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Wireless Stent-like Soft Millirobots (STENTBOT) for Minimally Invasive Brain Vasculature Disease Treatments

Project description

Robotic treatment of brain vasculature conditions

The brain vasculature provides the nutrients necessary for the function of the central nervous system. Disruption by acute ischemic stroke or aneurysm can have a detrimental impact on patient health. Funded by the European Research Council, the STENTBOT project proposes a robotic approach to reach distant sites of the brain and save the lives of patients. The STENTBOT introduces a wireless magnetic soft robot that can be guided to position by medical imaging and external magnetic actuation. The robot will deliver thrombolytic drugs or repair sites of aneurysms, offering a minimally invasive approach to treating brain vasculature issues.

Objective

Diseases in the brain vasculature, such as acute ischemic stroke, aneurysm and brain tumors, are fatal and require medical devices to treat them with minimal invasion. However, current tethered devices have limited safe access into the distal or tortuous vascular routes, which prevent saving lives of some patients. Therefore, we propose a wireless stent-shaped magnetic soft millirobot, stentbot, which would have the capability of safe access to such routes. Also, the stentbot will be able to be repositioned afterwards without repeating the same procedure fully again if the disease location changes or if the initial position of the device is observed to be not optimal. Such robot concept was originated in the ERC-AdG project of the PI. After reaching its target location safely and precisely under medical imaging and external magnetic actuation guidance, the robot will deliver the tissue plasminogen activator drugs on-demand locally to treat the acute ischemic stroke. Moreover, the robot will be used to treat aneurysms minimally invasively by becoming a flow diverter to regulate flow into the aneurysm sites.

Host institution

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Net EU contribution
€ 150 000,00
Address
HOFGARTENSTRASSE 8
80539 Munchen
Germany

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Links
Total cost
No data

Beneficiaries (1)