Comparative HaplotypOmics of Parthenogenetic Plectus nEmatodes

Project Information

CHOPPE

Grant agreement ID: 101110569

DOI 10.3030/101110569

EC signature date 17 March 2023

Start date 1 May 2023

End date 30 April 2025

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost No data

EU contribution € 173 847,36

Coordinated by

UNIVERSITAT ZU KOLN
Germany

Objective

Sexual reproduction is a costly but seemingly necessary trait in animals. However, species in diverse branches of the animal kingdom have secondarily reverted to asexual reproduction. In the roundworms (phylum Nematoda), this reversal appears particularly frequent, as parthenogenetic species have emerged in numerous genera. Species in the genus Plectus are obligately parthenogenetic, and are distributed in non-extreme and extreme environments across the globe. Mechanisms leading to the loss of sex, for example hybridisation, have received some attention, but are still poorly understood, in particular on the genomic level. This is in part due to the lack of sequencing and analysis tools for complex genomes of minute organisms.
CHOPPE will generate chromosome-level collapsed and phased genome assemblies using latest assembly strategies for several species of Plectus and its closest sexual relative Anaplectus from diverse habitats. CHOPPE will develop new computational methods for generating fully phased assemblies of diverse non-model species. Collapsed assemblies, and haplotype assemblies of several Plectus and Anaplectus species generated in the project, will allow to decipher the genomic basis of their adaption in the context of parthenogenesis and extreme environments. The project will further investigate the reversal to sexuality of Plectus through crossing with heat induced males, and establish this genus as a new model for the study of parthenogenesis.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• natural sciences › computer and information sciences › computational science
• natural sciences › biological sciences › genetics › genomes

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Keywords

• Genome assembly
• Haplotypes
• Parthenogenesis
• Adaptation

Programme(s)

• HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme

Topic(s)

• HORIZON-MSCA-2022-PF-01-01 - MSCA Postdoctoral Fellowships 2022

Call for proposal

HORIZON-MSCA-2022-PF-01

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

Coordinator

UNIVERSITAT ZU KOLN

• Net EU contribution: € 173 847,36
• Address: ALBERTUS MAGNUS PLATZ ; 50931 Koln ; Germany
• Region: Nordrhein-Westfalen › Köln › Köln, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data