Statistical Inference from Multiscale Biological Data: theory, algorithms, applications

Informacje na temat projektu

SIMBAD

Identyfikator umowy o grant: 101131463

DOI

10.3030/101131463

Data podpisania przez KE 20 Października 2023

Data rozpoczęcia 1 Grudnia 2023

Data zakończenia 30 Listopada 2027

Finansowanie w ramach

• Marie Skłodowska-Curie Actions (MSCA)

Koszt całkowity

Brak danych

Wkład UE

€ 740 600,00

Koordynowany przez

POLITECNICO DI TORINO
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Other (2)

International Workshop

An International Workshop focusing on SIMBAD's core topics, including —but not limited to— sequence-fitness landscapes, experimental evolution, pathogen evolution, optimality and tradeoffs in cell growth, origin and consequences of cell-to-cell diversity, quantitative laws for cell communities, inverse modelling epidemic networks, models of epidemic risk, advanced survival analysis models, biological design principles, mathematical approaches to inverse modelling

International School & Workshop

An international workshop allowing to share SIMBAD results with academic audiences and the broader public (via targeted events like public talks, sessions or round tables that will be organised within the meetings), and an international School providing extra training for young researchers. The School will be open to PhD students and postdocs outside SIMBAD, and will include specific time slots for fosteringing interactions and joint projects. Core topics will be quantitative studies (theoretical, computational and experimental) at the physics-biology interface, including —but not limited to— sequence-fitness landscapes, experimental evolution, pathogen evolution, optimality and tradeoffs in cell growth, origin and consequences of cell-to-cell diversity, quantitative laws for cell communities, inverse modelling epidemic networks, models of epidemic risk, advanced survival analysis models, biological design principles, mathematical approaches to inverse modelling.

Websites, patent fillings, videos etc. (1)

Project Website

Project website

Documents, reports (1)

Dissemination and Exploitation Plan

Data Management Plan (1)

Data Management Plan

Publikacje

Peer reviewed articles (10)

Nonequilibrium steady-state dynamics of Markov processes on graphs

Autorzy: Stefano Crotti, Thomas Barthel, Alfredo Braunstein
Opublikowane w: SciPost Physics, Numer 19, 2025, ISSN 2542-4653
Wydawca: Stichting SciPost
DOI: 10.21468/SCIPOSTPHYS.19.2.045

Evolutionary emergent metabolic interactions in cell cultures: A statistical mechanics point of view

Autorzy: A. R. Batista-Tomás, C. Díaz-Faloh, R. Mulet
Opublikowane w: Physical Review E, Numer 112, 2025, ISSN 2470-0045
Wydawca: American Physical Society (APS)
DOI: 10.1103/DM8R-HZMK

Controllable protein design via autoregressive direct coupling analysis conditioned on principal components

Autorzy: Francesco Caredda; Lisa Gennai; Paolo De Los Rios; Andrea Pagnani
Opublikowane w: PLOS Computational Biology, 2025
Wydawca: PLOS
DOI: 10.1101/2025.08.18.669886

The advantage of periodic over constant signalling in microRNA-mediated regulation

Autorzy: Elsi Ferro, Candela L Szischik, Alejandra C Ventura, Carla Bosia
Opublikowane w: Nucleic Acids Research, ISSN 1362-4962
Wydawca: Oxford Academic
DOI: 10.1101/2024.04.18.590057V1.FULL.PDF

Practical debiasing with the Covariant Prior in the proportional regime when <i>p</i> &lt; <i>n</i>

Autorzy: Emanuele Massa, Anthony C C Coolen
Opublikowane w: Journal of Physics Communications, Numer 9, 2025, ISSN 2399-6528
Wydawca: IOP Publishing
DOI: 10.1088/2399-6528/ADD2CD

Cross-feeding percolation phase transitions of intercellular metabolic networks

Autorzy: Luís C. F. Latoski, Andrea De Martino, Daniele De Martino
Opublikowane w: Science Advances, Numer 11, 2025, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADV8216

Metabolic coordination and phase transitions in spatially distributed multi-cellular systems

Autorzy: Krishnadev Narayanankutty, José Antonio Pereiro-Morejon, Arián Ferrero-Fernández, Valentina Onesto, Stefania Forciniti, Loretta L. del Mercato, Roberto Mulet, Andrea De Martino, David S. Tourigny, Daniele De Martino
Opublikowane w: Communications Physics, Numer 8, 2025, ISSN 2399-3650
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/S42005-025-02133-X

Decoding cancer dynamics: Hypergraph analysis of stem cell marker interactions through O-information and community detection

Autorzy: David H. Margarit, Marcela V. Reale, Gustavo Paccosi, Lilia M. Romanelli
Opublikowane w: Physical Review E, Numer 111, 2025, ISSN 2470-0045
Wydawca: American Physical Society (APS)
DOI: 10.1103/PHYSREVE.111.054410

Unveiling cancer stem cell marker networks: A hypergraph approach

Autorzy: David H. Margarit, Gustavo Paccosi, Marcela V. Reale, Lilia M. Romanelli
Opublikowane w: Computational Biology and Chemistry, Numer 120, 2025, ISSN 1476-9271
Wydawca: Elsevier BV
DOI: 10.1016/J.COMPBIOLCHEM.2025.108684

SYSTEM VARIABLE REDUCTION AND GLOBAL SENSITIVITY ANALYSIS FOR A COMPLEX MODEL OF CANCER CELL DIFFERENTIATION

Autorzy: DAVID H. MARGARIT, GUSTAVO PACCOSI, ANDREA PAGNANI, MARCELA V. REALE, ARIEL F. SCAGLIOTTI, LILIA M. ROMANELLI
Opublikowane w: Journal of Biological Systems, Numer 33, 2025, ISSN 0218-3390
Wydawca: World Scientific Pub Co Pte Ltd
DOI: 10.1142/S021833902550007X