Single-nuclei UPR profiling by flow cytometry reveals bortezomib resistance mechanisms in multiple myeloma
(öffnet in neuem Fenster)
Autoren:
Julien P Gigan, Paulina Garcia-Gonzalez, Angelo Pilotti, Lou Galliot, Alexandre Reynaud, Yoan Ghaffar, Felipe Flores-Santibáñez, Sara Ghafoori, Eve Seillier, Rosario Lavignolle-Heguy, Daniela Barros, Caroline Bret, Sharon Fichaux, Alexis Combes, Alessandro Bani, Rejane Rua, Evelina Gatti, Béatrice Nal-Rogier, Stéphane Rocchi, Jérôme Moreaux, Philippe Pierre, Rafael J Argüello
Veröffentlicht in:
EMBO Molecular Medicine, Ausgabe 18, 2026, ISSN 1757-4684
Herausgeber:
Springer Science and Business Media LLC
DOI:
10.1038/S44321-026-00469-7
Induction of the ISR by AB5 subtilase cytotoxin drives type-I IFN expression in pDCs via STING activation
(öffnet in neuem Fenster)
Autoren:
Daniela Barros, Beatriz H. Ferreira, Paulina Garcia-Gonzalez, Francesco Carbone, Marine Luka, Fátima Leite-Pinheiro, Mariana D. Machado, Theopisti Nikolaou, Angelo Pilotti, Eliot Goguet, Paulo Antas, Andreia Mendes, Lichen Zhang, Marina Cresci, Lou Galliot, Julien P. Gigan, Marisa Reverendo, Bing Su, Miwako Narita, Adrienne W. Paton, James C. Paton, Stéphane Rocchi, Frédéric Rieux-Laucat, Rafael J. Argüello, Béatrice Nal, Yinming Liang, Mickaël Ménager, Evelina Gatti, Catarina R. Almeida, Philippe Pierre
Veröffentlicht in:
Proceedings of the National Academy of Sciences, Ausgabe 122, 2025, ISSN 0027-8424
Herausgeber:
Proceedings of the National Academy of Sciences
DOI:
10.1073/PNAS.2421258122