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CORDIS - EU research results
CORDIS

MultiomIcs based Risk stratification of Atherosclerotic CardiovascuLar disEase

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

General Assembly Meeting-1 (opens in new window)

Online meeting with Partner PIs. Project planning and tracking report (minutes/PPTs) (Tasks 5.1-2)

Website and project logo (opens in new window)

Website and project logo information with social media links (Task 5.3)

Sex-stratified clusters of plaques (opens in new window)

Define and report sex specific plaque clusters (Task 2.1)

Data Management plan (opens in new window)

Describes the data management life cycle (Task 5.1)

Publications

Evidence of survival bias in the association between APOE-Є4 and age at ischemic stroke onset (opens in new window)

Author(s): Joanna von Berg, Patrick F. McArdle, Paavo Häppölä, Jeffrey Haessler, Charles Kooperberg, Robin Lemmens, Alessandro Pezzini, Vincent Thijs, Sara L. Pulit, Steven J. Kittner, Braxton D. Mitchell, Jeroen de Ridder, Sander W. van der Laan
Published in: Frontiers in Genetics, Issue 15, 2024, ISSN 1664-8021
Publisher: Frontiers Media SA
DOI: 10.3389/fgene.2024.1392061

Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis (opens in new window)

Author(s): Giuseppe Mocci, Katyayani Sukhavasi, Tiit Örd, Sean Bankier, Prosanta Singha, Uma Thanigai Arasu, Olayinka Oluwasegun Agbabiaje, Petri Mäkinen, Lijiang Ma, Chani J. Hodonsky, Redouane Aherrahrou, Lars Muhl, Jianping Liu, Sonja Gustafsson, Byambajav Byandelger, Ying Wang, Simon Koplev, Urban Lendahl, Gary K. Owens, Nicholas J. Leeper, Gerard Pasterkamp, Michael Vanlandewijck, Tom Michoel, Arno Ruusalepp, Ke Hao, Seppo Ylä-Herttuala, Marika Väli, Heli Järve, Michal Mokry, Mete Civelek, Clint J. Miller, Jason C. Kovacic, Minna U. Kaikkonen, Christer Betsholtz, Johan L.M. Björkegren
Published in: Circulation Research, Issue 134, 2024, ISSN 0009-7330
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1161/CIRCRESAHA.123.323184

Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease (opens in new window)

Author(s): Ling Li, Shichao Pang, Fabian Starnecker, Bertram Mueller-Myhsok, Heribert Schunkert
Published in: European Heart Journal, Issue 45, 2024, ISSN 0195-668X
Publisher: Oxford University Press (OUP)
DOI: 10.1093/eurheartj/ehae048

Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro (opens in new window)

Author(s): Ilakya Selvarajan, Miika Kiema, Ru-Ting Huang, Jin Li, Jiayu Zhu, Petri Pölönen, Tiit Örd, Kadri Õunap, Mehvash Godiwala, Anna Kathryn Golebiewski, Aarthi Ravindran, Kiira Mäklin, Anu Toropainen, Lindsey K. Stolze, Maximiliano Arce, Peetra U. Magnusson, Stephen White, Casey E. Romanoski, Merja Heinäniemi, Johanna P. Laakkonen, Yun Fang, Minna U. Kaikkonen
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, Issue 44, 2024, ISSN 1079-5642
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1161/ATVBAHA.123.318964

Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis (opens in new window)

Author(s): Savvina Prapiadou, Luka Živković, Barbara Thorand, Marc J. George, Sander W. van der Laan, Rainer Malik, Christian Herder, Wolfgang Koenig, Thor Ueland, Ola Kleveland, Pål Aukrust, Lars Gullestad, Jürgen Bernhagen, Gerard Pasterkamp, Annette Peters, Aroon D. Hingorani, Jonathan Rosand, Martin Dichgans, Christopher D. Anderson, Marios K. Georgakis
Published in: Circulation, Issue 149, 2024, ISSN 0009-7322
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1161/CIRCULATIONAHA.123.064974

The Effects of FABP4 on Cardiovascular Disease in the Aging Population (opens in new window)

Author(s): Ellen M. van der Ark-Vonk, Mike V. Puijk, Gerard Pasterkamp, Sander W. van der Laan
Published in: Current Atherosclerosis Reports, Issue 26, 2024, ISSN 1523-3804
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/s11883-024-01196-5

Genetic variation drives differences in obesity-related gene regulation (opens in new window)

Author(s): Minna U. Kaikkonen
Published in: Trends in Genetics, Issue 40, 2024, ISSN 0168-9525
Publisher: Elsevier BV
DOI: 10.1016/j.tig.2024.02.009

Tobacco smoking is associated with sex- and plaque-type specific upregulation of CRLF1 in atherosclerotic lesions (opens in new window)

Author(s): Tian Lan, Kaylin C.A. Palm, Luka Hoeben, Ernest Diez Benavente, R. Noah Perry, Mete Civelek, Dominique P.V. de Kleijn, Hester M. den Ruijter, Gerard Pasterkamp, Michal Mokry
Published in: Atherosclerosis, Issue 397, 2024, ISSN 0021-9150
Publisher: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2024.118554

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