Statistical Inference from Multiscale Biological Data: theory, algorithms, applications

Informations projet

SIMBAD

N° de convention de subvention: 101131463

DOI

10.3030/101131463

Date de signature de la CE 20 Octobre 2023

Date de début 1 Decembre 2023

Date de fin 30 Novembre 2027

Financé au titre de

• Marie Skłodowska-Curie Actions (MSCA)

Coût total

Aucune donnée

Contribution de l’UE

€ 740 600,00

Coordonné par

POLITECNICO DI TORINO
Italy

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Other (1)

International School & Workshop

An international workshop allowing to share SIMBAD results with academic audiences and the broader public (via targeted events like public talks, sessions or round tables that will be organised within the meetings), and an international School providing extra training for young researchers. The School will be open to PhD students and postdocs outside SIMBAD, and will include specific time slots for fosteringing interactions and joint projects. Core topics will be quantitative studies (theoretical, computational and experimental) at the physics-biology interface, including —but not limited to— sequence-fitness landscapes, experimental evolution, pathogen evolution, optimality and tradeoffs in cell growth, origin and consequences of cell-to-cell diversity, quantitative laws for cell communities, inverse modelling epidemic networks, models of epidemic risk, advanced survival analysis models, biological design principles, mathematical approaches to inverse modelling.

Websites, patent fillings, videos etc. (1)

Project Website

Project website

Documents, reports (1)

Dissemination and Exploitation Plan

Data Management Plan (1)

Data Management Plan

Publications

Peer reviewed articles (9)

Nonequilibrium steady-state dynamics of Markov processes on graphs

Auteurs: Stefano Crotti, Thomas Barthel, Alfredo Braunstein
Publié dans: SciPost Physics, Numéro 19, 2025, ISSN 2542-4653
Éditeur: Stichting SciPost
DOI: 10.21468/SCIPOSTPHYS.19.2.045

Evolutionary emergent metabolic interactions in cell cultures: A statistical mechanics point of view

Auteurs: A. R. Batista-Tomás, C. Díaz-Faloh, R. Mulet
Publié dans: Physical Review E, Numéro 112, 2025, ISSN 2470-0045
Éditeur: American Physical Society (APS)
DOI: 10.1103/DM8R-HZMK

The advantage of periodic over constant signalling in microRNA-mediated regulation

Auteurs: Elsi Ferro, Candela L Szischik, Alejandra C Ventura, Carla Bosia
Publié dans: Nucleic Acids Research, ISSN 1362-4962
Éditeur: Oxford Academic
DOI: 10.1101/2024.04.18.590057V1.FULL.PDF

Practical debiasing with the Covariant Prior in the proportional regime when <i>p</i> &lt; <i>n</i>

Auteurs: Emanuele Massa, Anthony C C Coolen
Publié dans: Journal of Physics Communications, Numéro 9, 2025, ISSN 2399-6528
Éditeur: IOP Publishing
DOI: 10.1088/2399-6528/ADD2CD

Cross-feeding percolation phase transitions of intercellular metabolic networks

Auteurs: Luís C. F. Latoski, Andrea De Martino, Daniele De Martino
Publié dans: Science Advances, Numéro 11, 2025, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADV8216

Metabolic coordination and phase transitions in spatially distributed multi-cellular systems

Auteurs: Krishnadev Narayanankutty, José Antonio Pereiro-Morejon, Arián Ferrero-Fernández, Valentina Onesto, Stefania Forciniti, Loretta L. del Mercato, Roberto Mulet, Andrea De Martino, David S. Tourigny, Daniele De Martino
Publié dans: Communications Physics, Numéro 8, 2025, ISSN 2399-3650
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S42005-025-02133-X

Decoding cancer dynamics: Hypergraph analysis of stem cell marker interactions through O-information and community detection

Auteurs: David H. Margarit, Marcela V. Reale, Gustavo Paccosi, Lilia M. Romanelli
Publié dans: Physical Review E, Numéro 111, 2025, ISSN 2470-0045
Éditeur: American Physical Society (APS)
DOI: 10.1103/PHYSREVE.111.054410

Unveiling cancer stem cell marker networks: A hypergraph approach

Auteurs: David H. Margarit, Gustavo Paccosi, Marcela V. Reale, Lilia M. Romanelli
Publié dans: Computational Biology and Chemistry, Numéro 120, 2025, ISSN 1476-9271
Éditeur: Elsevier BV
DOI: 10.1016/J.COMPBIOLCHEM.2025.108684

SYSTEM VARIABLE REDUCTION AND GLOBAL SENSITIVITY ANALYSIS FOR A COMPLEX MODEL OF CANCER CELL DIFFERENTIATION

Auteurs: DAVID H. MARGARIT, GUSTAVO PACCOSI, ANDREA PAGNANI, MARCELA V. REALE, ARIEL F. SCAGLIOTTI, LILIA M. ROMANELLI
Publié dans: Journal of Biological Systems, Numéro 33, 2025, ISSN 0218-3390
Éditeur: World Scientific Pub Co Pte Ltd
DOI: 10.1142/S021833902550007X