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CORDIS - Risultati della ricerca dell’UE
CORDIS

IMPlementing geriatric assessment for dose Optimization of CDK 4/6-inhibitors in older bReasT cAncer patieNTs

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

D6.8 Second conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster (si apre in una nuova finestra)

A second report with concluding remarks from the meetings within the ‘Diagnosis and treatment’ cluster. The deliverable will be prepared within one month after the meeting.

D6.9 Second policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting (si apre in una nuova finestra)

A second policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting. The deliverable will be prepared within one month after the meeting.

D6.1 Dissemination, exploitation, standardization and sustainability plan (si apre in una nuova finestra)

This deliverable will report plan for IMPORTANTs exploitation, dissemination and communication activities.

D2.2 IMPORTANT's technical requirements and specifications (si apre in una nuova finestra)

This deliverable reports the technical requirements and specifications

D6.6 First conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster (si apre in una nuova finestra)

A report with concluding remarks from the meetings within the Diagnosis and treatment cluster. The deliverable will be prepared within one month after the meeting

D6.7 First policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting (si apre in una nuova finestra)

A policy brief formulating recommendations based on the research and innovation strand of the Diagnosis and treatment annual cluster meeting. The deliverable will be prepared within one month after the meeting.

D2.3 - IMPORTANT trial: Regulatory background, policy-related aspects, and standard-of-care (si apre in una nuova finestra)

This report will describe the regulatory and policy aspects related to the design and execution of IMPORTANT trial and will present the current standard-of-care.

D2.1 Breast cancer challenges and clinical study requirements (si apre in una nuova finestra)

This report will include the definition of the clinical requirements for the IMPORTANT study, also covering patients' aspects

D6.5 Initial common work plan for scientific collaboration under the ‘Diagnosis and treatment’ cluster. (si apre in una nuova finestra)

The project will contribute to the annual cluster meeting addressing common scientific challenges, organised in close collaboration with the European Commission. Relevant national ministries, agencies and policymakers, as well as other related EU-funded projects, will be invited to these annual meetings.

Pubblicazioni

Implementing geriatric assessment for dose optimization of CDK 4/6 inhibitors in older breast cancer patients (IMPORTANT trial): A pragmatic randomized-controlled trial. (si apre in una nuova finestra)

Autori: Antonios Valachis, Laura Biganzoli, Athina Christopoulou, Kamilla Fjermeros, Eleni Fountzila, Jürgen Geisler, Raquel Gomez-Bravo, Peeter Karihtala, Paris A. Kosmidis, Angelos Koutras, Helena Linardou, Henrik Lindman, Icro Meattini, Montserrat Muñoz, Amanda Psyrri, Emanuela Risi, Aglaia Schiza, Meri Utriainen, Luca Visani, Thanos Kosmidis
Pubblicato in: Journal of Clinical Oncology, Numero 42, 2024, ISSN 0732-183X
Editore: American Society of Clinical Oncology (ASCO)
DOI: 10.1200/JCO.2024.42.16_SUPPL.TPS1132

Clinical trials in older patients with cancer – typical challenges, possible solutions, and a paradigm of study design in breast cancer. (si apre in una nuova finestra)

Autori: Karihtala, P., Schiza, A., Fountzilas, E., Geisler, J., Meattini, I., Risi, E., Biganzoli, L., & Valchis, A.
Pubblicato in: Acta Oncologica, Numero 63(1), 2024, ISSN 1651-226X
Editore: Medical Journals Sweden AB
DOI: 10.2340/1651-226X.2023.40365

262TiP PROVIDENCE: A prospective, non-interventional study examining real-world clinical and patient-reported outcome (PRO) data in patients (pts) with HER2-positive or HER2-low unresectable or metastatic breast cancer (mBC) treated with trastuzumab deruxtecan (si apre in una nuova finestra)

Autori: M.K. Welslau, M. Schmidt, R. Würstlein, S. Briest, D. Holdhof, B. Edlich, H. Tesch
Pubblicato in: ESMO Open, Numero 9, 2024, ISSN 2059-7029
Editore: Elsevier BV
DOI: 10.1016/J.ESMOOP.2024.103283

A Swarm-Based Clinical Validation Framework of Artificial Intelligence Solutions for Non-Communicable Diseases (si apre in una nuova finestra)

Autori: Kitty Kioskli, Spyridon Papastergiou, Theofanis Fotis
Pubblicato in: Journal of Engineering Research and Sciences, 2023, ISSN 2831-4085
Editore: Journal of Engineering Research and Sciences (Standalone)
DOI: 10.55708/js0209001

Implementing geriatric assessment for dose optimization of CDK4/6 inhibitors in older breast cancer patients (si apre in una nuova finestra)

Autori: Antonis Valachis, Laura Biganzoli, Athina Christopoulou, Kamilla Fjermeros, Elena Fountzila, Jürgen Geisler, Raquel Gomez-Bravo, Peeter Karihtala, Paris Kosmidis, Angelos Koutras, Helena Linardou, Henrik Lindman, Iván Martínez-Ballestero, Anna Belén Rodríguez, Icro Meattini, Montserrat Munoz-Mateu, Mukhrizah Othman, Amanda Psyrri, Emanuela Risi, Aglaia Schiza, Nikolaos Spathas, Meri Utriainen, Luca Visani, Soledad Ballesteros, Ioannis Basdekis, Susanne Dieroff Hay, Theo Fotis, Samuel Fricker, Gimon de Graaf, Marit Jenset, Tim Kanters, Kostas Lampropoulos, Christiana Markou, Kalliopi Mastoraki, Christina Nanou, José Manuel Reales Aviles, Marianne Santaholma, Thanos Kosmidis
Pubblicato in: Future Oncology, 2024, ISSN 1479-6694
Editore: Informa UK Limited
DOI: 10.1080/14796694.2024.2413841

Towards Personalised Digital Support: Clinician Perspectives on Patient Recruitment and Retention in Decentralised Clinical Trials (si apre in una nuova finestra)

Autori: M. R. Yeganeh and S. A. Fricker
Editore: 025 IEEE 33rd International Requirements Engineering Conference Workshops (REW), Valencia, Spain, 2025, pp. 578-587
DOI: 10.1109/REW66121.2025.00086

The effectiveness of physical activity on psychological and physical well-being in older breast cancer patients: A systematic review and meta-analysis

Autori: Soledad Ballesteros, Pilar Jimenzes, Jennifer A. Rieker, José Manuel Reales
Pubblicato in: PhysAgeNet & EGRAPA Conference 2024 “Evidence Based Physical Activity in Old Age”
Editore: PhysAgeNet & EGRAPA Conference 2024

Vision for a Digital Service to Facilitate Recruitment and Retention of Older Patients in Clinical Trials (si apre in una nuova finestra)

Autori: Maryam R. Yeganeh, Samuel A. Fricker
Pubblicato in: 2024 IEEE 32nd International Requirements Engineering Conference Workshops (REW), 2024
Editore: IEEE
DOI: 10.1109/REW61692.2024.00061

“Yes, I Will!”: Expert Perspectives on Digital Support for Patient Participation in Breast Cancer Clinical Trial (si apre in una nuova finestra)

Autori: Maryam R. Yeganeh, Samuel A. Fricker, Elaine M. Huang
Pubblicato in: Lecture Notes in Computer Science, Persuasive Technology, 2026, ISBN 978-3-032-19687-3
Editore: Springer Nature Switzerland
DOI: 10.1007/978-3-032-19687-3_21

Markov decision process, treatment optimization, Monte Carlo simulation, frailty, geriatric oncology

Autori: P. Karampelesis, S. Denazis, E.I. Zacharaki
Editore: University of Patras

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