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CORDIS

IMPlementing geriatric assessment for dose Optimization of CDK 4/6-inhibitors in older bReasT cAncer patieNTs

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

D6.8 Second conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster (öffnet in neuem Fenster)

A second report with concluding remarks from the meetings within the ‘Diagnosis and treatment’ cluster. The deliverable will be prepared within one month after the meeting.

D6.9 Second policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting (öffnet in neuem Fenster)

A second policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting. The deliverable will be prepared within one month after the meeting.

D6.1 Dissemination, exploitation, standardization and sustainability plan (öffnet in neuem Fenster)

This deliverable will report plan for IMPORTANTs exploitation, dissemination and communication activities.

D2.2 IMPORTANT's technical requirements and specifications (öffnet in neuem Fenster)

This deliverable reports the technical requirements and specifications

D6.6 First conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster (öffnet in neuem Fenster)

A report with concluding remarks from the meetings within the Diagnosis and treatment cluster. The deliverable will be prepared within one month after the meeting

D6.7 First policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting (öffnet in neuem Fenster)

A policy brief formulating recommendations based on the research and innovation strand of the Diagnosis and treatment annual cluster meeting. The deliverable will be prepared within one month after the meeting.

D2.3 - IMPORTANT trial: Regulatory background, policy-related aspects, and standard-of-care (öffnet in neuem Fenster)

This report will describe the regulatory and policy aspects related to the design and execution of IMPORTANT trial and will present the current standard-of-care.

D2.1 Breast cancer challenges and clinical study requirements (öffnet in neuem Fenster)

This report will include the definition of the clinical requirements for the IMPORTANT study, also covering patients' aspects

D6.5 Initial common work plan for scientific collaboration under the ‘Diagnosis and treatment’ cluster. (öffnet in neuem Fenster)

The project will contribute to the annual cluster meeting addressing common scientific challenges, organised in close collaboration with the European Commission. Relevant national ministries, agencies and policymakers, as well as other related EU-funded projects, will be invited to these annual meetings.

Veröffentlichungen

Implementing geriatric assessment for dose optimization of CDK 4/6 inhibitors in older breast cancer patients (IMPORTANT trial): A pragmatic randomized-controlled trial. (öffnet in neuem Fenster)

Autoren: Antonios Valachis, Laura Biganzoli, Athina Christopoulou, Kamilla Fjermeros, Eleni Fountzila, Jürgen Geisler, Raquel Gomez-Bravo, Peeter Karihtala, Paris A. Kosmidis, Angelos Koutras, Helena Linardou, Henrik Lindman, Icro Meattini, Montserrat Muñoz, Amanda Psyrri, Emanuela Risi, Aglaia Schiza, Meri Utriainen, Luca Visani, Thanos Kosmidis
Veröffentlicht in: Journal of Clinical Oncology, Ausgabe 42, 2024, ISSN 0732-183X
Herausgeber: American Society of Clinical Oncology (ASCO)
DOI: 10.1200/JCO.2024.42.16_SUPPL.TPS1132

Clinical trials in older patients with cancer – typical challenges, possible solutions, and a paradigm of study design in breast cancer. (öffnet in neuem Fenster)

Autoren: Karihtala, P., Schiza, A., Fountzilas, E., Geisler, J., Meattini, I., Risi, E., Biganzoli, L., & Valchis, A.
Veröffentlicht in: Acta Oncologica, Ausgabe 63(1), 2024, ISSN 1651-226X
Herausgeber: Medical Journals Sweden AB
DOI: 10.2340/1651-226X.2023.40365

262TiP PROVIDENCE: A prospective, non-interventional study examining real-world clinical and patient-reported outcome (PRO) data in patients (pts) with HER2-positive or HER2-low unresectable or metastatic breast cancer (mBC) treated with trastuzumab deruxtecan (öffnet in neuem Fenster)

Autoren: M.K. Welslau, M. Schmidt, R. Würstlein, S. Briest, D. Holdhof, B. Edlich, H. Tesch
Veröffentlicht in: ESMO Open, Ausgabe 9, 2024, ISSN 2059-7029
Herausgeber: Elsevier BV
DOI: 10.1016/J.ESMOOP.2024.103283

A Swarm-Based Clinical Validation Framework of Artificial Intelligence Solutions for Non-Communicable Diseases (öffnet in neuem Fenster)

Autoren: Kitty Kioskli, Spyridon Papastergiou, Theofanis Fotis
Veröffentlicht in: Journal of Engineering Research and Sciences, 2023, ISSN 2831-4085
Herausgeber: Journal of Engineering Research and Sciences (Standalone)
DOI: 10.55708/js0209001

Implementing geriatric assessment for dose optimization of CDK4/6 inhibitors in older breast cancer patients (öffnet in neuem Fenster)

Autoren: Antonis Valachis, Laura Biganzoli, Athina Christopoulou, Kamilla Fjermeros, Elena Fountzila, Jürgen Geisler, Raquel Gomez-Bravo, Peeter Karihtala, Paris Kosmidis, Angelos Koutras, Helena Linardou, Henrik Lindman, Iván Martínez-Ballestero, Anna Belén Rodríguez, Icro Meattini, Montserrat Munoz-Mateu, Mukhrizah Othman, Amanda Psyrri, Emanuela Risi, Aglaia Schiza, Nikolaos Spathas, Meri Utriainen, Luca Visani, Soledad Ballesteros, Ioannis Basdekis, Susanne Dieroff Hay, Theo Fotis, Samuel Fricker, Gimon de Graaf, Marit Jenset, Tim Kanters, Kostas Lampropoulos, Christiana Markou, Kalliopi Mastoraki, Christina Nanou, José Manuel Reales Aviles, Marianne Santaholma, Thanos Kosmidis
Veröffentlicht in: Future Oncology, 2024, ISSN 1479-6694
Herausgeber: Informa UK Limited
DOI: 10.1080/14796694.2024.2413841

Towards Personalised Digital Support: Clinician Perspectives on Patient Recruitment and Retention in Decentralised Clinical Trials (öffnet in neuem Fenster)

Autoren: M. R. Yeganeh and S. A. Fricker
Herausgeber: 025 IEEE 33rd International Requirements Engineering Conference Workshops (REW), Valencia, Spain, 2025, pp. 578-587
DOI: 10.1109/REW66121.2025.00086

The effectiveness of physical activity on psychological and physical well-being in older breast cancer patients: A systematic review and meta-analysis

Autoren: Soledad Ballesteros, Pilar Jimenzes, Jennifer A. Rieker, José Manuel Reales
Veröffentlicht in: PhysAgeNet & EGRAPA Conference 2024 “Evidence Based Physical Activity in Old Age”
Herausgeber: PhysAgeNet & EGRAPA Conference 2024

Vision for a Digital Service to Facilitate Recruitment and Retention of Older Patients in Clinical Trials (öffnet in neuem Fenster)

Autoren: Maryam R. Yeganeh, Samuel A. Fricker
Veröffentlicht in: 2024 IEEE 32nd International Requirements Engineering Conference Workshops (REW), 2024
Herausgeber: IEEE
DOI: 10.1109/REW61692.2024.00061

“Yes, I Will!”: Expert Perspectives on Digital Support for Patient Participation in Breast Cancer Clinical Trial (öffnet in neuem Fenster)

Autoren: Maryam R. Yeganeh, Samuel A. Fricker, Elaine M. Huang
Veröffentlicht in: Lecture Notes in Computer Science, Persuasive Technology, 2026, ISBN 978-3-032-19687-3
Herausgeber: Springer Nature Switzerland
DOI: 10.1007/978-3-032-19687-3_21

Markov decision process, treatment optimization, Monte Carlo simulation, frailty, geriatric oncology

Autoren: P. Karampelesis, S. Denazis, E.I. Zacharaki
Herausgeber: University of Patras

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