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Development of a multimodal toolbox to ensure a fast and reliable diagnosis of consciousness disorders

Project description

Toolbox for fast and accurate consciousness disorder diagnosis

Consciousness disorders affect the quality of life of many individuals, primarily due to the challenge of obtaining a precise diagnosis. The limited research and expertise in this field expose affected individuals to vulnerability, exacerbated by clinical time constraints that complicate the diagnostic process. Funded by the Marie Skłodowska-Curie Actions programme, the DOC-BOX project aims to support both patients and healthcare professionals by creating an innovative toolbox. This toolbox will incorporate rapid and easily deployable behavioural and neuroimaging tests, enabling doctors to assess and diagnose patients accurately and efficiently within the constraints of clinical time. Additionally, the project aims to foster research collaboration to further enhance the diagnosis and care of patients with consciousness disorders, paving the way for notable advancements in the field.

Objective

DoCBox aims to develop a new toolbox of fast and easy-to-implement behavioural, neuroimaging and neurophysiological assessments to accurately assess and diagnose patients suffering from a disorder of consciousness (DoC), allowing for a more comprehensive examination and better management of this vulnerable population. This toolbox will respond to the society needs regarding the evaluation of patients with DoC as it appropriately responds to the rigid time constraints of clinical settings, which are one of the biggest limitations for an accurate diagnosis. This project aims to enhance interdisciplinary research on DoC via an exchange of knowledge and international scientific cooperation to translate and validate the tools (e.g. behavioral scales, pipelines) that will be included in this toolbox. This collaboration between the partners underpins the credibility and feasibility of three research objectives:
1) Provide new bedside assessment tools to refine and optimize the detection of consciousness signs in post-comatose patients;
2) Identify the most accurate neurophysiological and neuroimaging biomarkers of consciousness states and develop novel easy-to-use software to implement these analyses in clinical settings;
3) Engage informal and formal caregivers in the diagnosis of DoC patients.
This will ultimately result in guidelines and policy recommendations for improvement of DoC patients diagnosis and thus care. The proposed exchange program aims to bring together a large international and interdisciplinary consortium of 17 partners (EU and non-EU countries) including researchers and other professionals with all necessary skills, permitting to tackle the challenges faced by professionals when studying and caring for DoC patients. The benefits for Europe are the intersector and interdisciplinary massive data collected by this consortium, which will allow a major progress in the understanding of (disorders of) consciousness.

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Keywords

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Topic(s)

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HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges

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Call for proposal

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(opens in new window) HORIZON-MSCA-2022-SE-01

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Coordinator

UNIVERSITE DE LIEGE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 225 400,00
Address
PLACE DU 20 AOUT 7
4000 LIEGE
Belgium

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Region
Région wallonne Prov. Liège Arr. Liège
Activity type
Higher or Secondary Education Establishments
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Total cost

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Participants (14)

Partners (1)

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