jose J G Marin, Irene Amat, Jesus M Urman, Maria Arechederra, Maria Luz Martinez-Chantar, Christian Trautwein, Meritxell Huch, Francisco Javier Cubero, Carmen Berasain, Maite G Fernandez-Barrena, Matias A Avila
Opublikowane w: Gut, Numer 74, 2024, ISSN 0017-5749
Wydawca: BMJ
DOI: 10.1136/gutjnl-2024-332998

Dietary and genetic disruption of hepatic methionine metabolism induce acid sphingomyelinase to promote steatohepatitis

Autorzy: Cristina Alarcón-Vila 1, Naroa Insausti-Urkia 1, Sandra Torres 1, Paula Segalés-Rovira 1, Laura Conde de la Rosa 1, Susana Nuñez 1, Raquel Fucho 1, Jose C Fernández-Checa 2, Carmen García-Ruiz 3
Opublikowane w: Redox Biology, 2022, ISSN 2213-2317
Wydawca: Elsevier BV
DOI: 10.1016/J.REDOX.2022.102596

Tumor progression locus 2 (TPL2): A Cot-plicated progression from inflammation to chronic liver disease

Autorzy: Alejandro H Gutierrez 1, Marina S Mazariegos 1, Susana Alemany 2, Yulia A Nevzorova 3, Francisco Javier Cubero 3, Carlos Sanz-García 4
Opublikowane w: Molecular Basis of disease, 2023, ISSN 0925-4439
Wydawca: Elsevier
DOI: 10.1016/J.BBADIS.2023.166660

Bile acids in liver and gastrointestinal cancer

Autorzy: Maria J. Monte, Laura Fàbrega, Marta R. Romero, Alvaro G. Temprano, Neil Kaplowitz, Carmen Garcia-Ruiz, Jose J.G. Marin, Jose C. Fernandez-Checa
Opublikowane w: Seminars in Cancer Biology, Numer 116, 2025, ISSN 1044-579X
Wydawca: Elsevier BV
DOI: 10.1016/J.SEMCANCER.2025.09.002

Expression of SREBF2 and HMGCR discriminates the viability of steatotic grafts for human liver transplantation

Autorzy: Anna Baulies, Sandra Torres, Raquel Fucho, Susana Núñez, Ferran Torres, Joana Ferrer-Fàbrega, Alba Díaz, Naira Rico, Juan Carlos García-Valdecasas, Josep Fuster, Ramon Adalia, David Paredes, Anto
Opublikowane w: Journal of Lipid Research, Numer 66, 2025, ISSN 0022-2275
Wydawca: Elsevier BV
DOI: 10.1016/J.JLR.2025.100901

Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis

Autorzy: Arantza Lamas-Paz, Alejandro Hionides-Gutiérrez, Feifei Guo, Gonzalo Jorquera, Laura Morán-Blanco, Raquel Benedé-Ubieto, Mariana Mesquita, Olga Estévez-Vázquez, Kang Zheng, Marina Mazariegos, Elena Vázquez-Ogando, Elena Blázquez-López, Iris Asensio, Beste Mutlu, Beatriz Gomez-Santos, María Isabel Peligros, Javier Vaquero, Rafael Bañares, Teresa C. Delgado, María Luz Martínez-Chantar, Eduardo Martínez-Naves, Carlos Sanz-García, Mohamed Ramadan Mohamed, Sofía Tesolato, Pilar Iniesta, Rocío Gallego-Durán, Douglas Maya-Miles, Javier Ampuero, Manuel Romero-Gómez, Ana Martínez-Alcocer, David Sanfeliu-Redondo, Anabel Fernández-Iglesias, Jordi Gracia-Sancho, Mar Coll, Isabel Graupera, Pere Ginès, Andrea Ciudin, Jesús Rivera-Esteban, Juan M. Pericàs, Matías A. Ávila, Maria Dolores Frutos, Carlos Manuel Martínez-Cáceres, Bruno Ramos-Molina, Patricia Aspichueta, Pere Puigserver, Yulia A. Nevzorova, Francisco Javier Cubero
Opublikowane w: JHEP Reports, Numer 7, 2025, ISSN 2589-5559
Wydawca: Elsevier BV
DOI: 10.1016/j.jhepr.2024.101230

Zebrafish as a model for drug induced liver injury: state of the art and beyond

Autorzy: Gulcin Cakan-Akdogan, Abdul Moiz Aftab, Muazzez Celebi Cinar, Khalid A. Abdelhalim, Ozlen Konu
Opublikowane w: Exploration of Digestive Diseases, 2023, ISSN 2833-6321
Wydawca: Open Exploration Publishing
DOI: 10.37349/EDD.2023.00017

Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet

Autorzy: M.I. Lucena, M. Villanueva-Paz, I. Alvarez-Alvarez, G.P. Aithal, E.S. Björnsson, G. Cakan-Akdogan, F.J. Cubero, F. Esteves , J.M. Falcon-Perez , B. Fromenty, C. Garcia-Ruiz, J.I. Grove, O. Konu, M. Kranendonk, G.A. Kullak-Ublick, J.P. Miranda, et al.
Opublikowane w: Pharmacological Research, 2023, ISSN 1043-6618
Wydawca: Elsevier
DOI: 10.1016/J.PHRS.2023.107046

The Cantabria Cohort, a protocol for a population-based cohort in northern Spain

Autorzy: Marta Alonso-Peña, Trinidad Dierssen, Maria José Marin, Jessica Alonso-Molero, Inés Gómez-Acebo, Inés Santiuste, Jeffrey V. Lazarus, Pascual Sanchez-Juan, Galo Peralta, Javier Crespo, Marcos Lopez-Hoyos & Cantabria Cohort Collaborators
Opublikowane w: BMC Public Health, 2023, ISSN 1471-2458
Wydawca: BioMed Central
DOI: 10.1186/S12889-023-17318-8

Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress

Autorzy: Beatriz Martín-Adrados; Stefanie K. Wculek; Sergio Fernández-Bravo; Raúl Torres-Ruiz; Ana Valle-Noguera; Maria José Gomez-Sánchez; José Carlos Hernández-Walias; Frederico Moraes Ferreira; Ana María Corraliza; David Sancho; Vanesa Esteban; Sandra Rodriguez-Perales; Aránzazu Cruz-Adalia; Helder I. Nakaya; Azucena Salas; David Bernardo; Yolanda Campos-Martín; Elena Martínez-Zamorano; Diego Muñoz-López; Manuel Gómez del Moral; Francisco Javier Cubero; Richard S. Blumberg; Eduardo Martínez-Naves
Opublikowane w: Frontiers in Inmmunology, 2023, ISSN 1664-3224
Wydawca: Frontiers
DOI: 10.3389/fimmu.2023.1185517

Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis

Autorzy: Zheng K, Hao F, Medrano-Garcia S, Chen C, Guo F, Morán-Blanco L, Rodríguez-Perales S, Torres-Ruiz R, Peligros MI, Vaquero J, Bañares R, Gómez Del Moral M, Regueiro JR, Martínez-Naves E, Mohamed MR, Gallego-Durán R, Maya D, Ampuero J, Romero-Gómez M, Gilbe
Opublikowane w: Cell Death and Disease, 2023, ISSN 2041-4889
Wydawca: Nature Publishing Group
DOI: 10.1038/S41419-023-06029-Y

Zonal expression of StARD1 and oxidative stress in alcoholic-related liver disease

Autorzy: Raquel Fucho 1, Estel Solsona-Vilarrasa 1, Sandra Torres 1, Susana Nuñez 1, Naroa Insausti-Urkia 1, Albert Edo 1, Maria Calvo 2, Anna Bosch 2, Gemma Martin 2, Carlos Enrich 3, Carmen García-Ruiz 4, Jose C Fernandez-Checa
Opublikowane w: J Lipid Res, 2023, ISSN 0022-2275
Wydawca: Elsevier
DOI: 10.1016/J.JLR.2023.100413

Control compounds for preclinical drug-induced liver injury assessment: Consensus-driven systematic review by the ProEuroDILI network

Autorzy: Antonio Segovia-Zafra, Marina Villanueva-Paz, Ana Sofia Serras, Gonzalo Matilla-Cabello, Ana Bodoque-García, Daniel E. Di Zeo-Sánchez, Hao Niu, Ismael Álvarez-Álvarez, Laura Sanz-Villanueva, Sergej Godec, Irina Milisav, Pierre Bagnaninchi, Raúl J. Andrade, M Isabel Lucena, José C. Fernández-Checa, Francisco Javier Cubero, Joana Paiva Miranda, Leonard J. Nelson
Opublikowane w: Journal of Hepatology, Numer 81, 2024, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/J.JHEP.2024.04.026

CMGH Cellular and Molecular Gastroenterology and Hepatology

Autorzy: Mohamed Ramadan Mohamed 1, Gang Zhao 2, Ines Volkert 3, Antonio Molinaro 4, Carolin V Schneider 3, Pavel Strnad 3, Jan G Hengstler 5, Chi Xu 6, Roger J Davis 7, Kai Markus Schneider 3, Francisco Javier Cubero 8, Christian Trautwein 9
Opublikowane w: Cell Mol Gastroenterol Hepatol ., ISSN 2352-345X
Wydawca: Elsevier
DOI: 10.1016/J.JCMGH.2025.101588

Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential

Autorzy: Maria Mercado-Gómez, Naroa Goikoetxea-Usandizaga, Alvaro Eguileor Giné, Miguel A Merlos Rodrigo, Marta Bento Afonso, Mikel Azkargorta, Leidy Estefanía Zapata-Pavas, Claudia M Rejano-Gordillo, Marta R Romero, Isabel Mendizabal, Pedro M Rodrigues, Hanghang Wu, Rubén Rodríguez-Agudo, Marina Serrano-Maciá, Paula Olaizola, Jon Ander Barrenechea-Barrenechea, Irene González Recio, Maite G Fernandez-Barrena, Diletta Overi, Eugenio Gaudio, Ute Schaeper, Saioa Garcia-Longarte, Mariana Yáñez-Bartolomé, Patricia Peña-SanFelix, Clàudia Gil-Pitarch, Ainhoa Lapitz, Hana Michalkova, Zbynek Heger, Carolina Conter, Rocio I R Macias, Arkaitz Carracedo, Jesús Bañales, Victor Moreno, Angela Lamarca, Rajat Singh, Teresa Cardoso Delgado, Luis Alfonso Martínez-Cruz, Felix Elortza, Matias A Avila, César Martín, Tian V. Tian, Teresa Macarulla, Daniela Buccella, Francisco Javier Cubero, Diego F Calvisi, Guido Carpino, Jose J G Marin, Cecília M P Rodrigues, Maria Luz Martinez-Chantar
Opublikowane w: Gut, 2025, ISSN 0017-5749
Wydawca: BMJ
DOI: 10.1136/GUTJNL-2024-333255

Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases

Autorzy: Ana I. Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana Sofia Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot-Przeczek, Sentiljana Gumeni, José Jimenez-Ville
Opublikowane w: Redox Biology, Numer 79, 2025, ISSN 2213-2317
Wydawca: Elsevier BV
DOI: 10.1016/J.REDOX.2024.103464

Intestinal permeability and immune‐inflammatory markers in patients with idiosyncratic drug‐induced liver injury, drug‐induced steatosis and metabolic dysfunction–associated steatotic liver disease (MASLD)

Autorzy: Daniel E. Di Zeo‐Sánchez, Irene Díaz‐Alberola, José María Pinazo‐Bandera, Miren García‐Cortés, Judith Sanabria‐Cabrera, Mercedes Robles‐Díaz, Ismael Álvarez‐Álvarez, M. Isabel Lucena, Raúl J. Andrade, Marina Villanueva‐Paz, Camilla Stephens
Opublikowane w: British Journal of Pharmacology, Numer 182, 2025, ISSN 0007-1188
Wydawca: Wiley
DOI: 10.1111/BPH.70123

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol

Autorzy: Arantza Lamas-Paz, Mariana Mesquita, Marcos Garcia-Lacarte, Olga Estévez-Vázquez, Raquel Benedé-Ubieto, Alejandro H. Gutierrez, Hanghang Wu, Hector Leal Lasalle, Javier Vaquero, Rafael Bañares, Eduardo Martínez-Naves, Sergio Roa, Yulia A. Nevzorova, Gonzalo Jorquera, Francisco Javier Cubero
Opublikowane w: Frontiers in Nutrition, Numer 11, 2024, ISSN 2296-861X
Wydawca: Frontiers Media SA
DOI: 10.3389/fnut.2024.1393014

Fecal Microbiota Transplantation from Young-Trained Donors Improves Cognitive Function in Old Mice Through Modulation of the Gut-Brain Axis

Autorzy: Camila Cerna, Nicole Vidal-Herrera, Francisco Silva- Olivares, et al.
Opublikowane w: Aging and disease, ISSN 2152-5250
Wydawca: International Society on Aging and Disease.
DOI: 10.14336/AD.2024.1089

Development and validation of a precise and accurate method to determine polyamine levels in cultured cells

Autorzy: Diana Cabrera; Mikel Pujana Vaquerizo; Belén Martínez La Osa; Amaia Zabala Letona; Arkaitz Carracedo; Juan Manuel Falcón; Sebastiaan van Liempd
Opublikowane w: Crossref, 2025, ISSN 2692-8205
Wydawca: BioRxiv
DOI: 10.1101/2025.05.29.654479

Palmitoylcarnitine impairs immunity in decompensated cirrhosis

Autorzy: Ingrid Wei Zhang; María Belén Sánchez-Rodríguez; Cristina López-Vicario; Mireia Casulleras; Marta Duran-Güell; Roger Flores-Costa; Ferran Aguilar; Michael Rothe; Paula Segalés; Carmen García-Ruiz; José C. Fernández-Checa; Jonel Trebicka; Vicente Arroyo; Joan Clària
Opublikowane w: JHEP Reports, 2024, ISSN 2589-5559
Wydawca: Elsevier
DOI: 10.1016/J.JHEPR.2024.101187

S-Adenosyl-l-methionine restores brain mitochondrial membrane fluidity and GSH content improving Niemann-Pick type C disease

Autorzy: Leire Goicoechea 1, Sandra Torres 1, Laura Fàbrega 1, Mónica Barrios 1, Susana Núñez 2, Josefina Casas 3, Gemma Fabrias 3, Carmen García-Ruiz 4, José C Fernández-Checa 5
Opublikowane w: Redox Biology, 2024, ISSN 2213-2317
Wydawca: Elsevier
DOI: 10.1016/J.REDOX.2024.103150

Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism

Autorzy: Esteves, F.; Almeida, C.M.M.; Silva, S.; Saldanha, I.; Urban, P.; Rueff, J.; Pompon, D.; Truan, G.; Kranendonk, M.
Opublikowane w: Biomolecules, 2023, ISSN 2218-273X
Wydawca: MDPI
DOI: 10.3390/biom13071083

Breaking the barriers: the role of gut homeostasis in Metabolic-Associated Steatotic Liver Disease (MASLD)

Autorzy: Raquel Benedé, Francisco Javier Cubero, Yulia A. Nevzorova
Opublikowane w: Gut microbes, Numer 1, 2331460, 2024, ISSN 1949-0984
Wydawca: Taylor & Francis
DOI: 10.1080/19490976.2024.2331460

Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification

Autorzy: H. Niu, P. Solis-Muñoz, M. García-Cortés, J. Sanabria-Cabrera, M. Robles-Diaz, R. Romero-Flores, E. Bonilla-Toyos, A. Ortega-Alonso, J. M. Pinazo-Bandera, M. R. Cabello, F. Bessone, N. Hernandez, M. I. Lucena, R. J Andrade, I. Medina-Caliz, I. Álvarez-Álv
Opublikowane w: Pharmacological Research, Numer 199, 2024, ISSN 1043-6618
Wydawca: Academic Press
DOI: 10.1016/j.phrs.2023.107030

CAP-RNAseq: an integrated pipeline for functional annotation and prioritization of co-expression clusters

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Wydawca: Oxford Journals
DOI: 10.1093/bib/bbad536

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Wydawca: Wolters Kluwer Health
DOI: 10.1097/HC9.0000000000000541

Unraveling MASLD: The Role of Gut Microbiota, Dietary Modulation, and AI-Driven Lifestyle Interventions

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Wydawca: MDPI AG
DOI: 10.3390/NU17091580

Inhibition of ALK3-mediated signalling pathway protects against acetaminophen-induced liver injury

Autorzy: Patricia Marañón 1, Esther Rey 2, Stephania C Isaza 2, Hanghang Wu 3, Patricia Rada 4, Carmen Choya-Foces 2, Antonio Martínez-Ruiz 5, María Ángeles Martín 6, Sonia Ramos 6, Carmelo García-Monzón 2, Francisco Javier Cubero 7, Ángela M Valverde 4, Águeda Go
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Wydawca: Elsevier
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Epigenetic modifications in drug‐induced liver injury: A systematic review

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Wydawca: Wiley
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Atypical and fatal presentation of acute liver failure

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Wydawca: Elsevier BV
DOI: 10.1016/j.gastre.2024.502207

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