Statistical Inference from Multiscale Biological Data: theory, algorithms, applications

Informazioni relative al progetto

SIMBAD

ID dell’accordo di sovvenzione: 101131463

DOI

10.3030/101131463

Data della firma CE 20 Ottobre 2023

Data di avvio 1 Dicembre 2023

Data di completamento 30 Novembre 2027

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 740 600,00

Coordinato da

POLITECNICO DI TORINO
Italy

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (1)

International School & Workshop

An international workshop allowing to share SIMBAD results with academic audiences and the broader public (via targeted events like public talks, sessions or round tables that will be organised within the meetings), and an international School providing extra training for young researchers. The School will be open to PhD students and postdocs outside SIMBAD, and will include specific time slots for fosteringing interactions and joint projects. Core topics will be quantitative studies (theoretical, computational and experimental) at the physics-biology interface, including —but not limited to— sequence-fitness landscapes, experimental evolution, pathogen evolution, optimality and tradeoffs in cell growth, origin and consequences of cell-to-cell diversity, quantitative laws for cell communities, inverse modelling epidemic networks, models of epidemic risk, advanced survival analysis models, biological design principles, mathematical approaches to inverse modelling.

Websites, patent fillings, videos etc. (1)

Project Website

Project website

Documents, reports (1)

Dissemination and Exploitation Plan

Data Management Plan (1)

Data Management Plan

Pubblicazioni

Peer reviewed articles (9)

Nonequilibrium steady-state dynamics of Markov processes on graphs

Autori: Stefano Crotti, Thomas Barthel, Alfredo Braunstein
Pubblicato in: SciPost Physics, Numero 19, 2025, ISSN 2542-4653
Editore: Stichting SciPost
DOI: 10.21468/SCIPOSTPHYS.19.2.045

Evolutionary emergent metabolic interactions in cell cultures: A statistical mechanics point of view

Autori: A. R. Batista-Tomás, C. Díaz-Faloh, R. Mulet
Pubblicato in: Physical Review E, Numero 112, 2025, ISSN 2470-0045
Editore: American Physical Society (APS)
DOI: 10.1103/DM8R-HZMK

The advantage of periodic over constant signalling in microRNA-mediated regulation

Autori: Elsi Ferro, Candela L Szischik, Alejandra C Ventura, Carla Bosia
Pubblicato in: Nucleic Acids Research, ISSN 1362-4962
Editore: Oxford Academic
DOI: 10.1101/2024.04.18.590057V1.FULL.PDF

Practical debiasing with the Covariant Prior in the proportional regime when <i>p</i> &lt; <i>n</i>

Autori: Emanuele Massa, Anthony C C Coolen
Pubblicato in: Journal of Physics Communications, Numero 9, 2025, ISSN 2399-6528
Editore: IOP Publishing
DOI: 10.1088/2399-6528/ADD2CD

Cross-feeding percolation phase transitions of intercellular metabolic networks

Autori: Luís C. F. Latoski, Andrea De Martino, Daniele De Martino
Pubblicato in: Science Advances, Numero 11, 2025, ISSN 2375-2548
Editore: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADV8216

Metabolic coordination and phase transitions in spatially distributed multi-cellular systems

Autori: Krishnadev Narayanankutty, José Antonio Pereiro-Morejon, Arián Ferrero-Fernández, Valentina Onesto, Stefania Forciniti, Loretta L. del Mercato, Roberto Mulet, Andrea De Martino, David S. Tourigny, Daniele De Martino
Pubblicato in: Communications Physics, Numero 8, 2025, ISSN 2399-3650
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S42005-025-02133-X

Decoding cancer dynamics: Hypergraph analysis of stem cell marker interactions through O-information and community detection

Autori: David H. Margarit, Marcela V. Reale, Gustavo Paccosi, Lilia M. Romanelli
Pubblicato in: Physical Review E, Numero 111, 2025, ISSN 2470-0045
Editore: American Physical Society (APS)
DOI: 10.1103/PHYSREVE.111.054410

Unveiling cancer stem cell marker networks: A hypergraph approach

Autori: David H. Margarit, Gustavo Paccosi, Marcela V. Reale, Lilia M. Romanelli
Pubblicato in: Computational Biology and Chemistry, Numero 120, 2025, ISSN 1476-9271
Editore: Elsevier BV
DOI: 10.1016/J.COMPBIOLCHEM.2025.108684

SYSTEM VARIABLE REDUCTION AND GLOBAL SENSITIVITY ANALYSIS FOR A COMPLEX MODEL OF CANCER CELL DIFFERENTIATION

Autori: DAVID H. MARGARIT, GUSTAVO PACCOSI, ANDREA PAGNANI, MARCELA V. REALE, ARIEL F. SCAGLIOTTI, LILIA M. ROMANELLI
Pubblicato in: Journal of Biological Systems, Numero 33, 2025, ISSN 0218-3390
Editore: World Scientific Pub Co Pte Ltd
DOI: 10.1142/S021833902550007X