Supple Graphene Bio-Platform for point-of-care early detection and monitoring of Alzheimer’s Disease

Informazioni relative al progetto

2D-BioPAD

ID dell’accordo di sovvenzione: 101120706

DOI

10.3030/101120706

Data della firma CE 29 Giugno 2023

Data di avvio 1 Ottobre 2023

Data di completamento 30 Settembre 2027

Finanziato da

• Digital, Industry and Space

Costo totale

€ 5 957 997,50

Contributo UE

€ 5 957 949,50

Coordinato da

UNIVERZITA PALACKEHO V OLOMOUCI
Czechia

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (5)

Clinical Pilot Studies Initiation Package and Ethics check

Studies registration Information, including approved protocol and other regulatory and ethics documentation. Ethics check will be carried out by the experts nominated by EC.

Conjugated MNPs/Aptamers Binding to AD Biomarkers evaluation, Version 1

Evaluation results of the binding affinity and specificity to AD biomarkers after optimised functionalisation.

MCI to AD Biomarker Deep Dive Analysis for Early Diagnosis

Detailed mapping of End-users’ Needs, Disease Challenges, and Requirements

System Architecture, Version 1

High-level system architecture and evaluation use cases design

Data Management Plan, Version 1

Procedures set for data collection, processing, monitoring, dissemination, and ethics compliance.

Pubblicazioni

Conference proceedings (9)

Development of aptamer-biofunctionalized magnetic nanoparticles for the detection of Alzheimer's disease biomarkers

Autori: Katsipis, Georgios; Tzekaki, Eleni; Makridis, Antonios; Kazeli, Konstantina; Angelakeris, Makis; Pantazaki, Anastasia
Pubblicato in: 14th PICAD-6th MeCoND Proceedings, 2025
Editore: GAADRD
DOI: 10.5281/ZENODO.14975545

Socio-economic and clinical needs and challenges for early detection and progression monitoring of Alzheimer's disease in primary healthcare

Autori: Juel Holst, Gitte; Koukoura, Angeliki; Antonopoulou, Kyriaki; Tsolakis, Apostolos C.; Roma-Athanasiadou, Elli; Solomon, Alina; Tsolaki, Magda; Froelich, Lutz; Tsolaki, Anthoula; Issakainen, Mervi; Mäki-Petäjä-Leinonen, Anna; Vassiliadis, Efstathios
Pubblicato in: 34th Alzheimer Europe Conference, 2024
Editore: EVNIA
DOI: 10.5281/ZENODO.14936477

Functional coatings of magnetic nanoparticles for Alzheimer's disease applications

Autori: Kazeli, Konstantina; Malkaki, Foteini; Makridis, Antonios; Anastasiou, Anna; Tsamesidis, Ioannis; Malletzidou, Lamprini; Kontonasaki, Eleana; Lymperaki, Evgenia;
Pubblicato in: 2025
Editore: GAADRD
DOI: 10.5281/ZENODO.14975567

Clinical validation of a novel point-of-care diagnostic aid for early detection and monitoring of Alzheimer's Disease The Clinical protocol of 2D-BioPAD, a Horizon Europe Framework Programme

Autori: Tsolaki, Anthoula; Solomon, Alina; Froelich, Lutz; Juel Holst, Gitte; Tsolaki, Magda
Pubblicato in: 14th PICAD-6th MeCoND Proceedings, 2025
Editore: GAADRD
DOI: 10.5281/ZENODO.14975403

Silver Covalently Bound to Cyanographene Overcomes Bacterial Resistance to Silver Nanoparticles and Antibiotics

Autori: Panáček, David; Hochvaldova, Lucie; Bakandritsos, Aristides; Malina, Tomáš; Langer, Michal; Bělka, Jan; Martincová, Jana; Večeřová, Renata; Lazar, Petr; Poláková, Kateřina; Kolařík, Jan; Válková, Lucie; Kolář, Milan; Otyepka, Michal; Panacek, Ales; Zboril
Pubblicato in: Graphene Week 2024, 2024
Editore: UP-CATRIN
DOI: 10.5281/ZENODO.14971534

Synthetic controls in nanoparticles for focusing and enhancing neurodegenerative signals

Autori: Makridis, Antonios; Kazeli, Konstantina; Katsipis, Georgios; Tzekaki, Eleni; PANTAZAKI, Anastasia; ANGELAKERIS, MAKIS
Pubblicato in: 14th PICAD-6th MeCoND Proceedings, 2025
Editore: GAADRD
DOI: 10.5281/ZENODO.14975466

A Gold-aptamer nanoconjugate for the detection of thrombin, a potential biomarker of AD

Autori: Tzekaki, Eleni; Katsipis, Georgios; Kazeli, Konstantina; Makridis, Antonios; Angelakeris, Makis; Pantazaki, Anastasia
Pubblicato in: 14th PICAD-6th MeCoND Proceedings, 2025
Editore: GAADRD
DOI: 10.5281/ZENODO.14975515

Advancing Clinical and Environmental Monitoring: Graphene-Enhanced Bioreceptor Integration

Autori: Rossetti, Marianna; Alvarez Diduk, Ruslan; Bruno Darder; Maroli, Gabriel; Marques, Davi; de Amorim, Renê Santos; Liang, Yi-Fan; Ameda, Ana; Cenolli, Sadik; Kulla, Lueda; Broli, Nevila; Vasjari, Majlinda; Merkoçi, Arben
Pubblicato in: Graphene Week 2024, 2024
Editore: ICN2
DOI: 10.5281/ZENODO.14974753

Socio-economic and clinical needs and challenges in early detection and progression monitoring of Alzheimer's Disease in primary healthcare in Greece

Autori: PIkouli, Foteini Aikaterini; Juel Holst, Gitte; Koukoura, Angeliki; Antonopoulou, Kyriaki; Tsolaki, Magda
Pubblicato in: 14th PICAD-6th MeCoND Proceedings, 2025
Editore: GAADRD
DOI: 10.5281/ZENODO.14975286

Peer reviewed articles (4)

Harnessing Bioluminescent Bacteria to Develop an Enzymatic-free Enzyme-linked immunosorbent assay for the Detection of Clinically Relevant Biomarkers

Autori: Hu, Liming; Rossetti, Marianna; Bergua, José Francisco; Parolo, Claudio; Álvarez-Diduk, Ruslan; Rivas, Lourdes; Idili, Andrea; Merkoçi, Arben
Pubblicato in: ACS Applied Materials & Interfaces, 2024, ISSN 1944-8252
Editore: ACS
DOI: 10.1021/ACSAMI.4C01744

Single Atom Engineered Antibiotics Overcome Bacterial Resistance

Autori: David Panáček; Jan Belza; Lucie Hochvaldová; Zdeněk Baďura; Giorgio Zoppellaro; Martin Šrejber; Tomáš Malina; Veronika Šedajová; Markéta Paloncýová; Rostislav Langer; Lukáš Zdražil; Jianrong Zeng; Lina Li; En Zhao; Zupeng Chen; Zhiqiang Xiong; Ruibin Li; Aleš Panáček; Renata Večeřová; Pavla Kučová; Milan Kolář; Michal Otyepka; Aristides Bakandritsos; Radek Zbořil
Pubblicato in: Advanced Materials, 2024, ISSN 1521-4095
Editore: Wiley
DOI: 10.1002/ADMA.202410652

Biosensors and Bioelectronics

Autori: Calucho, Enric; Álvarez-Diduk, Ruslan; Piper, Andrew; Rossetti, Marianna; Nevanen, Tarja K.; Merkoçi, Arben
Pubblicato in: Biosensors and Bioelectronics, 2024, ISSN 0956-5663
Editore: Elsevier
DOI: 10.1016/J.BIOS.2024.116315

MXenes in healthcare: synthesis, fundamentals and applications

Autori: Zaheer Ud Din Babar; Vincenzo Iannotti; Giulio Rosati; Ayesha Zaheer; Raffaele Velotta; Bartolomeo Della Ventura; Ruslan Álvarez-Diduk; Arben Merkoçi
Pubblicato in: Chemical Society Reviews, 2025, ISSN 1460-4744
Editore: The Royal Society of Chemistry
DOI: 10.1039/D3CS01024D