Supple Graphene Bio-Platform for point-of-care early detection and monitoring of Alzheimer’s Disease

Informations projet

2D-BioPAD

N° de convention de subvention: 101120706

DOI

10.3030/101120706

Date de signature de la CE 29 Juin 2023

Date de début 1 Octobre 2023

Date de fin 30 Septembre 2027

Financé au titre de

• Digital, Industry and Space

Coût total

€ 5 957 997,50

Contribution de l’UE

€ 5 957 949,50

Coordonné par

UNIVERZITA PALACKEHO V OLOMOUCI
Czechia

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (5)

Clinical Pilot Studies Initiation Package and Ethics check

Studies registration Information, including approved protocol and other regulatory and ethics documentation. Ethics check will be carried out by the experts nominated by EC.

Conjugated MNPs/Aptamers Binding to AD Biomarkers evaluation, Version 1

Evaluation results of the binding affinity and specificity to AD biomarkers after optimised functionalisation.

MCI to AD Biomarker Deep Dive Analysis for Early Diagnosis

Detailed mapping of End-users’ Needs, Disease Challenges, and Requirements

System Architecture, Version 1

High-level system architecture and evaluation use cases design

Data Management Plan, Version 1

Procedures set for data collection, processing, monitoring, dissemination, and ethics compliance.

Publications

Conference proceedings (9)

Development of aptamer-biofunctionalized magnetic nanoparticles for the detection of Alzheimer's disease biomarkers

Auteurs: Katsipis, Georgios; Tzekaki, Eleni; Makridis, Antonios; Kazeli, Konstantina; Angelakeris, Makis; Pantazaki, Anastasia
Publié dans: 14th PICAD-6th MeCoND Proceedings, 2025
Éditeur: GAADRD
DOI: 10.5281/ZENODO.14975545

Socio-economic and clinical needs and challenges for early detection and progression monitoring of Alzheimer's disease in primary healthcare

Auteurs: Juel Holst, Gitte; Koukoura, Angeliki; Antonopoulou, Kyriaki; Tsolakis, Apostolos C.; Roma-Athanasiadou, Elli; Solomon, Alina; Tsolaki, Magda; Froelich, Lutz; Tsolaki, Anthoula; Issakainen, Mervi; Mäki-Petäjä-Leinonen, Anna; Vassiliadis, Efstathios
Publié dans: 34th Alzheimer Europe Conference, 2024
Éditeur: EVNIA
DOI: 10.5281/ZENODO.14936477

Functional coatings of magnetic nanoparticles for Alzheimer's disease applications

Auteurs: Kazeli, Konstantina; Malkaki, Foteini; Makridis, Antonios; Anastasiou, Anna; Tsamesidis, Ioannis; Malletzidou, Lamprini; Kontonasaki, Eleana; Lymperaki, Evgenia;
Publié dans: 2025
Éditeur: GAADRD
DOI: 10.5281/ZENODO.14975567

Clinical validation of a novel point-of-care diagnostic aid for early detection and monitoring of Alzheimer's Disease The Clinical protocol of 2D-BioPAD, a Horizon Europe Framework Programme

Auteurs: Tsolaki, Anthoula; Solomon, Alina; Froelich, Lutz; Juel Holst, Gitte; Tsolaki, Magda
Publié dans: 14th PICAD-6th MeCoND Proceedings, 2025
Éditeur: GAADRD
DOI: 10.5281/ZENODO.14975403

Silver Covalently Bound to Cyanographene Overcomes Bacterial Resistance to Silver Nanoparticles and Antibiotics

Auteurs: Panáček, David; Hochvaldova, Lucie; Bakandritsos, Aristides; Malina, Tomáš; Langer, Michal; Bělka, Jan; Martincová, Jana; Večeřová, Renata; Lazar, Petr; Poláková, Kateřina; Kolařík, Jan; Válková, Lucie; Kolář, Milan; Otyepka, Michal; Panacek, Ales; Zboril
Publié dans: Graphene Week 2024, 2024
Éditeur: UP-CATRIN
DOI: 10.5281/ZENODO.14971534

Synthetic controls in nanoparticles for focusing and enhancing neurodegenerative signals

Auteurs: Makridis, Antonios; Kazeli, Konstantina; Katsipis, Georgios; Tzekaki, Eleni; PANTAZAKI, Anastasia; ANGELAKERIS, MAKIS
Publié dans: 14th PICAD-6th MeCoND Proceedings, 2025
Éditeur: GAADRD
DOI: 10.5281/ZENODO.14975466

A Gold-aptamer nanoconjugate for the detection of thrombin, a potential biomarker of AD

Auteurs: Tzekaki, Eleni; Katsipis, Georgios; Kazeli, Konstantina; Makridis, Antonios; Angelakeris, Makis; Pantazaki, Anastasia
Publié dans: 14th PICAD-6th MeCoND Proceedings, 2025
Éditeur: GAADRD
DOI: 10.5281/ZENODO.14975515

Advancing Clinical and Environmental Monitoring: Graphene-Enhanced Bioreceptor Integration

Auteurs: Rossetti, Marianna; Alvarez Diduk, Ruslan; Bruno Darder; Maroli, Gabriel; Marques, Davi; de Amorim, Renê Santos; Liang, Yi-Fan; Ameda, Ana; Cenolli, Sadik; Kulla, Lueda; Broli, Nevila; Vasjari, Majlinda; Merkoçi, Arben
Publié dans: Graphene Week 2024, 2024
Éditeur: ICN2
DOI: 10.5281/ZENODO.14974753

Socio-economic and clinical needs and challenges in early detection and progression monitoring of Alzheimer's Disease in primary healthcare in Greece

Auteurs: PIkouli, Foteini Aikaterini; Juel Holst, Gitte; Koukoura, Angeliki; Antonopoulou, Kyriaki; Tsolaki, Magda
Publié dans: 14th PICAD-6th MeCoND Proceedings, 2025
Éditeur: GAADRD
DOI: 10.5281/ZENODO.14975286

Peer reviewed articles (4)

Harnessing Bioluminescent Bacteria to Develop an Enzymatic-free Enzyme-linked immunosorbent assay for the Detection of Clinically Relevant Biomarkers

Auteurs: Hu, Liming; Rossetti, Marianna; Bergua, José Francisco; Parolo, Claudio; Álvarez-Diduk, Ruslan; Rivas, Lourdes; Idili, Andrea; Merkoçi, Arben
Publié dans: ACS Applied Materials & Interfaces, 2024, ISSN 1944-8252
Éditeur: ACS
DOI: 10.1021/ACSAMI.4C01744

Single Atom Engineered Antibiotics Overcome Bacterial Resistance

Auteurs: David Panáček; Jan Belza; Lucie Hochvaldová; Zdeněk Baďura; Giorgio Zoppellaro; Martin Šrejber; Tomáš Malina; Veronika Šedajová; Markéta Paloncýová; Rostislav Langer; Lukáš Zdražil; Jianrong Zeng; Lina Li; En Zhao; Zupeng Chen; Zhiqiang Xiong; Ruibin Li; Aleš Panáček; Renata Večeřová; Pavla Kučová; Milan Kolář; Michal Otyepka; Aristides Bakandritsos; Radek Zbořil
Publié dans: Advanced Materials, 2024, ISSN 1521-4095
Éditeur: Wiley
DOI: 10.1002/ADMA.202410652

Biosensors and Bioelectronics

Auteurs: Calucho, Enric; Álvarez-Diduk, Ruslan; Piper, Andrew; Rossetti, Marianna; Nevanen, Tarja K.; Merkoçi, Arben
Publié dans: Biosensors and Bioelectronics, 2024, ISSN 0956-5663
Éditeur: Elsevier
DOI: 10.1016/J.BIOS.2024.116315

MXenes in healthcare: synthesis, fundamentals and applications

Auteurs: Zaheer Ud Din Babar; Vincenzo Iannotti; Giulio Rosati; Ayesha Zaheer; Raffaele Velotta; Bartolomeo Della Ventura; Ruslan Álvarez-Diduk; Arben Merkoçi
Publié dans: Chemical Society Reviews, 2025, ISSN 1460-4744
Éditeur: The Royal Society of Chemistry
DOI: 10.1039/D3CS01024D